SCOPUS 정보 검색 플랫폼

Current Medicinal Chemistry

Volumn 8, Issue 12, 2001, Pages 1487-1503

Cell cycle regulation in the G1 phase: A promising target for the development of new chemotherapeutic anticancer agents

(4) Owa, Takashi a Yoshino, Hiroshi a Yoshimatsu, Kentaro a Nagasu, Takeshi a

a EISAI CO LTD (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

17 ALLYLAMINOGELDANAMYCIN; 2 (3 CHLOROANILINO) 4 [2 (3 HYDROXYPROPYLAMINO) 4 PYRIDYL]PYRIMIDINE; 3 BENZYL 7 CYANO 2,3,4,5 TETRAHYDRO 1 (1H IMIDAZOL 4 YLMETHYL) 4 (2 THIENYLSULFONYL) 1H 1,4 BENZODIAZEPINE; 7 HYDROXYSTAUROSPORINE; ANTINEOPLASTIC AGENT; BORTEZOMIB; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; CYTOSTATIC AGENT; FLAVOPIRIDOL; FR 901228; FUMAGILLOL CHLOROACETYLCARBAMATE; HISTONE; HISTONE DEACETYLASE INHIBITOR; INDISULAM; LONAFARNIB; MESSENGER RNA; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PROTEASOME INHIBITOR; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN KINASE; PROTEIN P21; RAPAMYCIN; RAPAMYCIN DERIVATIVE; S6 KINASE; TEMSIROLIMUS; TIPIFARNIB; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CANCER CHEMOTHERAPY; CANCER RESEARCH; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL TRIAL; DIARRHEA; DOWN REGULATION; DRUG STRUCTURE; DRUG TARGETING; GASTROINTESTINAL TOXICITY; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HYPERGLYCEMIA; HYPERLIPIDEMIA; HYPOTENSION; LUNG TOXICITY; MALIGNANT TRANSFORMATION; MOUSE; NAUSEA; NEUROTOXICITY; NEUTROPENIA; NONHUMAN; ONCOGENE RAS; PHASE 1 CLINICAL TRIAL; PROTEIN DEGRADATION; REGULATORY MECHANISM; SOLID TUMOR; THROMBOCYTOPENIA; UROGENITAL TRACT CANCER; UTERINE CERVIX CANCER;

EID: 0034820022 PISSN: 09298673 EISSN: None Source Type: Journal
DOI: 10.2174/0929867013371996 Document Type: Article

Times cited : (162)

References (193)

1
- 0004099712
- W.H. Freeman: New York
- (1993) The Cell Cycle
- Murray, A.¹ Hunt, T.²

2
- 0027172322
- (1993) Cell , vol.74 , pp. 777
- Williams, G.T.¹ Smith, C.A.²

3
- 0019225636
- (1980) Int. Rev. Cytol. , vol.68 , pp. 251
- Wyllie, A.H.¹ Kerr, J.F.² Currie, A.R.³

4
- 0004099105
- American Chemical Society: Washington, DC
- (1995) Cancer Chemotherapeutic Agents
- Foye, W.O.¹

5
- 0003659024
- Chemotherapy of Neoplastic Diseases
- Hardman, J.G., Gilman, A.G., Limbird, L.E., Eds.; MacMillan: New York
- (1985) Goodman and Gilman's the Pharmacological Basis of Therapeutics , pp. 1240-1306
- Calabresi, P.¹ Parks, R.E.²

6
- 0016701089
- (1975) J. Biol. Chem. , vol.250 , pp. 9276
- Lee, J.C.¹ Harrison, D.² Timasheff, S.N.³

7
- 0019333189
- (1980) Biochemistry , vol.19 , pp. 5550
- Margolis, R.L.¹ Rauch, C.T.² Wilson, L.³

8
- 0027360552
- (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 9552
- Jordan, M.A.¹ Toso, R.J.² Thrower, D.³ Wilson, L.⁴

9
- 0027942033
- (1994) J. Cell Biol. , vol.127 , pp. 1301
- Rieder, C.L.¹ Schultz, A.² Cole, R.³ Sluder, G.⁴

10
- 0032189055
- (1998) Biochim. Biophys. Acta , vol.1400 , pp. 107
- Takimoto, C.H.¹ Wright, J.² Arbuck, S.G.³

11
- 0031040149
- (1997) Annu. Rev. Med. , vol.48 , pp. 353
- Rowinsky, E.K.¹

12
- 0029849620
- (1996) Science , vol.274 , pp. 1672
- Sherr, C.J.¹

13
- 0002315291
- Principles and Practice of Oncology
- DeVita, V.T., Hellman, S., Rosenberg, S.A., Eds.; Lippincott-Raven: Philadelphia
- (1997) Cancer , pp. 79-102
- Perkins, A.S.¹ Stern, D.F.²

14
- 0028828204
- (1995) Adv. Cancer Res. , vol.55 , pp. 181
- Pines, J.¹

15
- 0033957960
- (2000) Exp. Opin. Ther. Patents , vol.10 , pp. 215
- Rosania, G.R.¹ Chang, Y.-T.²

16
- 0032588170
- (1999) Mol. Cell. Biol. , vol.19 , pp. 2690
- Hinz, M.¹ Krappmann, D.² Eichten, A.³ Heder, A.⁴ Scheidereit, C.⁵ Strauss, M.⁶

17
- 0029807944
- (1996) Science , vol.274 , pp. 1652
- King, R.W.¹ Deshaies, R.J.² Peters, J.³ Kirschner, M.W.⁴

