-
1
-
-
0029050533
-
Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes and apoptosis
-
Almasan, A., Yin, Y., Kelly, R., Lee, Y.-H.P., Bradley, A., Li, W., Bertino, J.R. and Wahl, G.M. (1995) Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes and apoptosis. Proc. Natl Acad. Sci. USA, 92, 5436-5440.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 5436-5440
-
-
Almasan, A.1
Yin, Y.2
Kelly, R.3
Lee, Y.-H.P.4
Bradley, A.5
Li, W.6
Bertino, J.R.7
Wahl, G.M.8
-
2
-
-
0029747143
-
Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginai discs
-
Asano, M., Nevins, J.R. and Wharton, R. (1996) Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginai discs. Genes Dev., 10, 1422-1432.
-
(1996)
Genes Dev.
, vol.10
, pp. 1422-1432
-
-
Asano, M.1
Nevins, J.R.2
Wharton, R.3
-
3
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
-
Attardi, L.D., Lowe, S.W., Brugarolas, J. and Jacks, T. (1996) Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J., 15, 3693-3701.
-
(1996)
EMBO J.
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
4
-
-
0026689930
-
Cell death and control of cell survival in the oligodendrocyte lineage
-
Barres, B.A., Hart, I.K., Coles, H.S.R., Burne, J.F., Voyvodic, J.T., Richardson, W.D. and Raff, M.C. (1992) Cell death and control of cell survival in the oligodendrocyte lineage. Cell, 70, 31-46.
-
(1992)
Cell
, vol.70
, pp. 31-46
-
-
Barres, B.A.1
Hart, I.K.2
Coles, H.S.R.3
Burne, J.F.4
Voyvodic, J.T.5
Richardson, W.D.6
Raff, M.C.7
-
5
-
-
0027299467
-
Multiple extracellular signals are required for long-term oligodendrocyte survival
-
Barres, B.A., Schmid, R., Sendnter, M. and Raff, M.C. (1993) Multiple extracellular signals are required for long-term oligodendrocyte survival. Development, 118, 283-295.
-
(1993)
Development
, vol.118
, pp. 283-295
-
-
Barres, B.A.1
Schmid, R.2
Sendnter, M.3
Raff, M.C.4
-
6
-
-
0028849615
-
Influence of growth factors on neuronal differentiation
-
Birling, M.-C. and Price, J. (1995) Influence of growth factors on neuronal differentiation. Curr. Opin. Cell Biol., 7, 878-884.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 878-884
-
-
Birling, M.-C.1
Price, J.2
-
7
-
-
0029043839
-
Direct transcriptional repression by Rb and its reversal by specific cyclins
-
Bremner, R., Cohen, B.L., Sopta, M., Hamel, P.A., Ingles, C.J., Gallie, B.L. and Phillips, R.A. (1995) Direct transcriptional repression by Rb and its reversal by specific cyclins. Mol. Cell. Biol., 15, 3256-3265.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3256-3265
-
-
Bremner, R.1
Cohen, B.L.2
Sopta, M.3
Hamel, P.A.4
Ingles, C.J.5
Gallie, B.L.6
Phillips, R.A.7
-
8
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas, J., Chandrasekaran, C., Gordon, J.I., Beach, D., Jacks, T. and Hannon, G.J. (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature, 377, 552-557.
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
9
-
-
0027186004
-
Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons
-
Buchman, V.L. and Davies, A.M. (1993) Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons. Development, 118, 989-1001.
-
(1993)
Development
, vol.118
, pp. 989-1001
-
-
Buchman, V.L.1
Davies, A.M.2
-
10
-
-
0028864667
-
Induction of the growth inhibitor IGF-binding protein 3 by p53
-
Buckbinder, L., Talbott, R., Velasco-Miguel, S., Takenaka, I., Faha, B., Seizinger, B.R. and Kley, N. (1995) Induction of the growth inhibitor IGF-binding protein 3 by p53. Nature, 377, 646-649.
