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Volumn 75, Issue 2, 1997, Pages 230-235

P53 alterations are predictive of chemoresistance and aggressiveness in ovarian carcinomas: A molecular and immunohistochemical study

Author keywords

Chemoresistance; cis diamminedichloroplatinum II (cisplatin); Immunohistochemistry; Ovarian carcinoma; p53 expression; p53 mutations; Polymerase chain reaction; Single strand conformation polymorphism

Indexed keywords

CISPLATIN; PROTEIN P53;

EID: 8044233696     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.38     Document Type: Article
Times cited : (149)

References (54)
  • 2
    • 0025047803 scopus 로고
    • Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxin and hyperthermia
    • Barry MA, Behnke CA and Eastman A (1990) Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxin and hyperthermia. Biochem Pharmacol 40: 2353-2362
    • (1990) Biochem Pharmacol , vol.40 , pp. 2353-2362
    • Barry, M.A.1    Behnke, C.A.2    Eastman, A.3
  • 3
    • 0028837632 scopus 로고
    • p53 nuclear protein expression is an independent prognostic marker in clinically localized prostate cancer patients undergoing radical prostatectomy
    • Bauer JJ, Sesterhenn IA, Mostofi KF, Mcleod DG, Srivastava S and Moul JW (1995) p53 nuclear protein expression is an independent prognostic marker in clinically localized prostate cancer patients undergoing radical prostatectomy. Clin Cancer Res 1: 1295-1300
    • (1995) Clin Cancer Res , vol.1 , pp. 1295-1300
    • Bauer, J.J.1    Sesterhenn, I.A.2    Mostofi, K.F.3    Mcleod, D.G.4    Srivastava, S.5    Moul, J.W.6
  • 5
    • 0028875410 scopus 로고
    • Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy
    • Bergh J, Norberg T, Sjogren S, Lindgren A and Holmberg L (1995) Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy. Nature Med 1: 1029-1034
    • (1995) Nature Med , vol.1 , pp. 1029-1034
    • Bergh, J.1    Norberg, T.2    Sjogren, S.3    Lindgren, A.4    Holmberg, L.5
  • 6
    • 0025832828 scopus 로고
    • The immunobiology and immunotherapy of ovarian cancer
    • Bookman MA and Bast RC (1991) The immunobiology and immunotherapy of ovarian cancer. Semin Oncol 18: 270-291
    • (1991) Semin Oncol , vol.18 , pp. 270-291
    • Bookman, M.A.1    Bast, R.C.2
  • 7
    • 0026471731 scopus 로고
    • Abnormal p53 immunoreactivity and prognosis in node-negative breast carcinomas with long-term follow-up
    • Bosari S, Lee KC, Viale G, Heatley GJ and Coggi G (1992) Abnormal p53 immunoreactivity and prognosis in node-negative breast carcinomas with long-term follow-up. Virchows Archiv A Pathol Anat 421: 291-295
    • (1992) Virchows Archiv A Pathol Anat , vol.421 , pp. 291-295
    • Bosari, S.1    Lee, K.C.2    Viale, G.3    Heatley, G.J.4    Coggi, G.5
  • 9
    • 0023709002 scopus 로고
    • A variation in the structure of the protein-coding region of the human p53 gene
    • Buchman L, Chumakov PM, Ninkina NN, Samarina OP and Georgiev GP (1988) A variation in the structure of the protein-coding region of the human p53 gene. Gene 70: 245-252
    • (1988) Gene , vol.70 , pp. 245-252
    • Buchman, L.1    Chumakov, P.M.2    Ninkina, N.N.3    Samarina, O.P.4    Georgiev, G.P.5
  • 10
    • 0027255942 scopus 로고
    • Apoptosis and disease
    • Carson DA and Ribeiro JM (1993) Apoptosis and disease. Lancet 341: 1252-1254
    • (1993) Lancet , vol.341 , pp. 1252-1254
    • Carson, D.A.1    Ribeiro, J.M.2
  • 11
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human MDRI gene by Ras and p53
    • Chin K-V, Ueda K, Pastan I, Gottesman MM (1992) Modulation of activity of the promoter of the human MDRI gene by Ras and p53. Science 255: 459-462
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.-V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 12
    • 0024988359 scopus 로고
    • Activation of programmed cell death by anticancer agents: Cisplatin as a model system
    • Eastman A (1990) Activation of programmed cell death by anticancer agents: cisplatin as a model system. Cancer Cell 2: 275-280
    • (1990) Cancer Cell , vol.2 , pp. 275-280
    • Eastman, A.1
  • 14
    • 0028951110 scopus 로고
    • C-erbB2 gene amplification and protein expression in ovarian epithelial tumours: Evaluation of their respective prognostic significance by multivariate analysis