18
- 0028675322
- (1994) Chem. Biol. , vol.1 , pp. 191
- Murray, A.W.¹

19
- 0027994603
- (1994) Cell , vol.78 , pp. 713
- Fisher, R.P.¹ Morgan, D.O.²

20
- 0033022375
- (1999) Cell. Mol. Life Sci. , vol.55 , pp. 284
- Kaldis, P.¹

21
- 0028954227
- (1995) Nature , vol.374 , pp. 283
- Shiekhattar, R.¹ Mermelstein, F.² Fisher, R.P.³ Drapkin, R.⁴ Dynlacht, B.⁵ Wessling, H.C.⁶ Morgan, D.O.⁷ Reinberg, D.⁸

22
- 0028590113
- (1994) Cell , vol.79 , pp. 1103
- Feaver, W.J.¹ Svejstrup, J.Q.² Henry, N.L.³ Kornberg, R.D.⁴

23
- 0029038903
- (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 5174
- Makela, T.P.¹ Parvin, J.D.² Kim, J.³ Huber, L.J.⁴ Sharp, P.A.⁵ Weinberg, R.A.⁶

24
- 0028912931
- (1995) Mol. Cell. Biol. , vol.15 , pp. 2288
- Wang, Z.¹ Buratowski, S.² Svejstrup, J.Q.³ Feaver, W.J.⁴ Wu, X.⁵ Kornberg, R.D.⁶ Donahue, T.F.⁷ Friedberg, E.C.⁸

25
- 0028885363
- (1995) Cell , vol.80 , pp. 21
- Svejstrup, J.Q.¹ Wang, Z.² Feaver, W.J.³ Wu, X.⁴ Bushnell, D.A.⁵ Donahue, T.F.⁶ Friedberg, E.C.⁷ Kornberg, R.D.⁸

26
- 0003590571
- (1995) Mol. Biol. Cell , vol.6 , pp. 1333
- Meuller, P.R.¹ Coleman, T.R.² Dunphy, W.G.³

27
- 0026616796
- (1992) Science , vol.257 , pp. 1955
- Parker, L.L.¹ Piwnica-Worms, H.²

28
- 0028135173
- (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 877
- Coleman, T.R.¹ Dunphy, W.G.²

29
- 0343742594
- (1997) Biochim. Biophys. Acta , vol.1332
- Draetta, G.¹ Eckstein, J.²

30
- 0024425887
- (1989) Science , vol.246 , pp. 629
- Hartwell, L.H.¹ Weinert, T.A.²

31
- 0029808466
- (1996) Science , vol.274 , pp. 1664
- Elledge, S.J.¹

32
- 0027970713
- (1994) Genes Dev. , vol.8 , pp. 2540
- Di Leonardo, A.¹ Linke, S.P.² Clarkin, K.³ Wahl, G.M.⁴

33
- 0030657690
- (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 768
- Planas-Silva, M.D.¹ Weinberg, R.A.²

34
- 0032496322
- (1998) Science , vol.280 , pp. 909
- Boddy, M.N.¹ Furnari, B.² Mondesert, O.³ Russell, P.⁴

35
- 0032483576
- (1998) Cell , vol.94 , pp. 595
- Huang, M.¹ Zhou, Z.² Elledge, S.J.³

36
- 0032190082
- (1998) Nature , vol.395 , pp. 507
- Zeng, Y.¹ Forbes, K.C.² Wu, Z.³ Moreno, S.⁴ Piwnica-Worms, H.⁵ Enoch, T.⁶

37
- 0032996507
- (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 69
- Amon, A.¹

38
- 0031600105
- (1998) Trends Genet. , vol.14 , pp. 1
- Hardwick, K.G.¹

39
- 0029910364
- (1996) Mol. Cell. Biol. , vol.16 , pp. 6917
- Lukas, J.¹ Bartkova, J.² Bartek, J.³

40
- 0029033861
- (1995) Cell , vol.81 , pp. 323
- Weinberg, R.A.¹

41
- 0032931991
- (1999) Mol. Cell. Biol , vol.19 , pp. 3246
- Brown, V.D.¹ Phillips, R.A.² Gallie, B.L.³

42
- 0029125622
- (1995) J. Cell. Biol. , vol.130 , pp. 755
- Jackson, P.K.¹ Chevalier, S.² Phillippe, M.³ Kirschner, M.W.⁴

43
- 0027768579
- (1993) Cell , vol.75 , pp. 839
- Hunter, T.¹

44
- 0033564697
- (1999) Genes Dev. , vol.13 , pp. 1501
- Sherr, C.J.¹ Roberts, J.M.²

45
- 0030609861
- (1997) Science , vol.291 , pp. 831
- Brown, J.P.¹ Wei, W.² Sedivy, J.M.³

46
- 0028168242
- (1994) Nature , vol.371 , pp. 257
- Hannon, G.J.¹ Beach, D.H.²

47
- 0028179669
- (1994) Genes Dev. , vol.8 , pp. 9
- Polyak, K.¹ Kato, J.Y.² Solomon, M.J.³ Sherr, C.J.⁴ Massague, J.⁵ Roberts, J.M.⁶ Koff, A.⁷

48
- 0027973043
- (1994) Cell , vol.79 , pp. 487
- Kato, J.Y.¹ Matsuoka, M.² Polyak, K.³ Massague, J.⁴ Sherr, C.J.⁵

49
- 0028176483
- (1994) Cell , vol.78 , pp. 59
- Polyak, K.¹ Lee, M.H.² Erdjument-Bromage, H.³ Koff, A.⁴ Roberts, J.M.⁵ Tempst, P.⁶ Massague, J.⁷

50
- 0027717617
- (1993) Nature , vol.366 , pp. 701
- Xiong, Y.¹ Hannon, G.J.² Zhang, H.³ Casso, D.⁴ Kobayashi, R.⁵ Beach, D.H.⁶

51
- 0027496935
- (1993) Cell , vol.75 , pp. 805
- Harper, J.W.¹ Adami, G.R.² Wei, N.³ Keyomarsi, K.⁴ Elledge, S.J.⁵

