-
1
-
-
0027503601
-
Physiological actions and clinical applications of transforming growth factor-β (TGF-β)
-
Roberts AB and Sporn MB: Physiological actions and clinical applications of transforming growth factor-β (TGF-β). Growth Factors 8: 1-9, 1993.
-
(1993)
Growth Factors
, vol.8
, pp. 1-9
-
-
Roberts, A.B.1
Sporn, M.B.2
-
2
-
-
0028359376
-
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin
-
Cárcamo J, Weis FM, Ventura F, Wieser R, Wrana JL, Attisano L and Massagué J: Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin. Mol Cell Biol 14: 3810-3821, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3810-3821
-
-
Cárcamo, J.1
Weis, F.M.2
Ventura, F.3
Wieser, R.4
Wrana, J.L.5
Attisano, L.6
Massagué, J.7
-
3
-
-
0028059199
-
Homomeric interactions between type II transforming growth factor-β receptor
-
Chen R-H and Derynck R: Homomeric interactions between type II transforming growth factor-β receptor. J Biol Chem 269: 22868-22874, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 22868-22874
-
-
Chen, R.-H.1
Derynck, R.2
-
4
-
-
0028170226
-
Mechanism of activation of the TGF-β receptor
-
Wrana JL, Attisano L, Wieser R, Ventura F and Massagué J: Mechanism of activation of the TGF-β receptor. Nature 370: 341-347, 1994.
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Wieser, R.3
Ventura, F.4
Massagué, J.5
-
5
-
-
0030816043
-
TGF-β signalling through the Smad pathway
-
Massagué J, Hata A and Liu F: TGF-β signalling through the Smad pathway. Trends Cell Biol 7: 187-192, 1997.
-
(1997)
Trends Cell Biol
, vol.7
, pp. 187-192
-
-
Massagué, J.1
Hata, A.2
Liu, F.3
-
6
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGF-β regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert K, Scherer SW, Ozcelik H, Pirone R, Hoodless P, Kim H, Tsui LC, Bapat B, Gallinger S, Andrulis IL, Thomsen GH, Wrana JL and Attisano L: MADR2 maps to 18q21 and encodes a TGF-β regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86: 543-552, 1996.
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
Pirone, R.4
Hoodless, P.5
Kim, H.6
Tsui, L.C.7
Bapat, B.8
Gallinger, S.9
Andrulis, I.L.10
Thomsen, G.H.11
Wrana, J.L.12
Attisano, L.13
-
7
-
-
0029786212
-
Receptor associated Mad homologues synergize as effectors of the TGF-β response
-
Zhang Y, Feng X-H, Wu R-Y and Derynck R: Receptor associated Mad homologues synergize as effectors of the TGF-β response. Nature 383: 168-172, 1996.
-
(1996)
Nature
, vol.383
, pp. 168-172
-
-
Zhang, Y.1
Feng, X.-H.2
Wu, R.-Y.3
Derynck, R.4
-
8
-
-
0030768644
-
TGF-β receptor-mediated signalling through Smad2, Smad3 and Smad4
-
Nakao A, Imamura T, Souchelnytskyi S, Kawabata M, Ishisaki A, Oeda E, Tamaki K, Hanai J, Heldin C-H, Miyazono K and ten Dijke P: TGF-β receptor-mediated signalling through Smad2, Smad3 and Smad4. EMBO J 16: 5353-5362, 1997.
-
(1997)
EMBO J
, vol.16
, pp. 5353-5362
-
-
Nakao, A.1
Imamura, T.2
Souchelnytskyi, S.3
Kawabata, M.4
Ishisaki, A.5
Oeda, E.6
Tamaki, K.7
Hanai, J.8
Heldin, C.-H.9
Miyazono, K.10
Ten Dijke, P.11
-
9
-
-
0029892494
-
MADR1, a MAD-related protein that functions in BMP2 signaling pathways
-
Hoodless PA, Haerry T, Abdollah S, Stapleton M, O'Connor MB, Attisano L and Wrana JL: MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 85: 489-500, 1996.
