-
1
-
-
0033600240
-
Interaction of c-Abl and p73a and their collaboration to induce apoptosis
-
Agami, R., Blandino, G., Oren, M. and Shaul, Y. (1999). Interaction of c-Abl and p73a and their collaboration to induce apoptosis. Nature 399, 809-813
-
(1999)
Nature
, vol.399
, pp. 809-813
-
-
Agami, R.1
Blandino, G.2
Oren, M.3
Shaul, Y.4
-
2
-
-
0028980494
-
R. (1995). P53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
-
Agarwal, M. L., Agarwal, A., Taylor, W. R. and Stark, G. R. (1995). p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America 92, 8493-8497
-
Proceedings of the National Academy of Sciences of the United States of America
, vol.92
, pp. 8493-8497
-
-
Agarwal, M.L.1
Agarwal, A.2
Taylor, W.R.3
Stark, G.4
-
3
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxia-inducible factor la
-
An, W. G., Kanekal, M., Simon, M. C., Maltepe, E., Blagosklonny, M. V. and Neckers, L. M. (1998). Stabilization of wild-type p53 by hypoxia-inducible factor la. Nature 392, 405-408
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
4
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
-
Attardi, L. D., Lowe, S. W., Brugarolas, J. and Jacks, T. (1996). Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO Journal 15, 3693-3701
-
(1996)
EMBO Journal
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
5
-
-
0031587821
-
Recruitment of p3Q0/CBP in p53 dependent signal pathways
-
Avantaggiati, M. L., Ogryzko, V., Gardner, K., Giordano, A., Levine, A. J. and Kelly, K. (1997). Recruitment of p3Q0/CBP in p53 dependent signal pathways. Cell 89, 1175-1184
-
(1997)
Cell
, vol.89
, pp. 1175-1184
-
-
Avantaggiati, M.L.1
Ogryzko, V.2
Gardner, K.3
Giordano, A.4
Levine, A.J.5
Kelly, K.6
-
6
-
-
0025040233
-
Suppression of human colorectal carcinoma cell growth by wild-type p53
-
Baker, S. J., Markowitz, S., Fearon, E. R., Willson, J. K. V. and Vogelstein, B. (1990). Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249, 912-915
-
(1990)
Science
, vol.249
, pp. 912-915
-
-
Baker, S.J.1
Markowitz, S.2
Fearon, E.R.3
Willson, J.K.V.4
Vogelstein, B.5
-
7
-
-
0032508504
-
Enhanced phosphoiy-lation of p53 by ATM in response to DNA damage
-
Banin, S., Moyal, L., Khostravi, R., Shieh, S. -Y., Taya, Y., Anderson, C. W., Chessa, L., Smorodinsky, N. I., Frives, C., Shiloh, Y. and Ziv, Y. (1998). Enhanced phosphoiy-lation of p53 by ATM in response to DNA damage. Science 281, 1674-1677
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Khostravi, R.3
Shieh, S.-Y.4
Taya, Y.5
Erson, C.W.6
Chessa, L.7
Smorodinsky, N.I.8
Frives, C.9
Shiloh, Y.10
Ziv, Y.11
-
8
-
-
0027459198
-
Mdm2 expression is induced by wild type p53 activity
-
Barak, Y., Juven, T., Haffner, R. and Oren, M. (1993). Mdm2 expression is induced by wild type p53 activity. EMBO Journal 12, 461-468
-
(1993)
EMBO Journal
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
9
-
-
0027749169
-
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein
-
Bargonetti, J., Manfredi, J. J., Chen, X., Marshak, D. R. and Prives, C. (1993). A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes & Development 7, 2565-2574
-
(1993)
Genes & Development
, vol.7
, pp. 2565-2574
-
-
Bargonetti, J.1
Manfredi, J.J.2
Chen, X.3
Marshak, D.R.4
Prives, C.5
-
10
-
-
0029774760
-
Characterisation of human cyclin G1 and G2: DNA damage inducible genes
-
Bates, S., Rowan, S. and Vousden, K. H. (1996). Characterisation of human cyclin G1 and G2: DNA damage inducible genes. Oncogene 13, 1103-1109
-
(1996)
Oncogene
, vol.13
, pp. 1103-1109
-
-
Bates, S.1
Rowan, S.2
Vousden, K.H.3
-
11
-
-
0032504783
-
E2F-1 regulation of pl4AR,: Links pRB and p53
-
Bates, S., Phillips, A. C., Clark, P. A., Stott, F., Peters, G., Ludwig, R. L. and Vousden, K. H. (1998). E2F-1 regulation of pl4AR,: links pRB and p53. Nature 395, 124-125
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clark, P.A.3
Stott, F.4
Peters, G.5
Ludwig, R.L.6
Vousden, K.H.7
-
12
-
-
0020679049
-
Patient with chromosome 13 deletion: Evidence that the retinoblastoma gene is a recessive cancer gene
-
Benedict, W. F., Murphree, A. L., Banerjee, A., Spina, C. A., Sparkes, M. C. and Sparkes, R. S. (1983). Patient with chromosome 13 deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science 219, 973-975
-
(1983)
Science
, vol.219
, pp. 973-975
-
-
Benedict, W.F.1
Murphree, A.L.2
Banerjee, A.3
Spina, C.A.4
Sparkes, M.C.5
Sparkes, R.S.6
-
13
-
-
0032500793
-
Cell surface rafficking of Fas: A rapid mechanism of p53-mediated apoptosis
-
Bennett, M., Macdonald, K., Chan, S. -W., Luzio, J. P., Simari, R. and Weissberg, P. (1998). Cell surface rafficking of Fas: A rapid mechanism of p53-mediated apoptosis. Science 282, 290-293
-
(1998)
Science
, vol.282
, pp. 290-293
-
-
Bennett, M.1
Macdonald, K.2
Chan, S.-W.3
Luzio, J.P.4
Simari, R.5
Weissberg, P.6
-
14
-
-
0030778862
-
Amplification and overexpression of MDM2 in primary (De novo) glioblastomas
-
Biernat, W., Kleihues, P., Yonekawa, Y. and Ohgaki, H. (1997). Amplification and overexpression of MDM2 in primary (de novo) glioblastomas. Journal of Neuropathology and Experimental Neurology 56, 180-185
-
(1997)
Journal of Neuropathology and Experimental Neurology
, vol.56
, pp. 180-185
-
-
Biernat, W.1
Kleihues, P.2
Yonekawa, Y.3
Ohgaki, H.4
-
15
-
-
0029832231
-
In vitro evaluation of a p53-expressing adenovirus as an anticancer drug
-
Blagosklonny, M. V. and El-Deiry, W. S. (1996). In vitro evaluation of a p53-expressing adenovirus as an anticancer drug. International Journal of Cancer 67, 386-392
-
(1996)
International Journal of Cancer
, vol.67
, pp. 386-392
-
-
Blagosklonny, M.V.1
El-Deiry, W.S.2
-
16
-
-
0033522143
-
DNA damage induced p53 stabilization: No indication for an involvement of p53 phosphorylation
-
Blattner, C., Tobiasch, E., Lstfen, M., Rahmsdouf, H. J. and Herrlich, P. (1999). DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation. Oncogene 18, 1723-1732
-
(1999)
Oncogene
, vol.18
, pp. 1723-1732
-
-
Blattner, C.1
Tobiasch, E.2
Lstfen, M.3
Rahmsdouf, H.J.4
Herrlich, P.5
-
17
-
-
0027176479
-
R. (1993). P53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines
-
Brachman, D. G., Beckett, M., Graves, D., Haraf, D., Vokes, E. and Weichselbaum, R. R. (1993). p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Research 53, 3667-3669
-
Cancer Research
, vol.53
, pp. 3667-3669
-
-
Brachman, D.G.1
Beckett, M.2
Graves, D.3
Haraf, D.4
Vokes, E.5
Weichselbaum, R.6
-
18
-
-
0029669929
-
T ceils from bax aipha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53
-
Brady, H. J., Salomons, G. S., Bobelduk, R. C. and Burns, A. J. (1996). T ceils from bax aipha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53. EMBO Journal 15, 1221-1230
-
(1996)
EMBO Journal
, vol.15
, pp. 1221-1230
-
-
Brady, H.J.1
Salomons, G.S.2
Bobelduk, R.C.3
Burns, A.J.4
-
19
-
-
0029097759
-
-
Brugarolas, J., Chandrasekaran, C., Gordon, J. I., Beach, D., Jacks, T. and Hannon, G. J. (1995). Radiation-induced cell cycle arrest compromised by p2i deficiency Nature 377, 552-557
-
(1995)
Radiation-Induced Cell Cycle Arrest Compromised by P2i Deficiency Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
20
-
-
0030883593
-
Interaction of p53 with the human Rad51 protein
-
Buchhop, S., Gibson, M. K., Wang, X. W., Wagner, P., Sturzbecher, H. W. and Harris, C. C. (1997). Interaction of p53 with the human Rad51 protein. Nucleic Acids Research 25, 3868-3874
-
(1997)
Nucleic Acids Research
, vol.25
, pp. 3868-3874
-
-
Buchhop, S.1
Gibson, M.K.2
Wang, X.W.3
Wagner, P.4
Sturzbecher, H.W.5
Harris, C.C.6
-
21
-
-
0028864667
-
-
Buckbinder, L., Talbott, R., Velasco-Miguel, S., Takenaka, I., Faha, B., Seizinger, B. R. and Kley, N. (1995). Induction of the growth inhibitor IGF-binding protein 3 byp53 Nature 377, 646-649
-
(1995)
Induction of the Growth Inhibitor Igf-Binding Protein 3 Byp53 Nature
, vol.377
, pp. 646-649
-
-
Buckbinder, L.1
Talbott, R.2
Velasco-Miguel, S.3
Takenaka, I.4
Faha, B.5
Seizinger, B.R.6
Kley, N.7
-
22
-
-
0032553485
-
Requirement forp53 and p21 to sustain G2 arrest after DNA damage
-
Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W. and Vogelstein, B. (1998). Requirement forp53 and p21 to sustain G2 arrest after DNA damage. Science 282, 1497-1501
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
23
-
-
8044233696
-
P53 alterations are predictive of chemoresistance and agressiveness in ovarian carcinomas: A molecular and immunohistochemical study
-
Buttitta, F., Marchetti, A., Gadduci, A., Pellegrini, S., Morgantj, M., Carnicelli, V., Cosío, S., Gagetti, O., Genazzanui, A. R. and Bevilaqua, G. (1997). p53 alterations are predictive of chemoresistance and agressiveness in ovarian carcinomas: a molecular and immunohistochemical study. British Journal of Cancer 75, 230-235
-
(1997)
British Journal of Cancer
, vol.75
, pp. 230-235
-
-
Buttitta, F.1
Marchetti, A.2
Gadduci, A.3
Pellegrini, S.4
Morgantj, M.5
Carnicelli, V.6
Cosío, S.7
Gagetti, O.8
Genazzanui, A.R.9
Bevilaqua, G.10
-
24
-
-
0028070989
-
P53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
-
Caelles, C., Helmberg, A. and Karin, M. (1994). p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370, 220-223
-
(1994)
Nature
, vol.370
, pp. 220-223
-
-
Caelles, C.1
Helmberg, A.2
Karin, M.3
-
25
-
-
0028171182
-
The p53-dependent Gl cell cycle checkpoint pathway and ataxia-telangiectasia
-
Canman, C. E., Wolff, A. C., Chen, C. Y., Fornace, A. J., and Kastan, M. B. (1994). The p53-dependent Gl cell cycle checkpoint pathway and ataxia-telangiectasia. Cancer Research 54, 5054-5058
-
(1994)
Cancer Research
, vol.54
, pp. 5054-5058
-
-
Canman, C.E.1
Wolff, A.C.2
Chen, C.Y.3
Fornace, A.J.4
Kastan, M.B.5
-
26
-
-
0032508608
-
Activation of the ATM kinase by ionising radiation and phosphorylation of p53
-
Canman, C. E., Lim, D. S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B. and Sjuciano, D. D. (1998). Activation of the ATM kinase by ionising radiation and phosphorylation of p53. Science 281, 1677-1679
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Sjuciano, D.D.9
-
27
-
-
0026069474
-
Oncogenes and signal transduction
-
Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R. and Soltoff, S. (1991). Oncogenes and signal transduction. Cell 64, 281-302
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carpenter, C.3
Duckworth, B.4
Graziani, A.5
Kapeller, R.6
Soltoff, S.7
-
28
-
-
0020518746
-
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
-
Cavenee, W. K., Dryja, T. P., Phillips, R. A., Benedict, W. F., Godbout, R., Gallie, B. L., Murphree, A. L., Strong, L. C. and Sparkes, R. S. (1983). Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 305, 779-784
