MEKK1/JNK signaling stabilizes and activates p53

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 18, 1998, Pages 10541-10546

  Fuchs, Serge Y ^a   Adler, Victor ^a   Pincus, Matthew R ^b   Ronai, Ze'ev ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN KINASE; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CANCER CELL CULTURE; COMPUTER MODEL; ENZYME BINDING; ENZYME INDUCTION; FIBROBLAST; GENE ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; STRESS; TUMOR SUPPRESSOR GENE;

APOPTOSIS; CELL LINE, TRANSFORMED; CELLS, CULTURED; COMPUTER SIMULATION; HUMANS; MAP KINASE KINASE KINASE 1; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS;

ANIMALIA;

EID: 0032167915     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.18.10541     Document Type: Article

References (46)

1. Levine, A. J. (1997) Cell 88, 323-331.
2. Haffner, R. & Oren, M., (1995) Curr. Opin. Genet. Dev. 5, 84-90.
3. Adler, V., Pincus, M. R., Minamoto, T., Fuchs, S. Y., Bluth, M. J., Brandt-Rauf, P. W., Friedman, F. K., Robinson, R. C., Chen, J. M., Wang, X. W., Harris, C. C. & Ronai, Z. (1997) Proc. Natl. Acad. Sci. USA 94, 1686-1691.
4. Lees-Miller, S. P., Sakaguchi, K., Ullrich, S. J., Appella, E. & Anderson, C. W. (1992) Mol. Cell. Biol. 12, 5041-5049.
5. Wang, Y. & Eckhart, W. (1992) Proc. Natl. Acad. Sci. USA 89, 4231-4235.
6. Milne, D. M., Campbell, L. E., Campbell, D. G. & Meek, D. W. (1995) J. Biol. Chem. 270, 5511-5518.
7. Knippschild, U., Milne, D. M., Campbell, L. E., DeMaggio, A. J., Christenson, E., Hoekstra, M. F. & Meek, D. W. (1997) Oncogene 15, 1727-1736.
8. Ko, L. J., Shieh, S. Y., Chen, X., Jayaraman, L., Tamai, K., Taya, Y., Prives, C. & Pan, Z. Q. (1997) Mol. Cell. Biol. 17, 7220-7229.
9. Shieh, S. Y., Ikeda, M., Taya, Y. & Prives, C. (1997) Cell 91, 325-334.
10. Siliciano, J. D., Canman, C. E., Taya, Y., Sakaguchi, K., Appella, E. & Kastan, M. B. (1997) Genes Dev. 11, 3471-3481.
11. Fried, L. M., Koumenis, C., Peterson, S. R., Green, S. L., van Zijl, P., Allaunis-Turner, J., Chen, D. J., Fishel, R., Giaccia, A. J., Brown, J. M. & Kirchgessner, C. U. (1996) Proc. Natl. Acad. Sci. USA 93, 13825-13830.
12. Guidos, C. J., Williams, C. J., Grandal, I., Knowles, G., Huang, M. T. F. & Danska, J. S. (1996) Genes Dev. 10, 2038-2054.
13. Kyriakis, J. M. & Avruch, J. (1996) J. Biol. Chem. 271, 24313-24316.
14. Deng, T. & Karin, M. (1993) Genes Dev. 7, 479-490.
15. Adler, V., Schaffer, A., Kim, J., Dolan, L. & Ronai, Z. (1995) J. Biol. Chem. 270, 26071-26077.
16. Galcheva-Gargova, Z., Derijard, B., Wu, I. H. & Davis, R. J. (1994) Science 265, 806-808.
17. Westwick, J. K., Weitzel, C., Minden, A., Karin, M. & Brenner D. A. (1994) J. Biol. Chem. 269, 26396-26401.
18. Minden, A., Lin, A., McMahon, M., Lange-Carter, C., Derijard, B., Davis, R. J., Johnson, G. L. & Karin, M. (1994) Science 266, 1719-1723.