-
(1996)
Cell
, vol.85
, pp. 489-500
-
-
Hoodless, P.A.1
Haerry, T.2
Abdollah, S.3
Stapleton, M.4
O'Connor, M.B.5
Attisano, L.6
Wrana, J.L.7
-
10
-
-
0029931509
-
A human Mad protein acting as a BMP-regulated transcriptional activator
-
Liu F, Hata A, Baker JC, Doody J, Carcamo J, Harland RM and Massagué J: A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381: 620-623, 1996.
-
(1996)
Nature
, vol.381
, pp. 620-623
-
-
Liu, F.1
Hata, A.2
Baker, J.C.3
Doody, J.4
Carcamo, J.5
Harland, R.M.6
Massagué, J.7
-
11
-
-
0030911104
-
The TGF-β family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
-
Kretzschmar M, Liu F, Hata A, Doody J and Massagué J: The TGF-β family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes Dev 11: 984-995, 1997.
-
(1997)
Genes Dev
, vol.11
, pp. 984-995
-
-
Kretzschmar, M.1
Liu, F.2
Hata, A.3
Doody, J.4
Massagué, J.5
-
12
-
-
0031939744
-
Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12
-
Nishimura R, Kato Y, Chen D, Harris SE, Mundy GR and Yoneda T: Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12. J Biol Chem 273: 1872-1879, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 1872-1879
-
-
Nishimura, R.1
Kato, Y.2
Chen, D.3
Harris, S.E.4
Mundy, G.R.5
Yoneda, T.6
-
13
-
-
0031569819
-
Smad5 induces ventral fates in Xenopus embryo
-
Suzuki A, Chang C, Yingling JM, Wang W-F and Hemmati-Brivanlou A: Smad5 induces ventral fates in Xenopus embryo. Dev Biol 84: 402-405, 1997.
-
(1997)
Dev Biol
, vol.84
, pp. 402-405
-
-
Suzuki, A.1
Chang, C.2
Yingling, J.M.3
Wang, W.-F.4
Hemmati-Brivanlou, A.5
-
14
-
-
0031570714
-
Cloning and characterization of a novel member of the human MAD gene family
-
Watanabe TK, Suzuki M, Omori Y, Hishigaki H, Horie M, Kanemoto N, Fujiwara T, Nakamura Y and Takahashi E: Cloning and characterization of a novel member of the human MAD gene family. Genomics 42: 446-451, 1997.
-
(1997)
Genomics
, vol.42
, pp. 446-451
-
-
Watanabe, T.K.1
Suzuki, M.2
Omori, Y.3
Hishigaki, H.4
Horie, M.5
Kanemoto, N.6
Fujiwara, T.7
Nakamura, Y.8
Takahashi, E.9
-
15
-
-
0029834067
-
Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways
-
Lagna G, Hata A, Hammati-Brivanlou A and Massagué J: Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 383: 832-836, 1996.