-
(1995)
Nature
, vol.377
, pp. 646-649
-
-
Buckbinder, L.1
Talbott, R.2
Velasco-Miguel, S.3
Takenaka, I.4
Faha, B.5
Seizinger, B.R.6
Kley, N.7
-
11
-
-
0028958705
-
Growth factor modulation of p53-mediated growth arrest versus apoptosis
-
Canman, C.E., Gilmer, T.M., Coutts, S.B. and Kastan, M.B. (1995) Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev., 9, 600-611.
-
(1995)
Genes Dev.
, vol.9
, pp. 600-611
-
-
Canman, C.E.1
Gilmer, T.M.2
Coutts, S.B.3
Kastan, M.B.4
-
12
-
-
0026609875
-
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F
-
Cao, L., Faha, B., Dembski, M., Tsai, L.H., Harlow, E. and Dyson, N. (1992) Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature, 355, 176-179.
-
(1992)
Nature
, vol.355
, pp. 176-179
-
-
Cao, L.1
Faha, B.2
Dembski, M.3
Tsai, L.H.4
Harlow, E.5
Dyson, N.6
-
13
-
-
0028783782
-
Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes
-
Cheng, S., Schmidt-Grimminger, D.C., Murant, T., Broker, T.R. and Chow, L.T. (1995) Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes. Genes Dev., 9, 2335-2349.
-
(1995)
Genes Dev.
, vol.9
, pp. 2335-2349
-
-
Cheng, S.1
Schmidt-Grimminger, D.C.2
Murant, T.3
Broker, T.R.4
Chow, L.T.5
-
14
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke, A.R., Maandag, E.R., van Roon, M., van der Lugt, N.M.T., van der Valk, M., Hooper, M.L., Berns, A. and te Riele, H. (1992) Requirement for a functional Rb-1 gene in murine development. Nature, 359, 328-330.
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
Maandag, E.R.2
Van Roon, M.3
Van Der Lugt, N.M.T.4
Van Der Valk, M.5
Hooper, M.L.6
Berns, A.7
Te Riele, H.8
-
15
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke, A.R., Purdie, C.A., Harrison, D.J., Morris, R.G., Bird, C.C., Hooper, M.L. and Wyllie, A.H. (1993) Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature, 362, 849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
16
-
-
0029049577
-
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis and G1/S regulatory genes
-
DeGregori, J., Kowalik, T. and Nevins, J.R. (1995a) Cellular targets for activation by the E2F1 transcription factor include DNA synthesis and G1/S regulatory genes. Mol. Cell. Biol., 15, 4215-4224.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4215-4224
-
-
DeGregori, J.1
Kowalik, T.2
Nevins, J.R.3
-
17
-
-
0028826881
-
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity
-
DeGregori, J., Leone, G., Ohtani, K., Miron, A. and Nevins, J.R. (1995b) E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity. Genes Dev., 9, 2873-2887.
-
(1995)
Genes Dev.
, vol.9
, pp. 2873-2887
-
-
DeGregori, J.1
Leone, G.2
Ohtani, K.3
Miron, A.4
Nevins, J.R.5
-
18
-
-
0028978183
-
Mice lacking p21Cip1/Waf1 undergo normal development, but are defective in G1 checkpoint control
-
Deng, C., Zhang, P., Harper, J.W., Elledge, S.I. and Leder, P. (1995) Mice lacking p21Cip1/Waf1 undergo normal development, but are defective in G1 checkpoint control. Cell, 82, 675-684.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.I.4
Leder, P.5
-
19
-
-
0027970713
-
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of CIP-1 in normal human fibroblasts
-
Di Leonardo, A., Linke, S.P., Clarkin, K. and Wahl, G.M. (1994) DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of CIP-1 in normal human fibroblasts. Genes Dev., 8, 2540-2551.
-
(1994)
Genes Dev.
, vol.8
, pp. 2540-2551
-
-
Di Leonardo, A.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
20
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry, W.S. et al. (1993) WAF1, a potential mediator of p53 tumor suppression. Cell, 75, 817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
-
21
-
-
0028294605
-
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
El-Deiry, W.S. et al. (1994) WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res., 54, 1169-1174.
