Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 4, 1998, Pages 1369-1374

  Moasser, Mark M ^a   Sepp Lorenzino, Laura ^a   Kohl, Nancy E ^b   Oliff, Allen ^b   Balog, Aaron ^a   Su, Dai Shi ^a   Danishefsky, Samuel J ^a   Rosen, Neal ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DNA; DOXORUBICIN; ENZYME INHIBITOR; FLUOROURACIL; PACLITAXEL; PROTEIN FARNESYLTRANSFERASE INHIBITOR; TRITIUM; VINBLASTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL CYCLE; CELL GROWTH; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA CONTENT; DRUG POTENTIATION; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; MITOSIS; PRIORITY JOURNAL; TUMOR CELL CULTURE;

ALKYL AND ARYL TRANSFERASES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; DNA FRAGMENTATION; DRUG SYNERGISM; ENZYME INHIBITORS; EPOTHILONES; FARNESYLTRANSTRANSFERASE; HUMANS; METHIONINE; MITOSIS; PACLITAXEL; THIAZOLES; TUMOR CELLS, CULTURED;

ANIMALIA; MURINAE; TRITIUM;

EID: 0032539559     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.4.1369     Document Type: Article

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