-
(1996)
Nature
, vol.383
, pp. 832-836
-
-
Lagna, G.1
Hata, A.2
Hammati-Brivanlou, A.3
Massagué, J.4
-
16
-
-
0030974042
-
Heteromeric and homomeric interactions correlate with signalling activity and functional cooperativity of Smad3 and Smad4/DPCA
-
Wu R-Y, Zhang Y, Feng X-H and Derynck R: Heteromeric and homomeric interactions correlate with signalling activity and functional cooperativity of Smad3 and Smad4/DPCA. Mol Cell Biol 17: 2521-2528, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2521-2528
-
-
Wu, R.-Y.1
Zhang, Y.2
Feng, X.-H.3
Derynck, R.4
-
17
-
-
0030611757
-
Identification of Smad7, a TGF-β-inducable antagonist of TGF-β signalling
-
Nakao A, Afrakthe M, Morén A, Nakayama T, Christian JL, Heuchel R, Itho S, Kawabata M, Heldin N-E, Heldin C-H and ten Dijke P: Identification of Smad7, a TGF-β-inducable antagonist of TGF-β signalling. Nature 389: 631-635, 1997.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakthe, M.2
Morén, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itho, S.7
Kawabata, M.8
Heldin, N.-E.9
Heldin, C.-H.10
Ten Dijke, P.11
-
18
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGFβ signalling
-
Hayashi H, Abdollah S, Qiu Y, Cai J, Xu YY, Grinnell BW, Richardson MA, Topper JN, Gimbrone MA Jr, Wrana JL and Falb D: The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGFβ signalling. Cell 89: 1165-1173, 1997.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
Cai, J.4
Xu, Y.Y.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone Jr., M.A.9
Wrana, J.L.10
Falb, D.11
-
19
-
-
12644260471
-
Vascular MADs: Two novel MAD-related genes selectively inducable by flow in human vascular endothelium
-
Topper JN, Cai J, Qiu Y, Anderson KR, Xu YY, Deeds JD, Feeley R, Gimeno CJ, Woolf EA, Tayber O, Mays GG, Sampson BA, Schoen FJ, Gimbrone MA Jr and Falb D: Vascular MADs: two novel MAD-related genes selectively inducable by flow in human vascular endothelium. Proc Natl Acad Sci USA 94: 9314-9319, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9314-9319
-
-
Topper, J.N.1
Cai, J.2
Qiu, Y.3
Anderson, K.R.4
Xu, Y.Y.5
Deeds, J.D.6
Feeley, R.7
Gimeno, C.J.8
Woolf, E.A.9
Tayber, O.10
Mays, G.G.11
Sampson, B.A.12
Schoen, F.J.13
Gimbrone Jr., M.A.14
Falb, D.15
-
20
-
-
0030825516
-
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4
-
Hata A, Lo RS, Wotton D, Lagna G and Massagué J: Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature 388: 82-87, 1997.
-
(1997)
Nature
, vol.388
, pp. 82-87
-
-
Hata, A.1
Lo, R.S.2
Wotton, D.3
Lagna, G.4
Massagué, J.5
-
21
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus via Smad proteins
-
Heldin C-H, Miyazono K and ten Dijke P: TGF-β signalling from cell membrane to nucleus via Smad proteins. Nature 390: 465-471, 1997.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.-H.1
Miyazono, K.2
Ten Dijke, P.3
-
22
-
-
0023852747
-
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
-
Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A and Fusenig NE: Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 106: 761-771, 1988.
-
(1988)
J Cell Biol
, vol.106
, pp. 761-771
-
-
Boukamp, P.1
Petrussevska, R.T.2
Breitkreutz, D.3
Hornung, J.4
Markham, A.5
Fusenig, N.E.6
-
23
-
-
0025373886
-
Biological effects and binding properties of transforming growth factor-β on human oral squamous cell carcinoma cells
-
Ichijo H, Momose F and Miyazono K: Biological effects and binding properties of transforming growth factor-β on human oral squamous cell carcinoma cells. Exp Cell Res 187: 263-269, 1990.
-
(1990)
Exp Cell Res
, vol.187
, pp. 263-269
-
-
Ichijo, H.1
Momose, F.2
Miyazono, K.3
-
24
-
-
0021961480
-
The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders
-
Pulford KA, Gatter KC and Mason DY: The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders. Histopathology 9: 825-844, 1985.
-
(1985)
Histopathology
, vol.9
, pp. 825-844
-
-
Pulford, K.A.1
Gatter, K.C.2
Mason, D.Y.3
-
25
-
-
0027332995
-
Cloning of a TGFβ type I receptor that forms a heterodimeric complex with the TGFβ type II receptor
-
Franzén P, ten Dijke P, Ichijo H, Yamashita H, Schulz P, Heldin C-H and Miyazono K: Cloning of a TGFβ type I receptor that forms a heterodimeric complex with the TGFβ type II receptor. Cell 75: 681-692, 1993.