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
-
22
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
Friend, S.J., Bernards, R., Rogelj, S., Weinberg, R.A., Rapaport, J.M., Albert, D.M. and Dryja, T.P. (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature, 323, 643-646.
-
(1986)
Nature
, vol.323
, pp. 643-646
-
-
Friend, S.J.1
Bernards, R.2
Rogelj, S.3
Weinberg, R.A.4
Rapaport, J.M.5
Albert, D.M.6
Dryja, T.P.7
-
23
-
-
0027499060
-
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
-
Gu, W., Schneider, J.W., Condorelli, G., Kaushal, S., Mahdavl, V. and Nadal-Ginard, B. (1993) Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell, 72, 309-324.
-
(1993)
Cell
, vol.72
, pp. 309-324
-
-
Gu, W.1
Schneider, J.W.2
Condorelli, G.3
Kaushal, S.4
Mahdavl, V.5
Nadal-Ginard, B.6
-
24
-
-
0027489384
-
Clinical implications of the p53 tumor-suppressor gene
-
Harris, C.C. and Hollstein, M. (1993) Clinical implications of the p53 tumor-suppressor gene. N. Engl. J. Med., 329, 1318-1327.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1318-1327
-
-
Harris, C.C.1
Hollstein, M.2
-
25
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell, L.H. and Kastan, M.B. (1994) Cell cycle control and cancer. Science, 266, 1821-1828.
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
26
-
-
0027382336
-
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein
-
Helin, K., Harlow, E. and Fattaey, A.R. (1993) Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Mol. Cell. Biol., 13, 6501-6508.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6501-6508
-
-
Helin, K.1
Harlow, E.2
Fattaey, A.R.3
-
27
-
-
0029863840
-
Altered cell cycle kinetics, gene expression and G1 restriction point regulation in Rb-deficient fibroblasts
-
Herrera, R.E., Sah, V.P., Williams, B.O., Makela, T.P., Weinberg, R.A. and Jacks, T. (1996) Altered cell cycle kinetics, gene expression and G1 restriction point regulation in Rb-deficient fibroblasts. Mol. Cell. Biol., 16, 2402-2407.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2402-2407
-
-
Herrera, R.E.1
Sah, V.P.2
Williams, B.O.3
Makela, T.P.4
Weinberg, R.A.5
Jacks, T.6
-
28
-
-
0026537277
-
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F
-
Hiebert, S.W., Chellappan, S.P., Horowitz, J.M. and Nevins, J.R. (1992) The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev. 6, 177-185.
-
(1992)
Genes Dev.
, vol.6
, pp. 177-185
-
-
Hiebert, S.W.1
Chellappan, S.P.2
Horowitz, J.M.3
Nevins, J.R.4
-
29
-
-
0028276864
-
Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter
-
Hsiao, K.M., McMahon, S.L. and Farnham, P.J. (1994) Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev., 8, 1526-1537.
-
(1994)
Genes Dev.
, vol.8
, pp. 1526-1537
-
-
Hsiao, K.M.1
McMahon, S.L.2
Farnham, P.J.3
-
30
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks, T., Fazeli, A., Schmidt, E., Bronson, R., Goodell, M. and Weinberg.R. (1992) Effects of an Rb mutation in the mouse. Nature, 359, 295-300.
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmidt, E.3
Bronson, R.4
Goodell, M.5
Weinberg, R.6
-
31
-
-
0027491775
-
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
-
Johnson, D.G., Schwarz, J.K., Cress, W.D. and Nevins, J.R. (1993) Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature, 365, 349-352.
-
(1993)
Nature
, vol.365
, pp. 349-352
-
-
Johnson, D.G.1
Schwarz, J.K.2
Cress, W.D.3
Nevins, J.R.4
-
32
-
-
0028364529
-
Autoregulatory control of E2F1 expression in response to positive and negative regulators of the cell cycle
-
Johnson, D.G., Ohtani, K. and Nevins, J.R. (1994) Autoregulatory control of E2F1 expression in response to positive and negative regulators of the cell cycle. Genes Dev., 8, 1514-1525.
