Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma

American Journal of Surgery

Volumn 177, Issue 3, 1999, Pages 209-215

  Abou Shady, Mohamed ^a   Baer, Hans U ^a   Friess, Helmut ^a   Berberat, Pascal ^a   Zimmermann, Arthur ^b   Graber, Hans ^a   Gold, Leslie I ^c   Korc, Murray ^d   Büchler, Markus W ^a  

^a Dept of Visc and Transplant Surg ^*  (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c NewYork Presbyterian Hospital   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ADULT; AGED; ARTICLE; CANCER INVASION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REGULATORY MECHANISM; STROMA CELL; TUMOR CELL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ACTIVIN RECEPTORS, TYPE I; ADULT; AGED; BLOTTING, NORTHERN; CARCINOMA, HEPATOCELLULAR; CELL DIVISION; DNA PROBES; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS; MALE; MIDDLE AGED; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR CROSS-TALK; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; RNA, NEOPLASM; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032964644     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9610(99)00012-4     Document Type: Article

References (40)

1. Parkin D.M., Stjernsward J., Muir C.S. Estimates of the worldwide frequency of twelve major cancers. Bull WHO. 62:1984;163-182.
2. Sue S.R., Chari R.S., Kong F.M., et al. Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcinoma. Ann Surg. 222:1995;171-178.
3. Roberts A.B., Sporn M.B. Transforming growth factor-betas. Sporn M.B., Roberts A.B. Peptide Growth Factors and Their Receptors. Handbook of Experimental Pharmacology. Vol 95:1990;419-472 Springer, Heidelberg.
4. Russel W.E., Coffey R.J., Ouellette A.J., Moses H.L. Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc Natl Acad Sci USA. 85:1988;5126-5130.
5. Massague J. The transforming growth factor-β family. Annu Rev Cell Biol. 6:1990;597-641.
6. Bachem M.G., Meyer D., Melchior R., et al. Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblast-like cells. A potential mechanism of self perpetuation in liver fibrogenesis. J Clin Invest. 89:1992;19-27.
7. Roberts A.B., Sporn M.B., Assoian R.K., et al. Transforming growth factor type-β rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro . Proc Natl Acad Sci USA. 83:1986;4167-4171.
8. Massague J. Receptors for the TGF-beta family. Cell. 69:1992;1067-1070.
9. Lin H.Y., Wang X.F., Ng-Eaton E., et al. Expression cloning of the TGF-beta type II receptor, a functional transmembrane serin/threonine kinase. Cell. 68:1992;775-785.
10. Lopez-Casillas F., Cheifetz S., Doody J., et al. Structure and expression of the membrane proteoglycan, a component of the TGF-β receptor system. Cell. 67:1991;785-795.
11. Wang X.F., Lin H.Y., Ng-Eaton E., et al. Expression cloning and characterization of the TGF-β type III receptor. Cell. 67:1991;797-805.
12. ten Dijke P., Yamashita H., Ichijo H., et al. Characterization of type I receptors for transforming growth factor-beta and activin. Science. 264:1994;101-104.
13. Rizzino A. Understanding the roles of growth factors in carcinogenesis modulation of autocrine growth control by differentiation . Int J Dev Biol. 37:1993;61-65.
14. Ito N., Kawata S., Tamura S., et al. Elevated levels of transforming grwoth factor-β messenger RNA and its polypeptide in human hepatocellular carcinoma. Cancer Res. 51:1991;4080-4083.
15. Shirai Y., Kawata S., Tamura S., et al. Plasma transforming growth factor-β1 in patients with hepatocellular carcinoma. Cancer. 73:1994;2275-2279.
16. Inagaki M., Moustakas A., Lin H.Y., et al. Growth inhibition by transforming growth factor -β (TGF-β) type I is restored in TGF-β resistant hepatoma cells after expression of TGF-β receptor type II cDNA. Proc Natl Acad Sci USA. 90:1993;5359-5363.
17. Korc M., Chandrasekar B., Yamanaka Y., et al. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increase in the levels of epidermal growth factor and transforming growth factor alpha. J Clin Invest. 90:1992;1352-1360.