-
(1993)
Cell
, vol.75
, pp. 681-692
-
-
Franzén, P.1
Ten Dijke, P.2
Ichijo, H.3
Yamashita, H.4
Schulz, P.5
Heldin, C.-H.6
Miyazono, K.7
-
26
-
-
0027393417
-
Involvement of transforming growth factor-β in the formation of fibrotic lesions in carcinoid heart disease
-
Waltenberger J, Lundin L, Öberg K, Wilander E, Miyazono K, Heldin C-H and Funa K: Involvement of transforming growth factor-β in the formation of fibrotic lesions in carcinoid heart disease. Am J Pathol 142: 71-78, 1993.
-
(1993)
Am J Pathol
, vol.142
, pp. 71-78
-
-
Waltenberger, J.1
Lundin, L.2
Öberg, K.3
Wilander, E.4
Miyazono, K.5
Heldin, C.-H.6
Funa, K.7
-
27
-
-
0027199448
-
Induction of transforming growth factor-β during cardiac allograft rejection
-
Waltenberger J, Wanders A, Fellström B, Miyazono K, Heldin C-H and Funa K: Induction of transforming growth factor-β during cardiac allograft rejection. J Immunol 151: 1147-1157, 1993.
-
(1993)
J Immunol
, vol.151
, pp. 1147-1157
-
-
Waltenberger, J.1
Wanders, A.2
Fellström, B.3
Miyazono, K.4
Heldin, C.-H.5
Funa, K.6
-
28
-
-
0029879560
-
Expression of transforming growth factor β isoforms and their receptors during hair growth phases in mice
-
Wollina U, Lange D, Funa K and Paus R: Expression of transforming growth factor β isoforms and their receptors during hair growth phases in mice. Histol Histopathol 11: 431-436, 1996.
-
(1996)
Histol Histopathol
, vol.11
, pp. 431-436
-
-
Wollina, U.1
Lange, D.2
Funa, K.3
Paus, R.4
-
29
-
-
0030927098
-
Dysregulated expression of transforming growth factor β and its type-I and type-II receptors in basal-cell carcinoma
-
Furue M, Kato M, Nakamura K, Nashiro K, Kikuchi K, Okochi H, Miyazono K and Tamaki K: Dysregulated expression of transforming growth factor β and its type-I and type-II receptors in basal-cell carcinoma. Int J Cancer 71: 505-509, 1997.
-
(1997)
Int J Cancer
, vol.71
, pp. 505-509
-
-
Furue, M.1
Kato, M.2
Nakamura, K.3
Nashiro, K.4
Kikuchi, K.5
Okochi, H.6
Miyazono, K.7
Tamaki, K.8
-
31
-
-
0032531281
-
TGF-β receptor expression on human keratinocytes: A 150 kDa GPI-anchored TGF-β1 binding protein forms a heteromeric complex with type I and type II receptors
-
Tam BY, Germain L and Philip A: TGF-β receptor expression on human keratinocytes: a 150 kDa GPI-anchored TGF-β1 binding protein forms a heteromeric complex with type I and type II receptors. J Cell Biochem 70: 573-586, 1998.
-
(1998)
J Cell Biochem
, vol.70
, pp. 573-586
-
-
Tam, B.Y.1
Germain, L.2
Philip, A.3
-
32
-
-
0032500010
-
Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development
-
Amendt C, Schirmacher P, Weber H and Blessing M: Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development. Oncogene 17: 25-34, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 25-34
-
-
Amendt, C.1
Schirmacher, P.2
Weber, H.3
Blessing, M.4
-
33
-
-
15844386165
-
Mutations of the human homologue of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden AB, Gillies S, Negus K, Smyth I, Pressman C, Leffell DJ, Gerrard B, Goldstein AM, Dean M, Toftgard R, Chevenix-Trench G, Wainwright B and Bale AE: Mutations of the human homologue of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85: 841-851, 1996.