-
(1994)
Genes Dev.
, vol.8
, pp. 1514-1525
-
-
Johnson, D.G.1
Ohtani, K.2
Nevins, J.R.3
-
33
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan, M.B., Onyekwere, O., Sidransky, D., Vogelstein, B. and Craig, R.W. (1991) Participation of p53 protein in the cellular response to DNA damage. Cancer Res., 51, 6304-6311.
-
(1991)
Cancer Res.
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
34
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan, M., Zhan, Q., El-Deiry, W.S., Carrier, F., Jacks, T., Walsh, W.V., Plunkett, B.S., Vogelstein, B. and Fornace, A.J., Jr (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell, 71, 587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace Jr., A.J.9
-
35
-
-
0027284241
-
Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1
-
Kiyokawa, H., Richon, V.M., Venta-Perez, G., Rifkind, R.A. and Marks, P.A. (1993) Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1. Proc. Natl Acad. Sci. USA, 90, 6746-6750.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 6746-6750
-
-
Kiyokawa, H.1
Richon, V.M.2
Venta-Perez, G.3
Rifkind, R.A.4
Marks, P.A.5
-
36
-
-
0028960617
-
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
-
Kowalik, T.F., DeGregori, J., Schwarz, J.K. and Nevins, J.R. (1995) E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol., 69, 2491-2500.
-
(1995)
J. Virol.
, vol.69
, pp. 2491-2500
-
-
Kowalik, T.F.1
DeGregori, J.2
Schwarz, J.K.3
Nevins, J.R.4
-
37
-
-
0030031514
-
Cyclin D1 is an essential mediator of apoptotic neuronal cell death
-
Kranenburg, O., van der Eb, A.J. and Zantema, A. (1996) Cyclin D1 is an essential mediator of apoptotic neuronal cell death. EMBO J., 15, 46-54.
-
(1996)
EMBO J.
, vol.15
, pp. 46-54
-
-
Kranenburg, O.1
Van Der Eb, A.J.2
Zantema, A.3
-
38
-
-
0027316813
-
An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
-
Lam, E.-F. and Watson, R.J. (1993) An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J., 12, 2705-2713.
-
(1993)
EMBO J.
, vol.12
, pp. 2705-2713
-
-
Lam, E.-F.1
Watson, R.J.2
-
39
-
-
0028032677
-
Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal
-
Lassar, A.B., Skapek, S.X. and Novitch, B. (1994) Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr. Opin. Cell Biol., 6, 788-794.
-
(1994)
Curr. Opin. Cell Biol.
, vol.6
, pp. 788-794
-
-
Lassar, A.B.1
Skapek, S.X.2
Novitch, B.3
-
40
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee, E.Y.-H.P., Chang, C.-Y., Hu, N., Wang, Y.-C. J., Lai, C.-C., Herrup, K. and Lee, W.-H. (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature, 359, 288-295.
-
(1992)
Nature
, vol.359
, pp. 288-295
-
-
Lee, E.Y.-H.P.1
Chang, C.-Y.2
Hu, N.3
Wang, Y.-C.J.4
Lai, C.-C.5
Herrup, K.6
Lee, W.-H.7
-
41
-
-
0028131540
-
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
-
Lee, E.Y.-H.P., Hu, N., Yuan, S.-S.F., Cox, L.A., Bradley, A., Lee, W.-H. and Herrup, K. (1994) Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev., 8, 2008-2021.
-
(1994)
Genes Dev.
