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Volumn 91, Issue 7, 1998, Pages 2482-2490

Flavopiridol induces apoptosis of normal lymphoid cells, causes immunosuppression, and has potent antitumor activity in vivo against human leukemia and lymphoma xenografts

Author keywords

[No Author keywords available]

Indexed keywords

FLAVOPIRIDOL;

EID: 0032055497     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (240)

References (38)
  • 3
    • 0018396088 scopus 로고
    • The structure of rohitukine, the main alkaloid of Amoora rohituka (Syn. Aphanamixis polystachya) (Maliaceae)
    • Harmon AD, Weiss U, Silverton JV: The structure of rohitukine, the main alkaloid of Amoora rohituka (Syn. Aphanamixis polystachya) (Maliaceae). Tetrahedron Let 8:721, 1979
    • (1979) Tetrahedron Let , vol.8 , pp. 721
    • Harmon, A.D.1    Weiss, U.2    Silverton, J.V.3
  • 4
    • 0023924162 scopus 로고
    • An antiinflammatory cum immunomodulatory piperidinylbenzopyranone from Dysoxylum Binectariferum: Isolation, structure and total synthesis
    • Naik RG, Kattige SL, Bhat SB, Alreja B, de Souza NJ, Rupp RH: An antiinflammatory cum immunomodulatory piperidinylbenzopyranone from Dysoxylum Binectariferum: Isolation, structure and total synthesis. Tetrahedron 44:2081, 1988
    • (1988) Tetrahedron , vol.44 , pp. 2081
    • Naik, R.G.1    Kattige, S.L.2    Bhat, S.B.3    Alreja, B.4    De Souza, N.J.5    Rupp, R.H.6
  • 5
    • 0009475221 scopus 로고
    • Pharmacognosy of Aphanamixis polystachya stem bark
    • Sanyal M, Datta PC: Pharmacognosy of Aphanamixis polystachya stem bark. Q J Crude Drug Res 19:113, 1981
    • (1981) Q J Crude Drug Res , vol.19 , pp. 113
    • Sanyal, M.1    Datta, P.C.2
  • 6
    • 0000319960 scopus 로고
    • 8-C-methyl-quercetin-3-O-β-D-xylopyranoside, a new flavone glycoside from roots of Amoora rohituka
    • Jain A, Srivastava SK: 8-C-methyl-quercetin-3-O-β-D-xylopyranoside, a new flavone glycoside from roots of Amoora rohituka. J Nat Prod 48:299, 1985
    • (1985) J Nat Prod , vol.48 , pp. 299
    • Jain, A.1    Srivastava, S.K.2
  • 8
    • 0027083108 scopus 로고
    • Activation of human cyclin-dependent kinases in vitro
    • Desai D, Gu Y, Morgan DO: Activation of human cyclin-dependent kinases in vitro. Mol Biol Cell 3:571, 1992
    • (1992) Mol Biol Cell , vol.3 , pp. 571
    • Desai, D.1    Gu, Y.2    Morgan, D.O.3
  • 9
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO: Principles of CDK regulation. Nature 374:131, 1995
    • (1995) Nature , vol.374 , pp. 131
    • Morgan, D.O.1
  • 12
    • 0029665778 scopus 로고    scopus 로고
    • Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinases (CDK) 2 and CDK4 in human breast carcinoma cells
    • Carlson BA, Duba MM, Sausville EA, Brizuela L, Worland PJ: Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinases (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Res 56:2973, 1996
    • (1996) Cancer Res , vol.56 , pp. 2973
    • Carlson, B.A.1    Duba, M.M.2    Sausville, E.A.3    Brizuela, L.4    Worland, P.J.5
  • 16
    • 0345398627 scopus 로고    scopus 로고
    • A phase I trial of flavopiridol (FLA), a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms
    • abstr 793
    • Senderowicz AM, Headlee D, Stinson S, Lush RM, Figg WD, Pluda J, Sausville EA: A phase I trial of flavopiridol (FLA), a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms. Proc ASCO 16:226, 1997 (abstr 793)
    • (1997) Proc ASCO , vol.16 , pp. 226
    • Senderowicz, A.M.1    Headlee, D.2    Stinson, S.3    Lush, R.M.4    Figg, W.D.5    Pluda, J.6    Sausville, E.A.7
  • 19
    • 0029925857 scopus 로고    scopus 로고
    • Two serologic markers to monitor the engraftment, growth and treatment response of human leukemias in severe combined immunodeficient mice
    • Arguello F, Sterry JA, Zhao YZ, Alexander MRA, Shoemaker RH, Cohen HJ: Two serologic markers to monitor the engraftment, growth and treatment response of human leukemias in severe combined immunodeficient mice. Blood 87:4325, 1996
    • (1996) Blood , vol.87 , pp. 4325
    • Arguello, F.1    Sterry, J.A.2    Zhao, Y.Z.3    Alexander, M.R.A.4    Shoemaker, R.H.5    Cohen, H.J.6
  • 22
    • 0025748682 scopus 로고
    • An improved colorimetric assay for tumor necrosis factor using WEHI 164 cell cultures on novel microtiter plates
    • Morgan CD, Mills K, Lefkowitz DL, Lefkowitz SS: An improved colorimetric assay for tumor necrosis factor using WEHI 164 cell cultures on novel microtiter plates. J Immunol Methods 145:259, 1991
    • (1991) J Immunol Methods , vol.145 , pp. 259
    • Morgan, C.D.1    Mills, K.2    Lefkowitz, D.L.3    Lefkowitz, S.S.4