18. Friess H., Yamanaka Y., Büchler M., et al. Enhanced expression of transforming growth factor-beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology. 105:1993;1846-1856.
19. Friess H., Yamanaka Y., Büchler M., et al. Enhanced expression of type II transforming growth factor-beta receptor in human pancreatic cancer cells without alteration of type III receptor expression. Cancer Res. 53:1993;2704-2707.
20. Baldwin R.L., Friess H., Yokoyama M., et al. Attenuated ALK5 receptor expression in human pancreatic cancer correlation with resistance to growth inhibition . Int J Cancer. 67:(2):1996;283-288.
21. Pelton R.W., Saxena B., Jones M., et al. Immunohistochemical localization of TGF-β1, TGF-β2, and TGF-β3 in the mouse embryo Expression patterns suggest multiple roles during embryonic development . J Cell Biol. 115:1991;1091-1105.
22. Thoresen G.H., Refsnes M., Christoffersen T. Inhibition of hepatocyte DNA synthesis by transforming growth factor-β1 and cyclic AMP effect immediately before the G1/S border . Cancer Res. 52:1992;3598-3603.
23. Pietenpol J.A., Münger K., Howley P.M., et al. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming factor growth factor-β1 and by the retinoblastoma gene product. Proc Natl Acad Sci USA. 88:1991;10227-10231.
24. Massague J. Type-β transforming growth factor from feline sarcoma virus-transformed rat cells. J Biol Chem. 259:1984;9756-9761.
25. Gomella L.G., Sargent E.R., Wade T.P., et al. Expression of transforming growth factor alpha in normal human adult kidney and enhanced expression of transforming growth factors alpha and beta1 in renal cell carcinoma. Cancer Res. 49:1989;6972-6975.
26. Barrett-Lee P., Travers M., Luqmani Y., Coombes R.C. Transcripts for transforming growth factors in human breast cancer clinical correlates . Br J Cancer. 61:1990;612-617.
27. Vogelbruch M., Wellmann A., Maschek H., et al. Transforming growth factor-β1 in human liver tumors. Verh Dtsch Ges Path. 79:1995;132-136.
28. Huggett A.C., Ellis P.A., Ford C.P., et al. Development of resistance to the growth inhibitory effects of transforming growth factor β1 during the spontaneous transformation of rat liver epithelial cells. Cancer Res. 51:1991;5929-5936.
29. Sporn M.B., Roberts A.B., Wakefield L.M., Cromburgghe B. Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol. 195:1987;1039-1045.
30. Grupposo P.A., Mead J.E., Fausto N. Transforming growth factor receptors in liver regeneration following partial hepatectomy in the rat. Cancer Res. 50:1990;1464-1469.
31. Yang E.Y., Moses H.L. Transforming growth factor-β1-induced changes in cell migration, proliferation and angiogensis in the chicken chorioallantoic membrane. J Cell Biol. 111:1990;731-741.
32. Ito N., Kawata S., Tamura S., et al. Positive correlation of plasma transforming growth factor-β1 levels with tumor vascularity in hepatocellular carcinoma. Cancer Lett. 89:1995;45-48.
33. Ueki N., Nakazato M., Ohkawa T., et al. Excessive production of transforming growth factor-β1 can play an important role in the development of tumorigenesis by its action for angiogenesis validity of neutralizing antibodies to block tumor growth . Biochim Biophys Acta. 1137:1992;189-196.
34. De Martin R., Haendler B., Hofer-Warbinek R., et al. Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family. EMBO J. 6:1987;3673-3677.
35. Baldwin R.L., Korc M. Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1. Growth Factors. 8:1993;23-34.
36. Nakatsukasa H., Evarts R.P., Hsia C.C., et al. Expression of transforming growth factor-β1 during chemical hepatocarcinogenesis in the rat. Lab Invest. 65:1991;511-517.
37. Roberts A.B., Thompson N.L., Heine U., et al. Transforming growth factor β possible roles in carcinogenesis . Br J Cancer. 57:1988;594-600.
38. Fey M.F., Topler A. Tumor heterogeneity and clonality - an old theme revisited. Ann Oncol. 7:1996;121-128.
39. Bassing C.H., Yingling J.M., Wang X.F. Receptors for the TGF-β ligand family. Vitam Horm. 48:1994;111-156.
40. Bedossa P., Peltier E., Terris B., et al. Transforming growth factor-beta1 and TGF-beta1 receptors in normal, cirrhotic, and neoplastic human livers. Hepatology. 21:1995;760-766.