, vol.8
, pp. 2008-2021
-
-
Lee, E.Y.-H.P.1
Hu, N.2
Yuan, S.-S.F.3
Cox, L.A.4
Bradley, A.5
Lee, W.-H.6
Herrup, K.7
-
42
-
-
0027362625
-
The retinoblastoma protein binds to a family of E2F transcription factors
-
Lees, J.A., Saito, M., Vidal, M., Valentino, M., Look, T., Harlow, E., Dyson, N. and Helin, K. (1993) The retinoblastoma protein binds to a family of E2F transcription factors. Mol. Cell. Biol., 13, 7813-7825.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7813-7825
-
-
Lees, J.A.1
Saito, M.2
Vidal, M.3
Valentino, M.4
Look, T.5
Harlow, E.6
Dyson, N.7
Helin, K.8
-
43
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S.W., Schmitt, E.S., Smith, S.W., Osborne, B.A. and Jacks, T. (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature, 362, 847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.S.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
44
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe, S.W., Bodis, S., McClatchey, A., Remington, L., Ruley, H.E., Fisher, D.E., Housman, D.E. and Jacks, T. (1994) p53 status and the efficacy of cancer therapy in vivo. Science, 266, 807-810.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
45
-
-
0028101051
-
Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice
-
Maandag, E.C.R., van der Valk, M., Vlaar, M., Feltkamp, C., O'Brien, J., van Roon, M., van der Lugt, N., Berns, A. and te Riele, H. (1994) Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice. EMBO J., 13, 4260-4268.
-
(1994)
EMBO J.
, vol.13
, pp. 4260-4268
-
-
Maandag, E.C.R.1
Van Der Valk, M.2
Vlaar, M.3
Feltkamp, C.4
O'Brien, J.5
Van Roon, M.6
Van Der Lugt, N.7
Berns, A.8
Te Riele, H.9
-
46
-
-
0027315653
-
p53 and the Li-Fraumeni syndrome
-
Malkin, D. (1993) p53 and the Li-Fraumeni syndrome. Cancer Genet. Cytogenet., 66, 83-92.
-
(1993)
Cancer Genet. Cytogenet.
, vol.66
, pp. 83-92
-
-
Malkin, D.1
-
47
-
-
0025633582
-
Germline p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin, D., Li, F.P., Strong, L.C., Fraumeni, J.F.J., Nelson, C.E. and Kim, D.H. (1990) Germline p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science, 250, 1233-1238.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni, J.F.J.4
Nelson, C.E.5
Kim, D.H.6
-
48
-
-
0029028353
-
Stimulation of E2F1/DP1 transcriptional activity by mdm2 oncoprotein
-
Martin, K., Trouche, D., Hagemeier, C., Sorensen, T.S., La Thangue, N.B. and Kouzarides, T. (1995) Stimulation of E2F1/DP1 transcriptional activity by mdm2 oncoprotein. Nature, 375, 691-694.
-
(1995)
Nature
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Sorensen, T.S.4
La Thangue, N.B.5
Kouzarides, T.6
-
49
-
-
0026562757
-
The HIP1 binding site is required for growth regulation of the dehydrofolate reductase promoter
-
Means, A.L., Slansky, J.E., McMahon, S.L., Knuth, M.W. and Farnham, P.J. (1992) The HIP1 binding site is required for growth regulation of the dehydrofolate reductase promoter. Mol Cell. Biol., 12, 1054-1063.
-
(1992)
Mol Cell. Biol.
, vol.12
, pp. 1054-1063
-
-
Means, A.L.1
Slansky, J.E.2
McMahon, S.L.3
Knuth, M.W.4
Farnham, P.J.5
-
50
-
-
0029051336
-
Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo
-
Midgley, C.A., Owens, B., Briscoe, C.V., Thomas, D.B., Lane, D.P. and Hall, P.A. (1995) Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo. J. Cell Sci., 108, 1843-1848.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 1843-1848
-
-
Midgley, C.A.1
Owens, B.2
Briscoe, C.V.3
Thomas, D.B.4
Lane, D.P.5
Hall, P.A.6
-
51
-
-
0027934570
-
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
-
Morgenbesser, S.D., Williams, B.O., Jacks, T. and DePinho, R.A. (1994) p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature, 371, 72-75.
-
(1994)
Nature
, vol.371
, pp. 72-75
-
-
Morgenbesser, S.D.1
Williams, B.O.2
Jacks, T.3
DePinho, R.A.4
-
52
-
-
0028918028
-
Transcriptional regulation during the mammalian cell cycle
-
Muller, R. (1995) Transcriptional regulation during the mammalian cell cycle. Trends Genet., 11, 173-178.