-
(1983)
Nature
, vol.305
, pp. 779-784
-
-
Cavenee, W.K.1
Dryja, T.P.2
Phillips, R.A.3
Benedict, W.F.4
Godbout, R.5
Gallie, B.L.6
Murphree, A.L.7
Strong, L.C.8
Sparkes, R.S.9
-
29
-
-
0027522235
-
Cooperative DNA binding of p53 with TFÍFD (TBP): A possible mechanism for transcriptional activation
-
Chen, X., Farmer, G., Zhu, H., Prywes, R. and Prives, C. (1993). Cooperative DNA binding of p53 with TFÍFD (TBP): a possible mechanism for transcriptional activation. Genes & Development 7, 1837-1849
-
(1993)
Genes & Development
, vol.7
, pp. 1837-1849
-
-
Chen, X.1
Farmer, G.2
Zhu, H.3
Prywes, R.4
Prives, C.5
-
30
-
-
0032478331
-
Stabilization and activation of p53 are regulated independently by different phosphorylation events
-
Chernov, M. V., Ramana, C. V., Adler, V. V. and Stark, G. R. (1998). Stabilization and activation of p53 are regulated independently by different phosphorylation events. Proceedings of the National Academy of Sciences of the United States of America 95, 2284-2289
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 2284-2289
-
-
Chernov, M.V.1
Ramana, C.V.2
Adler, V.V.3
Stark, G.R.4
-
31
-
-
0027983669
-
Crystal structure of a p53 tumour suppressor-DNA complex: Understanding tumourigenic mutations
-
Cho, Y., Gorina, S., Jeffrey, P. D. and Pavletich, N. P. (1994). Crystal structure of a p53 tumour suppressor-DNA complex: understanding tumourigenic mutations. Science 265, 346-355
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
32
-
-
0029929672
-
Hypersensitivity of human testicular tumours to etoposide-induced apoptosis is associated with functional p53 and a high bax:Bcl-2 ratio
-
Chresta, C. M., Masters, J. R. W. and Hickman, J. A. (1996). Hypersensitivity of human testicular tumours to etoposide-induced apoptosis is associated with functional p53 and a high bax:bcl-2 ratio. Cancer Research 56, 1834-1841
-
(1996)
Cancer Research
, vol.56
, pp. 1834-1841
-
-
Chresta, C.M.1
Masters, J.R.W.2
Hickman, J.A.3
-
33
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke, A. R., Purdie, C. A., Harrison, D. J., Morris, R. G., Bird, C. C., Hooper, M. L. and Wylue, A. H. (1993). Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362, 849-852
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wylue, A.H.7
-
34
-
-
0031008749
-
J. (1997). P53, mutation frequency and apoptosis in the murine small intestine
-
Clarke, A. R., Howard, L. A., Harrison, Dj. and Winton, D. J. (1997). p53, mutation frequency and apoptosis in the murine small intestine. Oncogene 14, 2015-2018
-
Oncogene
, vol.14
, pp. 2015-2018
-
-
Clarke, A.R.1
Howard, L.A.2
Harrison, D.J.3
Winton, D.4
-
35
-
-
0028131554
-
Transcriptional activation by p53 correlates with suppression of growth but not transformation
-
Crook, T., Marston, N. J., Sara, E. A. and Vousden, K. H. (1994). Transcriptional activation by p53 correlates with suppression of growth but not transformation. Cell 79, 817-827
-
(1994)
Cell
, vol.79
, pp. 817-827
-
-
Crook, T.1
Marston, N.J.2
Sara, E.A.3
Vousden, K.H.4
-
36
-
-
0028913739
-
A p53-dependent mouse spindle checkpoint
-
Cross, S. M., Sanchez, C. A., Morgan, C. A., Schimke, M. K., Ramel, S., Idzerda, R. L., Raskind, W. H. and Reid, B, J. (1995). A p53-dependent mouse spindle checkpoint. Science 267, 1353-1356
-
(1995)
Science
, vol.267
, pp. 1353-1356
-
-
Cross, S.M.1
Sanchez, C.A.2
Morgan, C.A.3
Schimke, M.K.4
Ramel, S.5
Idzerda, R.L.6
Raskind, W.H.7
Reid, B.8
-
37
-
-
0027251720
-
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
-
Debbas, M. and White, E. (1993). Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes & Development 7, 546-554
-
(1993)
Genes & Development
, vol.7
, pp. 546-554
-
-
Debbas, M.1
White, E.2
-
38
-
-
0032476743
-
Two new p73 splice variants g and d, with different transcriptional activity
-
Delaurenzini, V., Costanzo, A., Barcarou, D., Terrinoni, A., Falco, M., Annicchiarico-Petruzzelli, M., Levrero, M. and Melino, G. (1998). Two new p73 splice variants g and d, with different transcriptional activity. Journal of Experimental Medicine 188, 1763-1768
-
(1998)
Journal of Experimental Medicine
, vol.188
, pp. 1763-1768
-
-
Delaurenzini, V.1
Costanzo, A.2
Barcarou, D.3
Terrinoni, A.4
Falco, M.5
Annicchiarico-Petruzzelli, M.6
Levrero, M.7
Melino, G.8
-
39
-
-
0018743916
-
Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse
-
Deleo, A. B., Jay, G., Appella, E., Dubois, G. C., Law, L. W. and Old, L. J. (1979). Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse. Proceedings of the National Academy of Sciences of the United States of America 76, 2420-2424
-
(1979)
Proceedings of the National Academy of Sciences of the United States of America
, vol.76
, pp. 2420-2424
-
-
Deleo, A.B.1
Jay, G.2
Appella, E.3
Dubois, G.C.4
Law, L.W.5
Old, L.J.6
-
40
-
-
0028978183
-
Mice lacking p2i wafi/cipi underg0 normal development but are defective in G1 checkpoint control
-
Deng, C., Zhang, P., Harper, J. W., Elledge, Sj. and Leder, P. (1995). Mice lacking p2i wafi/cipi underg0 normal development but are defective in G1 checkpoint control. Cell 82, 675-684
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
41
-
-
0032146795
-
E1A signalling to p53 involves the p 19ARFtumor suppressor
-
De Stanchina, E., Mccurrach, M. E., Zindy, F., Sheih, S. -Y., Ferbeyre, G., Samuelson, A. V., Prives, C., Roussel, M. F., Sherr, C. J. and Lowe, S. W. (1998). E1A signalling to p53 involves the p 19ARFtumor suppressor. Genes Development 12, 2434-2442
-
(1998)
Genes Development
, vol.12
, pp. 2434-2442
-
-
De Stanchina, E.1
McCurrach, M.E.2
Zindy, F.3
Sheih, S.-Y.4
Ferbeyre, G.5
Samuelson, A.V.6
Prives, C.7
Roussel, M.F.8
Sherr, C.J.9
Lowe, S.W.10
-
42
-
-
0030929838
-
DNA replication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRB function
-
Dileonardo, A., Khan, S. H., Linke, S. P., Greco, V., Seidita, G. and Wahl, G. M. (1997). DNA replication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRB function. Cancer Research 57, 1013-1019
-
(1997)
Cancer Research
, vol.57
, pp. 1013-1019
-
-
Dileonardo, A.1
Khan, S.H.2
Linke, S.P.3
Greco, V.4
Seidita, G.5
Wahl, G.M.6
-
43
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer, D., Pati, S., Zambetti, G., Chu, S., Teresky, A. K., Moore, M., Finlay, C. and Levine, Aj. (1993). Gain of function mutations in p53. Nature Genetics 4, 42-46
-
(1993)
Nature Genetics
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Finlay, C.7
Levine, A.8
-
44
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower, L. A., Harvey, M., Slagle, B. L., Mcarthur, M. J., Montgomery, C. A., Butel, J. S. and Bradley, A. (1992). Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356, 215-221
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery, C.A.5
Butel, J.S.6
Bradley, A.7
-
45
-
-
0012999265
-
Molecular detection of deletions involving band 14q of chromosome 13 in retinoblastoma
-
Dryja, T. P., Rapaport, J. M., Joyce, J. M. and Petersen, R. A. (1986). Molecular detection of deletions involving band 14q of chromosome 13 in retinoblastoma. Proceedings of the National Academy of Sciences of the United States of America 83, 7391-7394
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, pp. 7391-7394
-
-
Dryja, T.P.1
Rapaport, J.M.2
Joyce, J.M.3
Petersen, R.A.4
-
46
-
-
0028220204
-
-
Duuc, V., Kaufmann, W. K., Wilson, S. J., Tlsty, T. D., Lees, E., Harper, J. W., Elledge, S. J. and Reed, S. L. (1994). p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest Cell 76, 1013-1023
-
(1994)
P53-Dependent Inhibition of Cyclin-Dependent Kinase Activities in Human Fibroblasts during Radiation-Induced G1 Arrest Cell
, vol.76
, pp. 1013-1023
-
-
Duuc, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.L.8
-
47
-
-
0026849821
-
Definition of a consensus binding site for p53
-
El-Deiry, W. S., Kern, S. E., Pietenpol, J. A., Klnzler, K. W. and Vogelstein, B. (1992). Definition of a consensus binding site for p53. Nature Genetics 1, 45-49
-
(1992)
Nature Genetics
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Klnzler, K.W.4
Vogelstein, B.5
-
48
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry, W. S., Torino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W. and Vogelstein, B. (1993). WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Torino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
49
-
-
0021675797
-
Participation of p53 cellular tumour antigen in transformation of normal embryonic cells
-
Eliyahu, D., Raz, A., Gruss, P., Givol, D. and Oren, M. (1984). Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. Nature 312, 646-649
-
(1984)
Nature
, vol.312
, pp. 646-649
-
-
Eliyahu, D.1
Raz, A.2
Gruss, P.3
Givol, D.4
Oren, M.5
-
50
-
-
0029022365
-
Involvement of an ICE-fike protease in Fasmediated apoptosis
-
Enari, M., Hug, H. and Nagata, S. (1995). Involvement of an ICE-fike protease in Fasmediated apoptosis. Nature 375, 78-81
-
(1995)
Nature
, vol.375
, pp. 78-81
-
-
Enari, M.1
Hug, H.2
Nagata, S.3
-
51
-
-
0028171454
-
P53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents
-
Fan, S., El-Deiry, W. S., Bae, I., Freeman, J., Jondle, D., Bhatia, K., Fornace, A. J., Magrath, I., Kohn, K. W. and O'Connor, P. M. (1994). p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. Cancer Research 54, 5824-5830
-
(1994)
Cancer Research
, vol.54
, pp. 5824-5830
-
-
Fan, S.1
El-Deiry, W.S.2
Bae, I.3
Freeman, J.4
Jondle, D.5
Bhatia, K.6
Fornace, A.J.7
Magrath, I.8
Kohn, K.W.9
O'connor, P.M.10
-
52
-
-
0028901034
-
Disruption of p53 function sensitises breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
Fan, S., Smith, M. L., Rivet, D. J., Duba, D., Zahn, Q., Kohn, K. W., Fornace, A. J. and O'Connor, P. M. (1995). Disruption of p53 function sensitises breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Research 55, 1649-1654
-
(1995)
Cancer Research
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet, D.J.3
Duba, D.4
Zahn, Q.5
Kohn, K.W.6
Fornace, A.J.7
O'connor, P.M.8
-
53
-
-
0025024469
-
Presence of a potent transcriptional activating sequence in the p53 protein
-
Fields, S. and Jang, S. K. (1990). Presence of a potent transcriptional activating sequence in the p53 protein. Science 249, 1046-1049
-
(1990)
Science
, vol.249
, pp. 1046-1049
-
-
Fields, S.1
Jang, S.K.2
-
54
-
-
0024382760
-
The p53 proto-oncogene can act as a suppressor of transformation
-
Finlay, C. A., Hinds, P. W. and Levine, A. J. (1989). The p53 proto-oncogene can act as a suppressor of transformation. Cell 57, 1083-1093
-
(1989)
Cell
, vol.57
, pp. 1083-1093
-
-