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulous, P.G.3
Gailani, M.R.4
Shanley, S.5
Chidambaram, A.6
Vorechovsky, I.7
Holmberg, E.8
Unden, A.B.9
Gillies, S.10
Negus, K.11
Smyth, I.12
Pressman, C.13
Leffell, D.J.14
Gerrard, B.15
Goldstein, A.M.16
Dean, M.17
Toftgard, R.18
Chevenix-Trench, G.19
Wainwright, B.20
Bale, A.E.21
more..
-
34
-
-
0030922980
-
Characterization of functional domains within Smad4/DPC4
-
De Caestecker MP, Hemmati P, Larisch-Block S, Ajmera R, Roberts AB and Lechleider RJ: Characterization of functional domains within Smad4/DPC4. J Biol Chem 272: 13690-13696, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 13690-13696
-
-
De Caestecker, M.P.1
Hemmati, P.2
Larisch-Block, S.3
Ajmera, R.4
Roberts, A.B.5
Lechleider, R.J.6
-
35
-
-
15844387270
-
Mad-related genes in the human
-
Riggins GJ, Thiagalingam S, Rozenblum E, Weinstein CL, Kern SE, Hamilton SR, Willson JK, Markowitz SD, Kinzler KW and Vogelstein B: Mad-related genes in the human. Nat Genet 13: 347-349, 1996.
-
(1996)
Nat Genet
, vol.13
, pp. 347-349
-
-
Riggins, G.J.1
Thiagalingam, S.2
Rozenblum, E.3
Weinstein, C.L.4
Kern, S.E.5
Hamilton, S.R.6
Willson, J.K.7
Markowitz, S.D.8
Kinzler, K.W.9
Vogelstein, B.10
-
37
-
-
0029806078
-
Regulation of transforming growth factor β- And activin-induced transcription by mammalian MAD proteins
-
Chen Y, Lebrun JJ and Vale W: Regulation of transforming growth factor β- and activin-induced transcription by mammalian MAD proteins. Proc Natl Acad Sci USA 93: 12992-12997, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12992-12997
-
-
Chen, Y.1
Lebrun, J.J.2
Vale, W.3
-
38
-
-
0031916811
-
Conversion of normal human oral keratinocytes to tumorigenic cells is associated with the acquisition of resistance to TGF-β
-
Woo KM, Lee G, Kook JK and Min BM: Conversion of normal human oral keratinocytes to tumorigenic cells is associated with the acquisition of resistance to TGF-β. Int J Oncol 12: 833-839, 1998.
-
(1998)
Int J Oncol
, vol.12
, pp. 833-839
-
-
Woo, K.M.1
Lee, G.2
Kook, J.K.3
Min, B.M.4
-
39
-
-
0025021804
-
Induction and autocrine-receptor binding of transforming growth factor-β2 during terminal differentiation of primary mouse keratinocytes
-
Glick AB, Danielpour D, Morgan D, Sporn MB and Yuspa SH: Induction and autocrine-receptor binding of transforming growth factor-β2 during terminal differentiation of primary mouse keratinocytes. Mol Endocrinol 4: 46-52, 1990.
-
(1990)
Mol Endocrinol
, vol.4
, pp. 46-52
-
-
Glick, A.B.1
Danielpour, D.2
Morgan, D.3
Sporn, M.B.4
Yuspa, S.H.5
-
40
-
-
0026682527
-
Skin distribution and differential expression of transforming growth factor β1 and β2
-
Falanga V, Gerhardt CO, Dasch JR, Takehara K and Ksander GA: Skin distribution and differential expression of transforming growth factor β1 and β2. J Dermatol Sci 3: 131-136, 1992.
-
(1992)
J Dermatol Sci
, vol.3
, pp. 131-136
-
-
Falanga, V.1
Gerhardt, C.O.2
Dasch, J.R.3
Takehara, K.4
Ksander, G.A.5
-
41
-
-
0027333290
-
TGF-βs and TGF-β type-II receptor in the human epidermis: Differential expression in acute and chronic wounds
-
Schmid P, Cox D, Bilbe G, McMaster G, Morrison C, Stahelin H, Luscher N and Seiler W: TGF-βs and TGF-β type-II receptor in the human epidermis: differential expression in acute and chronic wounds. J Pathol 171: 191-197, 1993.