-
(1995)
Trends Genet.
, vol.11
, pp. 173-178
-
-
Muller, R.1
-
53
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
Nevins, J. (1992) E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science, 258, 424-429.
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.1
-
54
-
-
0029583648
-
Regulation of the cyclin e gene by transcription factor E2F1
-
Ohtani, K., DeGregor, J. and Nevins, J.R. (1995) Regulation of the cyclin E gene by transcription factor E2F1. Proc. Natl Acad. Sci. USA, 92, 12146-12150.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 12146-12150
-
-
Ohtani, K.1
DeGregor, J.2
Nevins, J.R.3
-
55
-
-
0028334011
-
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
-
Pan, H. and Griep, A. (1994) Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev., 8, 1285-1299.
-
(1994)
Genes Dev.
, vol.8
, pp. 1285-1299
-
-
Pan, H.1
Griep, A.2
-
56
-
-
0029093605
-
Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
-
Pan, H. and Griep, A.E. (1995) Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev, 9, 2157-2169.
-
(1995)
Genes Dev
, vol.9
, pp. 2157-2169
-
-
Pan, H.1
Griep, A.E.2
-
57
-
-
0027771333
-
The DNA-binding domain of p53 contains four conserved regions and the major mutation hot spots
-
Pavletich, N.P., Chambers, K.A. and Pabo, C.O. (1993) The DNA-binding domain of p53 contains four conserved regions and the major mutation hot spots. Genes Dev., 7, 2556-2564.
-
(1993)
Genes Dev.
, vol.7
, pp. 2556-2564
-
-
Pavletich, N.P.1
Chambers, K.A.2
Pabo, C.O.3
-
58
-
-
0027958176
-
Neuronal cell death: Searching for the smoking gun
-
Pittman, R.N., Mills, J.C., DiBenedetto, A.J., Hynicka, W.N. and Wang, S. (1994) Neuronal cell death: searching for the smoking gun. Curr. Opin. Neurobiol., 4, 87-94.
-
(1994)
Curr. Opin. Neurobiol.
, vol.4
, pp. 87-94
-
-
Pittman, R.N.1
Mills, J.C.2
DiBenedetto, A.J.3
Hynicka, W.N.4
Wang, S.5
-
59
-
-
0027947383
-
Deregulated transcription factor E2F1 expression leads to S-phase entry and p53-mediated apoptosis
-
Qin, X.Q., Livingston, D.M., Kaelin, W.G. and Adams, P.D. (1994) Deregulated transcription factor E2F1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl Acad. Sci. USA, 91, 10918-10922.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.Q.1
Livingston, D.M.2
Kaelin, W.G.3
Adams, P.D.4
-
60
-
-
0027373764
-
Programmed cell death and the control of cell survival: Lessons from the nervous system
-
Raff, M.C., Barres, B.A., Burne, J.F., Coles, H.S., Ishizaki, Y. and Jacobson, M.D. (1993) Programmed cell death and the control of cell survival: lessons from the nervous system. Science, 262, 695-700.
-
(1993)
Science
, vol.262
, pp. 695-700
-
-
Raff, M.C.1
Barres, B.A.2
Burne, J.F.3
Coles, H.S.4
Ishizaki, Y.5
Jacobson, M.D.6
-
61
-
-
0026896116
-
Expression and phosphorylation of the retinoblastoma protein during induced differentiation of murine erythroleukemia cells
-
Richon, V., Rifkind, R.A. and Marks, P.A. (1992) Expression and phosphorylation of the retinoblastoma protein during induced differentiation of murine erythroleukemia cells. Cell Growth Differ., 3, 413-420.
-
(1992)
Cell Growth Differ.
, vol.3
, pp. 413-420
-
-
Richon, V.1
Rifkind, R.A.2
Marks, P.A.3
-
62
-
-
0029143395
-
Essential role for p53-mediated transcriplion in E1A-induced apoptosis
-
Sabbatini, P., Lin, J., Levine, A.J. and White, E. (1995) Essential role for p53-mediated transcriplion in E1A-induced apoptosis. Genes Dev., 9, 2184-2192.