  • 23
    • 0029948611 scopus 로고    scopus 로고
    • Bcl-2 inhibits hydrogen peroxide-induced ER Ca2+ pool depletion
    • Distelhorst CK, Lam M, McCormick TS: Bcl-2 inhibits hydrogen peroxide-induced ER Ca2+ pool depletion. Oncogene 12:2051, 1996
    • (1996) Oncogene , vol.12 , pp. 2051
    • Distelhorst, C.K.1    Lam, M.2    McCormick, T.S.3
  • 24
    • 0021965803 scopus 로고
    • Graft-versus-host-disease-like histopathologic findings in pre-bone-marrow transplantation biopsies of patients with severe T-cell deficiency
    • Snover DC, Filipovich AH, Ramsay NK, Weisdorf SA, Kersey JH: Graft-versus-host-disease-like histopathologic findings in pre-bone-marrow transplantation biopsies of patients with severe T-cell deficiency. Transplantation 39:95, 1985
    • (1985) Transplantation , vol.39 , pp. 95
    • Snover, D.C.1    Filipovich, A.H.2    Ramsay, N.K.3    Weisdorf, S.A.4    Kersey, J.H.5
  • 25
    • 0025731380 scopus 로고
    • Small intestinal lesion resembling graft-vs-host disease: A case report in immunodeficiency and review of the literature
    • Lee EY, Clouse RE, Aliperti G, DeSchryver-Kacskemeti K: Small intestinal lesion resembling graft-vs-host disease: A case report in immunodeficiency and review of the literature. Arch Pathol Lab Med 115:529, 1991
    • (1991) Arch Pathol Lab Med , vol.115 , pp. 529
    • Lee, E.Y.1    Clouse, R.E.2    Aliperti, G.3    DeSchryver-Kacskemeti, K.4
  • 28
    • 0029075332 scopus 로고
    • Quercetin inhibits the growth of leukemic progenitors and induces the expression of transforming growth factor-β1 in these cells
    • Larocca LM, Teofili L, Sica S, Piantelli M, Maggiano N, Leone G, Ranelletti FO: Quercetin inhibits the growth of leukemic progenitors and induces the expression of transforming growth factor-β1 in these cells. Blood 85:3654, 1995
    • (1995) Blood , vol.85 , pp. 3654
    • Larocca, L.M.1    Teofili, L.2    Sica, S.3    Piantelli, M.4    Maggiano, N.5    Leone, G.6    Ranelletti, F.O.7
  • 29
    • 0027089920 scopus 로고
    • Growth inhibitory effects of bioflavonoids and related compounds on human leukemic CEM-C1 and CEM-C7 cells
    • Post JFM, Varma RS: Growth inhibitory effects of bioflavonoids and related compounds on human leukemic CEM-C1 and CEM-C7 cells. Cancer Lett 67:207, 1992
    • (1992) Cancer Lett , vol.67 , pp. 207
    • Post, J.F.M.1    Varma, R.S.2
  • 31
    • 0027154218 scopus 로고
    • Preliminary assessment of luteolin as an affinity ligand for type II estrogen binding sites in rat uterine nuclear extracts
    • Markaverich BM, Gregory RR: Preliminary assessment of luteolin as an affinity ligand for type II estrogen binding sites in rat uterine nuclear extracts. Steroids 58:268, 1993
    • (1993) Steroids , vol.58 , pp. 268
    • Markaverich, B.M.1    Gregory, R.R.2
  • 32
    • 0024284750 scopus 로고
    • Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes
    • Jaxel C, Taudou G, Portemer C, Mirambeau G, Panijel J, Duguet M: Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes. Biochem 27:95, 1988
    • (1988) Biochem , vol.27 , pp. 95
    • Jaxel, C.1    Taudou, G.2    Portemer, C.3    Mirambeau, G.4    Panijel, J.5    Duguet, M.6
  • 34
    • 0027337210 scopus 로고
    • Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II
    • McCabe MJ, Orrenius S: Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II. Biochem Biophys Res Commun 194:944, 1993
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 944
    • McCabe, M.J.1    Orrenius, S.2
  • 35
    • 0029904810 scopus 로고    scopus 로고
    • Flavopiridol: A cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells
    • Bible KC, Kaufman SH: Flavopiridol: A cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells. Cancer Res 56:4856, 1996
    • (1996) Cancer Res , vol.56 , pp. 4856
    • Bible, K.C.1    Kaufman, S.H.2
  • 36
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH, Nabel GJ: Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science 275:523, 1997
    • (1997) Science , vol.275 , pp. 523
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 37
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer agents
    • Hickman JA: Apoptosis induced by anticancer agents. Cancer Metastasis Rev 11:121, 1992
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 121
    • Hickman, J.A.1
  • 38
    • 0030271304 scopus 로고    scopus 로고
    • Chemical inhibitors of cyclin-dependent kinases
    • Meijer L: Chemical inhibitors of cyclin-dependent kinases. Trends Cell Biol 6:393, 1996
    • (1996) Trends Cell Biol , vol.6 , pp. 393
    • Meijer, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.