Finlay, C.A.1
Hinds, P.W.2
Levine, A.J.3
-
55
-
-
0030925222
-
Wipl, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
-
Fiscella, M., Zhang, H., Fan, S., Sakaguchi, K., Shen, S., Mercer, W. E., Vande Woude, G. F., O'Connor, P. M. and Appella, E. (1997). Wipl, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proceedings of the National Academy of Sciences of the United States of America 94, 6048-6053
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, pp. 6048-6053
-
-
Fiscella, M.1
Zhang, H.2
Fan, S.3
Sakaguchi, K.4
Shen, S.5
Mercer, W.E.6
Vande Woude, G.F.7
O'connor, P.M.8
Appella, E.9
-
56
-
-
0027500246
-
Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
-
Fritsche, M., Haessler, C. and Brandner, G. (1993). Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 8, 307-318
-
(1993)
Oncogene
, vol.8
, pp. 307-318
-
-
Fritsche, M.1
Haessler, C.2
Brandner, G.3
-
57
-
-
0032167915
-
MEKK/JNK signalling stabilizes and activates p53
-
Fuchs, S. Y., Alder, V., Pincus, M. and Ronai, Z. (1998). MEKK/JNK signalling stabilizes and activates p53. Proceedings of the National Academy of Sciences of the United States of America 95, 10541-10546
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America 95
, pp. 10541-10546
-
-
Fuchs, S.Y.1
Alder, V.2
Pincus, M.3
Ronai, Z.4
-
58
-
-
0028231586
-
Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild type p53 gene
-
Fujiwara, T., Grimm, E. A., Mukhophadhyay, T., Zhang, W. W., Owen-Schaub, L. B. and Roth, J. A. (1994). Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild type p53 gene. Cancer Research 54, 2287-2291
-
(1994)
Cancer Research
, vol.54
, pp. 2287-2291
-
-
Fujiwara, T.1
Grimm, E.A.2
Mukhophadhyay, T.3
Zhang, W.W.4
Owen-Schaub, L.B.5
Roth, J.A.6
-
59
-
-
0029881977
-
Abnormal centrosome amplification in the absence of p53
-
Fukasawa, K., Choi, T., Kuriyama, R., Rulong, S. and Vande Woude, G. F. (1996). Abnormal centrosome amplification in the absence of p53. Science 271, 1744-1747
-
(1996)
Science
, vol.271
, pp. 1744-1747
-
-
Fukasawa, K.1
Choi, T.2
Kuriyama, R.3
Rulong, S.4
Vande Woude, G.F.5
-
60
-
-
0026650531
-
A transcriptionally active DNA-binding site for human p53 protein complexes
-
Funk, W. D., Pak, D. T., Karas, R. H., Wright, W. E. and Shay, J. W. (1992). A transcriptionally active DNA-binding site for human p53 protein complexes. Molecular and Cellular Biology 12, 2866-2871
-
(1992)
Molecular and Cellular Biology
, vol.12
, pp. 2866-2871
-
-
Funk, W.D.1
Pak, D.T.2
Karas, R.H.3
Wright, W.E.4
Shay, J.W.5
-
61
-
-
0029904706
-
Adenovirus-based transfer of wild-type p53 gene increases ovarian tumour radiosensitivity
-
Gallardo, D., Drazan, K. E. and Mcbride, W. H. (1996). Adenovirus-based transfer of wild-type p53 gene increases ovarian tumour radiosensitivity. Cancer Research 56, 4891-4893
-
(1996)
Cancer Research
, vol.56
, pp. 4891-4893
-
-
Gallardo, D.1
Drazan, K.E.2
McBride, W.H.3
-
62
-
-
0032518510
-
The candidate tumour suppressor p33INGl cooperates with p53 in cell growth control
-
Garkavtsev, I., Grigorian, I., Ossovskaya, V. S., Chernov, M. V., Chumakov, P. M. and Gudkov, A. V. (1998). The candidate tumour suppressor p33INGl cooperates with p53 in cell growth control. Nature 391, 295-298
-
(1998)
Nature
, vol.391
, pp. 295-298
-
-
Garkavtsev, I.1
Grigorian, I.2
Ossovskaya, V.S.3
Chernov, M.V.4
Chumakov, P.M.5
Gudkov, A.V.6
-
63
-
-
0025887476
-
Wild-type p53 can down-modulaie the activity of various promoters
-
Ginsberg, D., Mechta, F., Yaniv, M. and Oren, M. (1991). Wild-type p53 can down-modulaie the activity of various promoters. Proceedings of the National Academy of Sciences of the United States of America 88, 9979-9983
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, pp. 9979-9983
-
-
Ginsberg, D.1
Mechta, F.2
Yaniv, M.3
Oren, M.4
-
64
-
-
0033600234
-
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
Gong, J. G., Costanzo, A., Yang, H. -Q., Melino, G., Kaelin, W. G., Levrero, M. and Wang, J. Y. J. (1999). The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 399, 806-809
-
(1999)
Nature
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.-Q.3
Melino, G.4
Kaelin, W.G.5
Levrero, M.6
Wang, J.Y.J.7
-
65
-
-
0030575866
-
Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2
-
Gorina, S. and Pavletich, N. P. (1996). Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science 274, 1001-1005
-
(1996)
Science
, vol.274
, pp. 1001-1005
-
-
Gorina, S.1
Pavletich, N.P.2
-
66
-
-
0028294898
-
Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal
-
Gottlieb, E., Haffner R., Von-Ruden, T., Wagner, E. F. and Oren, M. (1994). Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO Journal 13, 1368-1374
-
(1994)
EMBO Journal
, vol.13
, pp. 1368-1374
-
-
Gottlieb, E.1
Haffner, R.2
Von-Ruden, T.3
Wagner, E.F.4
Oren, M.5
-
67
-
-
0028110809
-
Hypoxia induces the accumulation of p53 protein, but the activation of a G1 -phase checkpoint by low oxygen conditions is independent of p53 status
-
Graeber, T. G., Peterson, J. F., Tsai, M., Fornace, A. J. and Giaccia, A. J. (1994). Hypoxia induces the accumulation of p53 protein, but the activation of a G1 -phase checkpoint by low oxygen conditions is independent of p53 status. Molecular and Cellular Biology 14. 6264-6277
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 6264-6277
-
-
Graeber, T.G.1
Peterson, J.F.2
Tsai, M.3
Fornace, A.J.4
Giaccia, A.J.5
-
68
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer eitology and molecular pathogenesis
-
Greenblatt, M. S., Bennett, W. P., Hollstein, M. and Harris, C. C. (1994). Mutations in the p53 tumor suppressor gene: Clues to cancer eitology and molecular pathogenesis. Cancer Research 54, 4855-4878
-
(1994)
Cancer Research
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
69
-
-
0030797585
-
Activation of p53 sequence specific DNA binding by acetylation of the p53 C-terminal domain
-
Gu, W. and Roeder, R. G. (1997). Activation of p53 sequence specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90, 595-606
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
70
-
-
0030996361
-
Synergistic activation of transcription by CBP and p53
-
Gu, W., Shi, X. -L. and Roeder, R. G. (1997). Synergistic activation of transcription by CBP and p53. Nature 387, 819-822
-
(1997)
Nature
, vol.387
, pp. 819-822
-
-
Gu, W.1
Shi, X.-L.2
Roeder, R.G.3
-
71
-
-
0032574788
-
An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control
-
Gualberto, A., Aldape, K., Kozakiewicz, K. and Tlsty, T. D. (1998). An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. Proceedings of the National Academy of Sciences of the United States of America 95, 5166-5171
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 5166-5171
-
-
Gualberto, A.1
Aldape, K.2
Kozakiewicz, K.3
Tlsty, T.D.4
-
72
-
-
1842333306
-
P53 transactivation and protein accumulation are independently regulated by UV light in different phases of the cell cycle
-
Haapajarvi, T., Pitkanen, K., Tsubari, M. and Laiho, M. (1997). p53 transactivation and protein accumulation are independently regulated by UV light in different phases of the cell cycle. Molecular and Cellular Biology 17, 3074-3080
-
(1997)
Molecular and Cellular Biology
, vol.17
, pp. 3074-3080
-
-
Haapajarvi, T.1
Pitkanen, K.2
Tsubari, M.3
Laiho, M.4
-
73
-
-
0027528673
-
High levels of p53 protein in UV-irradiated normal human skin
-
Hall, P. A., Mckee, P. H., Menage, H. P., Dover, R. and Lane, D. P. (1993). High levels of p53 protein in UV-irradiated normal human skin. Oncogene 8, 203-207
-
(1993)
Oncogene
, vol.8
, pp. 203-207
-
-
Hall, P.A.1
McKee, P.H.2
Menage, H.P.3
Dover, R.4
Lane, D.P.5
-
74
-
-
0028596398
-
Transcription-coupled repair and human disease
-
Hanawalt, P. C. (1994). Transcription-coupled repair and human disease. Science 266, 1957-1958
-
(1994)
Science
, vol.266
, pp. 1957-1958
-
-
Hanawalt, P.C.1
-
75
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W. C., Counter, C. M., Lundberg, A. S., Beuersbergen, R. L., Brooks, M. W. and Weinberg, R. A. (1999). Creation of human tumour cells with defined genetic elements. Nature 400, 464-468
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beuersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
76
-
-
0029264061
-
The dominating effect of mutant p53
-
Hann, B. C. and Lane, D. P. (1995). The dominating effect of mutant p53. Nature Genetics 9, 221-222
-
(1995)
Nature Genetics
, vol.9
, pp. 221-222
-
-
Hann, B.C.1
Lane, D.P.2
-
77
-
-
0027496935
-
The p21 CDK-interacting protein Cip 1 is a potent inhibitor of G1 cyclin dependent kinases
-
Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K. and Elledge, S. J. (1993). The p21 CDK-interacting protein Cip 1 is a potent inhibitor of G1 cyclin dependent kinases. Cell 75, 805-816
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
78
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation deficient p53
-
Haupt, Y., Rowan, S., Shauuan, E., Vousden, K. H. and Oren, M. (1995). Induction of apoptosis in HeLa cells by transactivation deficient p53. Genes & Development 9, 2170-2183
-
(1995)
Genes & Development
, vol.9
, pp. 2170-2183
-
-
Haupt, Y.1
Rowan, S.2
Shauuan, E.3
Vousden, K.H.4
Oren, M.5
-
79
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., Maya, R., Kazaz, A. and Oren, M. (1997). Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
80
-
-
0030021996
-
Inactivation of p53 enhances sensitivity to multiple chemotherapeutic drugs
-
Hawkins, D. S., Demers, G. W. and Galloway, D. A. (1996). Inactivation of p53 enhances sensitivity to multiple chemotherapeutic drugs. Cancer Research 56, 892-898
-
(1996)
Cancer Research
, vol.56
, pp. 892-898
-
-
Hawkins, D.S.1
Demers, G.W.2
Galloway, D.A.3
-
81
-
-
0028171968
-
Mediation of c-myc induced apoptosis by p53
-
Hermekjng, H. and Elck, D. (1994). Mediation of c-myc induced apoptosis by p53. Science 265, 2091-2093
-
(1994)
Science
, vol.265
, pp. 2091-2093
-
-
Hermekjng, H.1
Elck, D.2
-
82
-
-
0031310665
-
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
-
Hermeking, H., Lengauer, C., Polyak, K., He, T. C., Zhang, L., Thiagaungam, S., Kinzler, K. W. and Vogelstein, B. (1997). 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Molecules and Cells 1, 3-11
-
(1997)
Molecules and Cells
, vol.1
, pp. 3-11
-
-
Hermeking, H.1
Lengauer, C.2
Polyak, K.3
He, T.C.4
Zhang, L.5
Thiagaungam, S.6
Kinzler, K.W.7
Vogelstein, B.8
-
83
-
-
0023239517
-
Functional inactivation of genes by dominant negative mutations
-
Herskowitz, I. (1987). Functional inactivation of genes by dominant negative mutations. Nature 329, 219-222
-
(1987)
