-
1
-
-
0031929684
-
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein
-
Alcalay, M., Tomassoni, L., Colombo, E., Stoldt, S., Grignani, F., Fagioli, M., Szekely, L., Helin, K., and Pelicci, P.G. (1998).The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein. Mol. Cell. Biol. 18, 1084-1093.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1084-1093
-
-
Alcalay, M.1
Tomassoni, L.2
Colombo, E.3
Stoldt, S.4
Grignani, F.5
Fagioli, M.6
Szekely, L.7
Helin, K.8
Pelicci, P.G.9
-
2
-
-
0032504783
-
ARF links the tumor suppressors RB and p53
-
ARF links the tumor suppressors RB and p53. Nature 395, 124-125.
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clark, P.3
Stott, F.4
Peters, G.5
Ludwig, R.6
Vousden, K.H.7
-
3
-
-
0032146795
-
ARF tumor suppressor
-
ARF tumor suppressor. Genes Dev. 12, 2434-2442.
-
(1998)
Genes Dev.
, vol.12
, pp. 2434-2442
-
-
De Stanchina, E.1
McCurrach, M.E.2
Zindy, F.3
Shieh, S.-Y.4
Ferbeyre, G.5
Samuelson, A.V.6
Prives, C.7
Roussel, M.F.8
Sherr, C.J.9
Lowe, S.W.10
-
4
-
-
0028179010
-
A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein
-
Dyck, U.A., Maul, G.G., Miller, W.H., Chen, J.D., Kakizuka, A., and Evans, R.M. (1994). A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell 76, 333-343.
-
(1994)
Cell
, vol.76
, pp. 333-343
-
-
Dyck, U.A.1
Maul, G.G.2
Miller, W.H.3
Chen, J.D.4
Kakizuka, A.5
Evans, R.M.6
-
5
-
-
0030899774
-
The CDK2A (p16) gene and human cancer
-
Foulkes, W.D., Flanders, T.Y., Pollock, P.M., and Hayward, N.K. (1997). The CDK2A (p16) gene and human cancer. Mol. Med. 3, 5-20.
-
(1997)
Mol. Med.
, vol.3
, pp. 5-20
-
-
Foulkes, W.D.1
Flanders, T.Y.2
Pollock, P.M.3
Hayward, N.K.4
-
6
-
-
0031724593
-
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
-
Freedman, D.A., and Levine, A.J. (1998). Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol. Cell. Biol. 18, 7288-7293.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7288-7293
-
-
Freedman, D.A.1
Levine, A.J.2
-
7
-
-
0032185124
-
p300/MDM2 complexes participate in MDM2-mediated p53 degradation
-
Grossman, S.R., Perez, M., Kung, A.L., Joseph, M., Mansur, C., Xiao, Z.X., Kumar, S., Howley, P.M., and Linvingston, D.M. (1998). p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol. Cell 2, 405-415.
-
(1998)
Mol. Cell
, vol.2
, pp. 405-415
-
-
Grossman, S.R.1
Perez, M.2
Kung, A.L.3
Joseph, M.4
Mansur, C.5
Xiao, Z.X.6
Kumar, S.7
Howley, P.M.8
Linvingston, D.M.9
-
8
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., Maya, R., Kazaz, A., and Oren, M. (1997). Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
9
-
-
0033082231
-
RB regulates the stability and the apoptotic function of p53 via MDM2
-
Hsieh, J.-K., Chan, F.S.G., O'Connor, D.J., Mittnacht, S., Zhong, S., and Lu, X. (1999). RB regulates the stability and the apoptotic function of p53 via MDM2. Mol. Cell 3, 181-193.
-
(1999)
Mol. Cell
, vol.3
, pp. 181-193
-
-
Hsieh, J.-K.1
Chan, F.S.G.2
O'Connor, D.J.3
Mittnacht, S.4
Zhong, S.5
Lu, X.6
-
10
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Kamb, A., Gruis, N.A., Weaver-Feldhaus, J., Liu, Q., Harshman, K., Tavitgian, S.V., Stockert, E., Day, R.S., Johnson, B.E., and Skolnick, M.H. (1994). A cell cycle regulator potentially involved in genesis of many tumor types. Science 264, 436-440.