52
- 0029664461
- (1996) Science , vol.272 , pp. 877
- Coats, S.¹ Flanagan, W.M.² Nourse, J.³ Roberts, J.M.⁴

53
- 0030955563
- (1997) Genes Dev. , vol.11 , pp. 973
- Yan, Y.¹ Frisen, J.² Lee, M.H.³ Massague, J.⁴ Barbacid, M.⁵

54
- 0029052951
- (1995) Nature , vol.375 , pp. 506
- Koh, J.¹ Enders, G.H.² Dynlacht, B.D.³ Harlow, E.⁴

55
- 0028918388
- (1995) Mol. Cell. Biol. , vol.15 , pp. 2672
- Hirai, H.¹ Roussel, M.F.² Kato, J.Y.³ Ashmun, R.A.⁴ Sherr, C.J.⁵

56
- 0028911830
- (1995) Mol. Cell. Biol. , vol.15 , pp. 2682
- Chan, F.K.¹ Zhang, J.² Cheng, L.³ Shapiro, D.N.⁴ Winoto, A.⁵

57
- 0027769876
- (1993) Nature , vol.366 , pp. 704
- Serrano, M.¹ Hannon, G.J.² Beach, D.H.³

58
- 0025611503
- (1990) Science , vol.250 , pp. 1576
- Chen, P.L.¹ Chen, Y.M.² Bookstein, R.³ Lee, W.H.⁴

59
- 0026669469
- (1992) Cell , vol.70 , pp. 523
- Vogelstein, B.¹ Kinzler, K.W.²

60
- 0029921317
- (1996) Adv. Cancer Res. , vol.56 , pp. 67
- Hall, M.¹ Peters, G.²

61
- 0028033270
- (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 11045
- Okamoto, A.¹ Demetrick, D.J.² Spillare, E.A.³ Hagiwara, K.⁴ Hussain, S.P.⁵ Bennett, W.P.⁶ Forrester, K.⁷ Gerwin, B.⁸ Serrano, M.⁹ Beach, D.H.¹⁰ Harris, C.C.¹¹

62
- 0028059330
- (1994) Nat. Genet. , vol.8 , pp. 27
- Caldas, C.¹ Hahn, S.A.² Da Costa, L.T.³ Redston, M.S.⁴ Schutte, M.⁵ Seymour, A.B.⁶ Weinstein, C.L.⁷ Hruban, R.H.⁸ Yeo, C.J.⁹ Kern, S.E.¹⁰

63
- 0028100903
- (1994) Nat. Genet. , vol.8 , pp. 15
- Hussussian, C.J.¹ Struewing, J.P.² Goldstein, A.M.³ Higgins, P.A.⁴ Ally, D.S.⁵ Sheahan, M.D.⁶ Clark M.H., Jr.⁷ Tucker, M.A.⁸ Dracopoli, N.C.⁹

64
- 0028331092
- (1994) Cancer Res. , vol.54 , pp. 1812
- Gillett, C.¹ Fantl, V.² Smith, R.³ Fisher, C.⁴ Bartek, J.⁵ Dickson, C.⁶ Barnes, D.⁷ Peters, G.⁸

65
- 0032126542
- (1998) Cancer Res. , vol.58 , pp. 2876
- Oyama, T.¹ Kashiwabara, K.² Yoshimoto, K.³ Arnold, A.⁴ Koerner, F.⁵

66
- 0032859124
- (1999) Br. J. Cancer , vol.81 , pp. 127
- Keum, J.S.¹ Kong, G.² Yang, S.C.³ Shin, D.H.⁴ Park, S.S.⁵ Lee, J.H.⁶ Lee, J.D.⁷

67
- 0031841384
- (1998) Nucleic Acids Res. , vol.26 , pp. 205
- Hainaut, P.¹ Hernandez, T.² Robinson, A.³ Rodriguez-Tome, P.⁴ Flores, T.⁵ Hollstein, M.⁶ Harris, C.C.⁷ Montesano, R.⁸

68
- 0031435944
- (1997) Genes Dev. , vol.11 , pp. 3471
- Siliciano, J.D.¹ Canman, C.E.² Taya, Y.³ Sakaguchi, K.⁴ Appella, E.⁵ Kastan, M.B.⁶

69
- 0032508504
- (1998) Science , vol.281 , pp. 1674
- Banin, S.¹ Moyal, L.² Shieh, S.³ Taya, Y.⁴ Anderson, S.W.⁵ Chessa, L.⁶ Smorodinsky, N.I.⁷ Prives, C.⁸ Reiss, Y.⁹ Shiloh, Y.¹⁰ Ziv, Y.¹¹

70
- 0032508608
- (1998) Science , vol.281 , pp. 1677
- Canman, C.E.¹ Lim, D.S.² Cimprich, K.A.³ Taya, Y.⁴ Tamai, K.⁵ Sakaguchi, K.⁶ Appella, E.⁷ Kastan, M.B.⁸ Siliciano, J.D.⁹

71
- 0034629072
- (2000) Science , vol.287 , pp. 1824
- Hirao, A.¹ Kong, Y.Y.² Matsuoka, S.³ Wakeham, A.⁴ Ruland, J.⁵ Yoshida, H.⁶ Liu, D.⁷ Elledge, S.J.⁸ Mak, T.W.⁹

72
- 0034142325
- (2000) Genes Dev. , vol.14 , pp. 278
- Chehab, N.H.¹ Malikzay, A.² Appel, M.³ Halazonetis, T.D.⁴

73
- 0034142034
- (2000) Genes Dev. , vol.14 , pp. 289
- Shieh, S.Y.¹ Ahn, J.² Tamai, K.³ Taya, Y.⁴ Prives, C.⁵