    • Fajac A, Benard J, Lhomme C, Rey A, Duvillard P, Rochard F, Bernaudin J-F and Riou G (1995) C-erbB2 gene amplification and protein expression in ovarian epithelial tumours: evaluation of their respective prognostic significance by multivariate analysis. Int J Cancer (Pred Oncol) 64: 146-151
    • (1995) Int J Cancer (Pred Oncol) , vol.64 , pp. 146-151
    • Fajac, A.1    Benard, J.2    Lhomme, C.3    Rey, A.4    Duvillard, P.5    Rochard, F.6    Bernaudin, J.-F.7    Riou, G.8
  • 15
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • Fisher DE (1994) Apoptosis in cancer therapy: crossing the threshold. Cell 78: 539-542
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 16
    • 0025735578 scopus 로고
    • Prognostic factors in ovarian cancer
    • Friedlander ML and Dembo AJ (1991) Prognostic factors in ovarian cancer. Semin Oncol 18: 205-212
    • (1991) Semin Oncol , vol.18 , pp. 205-212
    • Friedlander, M.L.1    Dembo, A.J.2
  • 17
    • 0027233829 scopus 로고
    • Cellular accumulation of the anticancer agent cisplatin: A review
    • Gately DP and Howell SB (1993) Cellular accumulation of the anticancer agent cisplatin: a review. Br J Cancer 67: 1171-1176
    • (1993) Br J Cancer , vol.67 , pp. 1171-1176
    • Gately, D.P.1    Howell, S.B.2
  • 18
    • 0001434081 scopus 로고
    • Pathology of malignant and borderline (low malignant potential) epithelial tumours of the ovary
    • Coppleson M (ed) Churchill Livingstone: Edinburgh
    • Hart WR (1992) Pathology of malignant and borderline (low malignant potential) epithelial tumours of the ovary. In Gynecologic Oncology, Coppleson M (ed) pp. 863-887, Churchill Livingstone: Edinburgh
    • (1992) Gynecologic Oncology , pp. 863-887
    • Hart, W.R.1
  • 20
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer drugs
    • Hickman JA (1992) Apoptosis induced by anticancer drugs. Cancer metastasis Rev 11: 121-139
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 121-139
    • Hickman, J.A.1
  • 21
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL and Ling V (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 455: 152-162
    • (1976) Biochim Biophys Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 22
    • 0026508152 scopus 로고
    • Neu protein overexpression in benign, borderline, and malignant ovarian neoplasm
    • Kacinski BM, Mayer AG, King BL, Carter D and Chambers SK (1992) Neu protein overexpression in benign, borderline, and malignant ovarian neoplasm. Gynecol Oncol 44: 245-253
    • (1992) Gynecol Oncol , vol.44 , pp. 245-253
    • Kacinski, B.M.1    Mayer, A.G.2    King, B.L.3    Carter, D.4    Chambers, S.K.5
  • 23
    • 0028938994 scopus 로고
    • p53 mutations in ovarian tumours, detected by temperature-gradient gel electrophoresis, direct sequencing and immunohistochemistry
    • Kappes S, Milde-Langosch KM, Kressin P, Passlack B, Dockhorn-Dworniczak B, Rohlke P and Loning T (1995) p53 mutations in ovarian tumours, detected by temperature-gradient gel electrophoresis, direct sequencing and immunohistochemistry. Int J Cancer 64: 52-59
    • (1995) Int J Cancer , vol.64 , pp. 52-59
    • Kappes, S.1    Milde-Langosch, K.M.2    Kressin, P.3    Passlack, B.4    Dockhorn-Dworniczak, B.5    Rohlke, P.6    Loning, T.7
  • 24
    • 0028329172 scopus 로고
    • Apoptosis: Its significance in cancer and cancer therapy
    • Kerr JFR, Winterford CM and Harmon BV (1994) Apoptosis: its significance in cancer and cancer therapy. Cancer 73: 2013-2026
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.R.1    Winterford, C.M.2    Harmon, B.V.3
  • 28
    • 0028898748 scopus 로고
    • Mutant p53 protein overexpression is associated with poor outcome in patients with well or moderately differentiated ovarian carcinoma
    • Levesque MA, Katsaros D, YU H, Zola P, Sismondi P, Giardina G and Diamandis EP (1995) Mutant p53 protein overexpression is associated with poor outcome in patients with well or moderately differentiated ovarian carcinoma. Cancer 75: 1327-1338
    • (1995) Cancer , vol.75 , pp. 1327-1338
    • Levesque, M.A.1    Katsaros, D.2    Yu, H.3    Zola, P.4    Sismondi, P.5    Giardina, G.6    Diamandis, E.P.7
  • 29
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SE, Ruley HE, Jacks T and Housman DE (1993a) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.E.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 30