Nature
, vol.329
, pp. 219-222
-
-
Herskowitz, I.1
-
84
-
-
0028860556
-
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis
-
Hiebert, S. W., Packham, G., Strom, D. K., Haffner, R., Oren, M., Zambeth, G. and Cleveland, J. L. (1995). E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis. Molecidar and Cellular Biology 15, 6864-6874
-
(1995)
Molecidar and Cellular Biology
, vol.15
, pp. 6864-6874
-
-
Hiebert, S.W.1
Packham, G.2
Strom, D.K.3
Haffner, R.4
Oren, M.5
Zambeth, G.6
Cleveland, J.L.7
-
85
-
-
0025894713
-
C. (1991). P53 mutations in human cancers
-
Hollstein, M., Sidransky, D., Vogelstein, B. and Harris, C. C. (1991). p53 mutations in human cancers. Science 253, 49-53
-
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.4
-
86
-
-
0032537851
-
E2F-1-induced p53-independent apoptosis in transgenic mice
-
Holmberg, C., Helsn, K., Sehested, M. and Karlstrom, O. (1998). E2F-1-induced p53-independent apoptosis in transgenic mice. Oncogene 17, 143-155
-
(1998)
Oncogene
, vol.17
, pp. 143-155
-
-
Holmberg, C.1
Helsn, K.2
Sehested, M.3
Karlstrom, O.4
-
87
-
-
0028519273
-
Ailosteric activation of latent p53 teramers
-
Hupp, T. R. and Lane, D. P. (1994). Ailosteric activation of latent p53 teramers. Current Biology 4, 865-875
-
(1994)
Current Biology
, vol.4
, pp. 865-875
-
-
Hupp, T.R.1
Lane, D.P.2
-
88
-
-
0027250493
-
Activation of the cryptic DNA binding function of mutant forms of p53
-
Hupp, T. R., Meek, D. W., Midgley, C. A. and Lane, D. P. (1993). Activation of the cryptic DNA binding function of mutant forms of p53. Nucleic Acids Research 21, 3167-3174
-
(1993)
Nucleic Acids Research
, vol.21
, pp. 3167-3174
-
-
Hupp, T.R.1
Meek, D.W.2
Midgley, C.A.3
Lane, D.P.4
-
89
-
-
0029055808
-
Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus
-
Jayaraman, L. and Prives, C. (1995). Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell 81, 1021-1029
-
(1995)
Cell
, vol.81
, pp. 1021-1029
-
-
Jayaraman, L.1
Prives, C.2
-
90
-
-
0030900605
-
-
Jayaraman, L., Murthy, K. J., Zhu, C., Curran, T., Xanthoudakis, S. and Prives, C. (1997). Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes & Development 11, 558-570
-
(1997)
Identification of Redox/Repair Protein Ref-1 as a Potent Activator of P53. Genes & Development
, vol.11
, pp. 558-570
-
-
Jayaraman, L.1
Murthy, K.J.2
Zhu, C.3
Curran, T.4
Xanthoudakis, S.5
Prives, C.6
-
91
-
-
0028952841
-
-
Jeffrey, P. D., Gorina, S. and Pavletich, N. P, (1995). Crystal structure of the tetramerization domain of the p53 tumour suppressor at 1. 7 angstroms. Science 267, 1498-1502
-
(1995)
Crystal Structure of the Tetramerization Domain of the P53 Tumour Suppressor at 1. 7 Angstroms. Science
, vol.267
, pp. 1498-1502
-
-
Jeffrey, P.D.1
Gorina, S.2
Pavletich, N.P.3
-
92
-
-
0033167979
-
DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage
-
Jimenez, G. S., Bryntesson, F., Torres-Arzayus, M. I., Priestley, A., Beeche, M., Saito, S., Sakaguchi, K., Appella, E., Jeggo, P. A., Taccioli, G. E., Wahl, G. M. and Hubank, M. (1999). DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage. Nature 400, 81-83
-
(1999)
Nature
, vol.400
, pp. 81-83
-
-
Jimenez, G.S.1
Bryntesson, F.2
Torres-Arzayus, M.I.3
Priestley, A.4
Beeche, M.5
Saito, S.6
Sakaguchi, K.7
Appella, E.8
Jeggo, P.A.9
Taccioli, G.E.10
Wahl, G.M.11
Hubank, M.12
-
93
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones, S. N., Roe, A. E., Donehower, L. A. and Bradley, A. (1995). Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 378, 206-208
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
94
-
-
0031564954
-
P73 is a human p53-related protein that can induce apoptosis
-
Jost, C. A., Martin, M. C. and Kaelin, W. G., (1997). p73 is a human p53-related protein that can induce apoptosis. Nature 389, 191-194
-
(1997)
Nature
, vol.389
, pp. 191-194
-
-
Jost, C.A.1
Martin, M.C.2
Kaelin, W.G.3
-
95
-
-
0027501841
-
Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene
-
Juven, T., Barak, Y., Zaubermann, A., George, D. and Oren, M. (1993). Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene. Oncogene 8, 3411-3416
-
(1993)
Oncogene
, vol.8
, pp. 3411-3416
-
-
Juven, T.1
Barak, Y.2
Zaubermann, A.3
George, D.4
Oren, M.5
-
96
-
-
0030812331
-
Monoallelically expressed gene related to p53 at lp36, a region frequently deleted in neuroblasoma and other human cancers
-
Kaghad, M., Bonnet, H., Yang, A., Creancier, L., Biscan, J. -C., Valent, A., Minty, A., Chalon, P., Lelias, J. -M., Dumont, X., Ferrara, P., Mckeon, F. and Caput, D, (1997). Monoallelically expressed gene related to p53 at lp36, a region frequently deleted in neuroblasoma and other human cancers. Cell 90, 809-819
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.-C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.-M.9
Dumont, X.10
Ferrara, P.11
McKeon, F.12
Caput, D.13
-
97
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product pl9AR
-
Kamijo, T., Zindy, F., Roussel, M. F., Quelle, D. E., Downing, J. R., Ashmun, R. A., Grosveld, G. and Sherr, C. J. (1997). Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product pl9AR,:. Cell 91, 649-659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
98
-
-
0032493350
-
Functional and physical interactions of the ARF tumour suppressor with p53 and Mdm2
-
Kamijo, T., Weber, J. D., Zambetti, G., Zindy, F., Roussel, M. F. and Sherr, C. J. (1998). Functional and physical interactions of the ARF tumour suppressor with p53 and Mdm2. Proceedings of the National Academy of Sciences of the United States of America 95, 8292-8297
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.F.5
Sherr, C.J.6
-
100
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan, M. B., Onyekwere, O., Sldransky, D., Vogelstein, B. and Craig, R. W. (1991). Participation of p53 protein in the cellular response to DNA damage. Cancer Research 51, 6304-6311
-
(1991)
Cancer Research
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sldransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
101
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan, M. B., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B. and Fornace, A. J.,. (1992). A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71, 587-597
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace, A.J.9
-
102
-
-
0029875247
-
DNA damage and cell cycle checkpoints
-
Kaufmann, W. and Paules, R. S. (1996). DNA damage and cell cycle checkpoints. FASEB Journal 10, 238-247
-
(1996)
FASEB Journal
, vol.10
, pp. 238-247
-
-
Kaufmann, W.1
Paules, R.S.2
-
103
-
-
0025815451
-
Identification of p53 as a sequence-specific DNA-binding protein
-
Kern, S. E., Kinzler, K. W., Baker, S. J., Bruskin, A., Jarosz, D., Friedman, P., Prives, C. and Vogelstein, B. (1991). Identification of p53 as a sequence-specific DNA-binding protein. Science 252, 1708-1711
-
(1991)
Science
, vol.252
, pp. 1708-1711
-
-
Kern, S.E.1
Kinzler, K.W.2
Baker, S.J.3
Bruskin, A.4
Jarosz, D.5
Friedman, P.6
Prives, C.7
Vogelstein, B.8
-
104
-
-
0032005132
-
P53 and pRB prevent replication in response to microtubule inhibitors by mediating a reversible G1 arrest
-
Khan, S. H, and Wahl, G. M. (1998). p53 and pRB prevent replication in response to microtubule inhibitors by mediating a reversible G1 arrest. Cancer Research 58, 396-400
-
(1998)
Cancer Research
, vol.58
, pp. 396-400
-
-
Khan, S.H.1
Wahl, G.M.2
-
105
-
-
0027486024
-
Ionizing radiation and UV induction of p53 protein by different pathways in ataxia telangiectasia cells
-
Khanna, K. K. and Lavin, M. F. (1993). Ionizing radiation and UV induction of p53 protein by different pathways in ataxia telangiectasia cells. Oncogene 8, 3307-3312
-
(1993)
Oncogene
, vol.8
, pp. 3307-3312
-
-
Khanna, K.K.1
Lavin, M.F.2
-
106
-
-
0030610962
-
Roie for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis
-
Kharbanda, S., Pandey, P., Schofield, L., Israels, S., Roncinske, R., Yoshida, K., Bharti, A., Yuan, Z. M., Saxena, S., Weichselbaum, R., Naun, C. and Kufe, D (1997). Roie for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America 94, 6939-6942
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, pp. 6939-6942
-
-
Kharbanda, S.1
Pandey, P.2
Schofield, L.3
Israels, S.4
Roncinske, R.5
Yoshida, K.6
Bharti, A.7
Yuan, Z.M.8
Saxena, S.9
Weichselbaum, R.10
Naun, C.11
Kufe, D.12
-
107
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck, R. M., Bossy-Wetzel, E., Green, D. R. and Newmeyer, D. D. (1997). The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
108
-
-
0030670332
-
P53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase I and enhances the level of casein kinase I delta in response to topoisomerase directed drugs
-
Knippschild, U., Milne, D. M., Campbell, L. E., Demaggjo, A. J., Christenson, E., Hoekstra, M. F. and Meek, D. W. (1997). p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase I and enhances the level of casein kinase I delta in response to topoisomerase directed drugs. Oncogene 15, 1727-1736
-
(1997)
Oncogene
, vol.15
, pp. 1727-1736
-
-
Knippschild, U.1
Milne, D.M.2
Campbell, L.E.3
Demaggjo, A.J.4
Christenson, E.5
Hoekstra, M.F.6
Meek, D.W.7
-
110
-
-
0030724673
-
P53 is phosphorylated by CDK7-cyclin H in a p36MATl-dependent manner
-
Ko, L. J., Shieh, S. Y., Chen, X., Jayaraman, L., Tamai, K., Taya, Y., Prives, C. and Pan, Z. Q. (1997). p53 is phosphorylated by CDK7-cyclin H in a p36MATl-dependent manner. Molecular and Cellular Biology 17, 7220-7229
-
(1997)
Molecular and Cellular Biology
, vol.17
, pp. 7220-7229
-
-
Ko, L.J.1
Shieh, S.Y.2
Chen, X.3
Jayaraman, L.4
Tamai, K.5
Taya, Y.6
Prives, C.7
Pan, Z.Q.8
-
111
-
-
0031766420
-
Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastomas and cel! lines
-
Kovalev, S., Marchenko, N., Swendeman, S., Laquaglia, M. and Moll, U. M. (1998). Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastomas and cel! lines. Cell Growth & Differentiation 9, 897-903
-
(1998)
Cell Growth & Differentiation 9
, pp. 897-903
-
-
Kovalev, S.1
Marchenko, N.2
Swendeman, S.3
Laquaglia, M.4
Moll, U.M.5
-
112
-
-
0024268311
-
Oligomerization of the oncoprotein p53
-
Kraiss, S. A., Quaiser, A., Oren, M. and Montenarh, M. (1988). Oligomerization of the oncoprotein p53. Journal of Virology 62, 4737-4744
-
(1988)
Journal of Virology
, vol.62
, pp. 4737-4744
-
-
Kraiss, S.A.1
Quaiser, A.2
Oren, M.3
Montenarh, M.4
-
113
-
-
0026006392
-
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence for a double block to p34cdc2 kinase activation in vertebrates
-
Krek, W. and Nigg, E. A. (1991). Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates. EMBO Journal 10, 3331-3341