75
- 0029665778
- (1996) Cancer Res. , vol.56 , pp. 2973
- Carlson, B.A.¹ Durbay, M.M.² Sausville, E.A.³ Brizuela, L.⁴ Worland, P.J.⁵

76
- 0028176485
- (1994) Biochem. Biophys. Res. Commun. , vol.201 , pp. 589
- Losiewicz, M.D.¹ Carlson, B.A.² Kaur, G.³ Sausville, E.A.⁴ Worland, P.J.⁵

77
- 0029993339
- (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 2735
- De Azevedo W.F., Jr.¹ Mueller-Dieckmann, H.J.² Schulze-Gahmen, U.³ Worland, P.J.⁴ Sausville, E.A.⁵ Kim, S.H.⁶

78
- 0002633950
- (1996) Ann. Rep. Med. Chem. , vol.32 , pp. 171
- Coleman, K.G.¹ Lyssikatos, J.P.² Yang, B.V.³

79
- 0031809781
- (1998) Exp. Opin. Invest. Drugs , vol.7 , pp. 865
- Webster, K.R.¹

80
- 0033375469
- (1999) Invest. New Drugs , vol.17 , pp. 313
- Senderowicz, A.M.¹

81
- 0032055497
- (1998) Blood , vol.91 , pp. 2482
- Arguello, F.¹ Alexander, M.² Sterry, J.A.³ Tudor, G.⁴ Smith, E.M.⁵ Kalavar, N.T.⁶ Greene J.F., Jr.⁷ Koss, W.⁸ Morgan, C.D.⁹ Stinson, S.F.¹⁰ Siford, T.J.¹¹ Alvord, G.¹² Klabansky, R.L.¹³ Sausville, E.A.¹⁴

82
- 0031670668
- (1998) J. Clin. Oncol. , vol.16 , pp. 2986
- Senderowicz, A.M.¹ Headlee, D.² Stinson, S.F.³ Lush, R.M.⁴ Kalil, N.⁵ Villalba, L.⁶ Hill, K.⁷ Steinberg, S.M.⁸ Figg, W.D.⁹ Tompkins, A.¹⁰ Arbuck, S.G.¹¹ Sausville, E.A.¹²

83
- 85037381326
- Flavopiridol and Other New Anticancer Drugs in Phase I/II at the NCI. The 4th International Symposium on Cancer Chemotherapy, Tokyo, Japan, Dec 2
- (1999) , pp. 34-35
- Sausville, E.A.¹

84
- 0028990479
- (1995) Cell Growth Differ. , vol.6 , pp. 927
- Wang, Q.¹ Worland, P.J.² Clark, J.L.³ Carlson, B.A.⁴ Sausville, E.A.⁵

85
- 0029871688
- (1996) Biochem. Biophys. Res. Commun. , vol.219 , pp. 778
- Kawakami, K.¹ Futani, H.² Takahara, J.³ Yamaguchi, K.⁴

86
- 0030615323
- (1997) Cancer Res. , vol.57 , pp. 1495
- Akiyama, T.¹ Yoshida, T.² Tsujita, T.³ Shimizu, M.⁴ Mizukami, T.⁵ Okabe, M.⁶ Akinaga, S.⁷

87
- 0032509403
- (1998) J. Biol. Chem. , vol.273 , pp. 33455
- Yu, L.¹ Orlandi, L.² Wang, P.³ Orr, M.S.⁴ Senderowics, A.M.⁵ Sausville, E.A.⁶ Silvestrini, R.⁷ Watanabe, N.⁸ Piwnica-Worms, H.⁹ O'connor, P.M.¹⁰

88
- 0034655281
- (2000) Cancer Res. , vol.60 , pp. 2108
- Busby, E.C.¹ Leistritz, D.F.² Abraham, R.T.³ Karnitz, L.M.⁴ Sarkaria, J.N.⁵

89
- 0030768948
- (1997) Science , vol.277 , pp. 1495
- Furnari, B.¹ Rhind, N.² Russell, P.³

90
- 0030611095
- (1997) Science , vol.277 , pp. 1501
- Peng, C.Y.¹ Graves, P.R.² Thomas, R.S.³ Wu, Z.⁴ Shaw, A.S.⁵ Piwnica-Worms, H.⁶

91
- 0030867582
- (1997) Science , vol.277 , pp. 1497
- Sanchez, Y.¹ Wong, C.² Thomas, R.S.³ Richman, R.⁴ Wu, Z.⁵ Piwnica-Worms, H.⁶ Elledge, S.J.⁷

92
- 0029895439
- (1996) J. Natl. Cancer Inst. , vol.88 , pp. 956
- Wang, Q.¹ Fan, S.² Eastman, A.³ Worland, P.J.⁴ Sausville, E.A.⁵ O'connor, P.M.⁶

93
- 0034677755
- (2000) Science , vol.287 , pp. 1969
- Gibbs, J.B.¹

94
- 0030961614
- (1997) Curr. Biol. , vol.7 , pp. 82
- Wade, P.A.¹ Wolffe, A.P.²

95
- 0030916336
- (1997) Cell , vol.89 , pp. 325
- Pazin, M.J.¹ Kadonaga, J.T.²

96
- 0031244521
- (1997) Curr. Opin. Chem. Biol. , vol.1 , pp. 300
- Hassig, C.A.¹ Schreiber, S.L.²

97
- 0030798245
- (1997) Nature , vol.389 , pp. 349
- Grunstein, M.¹

98
- 0033427145
- (1999) Ann. N. Y. Acad. Sci. , vol.886 , pp. 195
- Sowa, Y.¹ Orita, T.² Hiranabe-Minamikawa, S.³ Nakano, K.⁴ Mizuno, T.⁵ Nomura, H.⁶ Sakai, T.⁷

99
- 0029932598
- (1996) Science , vol.272 , pp. 408
- Taunton, J.¹ Hassig, C.A.² Schreiber, S.L.³