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe SE, Schmitt EM, Smith SW, Osborne BA and Jacks T (1993b) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.E.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 32
    • 0028891783 scopus 로고
    • Apoptosis, oncosis and necrosis
    • Majno G and Joris I (1995) Apoptosis, oncosis and necrosis. Am J Pathol 146: 3-15
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 37
    • 0027389763 scopus 로고
    • Bcl2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita T and Reed JC (1993) Bcl2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 81: 151-157
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 39
    • 0027945491 scopus 로고
    • Alteration of p53 gene in ovarian carcinoma: Clinicopathological correlation and prognostic significance
    • Niwa K, Itoh M, Murase T, Morishita S, Itoh N, Mori H and Tamaya T (1994) Alteration of p53 gene in ovarian carcinoma: clinicopathological correlation and prognostic significance. Br J Cancer 70: 1191-1197
    • (1994) Br J Cancer , vol.70 , pp. 1191-1197
    • Niwa, K.1    Itoh, M.2    Murase, T.3    Morishita, S.4    Itoh, N.5    Mori, H.6    Tamaya, T.7
  • 40
    • 0027421045 scopus 로고
    • Role of p53 tumour suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines
    • O'Connor PM, Jackman J, Jondle D, Bathia K, Magrath I and Kohn RW (1993) Role of p53 tumour suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res 53: 4776-4780
    • (1993) Cancer Res , vol.53 , pp. 4776-4780
    • O'Connor, P.M.1    Jackman, J.2    Jondle, D.3    Bathia, K.4    Magrath, I.5    Kohn, R.W.6
  • 42
    • 0024756969 scopus 로고
    • Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
    • Orita M, Suzuki Y, Sekiya T and Hayashi K (1989) Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 5: 874-879
    • (1989) Genomics , vol.5 , pp. 874-879
    • Orita, M.1    Suzuki, Y.2    Sekiya, T.3    Hayashi, K.4
  • 43
    • 0028144364 scopus 로고
    • The role of apoptosis in cell killing by cisplatin: Cytometric study
    • Ormerod MG, Orr RM and Peacock JH (1994) The role of apoptosis in cell killing by cisplatin: cytometric study. Br J Cancer 69: 93-100
    • (1994) Br J Cancer , vol.69 , pp. 93-100
    • Ormerod, M.G.1    Orr, R.M.2    Peacock, J.H.3
  • 44
    • 0027511187 scopus 로고
    • Mechanisms and modulation of resistance to chemotherapy in ovarian cancer
    • Perez RP, Hamilton TC, Ozols RF and Young RC (1993) Mechanisms and modulation of resistance to chemotherapy in ovarian cancer. Cancer 71: 1571-1580
    • (1993) Cancer , vol.71 , pp. 1571-1580
    • Perez, R.P.1    Hamilton, T.C.2    Ozols, R.F.3    Young, R.C.4
  • 47
    • 0026645022 scopus 로고
    • Immunolocalization of cmyc oncoprotein in mucinous and serous adenocarcinomas of the ovary
    • Sasano H, Nagura H and Silverberg SG (1992) Immunolocalization of cmyc oncoprotein in mucinous and serous adenocarcinomas of the ovary. Human Pathol 23: 491-495
    • (1992) Human Pathol , vol.23 , pp. 491-495
    • Sasano, H.1    Nagura, H.2    Silverberg, S.G.3
  • 49
    • 0026523778 scopus 로고
    • Induction of apoptosis by wild-type p53 in a human colon tumour-derived cell line
    • Shaw P, Bovey R, Tardy S, Sahly R, Sordat B and Costa J (1992) Induction of apoptosis by wild-type p53 in a human colon tumour-derived cell line. Proc Natl Acad Sci USA 89: 4495-4499
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4495-4499
    • Shaw, P.1    Bovey, R.2    Tardy, S.3    Sahly, R.4    Sordat, B.5    Costa, J.6
  • 50
    • 0025813473 scopus 로고
    • Protocols for an improved detection of point mutations by SSCP
    • Spinardi L, Mazars R and Theillet C (1991) Protocols for an improved detection of point mutations by SSCP. Nucleic Acid Res 19: 4009
    • (1991) Nucleic Acid Res , vol.19 , pp. 4009
    • Spinardi, L.1    Mazars, R.2    Theillet, C.3
  • 52
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson C B (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 53
  • 54
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A and Oren M (1991) Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352: 345-350
    • (1991) Nature , vol.352 , pp. 345-350
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6


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