The candidate tumour suppressor p33(ING1) cooperates with p53 in cell growth control

Nature

Volumn 391, Issue 6664, 1998, Pages 295-298

  Garkavtsev, Igor ^a,e   Grigorian, Irina A ^b   Ossovskaya, Valeria S ^c,f   Chernov, Mikhail V ^d   Chumakov, Peter M ^c   Gudkov, Andrei V ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ILLINOIS   (United States)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^d LERNER RESEARCH INSTITUTE   (United States)

^e GENOME THERAPEUTICS CORPORATION   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN; PROTEIN P33; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; FIBROBLAST; GROWTH REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, TUMOR SUPPRESSOR; GROWTH INHIBITORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NUCLEAR PROTEINS; PRECIPITIN TESTS; PROTEINS; RATS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0032518510     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/34675     Document Type: Article

References (18)

1. ING1 promotes neoplastic transformation. Nature Genet. 14, 415-420 (1996).
2. Garkavtsev, I. & Riabowol, K. Extension of the replicative life span of human diploid fibroblasts by inhibition of the p331NG1 candidate tumor suppressor. Mol Cell, Biol 17, 2014-2019 (1997).
3. Helbing, C. C., Veillette, C., Riabowol, K., Johnston, R. N. & Garkavtsev, I. A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis. Cancer Res. 57, 1255-1258 (1997).
4. Gottlieb, T. M. & Oren, M. p53 in growth control and neoplasia. Biochim. Biophys. Acta 1287, 77-102 (1996).
5. Garkavtsev, I., Demetrick, D. & Riabowol, K. Cellular localization and chromosome mapping of a novel candidate tumor suppressor gene. Cytogenet. Cell Genet. 76, 176-178 (1997).
6. ING1 candidate tumor suppressor gene. Somat. Cell Mol Genet. 23, 233-236 (1997).
7. Maestro, R. et al. Chromosome 13q deletion mapping in head and neck squamous cell carcinomas: identification of two distinct regions of preferential loss. Cancer Res. 56, 1146-1150 (1996).
8. Ossovskaya, V. S. et al. Dissection of p53 functions by genetic suppressor elements: distinct biological effects of separate p53 domains. Proc. Natl Acad. Sci. USA 93, 10309-10314 (1996).
9. El-Deiry, W. S. et al. WAF-1, a potential mediator of p53 tumor suppression. Cell 75, 817-825 (1993).
10. Kondratov, R. V. et al. Functional heterogeneity of p53-responsive elements. Mol. Biol. (Mosk.) 30, 613-620 (1996).
11. Momand, J., Zambetti, G. P., Olson, D. C., George, D. & Levine, A. J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53 mediated transactivation. Cell 69,1237-1245 (1992).
12. Jayaraman, L. et al. Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev. 11, 558-570 (1997).
13. Avantaggiati, M. L. et al Recruitment of p300/CBP in p53-dependent signal pathway. Cell 89, 1175-1184 (1997).
14. Kopnin, B. P. et al Influence of exogenous ras and p53 on P-glycoprotein function in immortalized rodent fibroblasts. Oncol. Res. 7, 299-306 (1995).
15. Pear, W. S., Nolan, G. P., Scott, M. L. & Baltimore, D. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl Acad. Sci, USA 90, 8392-8396 (1993).
16. Harvey, D. M. & Levine, A. J. p53 alteration is a common event in the sponaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5, 2375-2385 (1991).
17. Agarwal, M. L., Agarwal, A., Taylor, W. R. & Stark, G. R. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc. Natl Acad. Sci. USA 92, 8493-8497 (1995).
18. Pauwels, R. et al. Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. J. Virol. Methods 20, 309-321 (1988).