-
(1991)
EMBO Journal
, vol.10
, pp. 3331-3341
-
-
Krek, W.1
Nigg, E.A.2
-
114
-
-
0030965946
-
-
Kubbutat, M. H., Jones, S. N. and Vousden, K. H. (1997). Regulation of p53 stability by MdmZ Nature 387, 229-303
-
(1997)
Regulation of P53 Stability by Mdmz Nature
, vol.387
, pp. 229-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
116
-
-
0018348655
-
T antigen is bound to a host protein in SV40-transformed cells
-
Lane, D. and Crawford, L. V. (1979). T antigen is bound to a host protein in SV40-transformed cells. Nature 278, 261-263
-
(1979)
Nature
, vol.278
, pp. 261-263
-
-
Lane, D.1
Crawford, L.V.2
-
117
-
-
0031931414
-
Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
-
Lanni, J. S. and Jacks, T. (1998). Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Molecular and Cellular Biology 18, 1055-1064
-
(1998)
Molecular and Cellular Biology
, vol.18
, pp. 1055-1064
-
-
Lanni, J.S.1
Jacks, T.2
-
119
-
-
0026687883
-
Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53
-
Lees-Miller, S. P., Sakaguchi, K., Ullrich, S. J., Appella, E. and Anderson, C. W. (1992). Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Molecular and Cellular Biology 12, 5041-5049
-
(1992)
Molecular and Cellular Biology
, vol.12
, pp. 5041-5049
-
-
Lees-Miller, S.P.1
Sakaguchi, K.2
Ullrich, S.J.3
Appella, E.4
Anderson, C.W.5
-
120
-
-
0025876591
-
The p53 tumour suppressor gene
-
Levine, A. J., Momand, J. and Finlay, C. A. (1991). The p53 tumour suppressor gene. Nature 351, 453-456
-
(1991)
Nature
, vol.351
, pp. 453-456
-
-
Levine, A.J.1
Momand, J.2
Finlay, C.A.3
-
121
-
-
0029964158
-
A reversible, p53 dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
-
Linke, S. P., Clarkin, K. C., Dileonardo, A., Tsou, A, and Wahl, G. M. (1996). A reversible, p53 dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes & Development 10, 934-947
-
(1996)
Genes & Development
, vol.10
, pp. 934-947
-
-
Linke, S.P.1
Clarkin, K.C.2
Dileonardo, A.3
Tsou, A.4
Wahl, G.M.5
-
122
-
-
0018760324
-
Characterization of a 54K dalton cellular SV40 tumor antigen present in S V40-transfonned cells and uninfected embryonal carcinoma cells
-
Llnzer, D. H. and Levine, A. J. (1979). Characterization of a 54K dalton cellular SV40 tumor antigen present in S V40-transfonned cells and uninfected embryonal carcinoma cells. Cell 17, 43-52
-
(1979)
Cell
, vol.17
, pp. 43-52
-
-
Llnzer, D.H.1
Levine, A.J.2
-
123
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu, X., Kim, C. N., Yang, J., Jemmerson, R. and Wang, X. (1996). Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86, 147-157
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
124
-
-
0027262606
-
Stabilization of the p53 tumour suppressor is induced by adenovirus 5 El A and accompanies apoptosis
-
Lowe, S. W. and Ruley, H. E. (1993). Stabilization of the p53 tumour suppressor is induced by adenovirus 5 El A and accompanies apoptosis. Genes & Development 7, 535-545
-
(1993)
Genes & Development
, vol.7
, pp. 535-545
-
-
Lowe, S.W.1
Ruley, H.E.2
-
125
-
-
0027319521
-
P53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A. and Jacks, T. (1993a). p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362, 847-849
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
126
-
-
0027451668
-
P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe, S. W., Ruley, H. E., Jacks, T. and Housman, D. E. (1993b). p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74, 957-967
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
128
-
-
0030610565
-
The CDK-cycH-p36 complex of transcription factor 11 H phosphorylates p53 and enhances its sequence-specific DNA binding activity in vitro
-
Lu, H., Fisher, R. P. and Levine, A. J. (1997). The CDK-cycH-p36 complex of transcription factor 11 H phosphorylates p53 and enhances its sequence-specific DNA binding activity in vitro. Molecular and Cellular Biology 17, 5923-5934
-
(1997)
Molecular and Cellular Biology
, vol.17
, pp. 5923-5934
-
-
Lu, H.1
Fisher, R.P.2
Levine, A.J.3
-
129
-
-
0032568633
-
Ultraviolet radiation but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 at serine-38
-
Lu, H., Taya, Y., Ikeda, M. and Levine, À. J. (1998). Ultraviolet radiation but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 at serine-38. Proceedings of the National Academy of Sciences of the United States of America 95, 6399-6402
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 6399-6402
-
-
Lu, H.1
Taya, Y.2
Ikeda, M.3
Levine, À.J.4
-
130
-
-
0029910628
-
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
-
Macleod, K. F., Hu, Y. and Jacks, T. (1996). Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO Journal 15, 6178-6188
-
(1996)
EMBO Journal
, vol.15
, pp. 6178-6188
-
-
Macleod, K.F.1
Hu, Y.2
Jacks, T.3
-
131
-
-
0032143910
-
Genomic organisation and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletion
-
Mai, M., Huang, H., Reed, C., Qian, C., Smith, J. S., Alderete, B., Jenkins, R., Smith, D. L. and Liu, W. (1998a). Genomic organisation and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletion. Genomics 51, 359-363
-
(1998)
Genomics
, vol.51
, pp. 359-363
-
-
Mai, M.1
Huang, H.2
Reed, C.3
Qian, C.4
Smith, J.S.5
Alderete, B.6
Jenkins, R.7
Smith, D.L.8
Liu, W.9
-
132
-
-
0032100611
-
Activation of p73 silent allele in lung cancer
-
Mai, M., Yokomizo, A., Qian, C., Yang, P., Tindall, D. J., Smith, D. L. and Liu, W. (1998b). Activation of p73 silent allele in lung cancer. Cancer Research 58, 2347-2349
-
(1998)
Cancer Research
, vol.58
, pp. 2347-2349
-
-
Mai, M.1
Yokomizo, A.2
Qian, C.3
Yang, P.4
Tindall, D.J.5
Smith, D.L.6
Liu, W.7
-
133
-
-
0028896811
-
Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells
-
Maity, A., Mckenna, W. G. and Muschel, R. J. (1995). Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells. EMBO Journal 14, 603-609
-
(1995)
EMBO Journal
, vol.14
, pp. 603-609
-
-
Maity, A.1
McKenna, W.G.2
Muschel, R.J.3
-
134
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin, D., Li, F. P., Strong, L. C., Fraumeni, J. F., Nelson, C. E., Kim, D. H., Kassel, J., Gryka, M. A., Bischoff, F. Z., Tainsky, M. A. and Friend, S. H, (1990). Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250, 1233-1238
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni, J.F.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
Friend, S.H.11
-
135
-
-
0021616838
-
UV radiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
-
Malzman, W. and Czyzyk, L. (1984). UV radiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Molecular and Cellular Biology 4, 1689-1694
-
(1984)
Molecular and Cellular Biology
, vol.4
, pp. 1689-1694
-
-
Malzman, W.1
Czyzyk, L.2
-
136
-
-
0031741138
-
Viral oncoproteins discriminate between p53 and the p53 homolog p73
-
Marin, M. C., Jost, C. A., Decaprio, J. A., Caput, D. and Kaelin, W. G., (1998). Viral oncoproteins discriminate between p53 and the p53 homolog p73. Molecular and Cellular Biology 18, 6316-6324
-
(1998)
Molecular and Cellular Biology
, vol.18
, pp. 6316-6324
-
-
Marin, M.C.1
Jost, C.A.2
Decaprio, J.A.3
Caput, D.4
Kaelin, W.G.5
-
137
-
-
0018832357
-
Association of a murine 53, 000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells
-
Mccormick, F. and Harlow, E. (1980). Association of a murine 53, 000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells. Journal of Virology 34, 213-224
-
(1980)
Journal of Virology
, vol.34
, pp. 213-224
-
-
McCormick, F.1
Harlow, E.2
-
138
-
-
0030722137
-
Hydrophobic stde-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain
-
Mccoy, M., Stavridi, E. S., Waterman, J. L., Opella, S. J. and Halazonetis, T. D. (1997). Hydrophobic stde-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain. EMBO Journal 16, 6230-6236
-
(1997)
EMBO Journal
, vol.16
, pp. 6230-6236
-
-
McCoy, M.1
Stavridi, E.S.2
Waterman, J.L.3
Opella, S.J.4
Halazonetis, T.D.5
-
139
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumour cell lines: Dependence on wild-type p53 for radiosensitivity
-
Mcilwrath, A. J., Vasey, P. A., Ross, G. M. and Brown, R. (1994). Cell cycle arrests and radiosensitivity of human tumour cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Research 54, 3718-3722
-
(1994)
Cancer Research
, vol.54
, pp. 3718-3722
-
-
McIlwrath, A.J.1
Vasey, P.A.2
Ross, G.M.3
Brown, R.4
-
140
-
-
0033081465
-
P53 DNA binding can be modulated by factors that alter the conformational equilibrium
-
Mclure, K. G. and Lee, P. W. (1999). p53 DNA binding can be modulated by factors that alter the conformational equilibrium. EM BO Journal 18, 763-770
-
(1999)
EM BO Journal
, vol.18
, pp. 763-770
-
-
McLure, K.G.1
Lee, P.W.2
-
141
-
-
0028960025
-
Somatic mutations in the BRCAi gene in sporadic ovarian tumours
-
Merajver, S. D., Pham, T. M., Caduff, R. F., Chen, M., Poy, E. L., Cooney, K. A., Weber, B. L., Collins, F. S., Johnston, C. and Frank, T. S, (1995). Somatic mutations in the BRCAi gene in sporadic ovarian tumours. Nature Genetics 9, 439-443
-
(1995)
Nature Genetics
, vol.9
, pp. 439-443
-
-
Merajver, S.D.1
Pham, T.M.2
Caduff, R.F.3
Chen, M.4
Poy, E.L.5
Cooney, K.A.6
Weber, B.L.7
Collins, F.S.8
Johnston, C.9
Frank, T.S.10
-
142
-
-
0033594491
-
P63 is a p53 homologue required for limb and epidennal morphogenesis
-
Mills, A. A., Zheng, B., Wang, X. -J., Vogel, H., Roop, D. R. and Bradley, A. (1999). p63 is a p53 homologue required for limb and epidennal morphogenesis. Nature 398, 708-713
-
(1999)
Nature
, vol.398
, pp. 708-713
-
-
Mills, A.A.1
Zheng, B.2
Wang, X.-J.3
Vogel, H.4
Roop, D.R.5
Bradley, A.6
-
143
-
-
0028966941
-
P53 is phosphory-lated in vitro and in vivo by an ultraviolet radiation induced protein kinase characteristic of the c-jun kinase, JNK1
-
Milne, D. M., Campbell, L. E., Campbell, D. G. and Meek, D. W. (1995). p53 is phosphory-lated in vitro and in vivo by an ultraviolet radiation induced protein kinase characteristic of the c-jun kinase, JNK1. Journal of Biological Chemistry 270, 5511-5518
-
Journal of Biological Chemistry
, vol.270
, pp. 5511-5518
-
-
Milne, D.M.1
Campbell, L.E.2
Campbell, D.G.3
Meek, D.W.4
-
144
-
-
0026060757
-
Tumor suppressor p53: Analysis of wildtype and mutant p53 complexes
-
Milner, J., Metcalf, E. A. and Cook, A. C. (1991). Tumor suppressor p53: analysis of wildtype and mutant p53 complexes. Molecular and Cellular Biology 11, 12-19
-
(1991)
Molecular and Cellular Biology
, vol.11
, pp. 12-19
-
-
Milner, J.1
Metcalf, E.A.2
Cook, A.C.3
-
145
-
-
0028883179
-
Tumour suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita, T. and Reed, J. C. (1995). Tumour suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
