Polyubiquitination and proteasomal degradation of the p185(c-erbB-2) receptor protein-tyrosine kinase induced by geldanamycin

Journal of Biological Chemistry

Volumn 271, Issue 37, 1996, Pages 22796-22801

  Mimnaugh, Edward G ^a   Chavany, Christine ^a   Neckers, Len ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELDANAMYCIN; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; PROTEIN TYROSINE KINASE; UBIQUITIN;

ARTICLE; BREAST CARCINOMA; CANCER INHIBITION; CATALYSIS; ENZYME DEGRADATION; HALF LIFE TIME; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ACETYLCYSTEINE; BENZOQUINONES; BIOPOLYMERS; BREAST NEOPLASMS; CELL LINE; CYSTEINE ENDOPEPTIDASES; ENZYME INHIBITORS; FEMALE; HUMANS; LACTAMS, MACROCYCLIC; MOLECULAR WEIGHT; MULTIENZYME COMPLEXES; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; QUINONES; RECEPTOR, ERBB-2; RIFABUTIN; UBIQUITINS;

EID: 0029812759     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.37.22796     Document Type: Article

References (32)

1. Yamamoto, T., Ikawa, S., Akiyama, T., Semba, K., Nomure, N., Miyajima, N., Saito, T., and Toyoshima, K. (1986) Nature 319, 230-234
2. Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McGuire, W. L. (1987) Science 235, 177-182
3. Di Fiore, P. P., Pierce, J. H., Kraus, M. H., Segatto, O., King, C. R., and Aaronson, S. A. (1987) Science 237, 178-182
4. Miller, P., DiOrio, C., Moyer, M., Schnur, R. C., Druskin, A., Cullen, W., and Moyer, J. D. (1994) Cancer Res. 54, 2724-2730
5. Uehara, Y., Murakami, Y., Mizuno, S., and Kawai, S. (1988) Virology 164, 294-298
6. Whiteaell, L., Mimnaugh, E. G., DeCosta, B., Myers, C. E., and Neckers, L. M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8324-8328
7. Schulte, T. W., Blagosklonny, M. V., Ingui, C., and Neckers, L. (1995) J. Biol. Chem. 270, 24585-24588
8. Miller, F., Schnur, R. C., Barbacci, E., Moyer, M. P., and Moyer, J. D. (1994) Biochem. Biophys. Res. Commun. 201, 1313-1319
9. Chavany, C., Mimnaugh, E. G., Miller, P., Bitton, R., Nguyen, P., Trepel, J., Whitesell, L., Schnur, R., Moyer, J. D., and Neckers, L. (1996) J. Biol. Chem. 271, 4974-4977
10. Welch, W. J. (1992) Physiol. Rev. 72, 1063-1081
11. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
12. Laemmli, U. K. (1970) Nature 227, 680-685
13. Bobrow, M. N., Harris, T. D., Shaughnessy, K. J., and Litt, G. J. (1989) J. Immunol. Methods 125, 279-285
14. Ciechanover, A., Finley, D., and Varshavsky, A. (1984) J. Cell. Biochem. 24, 137-163
15. Ciechanover, A. (1994) Cell 79, 13-21
16. Guarino, L. A., Smith, G., and Dong, W. (1995) Cell 80, 301-309
17. Fenteany, G., Standaert, R. F., Lane, W. S., Choi, S., Corey, E. J., and Schreiber, S. L. (1995) Science 268, 726-731
18. Poole, B., and Ohkuma, S. (1981) J. Cell Biol. 90, 665-669
19. Tartakoff, A. M. (1983) Cell 32, 1026-1028
20. Uehara, Y., Murakami, Y., Sugimoto, Y., and Mizuno, S. (1989) Cancer Res. 49, 780-785
21. Murakami, Y., Mizuno, S., and Uehara, Y. (1994) Biochem. J. 301, 63-68
22. Sepp-Lorenzino, L., Ma, Z., Lebwohl, D. E., Vinitsky, A., and Rosen, N. (1995) J. Biol. Chem. 270, 16580-16587
23. Blagosklonny, M. V., Toretsky, J., and Neckers, L. (1995) Oncogene 11, 933-939
24. Pagano, M., Tam, S. W., Theodoras, A. M., Beer-Romero, Del Sal, G., Chau, V., Yew, P. R., Draetta, G. F., and Rolfe, M. (1995) Science 269, 682-685
25. Galcheva-Gargova, Z., Theroux, S. J., and Davis, R. J. (1995) Oncogene 11, 2649-2655
26. Fenteany, G., Standaert, R. F., Reichard, G. A., Corey, E. J., and Schreiber, S. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 3358-3362
27. Ward, C. L., Omura, S., and Kopito, R. R. (1995) Cell 83, 121-127
28. Palombella, V. J., Rando, O. J., Goldberg, A. L., and Maniatis, T. (1994) Cell 78, 773-785
29. Jensen, T. J., Loo, M. A., Pind, S., Williams, D. B., Goldberg, A. L., and Riordan, J. R. (1995) Cell 83, 129-135
30. Mori, S., Claesson-Welsh, L., Okuyama, Y., and Saito, Y. (1995) Biochem. Biophys. Res. Commun. 213, 32-39
31. Mori, S., Heldin, C.-H., and Claesson-Welsh, L. (1993) J. Biol. Chem. 288, 577-583
32. Mimnaugh, E. G., Worland, P. J., Whitesell, L., and Neckers, L. M. (1995) J. Biol. Chem. 270, 28654-28659