The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2

EMBO Journal

Volumn 17, Issue 17, 1998, Pages 5001-5014

  Stott, Francesca J ^a   Bates, Stewart ^b   James, Marion C ^a   McConnell, Beth B ^a   Starborg, Maria ^a   Brookes, Sharon ^a   Palmero, Ignacio ^a,c   Ryan, Kevin ^b   Hara, Eiji ^a,d   Vousden, Karen H ^b   Peters, Gordon ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^d KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Cell cycle; MDM2; p53 response; Replicative senescence; Tumour suppression

Indexed keywords

CYCLIN DEPENDENT KINASE; DNA; PROTEIN P21; PROTEIN P53; VIRUS PROTEIN;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DNA DAMAGE; FEEDBACK SYSTEM; GENE ACTIVATION; GENE LOCUS; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR SUPPRESSOR GENE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; CELL CYCLE; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEEDBACK; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53;

HUMAN PAPILLOMA VIRUS; PAPILLOMAVIRUS;

EID: 0032169516     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.17.5001     Document Type: Article

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