-
(1995)
Genes Dev.
, vol.9
, pp. 2184-2192
-
-
Sabbatini, P.1
Lin, J.2
Levine, A.J.3
White, E.4
-
63
-
-
0028339957
-
Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells
-
Schneider, J.W., Gu, W., Zhu, L., Mahdavi, V. and Nadal-Ginard, B. (1994) Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells. Science, 264, 1467-1471.
-
(1994)
Science
, vol.264
, pp. 1467-1471
-
-
Schneider, J.W.1
Gu, W.2
Zhu, L.3
Mahdavi, V.4
Nadal-Ginard, B.5
-
64
-
-
0028952009
-
Molecular genetics of neuronal survival
-
Silos-Santiago, I., Greenlund, L.J.S., Johnson, E.M., Jr and Snider, W.D. (1995) Molecular genetics of neuronal survival. Curr. Opin. Neurobiol., 5, 42-49.
-
(1995)
Curr. Opin. Neurobiol.
, vol.5
, pp. 42-49
-
-
Silos-Santiago, I.1
Greenlund, L.J.S.2
Johnson Jr., E.M.3
Snider, W.D.4
-
65
-
-
0028360766
-
Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
-
Singh, P., Wong, S.W. and Hong, W. (1994) Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J., 13, 3329-3338.
-
(1994)
EMBO J.
, vol.13
, pp. 3329-3338
-
-
Singh, P.1
Wong, S.W.2
Hong, W.3
-
66
-
-
0028914946
-
Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins
-
Slack, R.S., Skerjanc, I.S., Lach, B., Craig, J., Jardine, K. and McBurney, M.W. (1995) Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins. J. Cell Biol., 129, 779-788.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 779-788
-
-
Slack, R.S.1
Skerjanc, I.S.2
Lach, B.3
Craig, J.4
Jardine, K.5
McBurney, M.W.6
-
67
-
-
0027403342
-
A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter
-
Slansky, J.E., Li, Y., Kaelin, W.G. and Farnham, P.J. (1993) A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter. Mol. Cell. Biol., 13, 1610-1618.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1610-1618
-
-
Slansky, J.E.1
Li, Y.2
Kaelin, W.G.3
Farnham, P.J.4
-
68
-
-
0028177401
-
p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein
-
Slebos, R.J.C., Lee, M.H., Plunkett, B.S., Kessis, T.D., Williams, B.O., Jacks, T., Hedrick, L., Kastan, M.B. and Cox, K.R. (1994) p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc. Natl Acad. Sci. USA, 91, 5320-5324.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 5320-5324
-
-
Slebos, R.J.C.1
Lee, M.H.2
Plunkett, B.S.3
Kessis, T.D.4
Williams, B.O.5
Jacks, T.6
Hedrick, L.7
Kastan, M.B.8
Cox, K.R.9
-
69
-
-
0028072523
-
DNA Damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by bcl-2
-
Strasser, A., Harris, A.W., Jacks, T.J. and Cory, S. (1994) DNA Damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by bcl-2. Cell, 79, 329-339.
-
(1994)
Cell
, vol.79
, pp. 329-339
-
-
Strasser, A.1
Harris, A.W.2
Jacks, T.J.3
Cory, S.4
-
70
-
-
0028169994
-
p53-dependent apoptosis suppresses tumor growth and progression in vivo
-
Symonds, H., Krall, L., Remington, L., Saenz-Robles, M., Lowe, S., Jacks, T. and Van Dyke, T. (1994) p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell, 78, 703-711.
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
Saenz-Robles, M.4
Lowe, S.5
Jacks, T.6
Van Dyke, T.7
-
71
-
-
0027236269
-
Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes
-
Vousden, K. (1993) Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes. FASEB J., 7, 872-879.
-
(1993)
FASEB J.
, vol.7
, pp. 872-879
-
-
Vousden, K.1
-
72
-
-
0029003061
-
Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
-
Wang, Y. and Prives, C. (1995) Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature, 376, 88-91.