146
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
Miyashita, T., Krajewski, S., Krajewska, M., Wang, H. G., Lin, H. K., Liebermann, D. A., Hoffman, B. and Reed, J. C. (1994). Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9, 1799-1805
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
-
147
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand, J., Zambetti, G. P., Olson, D. C., George, D. and Levine, A. J. (1992). The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69, 1237-1245
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
148
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes DeOcaLuna, R., Wagner, D. S, and Lozano, G. (1995). Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 378, 203-206
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
Montes Deocaluna, R.1
Wagner, D.S.2
Lozano, G.3
-
149
-
-
0030880746
-
Cellular adhesion regulated p53 protein levels in primary human keratinocytes
-
Nigro, J. M., Aldape, S. M., Hess, S. M. and Tlsty, T. D. (1997). Cellular adhesion regulated p53 protein levels in primary human keratinocytes. Cancer Research 57, 3635-3639
-
(1997)
Cancer Research
, vol.57
, pp. 3635-3639
-
-
Nigro, J.M.1
Aldape, S.M.2
Hess, S.M.3
Tlsty, T.D.4
-
150
-
-
0032053793
-
Search for mutations and examination of allelic expression imbalance of the p73 gene at 1 p36. 33 in human lung cancers
-
Nomoto, S., Haruki, K, Kondo, M., Konishi, H., Takahashi, T., Takahashi, T. and Taka-Hashi, T. (1998). Search for mutations and examination of allelic expression imbalance of the p73 gene at 1 p36. 33 in human lung cancers. Cancer Research 58, 1380-1383
-
(1998)
Cancer Research
, vol.58
, pp. 1380-1383
-
-
Nomoto, S.1
Haruki, K.2
Kondo, M.3
Konishi, H.4
Takahashi, T.5
Takahashi, T.6
Taka-Hashi, T.7
-
151
-
-
0344389027
-
Caspases: The proteases of the apoptotic pathway
-
Nunez, G., Benedict, M. A., Hu, Y. and Inohara, N. (1998). Caspases: the proteases of the apoptotic pathway. Oncogene 17, 3237-3245
-
(1998)
Oncogene
, vol.17
, pp. 3237-3245
-
-
Nunez, G.1
Benedict, M.A.2
Hu, Y.3
Inohara, N.4
-
152
-
-
0027421045
-
Role of die p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma ceil lines
-
O'Connor, P. M., Jackman, J., Jondle, D., Bhatia, K., Magrath, F. and Kohn, K. W. (1993). Role of die p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma ceil lines. Cancer Research 53, 4776-4780
-
(1993)
Cancer Research
, vol.53
, pp. 4776-4780
-
-
O'connor, P.M.1
Jackman, J.2
Jondle, D.3
Bhatia, K.4
Magrath, F.5
Kohn, K.W.6
-
153
-
-
0027944251
-
Cyclin G is a transcriptional target of the p53 tumor suppressor protein
-
Okamoto, K. and Beach, D. (1994). Cyclin G is a transcriptional target of the p53 tumor suppressor protein. EMBO Journal 13, 4816-4822
-
(1994)
EMBO Journal
, vol.13
, pp. 4816-4822
-
-
Okamoto, K.1
Beach, D.2
-
154
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L. and Vogelstein, B. (1992). Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358, 80-83
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
155
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homoiog, Bax, that accelerates programmed cell death
-
Oltvai, Z. N., Milliman, C. L. and Korsmeyer, S. J. (1993). Bcl-2 heterodimerizes in vivo with a conserved homoiog, Bax, that accelerates programmed cell death. Cell 74, 609-619
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
156
-
-
0025632878
-
A potential transcriptional activation element in the p53 protein
-
O'Rourke, R. W., Miller, C. W., Kato, J. -G., Simon, K. J., Chen, D. L., Dang, C. V. and Koeffler, H. P. (1990). A potential transcriptional activation element in the p53 protein. Oncogene 5, 1829-1832
-
(1990)
Oncogene
, vol.5
, pp. 1829-1832
-
-
O'rourke, R.W.1
Miller, C.W.2
Kato, J.-G.3
Simon, K.J.4
Chen, D.L.5
Dang, C.V.6
Koeffler, H.P.7
-
157
-
-
0031852337
-
Cloning and functional analysis of human p51, which structually and functionally resembles p53
-
Osada, M., Ohba, M., Kawahara, C., Ishioka, C., Kanamaru, R., Katoh, I., Ikawa, Y., Nimura, Y., Nakagawara, A., Obinata, M. and Ikawa, S. (1998). Cloning and functional analysis of human p51, which structually and functionally resembles p53. Nature Medicine 4, 839-843
-
(1998)
Nature Medicine
, vol.4
, pp. 839-843
-
-
Osada, M.1
Ohba, M.2
Kawahara, C.3
Ishioka, C.4
Kanamaru, R.5
Katoh, I.6
Ikawa, Y.7
Nimura, Y.8
Nakagawara, A.9
Obinata, M.10
Ikawa, S.11
-
158
-
-
0029003501
-
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-I expression
-
Owen-Schaub, L. B., Zhang, W., Cusack, J. C., Angelo, L. S., Santee, S. M., Fujiwara, T., Roth, J. A., Deisseroth, A. B., Zhang, W. W., Kruzel, E. and Radinsky, R. (1995). Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-I expression. Molecular and Cellular Biology 15, 3032-3040
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 3032-3040
-
-
Owen-Schaub, L.B.1
Zhang, W.2
Cusack, J.C.3
Angelo, L.S.4
Santee, S.M.5
Fujiwara, T.6
Roth, J.A.7
Deisseroth, A.B.8
Zhang, W.W.9
Kruzel, E.10
Radinsky, R.11
-
159
-
-
0027771333
-
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots
-
Pavletich, N. P., Chambers, K. A. and Pabo, C. O. (1993). The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots. Genes & Development 7, 2556-2564
-
(1993)
Genes & Development
, vol.7
, pp. 2556-2564
-
-
Pavletich, N.P.1
Chambers, K.A.2
Pabo, C.O.3
-
160
-
-
0029126566
-
The basic carboxy-termina! domain of human p53 is dispensable for both transcriptional regulation and inhibition of tumor cell growth
-
Pellegata, N. S., Cajot, J. F. and Stanbridge, E. J. (1995). The basic carboxy-termina! domain of human p53 is dispensable for both transcriptional regulation and inhibition of tumor cell growth. Oncogene 11, 337-349
-
(1995)
Oncogene
, vol.11
, pp. 337-349
-
-
Pellegata, N.S.1
Cajot, J.F.2
Stanbridge, E.J.3
-
161
-
-
0030611095
-
Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
-
Peng, C. Y., Graves, P. R., Ti-Ioma, R. S., Wu, Z., Shaw, A. S. and Piwnica-Worms, H. (1997). Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277, 1501-1505
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.Y.1
Graves, P.R.2
Ti-Ioma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
162
-
-
0028365987
-
Expression of the p53 tumour suppressor gene product is a determinant of chemosenskivity
-
Petty, R. D., Cree, I. A., Sutherland, L. A., Hunter, E. M., Lande, D. P., Preecb, P. E. and Andreottl, P. E. (1994). Expression of the p53 tumour suppressor gene product is a determinant of chemosenskivity. Biochemical and Biophysical Research Communications 199, 264-270
-
(1994)
Biochemical and Biophysical Research Communications
, vol.199
, pp. 264-270
-
-
Petty, R.D.1
Cree, I.A.2
Sutherland, L.A.3
Hunter, E.M.4
Lande, D.P.5
Preecb, P.E.6
Andreottl, P.E.7
-
163
-
-
0030739355
-
Induction of DNA synthesis and apoptosis are separable functions of E2F-1
-
Phillips, A. C., Bates, S., Ryan, K. M., Helin, K. and Vousden, K, H. (1997). Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes & Development 11, 1853-1863
-
(1997)
Genes & Development
, vol.11
, pp. 1853-1863
-
-
Phillips, A.C.1
Bates, S.2
Ryan, K.M.3
Helin, K.4
Vousden, K.5
-
164
-
-
0028209857
-
Sequence-specific transcriptional activation is essential for growth suppression by p53
-
Pihtbnpol, J. A., Tokino, T., Thiagalingam, S., El-Deiry, W. S., Klnzler, K. W. and Vogelstein, B. (1994). Sequence-specific transcriptional activation is essential for growth suppression by p53. Proceedings of the National Academy of Sciences of the United States of America 91, 1998-2002
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, pp. 1998-2002
-
-
Pihtbnpol, J.A.1
Tokino, T.2
Thiagalingam, S.3
El-Deiry, W.S.4
Klnzler, K.W.5
Vogelstein, B.6
-
165
-
-
0032549704
-
The Ink4a tuinour suppressor gene product, pl9ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz, J., Schreiber-Agus, N., Liegeois, N. J., Silverman, A., Alland, L., Chin, L., Potes, J., Chen, K., Orlow, I., Lee, H. -W., Cordon-Cardo, C. and Depinho, R. (1998). The Ink4a tuinour suppressor gene product, pl9ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92, 713-723
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.-W.10
Cordon-Cardo, C.11
Depinho, R.12
-
166
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell, S. M., Zilz, N., Beazer-Barclay, Y., Bryan, T. M., Hamilton, S. R., Thibodeau, S. N., Vogelstein, B. and Kïnzler K. W. (1992). APC mutations occur early during colorectal tumorigenesis. Nature 359, 235-237
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kïnzler, K.W.8
-
167
-
-
0029587551
-
Alternative reading frames of the INK4a tumour suppressor gene encode two unrelated proteins capable of inducing ceii cycle arrest
-
Quelle, D. E., Zîndy, F., Ashmun, R. A. and Sherr, C. J. (1995). Alternative reading frames of the INK4a tumour suppressor gene encode two unrelated proteins capable of inducing ceii cycle arrest. Cell 83, 993-1000
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zîndy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
168
-
-
0027158460
-
Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif
-
Ragimov, N., Krauskopf, A., Navot, N., Rotter, V., Oren, M. and Aloni, Y. (1993). Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif. Oncogene 8, 1183-1193
-
(1993)
Oncogene
, vol.8
, pp. 1183-1193
-
-
Ragimov, N.1
Krauskopf, A.2
Navot, N.3
Rotter, V.4
Oren, M.5
Aloni, Y.6
-
169
-
-
0032409781
-
Bci-2 family proteins
-
Reed, J. C. (1998). Bci-2 family proteins. Oncogene 17, 3225-3236
-
(1998)
Oncogene
, vol.17
, pp. 3225-3236
-
-
Reed, J.C.1
-
170
-
-
13344249778
-
A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma
-
Righetti, S. C., Della Torre, G., Pilotti, S., Menard, S., Ottone, F., Colnaghi, M. I., Plerotti, M. A., Lavarino, C., Cornarotti, M., Oriana, S., Boiim, S., Bresciani, G. L., Spatti, G. and Zunino, F. (1996). A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma. Cancer Research 56, 689-693
-
(1996)
Cancer Research
, vol.56
, pp. 689-693
-
-
Righetti, S.C.1
Della Torre, G.2
Pilotti, S.3
Menard, S.4
Ottone, F.5
Colnaghi, M.I.6
Plerotti, M.A.7
Lavarino, C.8
Cornarotti, M.9
Oriana, S.10
Boiim, S.11
Bresciani, G.L.12
Spatti, G.13
Zunino, F.14
-
171
-
-
0031771497
-
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA méthylation and down-regulated by wild-type p53
-
Robertson, K. D. and Jones, P. A. (1998). The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA méthylation and down-regulated by wild-type p53. Molecular and Cellular Biology 18, 6457-6473
-
(1998)
Molecular and Cellular Biology
, vol.18
, pp. 6457-6473
-