19. Lin, A., Minden, Martinetto, H., Clarett, F.-X., Lange-Carter, C., Mercurio, F., Johnson, G. L. & Karin, M. (1995) Science 268, 286-290.
20. Yang, D., Tournier, C., Wysk, M., Lu, H. T., Xu, J., Davis, R. J. & Flavell, R. A. (1997) Proc. Natl. Acad. Sci. USA 94, 3004-3009.
21. Gupta, S., Campbell, D., Derijard, B. & Davis, R. J. (1995) Science 267, 389-393.
22. Chen, Y. R., Meyer, C. F. & Tan, T. H. (1996) J. Biol. Chem. 271, 631-634.
23. Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J. & Greenberg, M. E. (1995) Science 270, 1326-1331.
24. Fuchs, S. Y., Dolan, L., Davis, R. J. & Ronai, Z. (1996) Oncogene 13, 1531-1535.
25. Fuchs, S. Y., Xie, B., Adler, V., Fried, V. A., Davis, R. J. & Ronai, Z. (1997) J. Biol. Chem. 272, 32163-32166.
26. Musti, A. M., Treier, M. & Bohmann, D. (1997) Science 275, 400-402.
27. Maltzman, W. & Czyzyk, L. (1984) Mol. Cell. Biol. 4, 1689-1694.
28. Haupt, Y., Maya, R. Kazaz, A. & Oren, M. (1997) Nature (London) 387, 296-299.
29. Fuchs, S. Y., Adler, A., Buschmann, T., Yin, Z., Wu, X., Jones, S. N. & Ronai, Z. (1998) Genes Dev., in press.
30. Hupp, T. R., Sparks, A. & Lane, D. P. (1995) Cell 83, 237-245.
31. Livingstone, L. R., White, A., Sprouse, J., Livanos, E., Jacks, T. & Tisty, T. D. (1992) Cell 70, 923-935.
32. Pear, W. S., Nolan, G. P., Scott, M. L. & Baltimore, D. (1993) Proc. Natl. Acad. Sci. USA 90, 8392-8396.
33. Wu, X. & Levine, A. J. (1994) Proc. Natl. Acad. Sci. USA 91, 3602-3606.
34. Kallunki, T., Su, B., Tsigelny, I., Sluss, H. K., Derijard, B., Moore, G., Davis, R. & Karin, M. (1994) Genes Dev 8, 2996-3007.
35. Cho, Y. Gorina, S., Jeffrey. P. D. & Pavletich, N. P. (1994) Science 265, 346-355.
36. Ripoll, D. & Scheraga, H. A. (1988) Biopolymers 27, 1283-1303.
37. Dauber-Osguthorpe, P., Roberts, V. A., Osguthorpe, D. J., Wolff, J., Genest, M. & Hagler, A. T. (1988) Proteins 4, 31-47.
38. Kubbutat, M. H., Jones, S. N. & Vousden, K. H. (1997) Nature (London) 387, 299-303.
39. Fuchs, S. Y., Adler, V., Buschmann, T., Wu, X. & Ronai, Z. (1998) Oncogene, in press.
40. Lee, F. S., Hagler, J., Chen, Z. J. & Maniatis, T. (1997) Cell 88, 213-222.
41. Mayo, M. W., Wang, C. Y., Cogswell, P. C., Rogers-Graham, K. S., Lowe, S. W., Der, C. J. & Baldwin, A. S., Jr. (1997) Science 278, 1812-1815.
42. Fanger, G. R., Johnson, N, L. & Johnson, G. L. (1997) EMBO J. 16, 4961-4972.
43. Siow, Y. L., Kalmar, G. B., Sanghera, J. S., Tai, G., Oh, S. S. & Pelech, S. L. (1997) J. Biol. Chem. 272, 7586-7594.
44. Adler, V., Pincus, M. R., Brandt-Rauf, P. W. & Ronai Z. (1995) Proc. Natl. Acad. Sci. USA 92, 10585-10589.
45. Adler, V., Pincus, M. R., Polotskaya, A., Montano, X., Friedman, F. K. & Ronai, Z. (1996) J. Biol. Chem. 271, 23304-23309.
46. Maki, C. G. & Howley, P. M. (1997) Mol. Cell. Biol. 17, 355-363.