100
- 0032549001
- (1998) Cell , vol.92 , pp. 463
- Luo, R.X.¹ Postigo, A.A.² Dean, D.C.³

101
- 0017767153
- (1977) Nature , vol.268 , pp. 462
- Riggs, M.G.¹ Whittaker, R.G.² Neumann, J.R.³ Ingram, V.M.⁴

102
- 0000032126
- (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 3356
- Kwon, H.J.¹ Owa, T.² Hassig, C.A.³ Shimada, J.⁴ Schreiber, S.L.⁵

103
- 0029294663
- (1995) Bioessays , vol.17 , pp. 423
- Yoshida, M.¹ Horinouchi, S.² Beppu, T.³

104
- 0033000990
- (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 40
- Kouzarides, T.¹

105
- 0033539092
- (1999) Nature , vol.401 , pp. 188
- Finnin, M.S.¹ Donigian, J.R.² Cohen, A.³ Richon, V.M.⁴ Rifkind, R.A.⁵ Marks, P.A.⁶ Breslow, R.⁷ Pavletich, N.P.⁸

106
- 0028258610
- (1994) J. Antibiot. , vol.47 , pp. 301
- Ueda, H.¹ Nakajima, H.² Hori, Y.³ Fujita, T.⁴ Nishimura, M.⁵ Goto, T.⁶ Okuhara, M.⁷

107
- 0344431240
- (1998) Exp. Cell Res. , vol.241 , pp. 126
- Nakajima, H.¹ Kim, Y.B.² Terano, H.³ Yoshida, M.⁴ Horinouchi, S.⁵

108
- 0028267278
- (1994) J. Antibiot. , vol.47 , pp. 315
- Ueda, H.¹ Manda, T.² Matsumoto, S.³ Mukumoto, S.⁴ Nishigaki, F.⁵ Kawamura, I.⁶ Shimomura, K.⁷

109
- 0033551152
- (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 4592
- Saito, A.¹ Yamashita, T.² Mariko, Y.³ Nosaka, Y.⁴ Tsuchiya, K.⁵ Ando, T.⁶ Suzuki, T.⁷ Tsuruo, T.⁸ Nakanishi, O.⁹

110
- 0032539890
- (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 3003
- Richon, V.M.¹ Emiliani, S.² Verdin, E.³ Webb, Y.⁴ Breslow, R.⁵ Rifkind, R.A.⁶ Marks, P.A.⁷

111
- 0000658923
- 808
- (2000) Proc. Am. Assoc. Cancer Res. , vol.41
- Richon, V.M.¹ Sandhoff, T.W.² Rifkind, R.A.³ Marks, P.A.⁴

112
- 0029867623
- (1996) Trends Biochem. Sci. , vol.21 , pp. 96
- Hilt, W.¹ Wolf, D.H.²

113
- 0027980321
- (1994) Cell , vol.78 , pp. 773
- Palombella, V.J.¹ Rando, O.J.² Goldberg, A.L.³ Maniatis, T.⁴

114
- 0029591482
- (1995) Annu. Rev. Genet. , vol.29 , pp. 729
- Monaco, J.J.¹ Nandi, D.²

115
- 0029807944
- (1996) Science , vol.274 , pp. 1652
- King, R.W.¹ Deshaies, R.J.² Peters, J.M.³ Kirschner, M.W.⁴

116
- 0031973765
- (1998) Br. J. Cancer , vol.77 , pp. 448
- Spataro, V.¹ Norbury, C.² Harris, A.L.³

117
- 0033152760
- (1999) Cancer Res. , vol.59 , pp. 2615
- Adams, J.¹ Palombella, V.J.² Sausville, E.A.³ Johnson, J.⁴ Destree, A.⁵ Lazarus, D.D.⁶ Maas, J.⁷ Pien, C.S.⁸ Prakash, S.⁹ Elliott, P.J.¹⁰

118
- 85037398038
- (1999) Proc. Am. Soc. Clin. Oncol. , vol.18
- Elliott, P.J.¹

119
- 0032885416
- (1999) Clin. Cancer Res , vol.5 , pp. 2638
- Teicher, B.A.¹ Ara, G.² Herbst, R.³ Palombella, V.J.⁴ Adams, J.⁵

120
- 0023068346
- (1987) Annu. Rev. Biochem. , vol.56 , pp. 779
- Barbacid, M.¹

121
- 0025838675
- (1991) Annu. Rev. Cell Biol. , vol.7 , pp. 601
- Bollag, G.¹ McCormick, F.²

122
- 0027239613
- (1993) Annu. Rev. Biochem. , vol.62 , pp. 851
- Lowy, D.R.¹ Willumsen, B.M.²

123
- 0024406286
- (1989) Cell , vol.57 , pp. 1167
- Hancock, J.F.¹ Magee, J.E.² Marshall, C.J.³

124
- 0028331587
- (1994) Cell , vol.77 , pp. 175
- Gibbs, J.B.¹ Oliff, A.² Kohl, N.³

125
- 0000206984
- (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 8223
- Casey, P.J.¹ Solski, P.A.² Der, C.I.³ Buss, J.E.⁴

126
- 0030865773
- (1997) J. Med. Chem. , vol.40 , pp. 2971
- Leonard, D.M.¹

127
- 0032696858
- (1999) Drugs Future , vol.24 , pp. 1099
- Leonard, D.M.¹ Sebolt-Leopold, J.S.²

128
- 0033986112
- (2000) J. Clin. Invest. , vol.105 , pp. 9
- Gibbs, J.B.¹

129
- 0032539559
- (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 1369
- Moasser, M.M.¹ Sepp-Lorenzino, L.² Kohl, N.E.³ Oliff, A.⁴ Balog, A.⁵ Su, D.S.⁶ Danishefsky, S.J.⁷ Rosen, N.⁸