-
(1993)
J Pathol
, vol.171
, pp. 191-197
-
-
Schmid, P.1
Cox, D.2
Bilbe, G.3
McMaster, G.4
Morrison, C.5
Stahelin, H.6
Luscher, N.7
Seiler, W.8
-
42
-
-
0028351248
-
Elevated expression of type-VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-β
-
Rudnicka L, Varga J, Christiano AM, Iozzo RV, Jimenez SA and Uitto J: Elevated expression of type-VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-β. J Clin Invest 93: 1709-1715, 1994.
-
(1994)
J Clin Invest
, vol.93
, pp. 1709-1715
-
-
Rudnicka, L.1
Varga, J.2
Christiano, A.M.3
Iozzo, R.V.4
Jimenez, S.A.5
Uitto, J.6
-
43
-
-
0029070821
-
A human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-β and insulin-like growth factor binding protein-6, in a calcium- and cell-densitity-dependent manner
-
Kato M, Ihizaki A, Hellmann U, Wernstedt C, Kyogoku M, Miyazano K, Heldin H-C and Funa K: A human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-β and insulin-like growth factor binding protein-6, in a calcium- and cell-densitity-dependent manner. J Biol Chem 270: 12373-12379, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 12373-12379
-
-
Kato, M.1
Ihizaki, A.2
Hellmann, U.3
Wernstedt, C.4
Kyogoku, M.5
Miyazano, K.6
Heldin, H.-C.7
Funa, K.8
-
44
-
-
0030886204
-
Transforming growth factor β-induced phosphorylation of Samd3 is required for growth inhibition and transcriptional induction in epithelial cells
-
Liu X, Sun Y, Constantinescu SN, Karam E, Weinberg RA and Lodish HF: Transforming growth factor β-induced phosphorylation of Samd3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc Natl Acad Sci USA 94: 10669-10674, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10669-10674
-
-
Liu, X.1
Sun, Y.2
Constantinescu, S.N.3
Karam, E.4
Weinberg, R.A.5
Lodish, H.F.6
-
45
-
-
0031317650
-
Cell cycle regulation and abnormalities in epidermal tumors
-
Heenen M: Cell cycle regulation and abnormalities in epidermal tumors. Ann Dermatol Venereol 124: 452-456, 1997.
-
(1997)
Ann Dermatol Venereol
, vol.124
, pp. 452-456
-
-
Heenen, M.1
-
46
-
-
0032474586
-
TGF-β effects on proliferation of rat intestinal cells are due to inhibition of cyclin D1 expression
-
Ko TC, Yu W, Sakai T, Sheng H, Shao J, Beauchamp RD and Thompson EA: TGF-β effects on proliferation of rat intestinal cells are due to inhibition of cyclin D1 expression. Oncogene 16: 3445-3454, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 3445-3454
-
-
Ko, T.C.1
Yu, W.2
Sakai, T.3
Sheng, H.4
Shao, J.5
Beauchamp, R.D.6
Thompson, E.A.7
-
47
-
-
0011102935
-
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
-
Stone DM, Hynes M, Armanini M, Swanson TA, Gu Q, Johnson RL, Scott MP, Pennica D, Goddard A, Phillips H, Noll M, Hooper JE, de Sauvage F and Rosenthal A: The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384: 129-134, 1996.
-
(1996)
Nature
, vol.384
, pp. 129-134
-
-
Stone, D.M.1
Hynes, M.2
Armanini, M.3
Swanson, T.A.4
Gu, Q.5
Johnson, R.L.6
Scott, M.P.7
Pennica, D.8
Goddard, A.9
Phillips, H.10
Noll, M.11
Hooper, J.E.12
De Sauvage, F.13
Rosenthal, A.14
-
48
-
-
0030296921
-
Local delivery of TGFβ2 can substitute for placode epithelium to induce mesenchymal condensation during skin appendage morphogenesis
-
Ting-Berreth SA and Chuong CM: Local delivery of TGFβ2 can substitute for placode epithelium to induce mesenchymal condensation during skin appendage morphogenesis. Dev Biol 179: 347-359, 1996.
