A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 8, 1999, Pages 4592-4597

  Saito, Akiko ^a   Yamashita, Takashi ^a   Mariko, Yukiyasu ^a   Nosaka, Yasuhito ^a   Tsuchiya, Katsutoshi ^b   Ando, Tomoyuki ^b   Suzuki, Tsuneji ^b   Tsuruo, Takashi ^c   Nakanishi, Osamu ^a  

^a Mitsui Pharmaceuticals Inc   (Japan)

^b Performance Materials R and D Center   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZAMIDE DERIVATIVE; HISTONE DEACETYLASE; MS 27275; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SENSITIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZAMIDES; BUTYRATES; CELL CYCLE; CELL SURVIVAL; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; ENZYME INHIBITORS; FEMALE; FLUOROURACIL; GELSOLIN; HISTONE DEACETYLASES; HL-60 CELLS; HUMANS; HYDROXAMIC ACIDS; K562 CELLS; KB CELLS; MICE; MICE, NUDE; OVARIAN NEOPLASMS; PANCREATIC NEOPLASMS; PYRIDINES; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

MUS MUSCULUS;

EID: 0033551152     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.8.4592     Document Type: Article

References (53)

1. Inoue, A. & Fujimoto, D. (1970) Biochim. Biophys. Acta 220, 307-316.
2. Vidali, G., Boffa, L. C. & Allfrey, V. G. (1972) J. Biol. Chem. 247, 7365-7373.
3. Kikuchi, H. & Fujimoto, D. (1973) FEBS Lett. 29, 280-282.
4. Csordas, A. (1990) Biochem. J. 265, 23-38.
5. Allegra, P., Sterner, R., Clayton, D. F. & Allfrey, V. G. (1987) J. Mol. Biol. 196, 379-388.
6. Hebbes, T. R., Thorne, A. W. & Crane-Robinson, C. (1988) EMBO J. 7, 1395-1403.
7. Tazi, J. & Bard, A. (1990) Cell 60, 909-920.
8. Roth, S. Y. & Allis, C. D. (1996) Cell 87, 5-8.
9. Wade, P. A., Pruss, D. & Wolfe, A. P. (1997) Trends Biochem. Sci. 22, 128-132.
10. Pazin, M. J. & Kadonaga, J. T. (1997) Cell 89, 325-328.
11. Riggs, M. G., Whittaker, R. G., Neuman, J. R. & Ingram, V. M. (1977) Nature (London) 268, 462-464.
12. Cioe, L., McNab, A., Hubbell, H. R., Meo, P., Curtis, P. & Rovera, G. (1981) Cancer Res. 41, 237-243.
13. Hoessly, M. C., Rossi, R. M. & Fischkoff, S. A. (1989) Cancer Res. 49, 3594-3597.
14. Kim, Y. S., Tsao, D., Siddiqui, B., Whitehead, J. S., Arnstein, P., Bennet, J. & Hicks, J. (1980) Cancer 45, 1185-1192.
15. Tsao, D., Morita, A., Bella, A., Luu, P. & Kim, Y. S. (1982) Cancer Res. 42, 1052-1058.
16. Ryan, M. P., Borenfreund, E. & Higgins, P. J. (1987) J. Natl. Cancer Inst. 79, 555-567.
17. Graham, K. A. & Buick, R. N. (1988) J. Cell. Physiol. 136, 63-71.
18. Guilbaud, N. F., Gas, N., Dupont, M. A. & Valette, A. (1990) J. Cell. Physiol. 145, 162-172.
19. Ryan, M. P. & Higgins, P. J. (1988) J. Cell. Physiol. 137, 25-34.
20. Huang, M. E., Ye, Y. C., Chen, S. R., Chai, J. R., Lu, J. X., Zhoa, L., Gu, L. J. & Wang, Z. Y. (1988) Blood 72, 567-572.
21. Novogradsky, A., Dvir, A., Ravid, A., Shkolnik, T., Stenzel, K. H., Rubin, A. L. & Zaizov, R. (1983) Cancer 51, 9-14.
22. Miller, A. A., Kurschel, E., Osieka, R. & Schmidt, C. (1987) Eur. J. Cancer Clin. Oncol. 23, 1283-1287.
23. Pouillart, P., Cerutti, I., Ronco, G., Villa, P. & Chany, C. (1991) Int. J. Cancer 49, 89-95.
24. Planchon, P., Pouillart, P., Ronco, G., Villa, P. & Pieri, F. (1993) J. Pharm. Sci. 82, 1046-1048.
25. Rephaeli, A., Rabizadeh, E., Aviram, A., Shaklai, M., Ruse, M. & Nudelman, A. (1991) Int. J. Cancer 49, 66-72.
26. Yoshida, M., Kijima, M., Akita, M. & Beppu, T. (1990) J. Biol. Chem. 265, 17174-17179.