130
- 0032439623
- (1998) Oncogene , vol.17 , pp. 3359
- Muschel, R.J.¹ Soto, D.E.² McKenna, W.G.³ Bernhard, E.J.⁴

132
- 0033214457
- (1999) Cancer Res. , vol.59 , pp. 4919
- Sun, J.¹ Blaskovich, M.A.² Knowles, D.³ Qian, Y.⁴ Ohkanda, J.⁵ Bailey, R.D.⁶ Hamilton, A.D.⁷ Sebti, S.M.⁸

134
- 0034071688
- (2000) Cancer Res. , vol.60 , pp. 1871
- Adjei, A.A.¹ Erlichman, C.² Davis, J.N.³ Cutler, D.L.⁴ Sloan, J.A.⁵ Marks, R.S.⁶ Hanson, L.J.⁷ Svingen, P.A.⁸ Atherton, P.⁹ Bishop, W.R.¹⁰ Kirschmeier, P.¹¹ Kaufmann, S.H.¹²

135
- 0000179878
- 270
- (1998) Proc. Am. Assoc. Cancer Res. , vol.39
- End, D.¹ Skrzat, S.² Devine, A.³ Angibaud, P.⁴ Venet, M.⁵ Sanz, G.⁶ Bowden, C.⁷

136
- 0000179877
- 317
- (1998) Proc. Am. Assoc. Cancer Res. , vol.39
- Skrzat, S.¹ Angibaud, P.² Venet, M.³ Sanz, G.⁴ Bowden, C.⁵ End, D.⁶

137
- 0000535592
- (1999) Proc. Am. Soc. Clin, Oncol. , vol.18
- Hudes, G.R.¹

138
- 25044472704
- (1999) Proc. Am. Soc. Clin, Oncol. , vol.18
- Zujewskk, J.¹

139
- 0003221837
- (1999) Proc. Am. Soc. Clin, Oncol. , vol.18
- Peeters, M.¹

140
- 25044440678
- 445
- (2000) Proc. Am. Assoc. Cancer Res. , vol.41
- Manne, V.¹ Ricca, C.² Gullo-Brown, J.³ Penhallow, B.⁴ Carboni, J.⁵ Lynch, M.⁶

141
- 4243978862
- 446
- (2000) Proc. Am. Assoc. Cancer Res. , vol.41
- Rose, W.C.¹ Arico, M.A.² Burke, C.L.³ Clark, J.L.⁴ Fager, K.L.⁵ VanDeren, C.⁶ Kramer, R.A.⁷ Lee, F.Y.F.⁸

142
- 0032589825
- (1999) Bull. Cancer , vol.86 , pp. 808
- Alexandre, J.¹ Raymond, E.² Armand, J.P.³

143
- 0028360374
- (1994) Nature , vol.369 , pp. 756
- Brown, E.J.¹ Albers, M.W.² Shin, T.B.³ Ichikawa, K.⁴ Keith, C.T.⁵ Lane, W.S.⁶ Schreiber, S.L.⁷

144
- 0028239893
- (1994) Cell , vol.78 , pp. 35
- Sabatini, D.M.¹ Erdjument Bromage, H.² Lui, M.³ Tempst, P.⁴ Snyder, S.H.⁵

145
- 0027311858
- (1993) Cell , vol.73 , pp. 585
- Kunz, J.¹ Henriquez, R.² Schneider, U.³ Deuter Reinhard, M.⁴ Movva, N.R.⁵ Hall, M.N.⁶

146
- 0028786952
- (1995) EMBO J. , vol.14 , pp. 5701
- Haghighat, A.¹ Mader, S.² Pause, A.³ Sonenberg, N.⁴

147
- 0026659046
- (1992) Cell , vol.69 , pp. 1227
- Chung, J.¹ Kuo, C.J.² Crabtree, G.R.³ Blenis, J.⁴

148
- 0000375616
- 301
- (1999) Proc. Am. Assoc. Cancer Res. , vol.40
- Gibbson, J.J.¹ Discafani, C.² Peterson, R.³ Hernandez, R.⁴ Skotnicki, J.⁵ Frost, P.⁶

149
- 85037386789
- AACR-NCI-EORTC, The International Conference on Molecular Targets and Cancer Therapeutics: Discovery, Development, and Clinical Validation, Washington, DC, Nov 16-19
- (1999)
- Alexandre, J.¹

150
- 0022967572
- (1986) Mol. Cell. Biol. , vol.6 , pp. 2198
- Uehara, Y.¹ Hori, M.² Takeuchi, T.³ Umezawa, H.⁴

151
- 0028064940
- (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 8324
- Whitesell, L.¹ Mimnaugh, E.G.² De Costa, B.³ Myers, C.E.⁴ Neckers, L.M.⁵

152
- 0031005361
- (1997) Cell , vol.89 , pp. 239
- Stebbins, C.E.¹ Russo, A.A.² Schneider, C.³ Rosen, N.⁴ Hartl, F.U.⁵ Pavletich, N.P.⁶

153
- 0029963674
- (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 14536
- Schneider, C.¹ Sepp-Lorenzino, L.² Nimmersgen, E.³ Ouerfelli, O.⁴ Danishefsky, S.J.⁵ Rosen, N.⁶ Hartl, F.U.⁷

154
- 0029812759
- (1996) J. Biol. Chem. , vol.271 , pp. 22796
- Mimnaugh, E.¹ Chavany, C.² Neckers, L.M.³

155
- 0029973294
- (1996) Mol. Endocrinol. , vol.10 , pp. 705
- Whitesell, L.¹ Cook, P.²

156
- 0028786332
- (1995) J. Biol. Chem. , vol.270 , pp. 24585
- Schulte, T.W.¹ Blagosklonny, M.V.² Ingui, C.³ Neckers, L.M.⁴