-
Robertson, K.D.1
Jones, P.A.2
-
172
-
-
0032518917
-
Nucleo-cytopiasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
-
Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T. and Levine, A. J. (1998). Nucleo-cytopiasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO Journal 17, 554-564
-
(1998)
EMBO Journal
, vol.17
, pp. 554-564
-
-
Roth, J.1
Dobbelstein, M.2
Freedman, D.A.3
Shenk, T.4
Levine, A.J.5
-
173
-
-
0029143395
-
Essential role for p53-mediated transcription in apoptosis but not growth suppression
-
Sabbatini, P., Lfn, J., Levine, A. J. and White, E. (1995). Essential role for p53-mediated transcription in apoptosis but not growth suppression. Genes & Development 9, 2184-2192
-
(1995)
Genes & Development
, vol.9
, pp. 2184-2192
-
-
Sabbatini, P.1
Lfn, J.2
Levine, A.J.3
White, E.4
-
174
-
-
0021780972
-
Genetic suppression of tumour formation. Adv
-
Sager, R. (1985). Genetic suppression of tumour formation. Adv. Cancer Research 44, 43-68
-
(1985)
Cancer Research
, vol.44
, pp. 43-68
-
-
Sager, R.1
-
175
-
-
0029007405
-
A subset of p53-deficient embryos exhibit exencephaly
-
Sah, V. P., Attardi, L. D., Mulligan, G. J., Williams, B. O., Bronson, R. T. and Jacks, T. (1995). A subset of p53-deficient embryos exhibit exencephaly. Nature Genetics 10, 175-180
-
(1995)
Nature Genetics
, vol.10
, pp. 175-180
-
-
Sah, V.P.1
Attardi, L.D.2
Mulligan, G.J.3
Williams, B.O.4
Bronson, R.T.5
Jacks, T.6
-
176
-
-
0030790778
-
Phosphorylation of serine 392 stabilizes the tetramer formation of tumour suppressor protein p53
-
Sakaguchi, K., Sakamoto, H., Lewis, M. S., Anderson, C. W., Erickson, J. W., Appella, E. and Xle, D. (1997). Phosphorylation of serine 392 stabilizes the tetramer formation of tumour suppressor protein p53. Biochemistry 36, 10117-10124
-
(1997)
Biochemistry
, vol.36
, pp. 10117-10124
-
-
Sakaguchi, K.1
Sakamoto, H.2
Lewis, M.S.3
Erson, C.W.4
Erickson, J.W.5
Appella, E.6
Xle, D.7
-
177
-
-
0032530486
-
DNA damage activated p53 through a phosphorylation-acétylation cascade
-
Sakaguchi, K., Herrera, J. E., Saito, S., Miki, T., Bustîn, M., Vasilev, A., Anderson, C. W. and Appella, E. (1998). DNA damage activated p53 through a phosphorylation-acétylation cascade. Genes & Development 12, 2831-2841
-
(1998)
Genes & Development
, vol.12
, pp. 2831-2841
-
-
Sakaguchi, K.1
Herrera, J.E.2
Saito, S.3
Miki, T.4
Bustîn, M.5
Vasilev, A.6
Erson, C.W.7
Appella, E.8
-
178
-
-
0031823480
-
Bcl-2 family proteins as ion-channels
-
Schendel, S. L., Montal, M. and Reed, J. C. (1998). Bcl-2 family proteins as ion-channels. Cell Death and Differentiation 5, 372-380
-
(1998)
Cell Death and Differentiation
, vol.5
, pp. 372-380
-
-
Schendel, S.L.1
Montal, M.2
Reed, J.C.3
-
179
-
-
0023899344
-
Characterization of the in vitro interaction between SV40 T antigen and p53: Mapping the p53 binding site
-
Schmieg, F. I. and Simmons, D. T. (1988). Characterization of the in vitro interaction between SV40 T antigen and p53: mapping the p53 binding site. Journal of Virology 164, 132-140
-
(1988)
Journal of Virology
, vol.164
, pp. 132-140
-
-
Schmieg, F.I.1
Simmons, D.T.2
-
180
-
-
0028238213
-
Immediate early up-regulation of bax expression by p53 but not TGF beta 1: A paradigm for distinct apoptotic pathways
-
Selvakumaran, M., Un, H. K., Miyashita, T., Wang, H. G., Krajewski, S., Reed, J. C., Hoffman, B. and LIEBERMANN, D. (1994). Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways. Oncogene 9, 1791-1798
-
(1994)
Oncogene
, vol.9
, pp. 1791-1798
-
-
Selvakumaran, M.1
Un, H.K.2
Miyashita, T.3
Wang, H.G.4
Krajewski, S.5
Reed, J.C.6
Hoffman, B.7
Liebermann, D.8
-
181
-
-
0025751550
-
Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
-
Sentman, C. L., Shutter, J. R., Hockenbery, D., Kanagawa, O. and Korsmeyer, S. J. (1991). Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67, 879-888
-
(1991)
Cell
, vol.67
, pp. 879-888
-
-
Sentman, C.L.1
Shutter, J.R.2
Hockenbery, D.3
Kanagawa, O.4
Korsmeyer, S.J.5
-
182
-
-
0029993450
-
-
Serrano, M., Lee, H. -W., Chin, L., Cordon-Cardo, C., Beach, D. and Depinho, R. A. (1996). Role of the INK4a locus in tumor suppression and ceil mortality. Cell 85, 27-37
-
-
-
Serrano, M.1
Lee, H.-W.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
Depinho, R.A.6
-
183
-
-
0030667702
-
-
Shieh, S. -Y., Ikeda, M., Taya, Y. and Prives, C. (1997). DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334
-
-
-
Shieh, S.-Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
184
-
-
0033519705
-
-
Shimizu, S., Narita, M. and Tsujimoto, Y. (1999). Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399, 483-487
-
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
185
-
-
0028868432
-
-
Shivakumar, C. V., Brown, D. R., Deb, S. and Deb, S. P. (1995). Wiid-type human p53 transactivates the human proliferating cell nuclear antigen promoter. Molecular and Cellular Biology 15, 6785-6793
-
-
-
Shivakumar, C.V.1
Brown, D.R.2
Deb, S.3
Deb, S.P.4
-
186
-
-
0030045087
-
Relationship between p53 status and radiosensitivity in human tumour cell lines
-
Siles, E., Villalobos, M., Valenzuela, M. T., Nunez, M. I., Gordon, A., Mcmillan, T. J., Pedraza, V. and Ruiz De Almodovar, J. M. (1996). Relationship between p53 status and radiosensitivity in human tumour cell lines. British Journal of Cancer 73, 581-588
-
(1996)
British Journal of Cancer
, vol.73
, pp. 581-588
-
-
Siles, E.1
Villalobos, M.2
Valenzuela, M.T.3
Nunez, M.I.4
Gordon, A.5
McMillan, T.J.6
Pedraza, V.7
Ruiz De Almodovar, J.M.8
-
187
-
-
0031435944
-
-
Silìciano, J. D., Canman, C. E., Taya, Y., Sakaguchi, K., Appella, E. and Kastan, M. B. (1997). DNA damage induces phosphorylation of the amino terminus of p53. Genes & Development 11, 3471-3481
-
-
-
Silìciano, J.D.1
Canman, C.E.2
Taya, Y.3
Sakaguchi, K.4
Appella, E.5
Kastan, M.B.6
-
188
-
-
0028569767
-
Interaction of the p53-reguiated protein Gadd45 with proliferating cell nuclear antigen
-
Smith, M. L., Chen, I. T., Zhan, Q., Bae, I., Chen, C. Y., Gilmer, T. M., Kastan, M. B., O'Connor, P. M. and Fornace, A. J. (1994). Interaction of the p53-reguiated protein Gadd45 with proliferating cell nuclear antigen. Science 266, 1376-1380
-
(1994)
Science
, vol.266
, pp. 1376-1380
-
-
Smith, M.L.1
Chen, I.T.2
Zhan, Q.3
Bae, I.4
Chen, C.Y.5
Gilmer, T.M.6
Kastan, M.B.7
O'connor, P.M.8
Fornace, A.J.9
-
189
-
-
0033515883
-
Apaf-1 andcaspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas, M. S., Alarcon, R. M., Yoshida, H., Giaccia, A. J., Hakem, R., Mak, T. W. and Lowb, S. W. (1999). Apaf-1 andcaspase-9 in p53-dependent apoptosis and tumor inhibition. Science 284, 156-159
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowb, S.W.7
-
190
-
-
0025648762
-
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
-
Srivastava, S., Zou, Z., Pirollo, K., Blaitner, W. and Chang, E. H. (1990). Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 348, 747-749
-
(1990)
Nature
, vol.348
, pp. 747-749
-
-
Srivastava, S.1
Zou, Z.2
Pirollo, K.3
Blaitner, W.4
Chang, E.H.5
-
191
-
-
0028813528
-
Evidence for a second cell cycle block at G2/M by p53
-
Stewart, N., Hicks, G. G., Paraskevas, F. and Mow At, M. (1995). Evidence for a second cell cycle block at G2/M by p53. Oncogene 10, 109-115
-
(1995)
Oncogene
, vol.10
, pp. 109-115
-
-
Stewart, N.1
Hicks, G.G.2
Paraskevas, F.3
Mow At, M.4
-
192
-
-
0032952584
-
A. (1999). P21Wafl/c'P inhibition of cyclin E/ Cdk2 activity prevents endoreduplication after mitotic spindle disruption
-
Stewart, Z. A., Leach, S. D. and Pietenpol, J. A. (1999). p21Wafl/c'P inhibition of cyclin E/ Cdk2 activity prevents endoreduplication after mitotic spindle disruption. Molecular and Cellular Biology 19, 205-215
-
Molecular and Cellular Biology
, vol.19
, pp. 205-215
-
-
Stewart, Z.A.1
Leach, S.D.2
Pietenpol, J.3
-
193
-
-
0033559256
-
A leucine-rich nuclear export signal in thep53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
-
Stommel, J. M., Marchenko, N. D., Jimenez, G. S., Moll, U. M., Hope, T. J. and Wahl, G. M. (1999). A leucine-rich nuclear export signal in thep53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO Journal 18, 1660-1672
-
(1999)
EMBO Journal
, vol.18
, pp. 1660-1672
-
-
Stommel, J.M.1
Marchenko, N.D.2
Jimenez, G.S.3
Moll, U.M.4
Hope, T.J.5
Wahl, G.M.6
-
194
-
-
0032169516
-
The alternative product from the human CDKN2A locus, pl4ARF, participates in a regulatory feedback loop with p53 and MDM2
-
Stott, F., Bates, S. A., James, M., Mcconnell, B. B., Starborg, M., Brookes, S., Palmero, I., Hara, E., Vousden, K. H. and Peters, G. (1998). The alternative product from the human CDKN2A locus, pl4ARF, participates in a regulatory feedback loop with p53 and MDM2. EMBO Journal 17, 5001-5014
-
(1998)
EMBO Journal
, vol.17
, pp. 5001-5014
-
-
Stott, F.1
Bates, S.A.2
James, M.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Hara, E.8
Vousden, K.H.9
Peters, G.10
-
195
-
-
0028054017
-
T-cell apoptosis detected in situ during positive and negative selection in the thymus
-
Surh, C. D. and Sprent, J. (1994). T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372, 100-103
-
(1994)
Nature
, vol.372
, pp. 100-103
-
-
Surh, C.D.1
Sprent, J.2
-
196
-
-
0032523842
-
Mutation, ailelotyping and transcription analyses of the p73 gene in prostatic carcinomas
-
Takahashi, H., Ichimiya, S., Nìmura, Y., Watanabe, M., Furusato, M., Wakui, S., Yatani, R., Aizawa, S. and Nakagawara, A. (1998). Mutation, ailelotyping and transcription analyses of the p73 gene in prostatic carcinomas. Cancer Research 58, 2076-2077
-
(1998)
Cancer Research
, vol.58
, pp. 2076-2077
-
-
Takahashi, H.1
Ichimiya, S.2
Nìmura, Y.3
Watanabe, M.4
Furusato, M.5
Wakui, S.6
Yatani, R.7
Aizawa, S.8
Nakagawara, A.9
-
197
-
-
0025980976
-
Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18
-
Tanaka, K., Oshimura, M., Kikuchi, R., Seki, M., Hayashi, T. and Miyaki, M. (1991). Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18. Nature 349, 340-342
-
(1991)
Nature
, vol.349
, pp. 340-342
-
-
Tanaka, K.1
Oshimura, M.2
Kikuchi, R.3
Seki, M.4
Hayashi, T.5
Miyaki, M.6
-
198
-
-
0028922929
-
P53 transcriptional activation mediated by coactivators TAFII40 and TAFII60
-
Thut, C. J., Chen, J. L., Klemin, R. and Tjian, R. (1995). p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60. Science 267, 100-104
-
(1995)
Science
, vol.267
, pp. 100-104
-
-
Thut, C.J.1
Chen, J.L.2
Klemin, R.3
Tjian, R.4
-
199
-
-
0033609306
-
-
Unger, T., Sionov, R. V., Moallem, E., Yee, C. L., Howley, P. M., Oren, M. and Haupt Y. (1999). Mutations in serines 15 and 20 of human p53 impair its apoptotic activity Oncogene 18, 3205-3212