-
(1996)
Dev Biol
, vol.179
, pp. 347-359
-
-
Ting-Berreth, S.A.1
Chuong, C.M.2
-
49
-
-
0030027059
-
Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
-
Goodrich LV, Johnson RL, Milenkovic L, McMahon JA and Scott MP: Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev 10: 301-312, 1996.
-
(1996)
Genes Dev
, vol.10
, pp. 301-312
-
-
Goodrich, L.V.1
Johnson, R.L.2
Milenkovic, L.3
McMahon, J.A.4
Scott, M.P.5
-
50
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH and Kern SE: DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271: 350-353, 1996.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
51
-
-
0031837549
-
Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome
-
Aszterbaum M, Rothman A, Johnson RL, Fisher M, Xie J, Bonifas JM, Zhang X, Scott MP and Epstein EH Jr: Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome. J Invest Dermatol 110: 885-888, 1998.
-
(1998)
J Invest Dermatol
, vol.110
, pp. 885-888
-
-
Aszterbaum, M.1
Rothman, A.2
Johnson, R.L.3
Fisher, M.4
Xie, J.5
Bonifas, J.M.6
Zhang, X.7
Scott, M.P.8
Epstein Jr., E.H.9
-
52
-
-
0029841366
-
Mutations in the human homologue of Drosophila patched (PCTH) in basal cell carcinomas and the Gorlin syndrome: Different in vivo mechanisms of PCTH activation
-
Unden AB, Holmber E, Lundh-Rozell B, Stahle-Backdahl M, Zaphiropoulos PG, Toftgard R and Vorechovsky I: Mutations in the human homologue of Drosophila patched (PCTH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PCTH activation. Cancer Res 56: 4562-4565, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 4562-4565
-
-
Unden, A.B.1
Holmber, E.2
Lundh-Rozell, B.3
Stahle-Backdahl, M.4
Zaphiropoulos, P.G.5
Toftgard, R.6
Vorechovsky, I.7
-
53
-
-
0031913524
-
Activating smoothened mutations in sporadic basal-cell carcinoma
-
Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, Bonifas JM, Lam CW, Hynes M, Goddard A, Rosenthal A, Epstein EH Jr and de Sauvage FJ: Activating smoothened mutations in sporadic basal-cell carcinoma. Nature 391: 90-92, 1998.
-
(1998)
Nature
, vol.391
, pp. 90-92
-
-
Xie, J.1
Murone, M.2
Luoh, S.M.3
Ryan, A.4
Gu, Q.5
Zhang, C.6
Bonifas, J.M.7
Lam, C.W.8
Hynes, M.9
Goddard, A.10
Rosenthal, A.11
Epstein Jr., E.H.12
De Sauvage, F.J.13
-
54
-
-
0030297553
-
Dual role for patched in sequestering and transducing Hegdehog
-
Chen Y and Struhl G: Dual role for patched in sequestering and transducing Hegdehog. Cell 87: 553-563, 1996.
-
(1996)
Cell
, vol.87
, pp. 553-563
-
-
Chen, Y.1
Struhl, G.2
-
55
-
-
1842330252
-
Trichoepitheliomas contain somatic mutations in the overexpressed PTCH-gene: Support for a gatekeeper mechanism in tumorigenesis
-
Vorechovsky I, Unden AB, Sandstedt B, Toftgart R and Stahle-Bachdahl M: Trichoepitheliomas contain somatic mutations in the overexpressed PTCH-gene: support for a gatekeeper mechanism in tumorigenesis. Cancer Res 57: 4677-4681, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 4677-4681
-
-
Vorechovsky, I.1
Unden, A.B.2
Sandstedt, B.3
Toftgart, R.4
Stahle-Bachdahl, M.5
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