157
- 0034655207
- (2000) Cancer Res. , vol.60 , pp. 2090
- Zheng, F.F.¹ Kuduk, S.D.² Chiosis, G.³ Münster, P.N.⁴ Sepp-Lorenzino, L.⁵ Danishefsky, S.J.⁶ Rosen, N.⁷

158
- 0028929803
- (1995) Nature Med. , vol.1 , pp. 27
- Folkman, J.¹

159
- 0026083903
- (1991) N. Engl. J. Med. , vol.324 , pp. 1
- Weidner, N.¹ Semple, J.P.² Welch, W.³ Folkman, J.⁴

160
- 0025204095
- (1990) Nature , vol.348 , pp. 555
- Ingber, D.¹ Fujita, T.² Kishimoto, S.³ Sudo, K.⁴ Kanamaru, T.⁵ Brem, H.⁶ Folkman, J.⁷

161
- 0028176358
- (1994) Cancer Res. , vol.54 , pp. 3407
- Abe, J.¹ Zhou, W.² Takuwa, N.³ Taguchi, J.⁴ Kurokawa, K.⁵ Kumada, M.⁶ Takuwa, Y.⁷

162
- 0028013224
- (1994) Br. J. Cancer , vol.69 , pp. 212
- Kusaka, M.¹ Sudo, K.² Matsutani, E.³ Kozai, Y.⁴ Marui, S.⁵ Fujita, T.⁶ Ingber, D.⁷ Folkman, J.⁸

163
- 0026082066
- (1991) Biochem. Biophys. Res. Commun. , vol.174 , pp. 1070
- Kusaka, M.¹ Sudo, K.² Fujita, T.³ Marui, S.⁴ Itoh, F.⁵ Ingbar, D.⁶ Folkman, J.⁷

164
- 0028868220
- (1995) Cancer Res. , vol.55 , pp. 836
- Tanaka, T.¹ Konno, H.² Matsuda, I.³ Nakamura, S.⁴ Baba, S.⁵

165
- 0027487871
- (1993) Cancer Res. , vol.53 , pp. 5233
- Yamaoka, M.¹ Yamamoto, T.² Ikeyama, S.³ Sudo, K.⁴ Fujita, T.⁵

166
- 0027174375
- (1993) Cancer Res , vol.53 , pp. 2566
- Yanase, T.¹ Tamura, M.² Fujita, K.³ Kodama, S.⁴ Tanaka, K.⁵

167
- 0028359292
- (1994) Neurosurgery , vol.34 , pp. 869
- Takamiya, Y.¹ Brem, H.² Ojeifo, J.³ Mineta, T.⁴ Martuza, R.L.⁵

168
- 0027413495
- (1993) J. Neurosurg. , vol.78 , pp. 470
- Takamiya, Y.¹ Friedlander, R.M.² Brem, H.³ Malick, A.⁴ Martuza, R.L.⁵

169
- 0030924753
- (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 6099
- Sin, N.¹ Meng, L.² Wang, M.Q.W.³ Wen, J.J.⁴ Bornmann, W.G.⁵ Crews, C.M.⁶

170
- 0031171961
- (1997) Chem. Biol. , vol.4 , pp. 461
- Griffith, E.C.¹ Su, Z.² Turk, B.E.³ Chen, S.⁴ Chang, Y.-H.⁵ Wu, Z.⁶ Biemann, K.⁷ Liu, J.O.⁸

171
- 85037383981
- 98
- (1998) Proc. Am. Assoc. Cancer Res. , vol.39
- Wang, J.¹ Quan, N.² Henkin, J.³

172
- 0030816274
- (1997) Clin. Cancer Res. , vol.3 , pp. 1501
- Kudelka, A.P.¹ Levy, T.² Verschraegen, C.F.³ Edwards, C.L.⁴ Piamsomboon, S.⁵ Termrungruanglert, W.⁶ Freedman, R.S.⁷ Kaplan, A.L.⁸ Kieback, D.G.⁹ Meyers, C.A.¹⁰ Jaeckle, K.A.¹¹ Loyer, E.¹² Steger, M.¹³ Mante, R.¹⁴ Mavligit, G.¹⁵ Killian, A.¹⁶ Tang, J.U.¹⁷ Kavanagh, J.J.¹⁸

173
- 6544276582
- (1999) Clin. Cancer Res. , vol.5 , pp. 1989
- Bhargava, P.¹ Marshall, J.L.² Rizvi, N.³ Dahut, W.⁴ Yoe, J.⁵ Figuera, M.⁶ Phipps, K.⁷ Ong, V.S.⁸ Kato, A.⁹ Hawkins, M.J.¹⁰

174
- 0032767386
- (1999) J. Clin. Oncol. , vol.17 , pp. 2541
- Stadler, W.M.¹ Kuzel, T.² Shapiro, C.³ Sosman, J.⁴ Clark, J.⁵ Vogelzang, N.J.⁶

175
- 0033598320
- (1999) J. Med. Chem. , vol.42 , pp. 3789
- Owa, T.¹ Yoshino, H.² Okauchi, T.³ Yoshimatsu, K.⁴ Ozawa, Y.⁵ Sugi, N.H.⁶ Nagasu, T.⁷ Koyanagi, N.⁸ Kitoh, K.⁹

176
- 0034608622
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 1223
- Owa, T.¹ Okauchi, T.² Yoshimatsu, K.³ Sugi, N.H.⁴ Ozawa, Y.⁵ Nagasu, T.⁶ Koyanagi, N.⁷ Okabe, T.⁸ Kitoh, K.⁹ Yoshino, H.¹⁰