27. Kijima, M., Yoshida, M., Sugita, K., Horinouchi, S. & Beppu, T. (1993) J. Biol. Chem. 268, 22429-22435.
28. Kwon, H. J., Owa, T., Hassig, C. A., Shimada, J. & Schreiber, S. L. (1998) Proc. Natl. Acad. Sci. USA 95, 3356-3361.
29. Sato, W., Fukazawa, N., Nakanishi, O., Baba, M., Suzuki, T., Yano, O., Naito, M. & Tsuruo, T. (1995) Cancer Chemother. Pharmacol. 35, 271-277.
30. Baba, M., Nakanishi, O., Saito, A., Miyama, Y., Yano, O., Shimada, S., Fukazawa, N., Naito, M. & Tsuruo, T. (1995) Cancer Chemother. Pharmacol. 36, 361-367.
31. Nakanishi, O., Baba, M., Saito, A., Yamashita, T., Sato, W., Abe, H., Fukazawa, N., Suzuki, T., Sato, S., Naito, M., et al. (1997) Oncol. Res. 9, 61-69.
32. Suzuki, T., Ando, T., Tsuchiya, K., Nakanishi, O., Saito, A., Yamashita, T., Shiraishi, Y. & Tanaka, E. (1997) Eur. Patent 847992; (1998) Chem. Abstr. 29, 95402.
33. Nakano, K., Mizuno, T., Sowa, Y., Orita, T., Yoshino, T., Okuyama, Y., Fujita, T., Ohtani-Fujita, N., Matsuzawa, Y., Tokino, T., et al. (1997) J. Biol. Chem. 272, 22199-22206.
34. Siavoshian, S., Blottiere, H. M., Cherbut, C. & Galmiche, J. P. (1997) Biochem. Biophys. Res. Commun. 232, 169-172.
35. Higgins, P. J. & Ryan, M. P. (1991) Biochem. J. 279, 883-890.
36. Hoshikawa, Y., Kwon, H. J., Yoshida, M., Horinouchi, S. & Beppu, T. (1994) Exp. Cell Res. 214, 189-197.
37. Harper, J. W., Hannon, G. J., Zhang, H., Casso, D. & Elledge, S. J. (1993) Cell 75, 805-816.
38. Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R. & Beach, D. (1993) Nature (London) 366, 701-704.
39. Gu, Y., Turck, C. W. & Morgan, D. O. (1993) Nature (London) 366, 707-710.
40. Dulic, V., Kaufmann, W. K., Wilson, S. J., Tlsty, T. D., Lees, E., Harper, J. W., Elledge, S. J. & Reed, S. I. (1994) Cell 76, 1013-1023.
41. El-Diery, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E. & Vogelstein, B. (1993) Cell 75, 817-825.
42. Wolf, D. & Rotter, V. (1985) Proc. Natl. Acad. Sci. USA 82, 790-794.
43. O'Connor, P. M., Jackman, J., Bae, I., Myers, T. G., Fan, S., Mutoh, M., Scudiero, D. A., Monks, A., Sausville, E. A., Weinstein, J. N., et al. (1997) Cancer Res. 57, 4285-4300.
44. Brown, R., Clugston, C., Burns, P., Edlin, A., Vasey, P., Vojtesek, B. & Kaye, S. B. (1993) Int. J. Cancer 55, 678-684.
45. Ruggeri, B., Zhang, S., Caamano, J., DiRado, M., Flynn, S. D. & Klein Szanto, A. J. (1992) Oncogene 7, 1503-1511.
46. DeCaprio, J., Ludlow, J. W., Lynch, D., Furukawa, Y., Griffin, J., Piwnica-Worms, H., Huang, C. M. & Livingston, D. M. (1989) Cell 58, 1085-1095.
47. Buchkovich, K., Duffy, L. A. & Harlow, E. (1989) Cell 58, 1097-1105.
48. Chen, P. L., Scully, P., Shew, J. Y., Wang, J. Y. J. & Lee, W. H. (1989) Cell 58, 1193-1198.
49. Müllauer, L., Fujita, H., Ishizaki, A. & Kuzumaki, N. (1993) Oncogene 8, 2531-2536.
50. Tanaka, M., Müllauer, L., Ogiso, Y., Fujita, H., Moriya, S., Furuuchi, K., Harabayashi, T., Shinohara, N., Koyanagi, T. & Kuzumaki, N. (1995) Cancer Res. 55, 3228-3232.
51. Vogelstein, B., Fearson, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakamura, Y., White, R., Smits, A. M. M. & Bos, J. L. (1988) N. Engl. J. Med. 319, 525-532.
52. Vogelstein, B. & Kinzler, K. W. (1998) Cell 70, 523-526.
53. Somasdaram, K., Zhang, H., Zeng, Y.-X., Houvras, Y., Peng, Y., Zhang, H., Wu, G. S., Licht, J. D., Weber, B. L. (1997) Nature (London) 389, 187-190.