-
(1999)
Mutations in Serines 15 and 20 of Human P53 Impair Its Apoptotic Activity Oncogene
, vol.18
, pp. 3205-3212
-
-
Unger, T.1
Sionov, R.V.2
Moallem, E.3
Yee, C.L.4
Howley, P.M.5
Oren, M.6
Haupt, Y.7
-
200
-
-
0028111802
-
Has the breast cancer gene been found
-
Vogelstein, B. and Kinzler, K. W. (1994). Has the breast cancer gene been found. Cell 79, 1-3
-
(1994)
Cell
, vol.79
, pp. 1-3
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
201
-
-
0027361941
-
Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood
-
Wada, M., Bartram, C. R., Nakamura, H., Hachiya, M., Chen, D. L., Borenstein, J., Miller, C. W., Ludwig, L., Hansen-Hagge, T. E., Ludwig, W. D., Reiter, A., Mizoguchi, H. and Koeffler, H. P. (1993). Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood. Blood 82, 3163-3169
-
(1993)
Blood
, vol.82
, pp. 3163-3169
-
-
Wada, M.1
Bartram, C.R.2
Nakamura, H.3
Hachiya, M.4
Chen, D.L.5
Borenstein, J.6
Miller, C.W.7
Ludwig, L.8
Hansen-Hagge, T.E.9
Ludwig, W.D.10
Reiter, A.11
Mizoguchi, H.12
Koeffler, H.P.13
-
202
-
-
0028034199
-
-
Wagner, A. J., Kokontis, J. M. and Hay, N. (1994). Myc-mediated apoptosis requires wildtype p53 in a manner independent of cell-cycle arrest and the ability of p53 to induce P21WAFI/CIPI Gmes & Development 8, 2817-2830
-
(1994)
Myc-Mediated Apoptosis Requires Wildtype P53 in a Manner Independent of Cell-Cycle Arrest and the Ability of P53 to Induce P21WAFI/CIPI Gmes & Development
, vol.8
, pp. 2817-2830
-
-
Wagner, A.J.1
Kokontis, J.M.2
Hay, N.3
-
203
-
-
0028989236
-
C. (1995). P53 modulation of TFIIH-associated nucleotide excision repair activity
-
Wang, X. W., Yeh, H., Schaeffer, L., Roy, R., Moncollin, V., Egly, J. M., Wang, Z., Freidberg, E. C., Evans, M. K., Taffe, B. G., Bohr, V. A., Weeda, G., Hoeijmakers, J. H. J., Forrester, K. and Harris, C. C. (1995). p53 modulation of TFIIH-associated nucleotide excision repair activity. Nature Genetics 10, 188-195
-
Nature Genetics
, vol.10
, pp. 188-195
-
-
Wang, X.W.1
Yeh, H.2
Schaeffer, L.3
Roy, R.4
Moncollin, V.5
Egly, J.M.6
Wang, Z.7
Freidberg, E.C.8
Evans, M.K.9
Taffe, B.G.10
Bohr, V.A.11
Weeda, G.12
Hoeijmakers, J.H.J.13
Forrester, K.14
Harris, C.15
-
204
-
-
0027744051
-
P53 domains: Identification and characterization of two autonomous DNA-binding regions
-
Wang, Y., Reed, M., Wang, P., Stenger, J. E., Mayr, G., Anderson, M. E., Schwedes, J. F. and Tegtmeyer, P. (1993). p53 domains: identification and characterization of two autonomous DNA-binding regions. Genes & Development 7, 2575-2586
-
(1993)
Genes & Development
, vol.7
, pp. 2575-2586
-
-
Wang, Y.1
Reed, M.2
Wang, P.3
Stenger, J.E.4
Mayr, G.5
Anderson, M.E.6
Schwedes, J.F.7
Tegtmeyer, P.8
-
205
-
-
0031840253
-
ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
-
Waterman, M. J., Stavridi, E. S., Waterman, J. L. and Halazonetis, T. D. (1998). ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins. Nature Genetics 19, 175-178
-
(1998)
Nature Genetics
, vol.19
, pp. 175-178
-
-
Waterman, M.J.1
Stavridi, E.S.2
Waterman, J.L.3
Halazonetis, T.D.4
-
206
-
-
0033130010
-
Nucleolar ARF sequesters Mdm2 and activates p53
-
Weber, J. D., Taylor, L. J., Roussel, M., Sherr, Cj. and Bar-Sagi, D. (1999). Nucleolar ARF sequesters Mdm2 and activates p53. Nature Cell Biology 1, 20-26
-
(1999)
Nature Cell Biology
, vol.1
, pp. 20-26
-
-
Weber, J.D.1
Taylor, L.J.2
Roussel, M.3
Sherr, C.J.4
Bar-Sagi, D.5
-
207
-
-
0026337295
-
Tumour suppressor genes
-
Weinberg, R. A. (1991). Tumour suppressor genes. Science 254, 1138-1145
-
(1991)
Science
, vol.254
, pp. 1138-1145
-
-
Weinberg, R.A.1
-
208
-
-
0029033861
-
The retinoblastoma protein and cell cycie control
-
Weinberg, R. A. (1995). The retinoblastoma protein and cell cycie control. Cell 81, 323-330
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
209
-
-
0031018994
-
Relationship of p53, bcl-2 and tumor proliferation to clinical drug resistance in non-Hodgkin's lymphomas
-
Wilson, W. H., Teruya-Feldstein, J., Fest, T., Harris, C., Steinberg, S. M., Jaffe, E. S. and Raffeld, M. (1997). Relationship of p53, bcl-2 and tumor proliferation to clinical drug resistance in non-Hodgkin's lymphomas. Blood 89, 601-609
-
(1997)
Blood
, vol.89
, pp. 601-609
-
-
Wilson, W.H.1
Teruya-Feldstein, J.2
Fest, T.3
Harris, C.4
Steinberg, S.M.5
Jaffe, E.S.6
Raffeld, M.7
-
210
-
-
0032514485
-
-
Woo, R. A., Mclure, K. G., Lees-Miller, S. P., Rancourt, D. E. and Lee, P. W. K. (1998). DNA-dependent protein kinase acts upstream of p53 in response to DNA damage Nature 394, 700-704
-
(1998)
Dna-Dependent Protein Kinase Acts Upstream of P53 in Response to DNA Damage Nature
, vol.394
, pp. 700-704
-
-
Woo, R.A.1
McLure, K.G.2
Lees-Miller, S.P.3
Rancourt, D.E.4
Lee, P.W.K.5
-
211
-
-
0031253977
-
-
Wu, G. S., Burns, T. F., Mcdonald, E. R., III, Jiang, W., Meng, R., Krantz, I. D., Kao, G., Gan, D. D., Zhou, J. Y., Muschel, R., Hamilton, S. R., Spinner, N. B., Markowitz S Wu, G. and El-Deiry, W. S. (1997). KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nature Genetics 17, 141-143
-
(1997)
KILLER/DR5 is a DNA Damage-Inducible P53-Regulated Death Receptor Gene. Nature Genetics
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald, E.R.3
Jiang, W.I.4
Meng, W.5
Krantz, R.6
Kao, I.D.7
Gan, G.8
Zhou, D.D.9
Muschel, J.Y.10
Hamilton, R.11
Spinner, S.R.12
Markowitz S Wu, N.B.13
El-Deiry, G.W.S.14
-
213
-
-
0019863092
-
Chromatin changes in apoptosis
-
Wyllie, A. H., Beattie, G. J. and Hargreaves, A. D. (1981). Chromatin changes in apoptosis. Histochemical Journal 13, 681-692
-
(1981)
Histochemical Journal
, vol.13
, pp. 681-692
-
-
Wyllie, A.H.1
Beattie, G.J.2
Hargreaves, A.D.3
-
214
-
-
0027717617
-
D. (1993). P21 is a universal inhibitor of cyclin kinases
-
Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R. and Beach, D. (1993). p21 is a universal inhibitor of cyclin kinases. Nature 366, 701-704
-
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
-
215
-
-
0032161624
-
P63 a p53 homolog at 3q27-29, encodes multiple products widi transactivating, death inducing and dominant negative activities
-
Yang, A., Kaghad, M., Wang, Y., Gillet, E., Flemming, M. D., Dotsch, V., Andrews, N. C., Caput, D. and Mckeon, F. (1998). p63 a p53 homolog at 3q27-29, encodes multiple products widi transactivating, death inducing and dominant negative activities. Molecules and Cells 2, 305-316
-
(1998)
Molecules and Cells
, vol.2
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillet, E.4
Flemming, M.D.5
Dotsch, V.6
Rews, N.C.7
Caput, D.8
McKeon, F.9
-
216
-
-
0033594485
-
-
Yang, A., Schweitzer, R., Sun, D., Kaghad, M., Walker, N., Bronson, R. T., Tabin, C., Sharpe, A., Caput, D., Crum, C. and Mckeon, F. (1999). p63 is essential for regenerative proliferation in limb, cranofacial and epithelial development Nature 398, 714-718
-
(1999)
P63 is Essential for Regenerative Proliferation in Limb, Cranofacial and Epithelial Development Nature
, vol.398
, pp. 714-718
-
-
Yang, A.1
Schweitzer, R.2
Sun, D.3
Kaghad, M.4
Walker, N.5
Bronson, R.T.6
Tabin, C.7
Sharpe, A.8
Caput, D.9
Crum, C.10
McKeon, F.11
-
217
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukaematic cells that is inhibited by interleukin-6
-
Yonish-Rouach, E., Resnjtzky, D., Lotem, D., Sachs, L., Kimchi, A. and Oren, M. (1991). Wild-type p53 induces apoptosis of myeloid leukaematic cells that is inhibited by interleukin-6. Nature 352, 345-347
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
Resnjtzky, D.2
Lotem, D.3
Sachs, L.4
Kimchi, A.5
Oren, M.6
-
218
-
-
0029973738
-
-
Yuan, Z. M., Huang, Y., Whang, Y., Sawyers, C., Weichselbaum, R., Kharbanda, S. and Kufe, D. (1996). Role for c-Abl tyrosine kinase in growth arrest response to DNA damage Nature 382, 272-274
-
(1996)
Role for C-Abl Tyrosine Kinase in Growth Arrest Response to DNA Damage Nature
, vol.382
, pp. 272-274
-
-
Yuan, Z.M.1
Huang, Y.2
Whang, Y.3
Sawyers, C.4
Weichselbaum, R.5
Kharbanda, S.6
Kufe, D.7
-
219
-
-
0033600235
-
P73 is regulated by tyrosine kinase c-Abi in the apoptotic response to DNA damage
-
Yuan, Z. M., Shioya, H., Ishiko, T., Sun, X., Gu, J., Huang, Y. Y., Lu, H., Kharbanda, S., Weichselbaum, R. and Kufe, D. (1999). p73 is regulated by tyrosine kinase c-Abi in the apoptotic response to DNA damage. Nature 399, 814-817
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
Sun, X.4
Gu, J.5
Huang, Y.Y.6
Lu, H.7
Kharbanda, S.8
Weichselbaum, R.9
Kufe, D.10
-
220
-
-
0032961828
-
MDM2 suppresses p73 function without promoting p73 degradation
-
Zeng, X., Chen, L., Jost, C. A., Maya, R., Keller, D., Wang, X., Kaelin, W. G., Oren, M., Chen, J. and Lu, H. (1999). MDM2 suppresses p73 function without promoting p73 degradation. Molecular and Cellular Biology 19, 3257-3266
-
(1999)
Molecular and Cellular Biology
, vol.19
, pp. 3257-3266
-
-
Zeng, X.1
Chen, L.2
Jost, C.A.3
Maya, R.4
Keller, D.5
Wang, X.6
Kaelin, W.G.7
Oren, M.8
Chen, J.9
Lu, H.10
-
221
-
-
0031946364
-
Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding
-
Zhan, Q., Chen, I. T., Antjnore, M. J. and Fornace, A. J., (1998). Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding. Molecular and Cellular Biology 18, 2768-2778
-
(1998)
Molecular and Cellular Biology
, vol.18
, pp. 2768-2778
-
-
Zhan, Q.1
Chen, I.T.2
Antjnore, M.J.3
Fornace, A.J.4
-
222
-
-
0033000482
-
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
-
Zhang, Y. and Xiong, Y. (1999). Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Molecules and Cells 3, 579-591
-
(1999)
Molecules and Cells
, vol.3
, pp. 579-591
-
-
Zhang, Y.1
Xiong, Y.2
-
223
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb abd p53 tumor suppressor pathways
-
Zhang, Y., Xiong, Y. and Yarbrough, W. G. (1998). ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb abd p53 tumor suppressor pathways. Cell 92, 725-734
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
224
-
-
0032145569
-
Myc signalling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
-
Zindy, P., Eischen, C. M., Randle, D. H., Kamdo, T., Cleveland, J. L., Sherr, C. J. and Roussel, M. F. (1998). Myc signalling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes & Development 12, 2424-2433
-
(1998)
Genes & Development
, vol.12
, pp. 2424-2433
-
-
Zindy, P.1
Eischen, C.M.2
Randle, D.H.3
Kamdo, T.4
Cleveland, J.L.5
Sherr, C.J.6
Roussel, M.F.7
-
225
-
-
0030745646
-
Apaf-i, a human protein homologous to C. Elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou, H., Henzel, W. J., Liu, X., Lutschg, A. and Wang, X. (1997). Apaf-i, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
|