177
- 0026719782
- (1992) J. Med. Chem. , vol.35 , pp. 2496
- Yoshino, H.¹ Ueda, N.² Niijima, J.³ Sugumi, H.⁴ Kotake, Y.⁵ Koyanagi, N.⁶ Yoshimatsu, K.⁷ Asada, M.⁸ Watanabe, T.⁹ Nagasu, T.¹⁰ Tsukahara, K.¹¹ Iijima, A.¹² Kitoh, K.¹³

178
- 0030756156
- (1997) Cancer Res. , vol.57 , pp. 3208
- Yoshimatsu, K.¹ Yamaguchi, A.² Yoshino, H.³ Koyanagi, N.⁴ Kitoh, K.⁵

179
- 0028351192
- (1994) Cancer Res. , vol.54 , pp. 1702
- Koyanagi, N.¹ Nagasu, T.² Fujita, F.³ Watanabe, T.⁴ Tsukahara, K.⁵ Funahashi, Y.⁶ Fujita, M.⁷ Taguchi, T.⁸ Yoshino, H.⁹ Kitoh, K.¹⁰

180
- 0031860599
- (1998) Cancer Chemother. Pharmacol. , vol.42 , pp. 127
- Yamamoto, K.¹ Noda, K.² Yoshimura, A.³ Fukuoka, M.⁴ Furuse, K.⁵ Niitani, H.⁶

181
- 0001348505
- 390
- (1996) Proc. Am. Assoc. Cancer Res. , vol.37
- Owa, T.¹ Yoshino, H.² Okauchi, T.³ Okabe, T.⁴ Sugi, N.⁵ Ozawa, Y.⁶ Nagasu, T.⁷ Kitoh, K.⁸ Yoshimatsu, K.⁹

182
- 4243495920
- 391
- (1996) Proc. Am. Assoc. Cancer Res. , vol.37
- Sugi, N.¹ Ozawa, Y.² Watanabe, T.³ Nagasu, T.⁴ Owa, T.⁵ Koyanagi, N.⁶ Kitoh, K.⁷ Yoshimatsu, K.⁸

183
- 0000889198
- 391
- (1996) Proc. Am. Assoc. Cancer Res. , vol.37
- Watanabe, T.¹ Sugi, N.² Ozawa, Y.³ Owa, T.⁴ Nagasu, T.⁵ Koyanagi, N.⁶ Kitoh, K.⁷ Yoshimatsu, K.⁸

184
- 0000287735
- 609
- (2000) Proc. Am. Assoc. Cancer Res. , vol.41
- Dittrich, C.¹ Dumez, H.² Calvert, H.³ Hanauske, A.-R.⁴ Ravic, M.⁵ Faber, M.⁶ Van Houten, T.⁷ Wanders, J.⁸ Fumoleau, P.⁹

185
- 0000287738
- 609
- (2000) Proc. Am. Assoc. Cancer Res. , vol.41
- Droz, J.-P.¹ Roche, H.² Zanetta, S.³ Terret, C.⁴ Blay, J.Y.⁵ Dumortier, A.⁶ Kroon, K.⁷ Wanders, J.⁸ Ravic, M.⁹ Fumoleau, P.¹⁰

186
- 0000287732
- 609
- (2000) Proc. Am. Assoc. Cancer Res. , vol.41
- Punt, C.J.A.¹ Fumoleau, P.² Walle, B.V.D.³ Deporte-Fety, R.⁴ Bourcier, C.⁵ Faber, M.⁶ Ravic, M.⁷ Wagener, D.J.T.⁸

187
- 0000287741
- 611
- (2000) Proc. Am. Assoc. Cancer Res , vol.41
- Raymond, E.¹ Ten Bokkel Huinink, W.W.² Taieb, J.³ Beijnen, J.H.⁴ Mekhaldi, S.⁵ Kroon, K.⁶ Wanders, J.⁷ Ravic, M.⁸ Fumoleau, P.⁹ Ducreux, M.¹⁰ Escudier, B.¹¹ Armand, J.P.¹²

188
- 0031731295
- (1998) Exp. Opin. Ther. Patents , vol.8 , pp. 1599
- Traxler, P.¹

189
- 0032854118
- (1999) Curr. Med. Chem. , vol.6 , pp. 775
- Toledo, L.M.¹ Lydon, N.B.² Elbaum, D.³

190
- 0032830412
- (1999) Curr. Med. Chem. , vol.6 , pp. 825
- Bridges, A.J.¹

191
- 0032710852
- (1999) Curr. Opin. Biotechnol. , vol.10 , pp. 544
- Klohs, W.D.¹ Hamby, J.M.²

192
- 0034050902
- (2000) Nat. Genet. , vol.24 , pp. 227
- Ross, D.T.¹ Scherf, U.² Eisen, M.B.³ Perou, C.M.⁴ Rees, C.⁵ Spellman, P.⁶ Iyer, V.⁷ Jeffrey, S.S.⁸ Van de Rijn, M.⁹ Waltham, M.¹⁰ Pergamenschikov, A.¹¹ Lee, J.C.¹² Lashkari, D.¹³ Shalon, D.¹⁴ Myers, T.G.¹⁵ Weinstein, J.N.¹⁶ Botstein, D.¹⁷ Brown, P.O.¹⁸

193
- 0034088857
- (2000) Nat. Genet. , vol.24 , pp. 236
- Scherf, U.¹ Ross, D.T.² Waltham, M.³ Smith, L.H.⁴ Lee, J.K.⁵ Tanabe, L.⁶ Kohn, K.W.⁷ Reinhold, W.C.⁸ Myers, T.G.⁹ Andrews, D.T.¹⁰ Scudiero, D.A.¹¹ Eisen, M.B.¹² Sausville, E.A.¹³ Pommier, Y.¹⁴ Botstein, D.¹⁵ Brown, P.O.¹⁶ Weinstein, J.N.¹⁷

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.