-
(1995)
Nature
, vol.376
, pp. 88-91
-
-
Wang, Y.1
Prives, C.2
-
73
-
-
0026716167
-
The retinoblastoma gene and gene product
-
Levine, A.J. (ed.). Cold Spring Harbor Laboratory Press, Plainview, NY
-
Weinberg, R.A. (1992) The retinoblastoma gene and gene product. In Levine, A.J. (ed.). Tumor Suppressor Genes, the Cell Cycle, and Cancer. Cold Spring Harbor Laboratory Press, Plainview, NY, pp. 43-57.
-
(1992)
Tumor Suppressor Genes, the Cell Cycle, and Cancer
, pp. 43-57
-
-
Weinberg, R.A.1
-
74
-
-
0029043782
-
Mechanisms of active transcriptional repression by Rb
-
Weintraub, S.J., Chow, K.N.B., Luo, R.X., Zhang, S.H., He, S. and Dean, D.C. (1995) Mechanisms of active transcriptional repression by Rb. Nature, 375, 812-815.
-
(1995)
Nature
, vol.375
, pp. 812-815
-
-
Weintraub, S.J.1
Chow, K.N.B.2
Luo, R.X.3
Zhang, S.H.4
He, S.5
Dean, D.C.6
-
75
-
-
0000019122
-
In situ hybridisation
-
Stern, C.D. and Holland, P.W.H. (eds), IRL Press, Oxford
-
Wilkinson, D.G. (1993) In situ hybridisation. In Stern, C.D. and Holland, P.W.H. (eds), Essential Developmental Biology, IRL Press, Oxford, pp. 257-274.
-
(1993)
Essential Developmental Biology
, pp. 257-274
-
-
Wilkinson, D.G.1
-
76
-
-
0028136594
-
Cooperative tumorigenic effects of germline mutations in Rb and p53
-
Williams, B.O., Remington, L., Bronson, R.T., Mukai, S., Albert, D.M., Dryja, T. and Jacks, T. (1994a) Cooperative tumorigenic effects of germline mutations in Rb and p53. Nature Genet., 7, 480-484.
-
(1994)
Nature Genet.
, vol.7
, pp. 480-484
-
-
Williams, B.O.1
Remington, L.2
Bronson, R.T.3
Mukai, S.4
Albert, D.M.5
Dryja, T.6
Jacks, T.7
-
77
-
-
0027968207
-
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences
-
Williams, B.O., Schmitt, E.M., Remington, L., Bronson, R.T., Albert, D.M., Weinberg, R.A. and Jacks, T. (1994b) Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences. EMBO J., 13, 4251-4259.
-
(1994)
EMBO J.
, vol.13
, pp. 4251-4259
-
-
Williams, B.O.1
Schmitt, E.M.2
Remington, L.3
Bronson, R.T.4
Albert, D.M.5
Weinberg, R.A.6
Jacks, T.7
-
78
-
-
0028222124
-
p53 and E2F-1 cooperate to mediate apoptosis
-
Wu, X. and Levine, A.J. (1994) p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl Acad. Sci. USA, 91, 3802-3806.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 3802-3806
-
-
Wu, X.1
Levine, A.J.2
-
79
-
-
0028945789
-
Multiple members of the E2F transcription factor family are the products of oncogenes
-
Xu, G., Livingston, D.M. and Krek, W. (1995) Multiple members of the E2F transcription factor family are the products of oncogenes. Proc. Natl Acad. Sci. USA, 92, 1357-1361.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 1357-1361
-
-
Xu, G.1
Livingston, D.M.2
Krek, W.3
-
80
-
-
0029967723
-
Cell cycle regulation of E2F site occupation in vivo
-
Zwicker, J., Liu, N., Engeland, K., Lucibello, F.C. and Muller, R. (1996) Cell cycle regulation of E2F site occupation in vivo. Science, 271, 1595-1597.
-
(1996)
Science
, vol.271
, pp. 1595-1597
-
-
Zwicker, J.1
Liu, N.2
Engeland, K.3
Lucibello, F.C.4
Muller, R.5
|