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavitgian, S.V.6
Stockert, E.7
Day, R.S.8
Johnson, B.E.9
Skolnick, M.H.10
-
11
-
-
0030728468
-
ARF
-
ARF. Cell 91, 649-659.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
12
-
-
0032493350
-
Functional and physical interaction of the ARF tumor suppressor with p53 and MDM2
-
Kamijo, T., Weber, J.D., Zambetti, G., Zindy, F., Roussel, M., and Sherr, C.J. (1998). Functional and physical interaction of the ARF tumor suppressor with p53 and MDM2. Proc. Natl. Acad. Sci. USA 95, 8292-8297.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.5
Sherr, C.J.6
-
13
-
-
0029052951
-
Tumor-derived p16 alleles encoding proteins defective in cell-cycle inhibition
-
Koh, J., Enders, G.H., Dynlacht, B.D., and Harlow, E. (1995). Tumor-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature 375, 506-510.
-
(1995)
Nature
, vol.375
, pp. 506-510
-
-
Koh, J.1
Enders, G.H.2
Dynlacht, B.D.3
Harlow, E.4
-
14
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M.H.G., Jones, S.N., and Vousden, K.H. (1997). Regulation of p53 stability by Mdm2. Nature 387, 299-303.
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.G.1
Jones, S.N.2
Vousden, K.H.3
-
15
-
-
0032574737
-
Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body
-
Lamorte, V.J., Dyck, J.A., Ochs, R.L., and Evans, R.M. (1998). Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body. Proc. Natl. Acad. Sci. USA 95, 4991-4996.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4991-4996
-
-
Lamorte, V.J.1
Dyck, J.A.2
Ochs, R.L.3
Evans, R.M.4
-
16
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine, A. J. (1997). p53, the cellular gatekeeper for growth and division. Cell 88, 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
17
-
-
0028275733
-
Deletion of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
-
Nobori, T., Mlura, K., Wu, D.J., Lois, A., Takabayashi, K., and Carson, D.A. (1994). Deletion of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 368, 753-756.
-
(1994)
Nature
, vol.368
, pp. 753-756
-
-
Nobori, T.1
Mlura, K.2
Wu, D.J.3
Lois, A.4
Takabayashi, K.5
Carson, D.A.6
-
19
-
-
0032549704
-
The INK4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz, J., Schreiber-Agus, N., Liegeois, N.J., Silverman, A., Alland, L., Chin, L., Potes, J., Chen, K., Orlow, I., and DePinho, R.A. (1998). The INK4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92, 713-723.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
DePinho, R.A.10
-
20
-
-
0032475878
-
Signaling to p53: Breaking the MDM2-p53 circuit
-
Prives, C. (1998). Signaling to p53: breaking the MDM2-p53 circuit. Cell 95, 5-8.
-
(1998)
Cell
, vol.95
, pp. 5-8
-
-
Prives, C.1
-
21
-
-
0029587551
-
Alterative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle, D.E., Zindy, F., Ashmun, R., and Sherr, C.J. (1995). Alterative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 83, 993-1000.
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.3
Sherr, C.J.4
-
23
-
-
0032518917
-
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
-
Roth, J., Dobbelstein, M., Freedman, D.A., Shenk, T., and Levine, A.J. (1998). Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J. 17, 554-564.
-
(1998)
EMBO J.
, vol.17
, pp. 554-564
-
-
Roth, J.1
Dobbelstein, M.2
Freedman, D.A.3
Shenk, T.4
Levine, A.J.5
-
25
-
-
0027769876
-
A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano, M., Hannon, G.J., and Beach, D. (1993). A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366, 704-707.
-
(1993)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
26
-
-
0032191393
-
Tumor surveillance via the ARF-p53 pathway
-
Sherr, C.J. (1998). Tumor surveillance via the ARF-p53 pathway. Genes Dev. 12, 2984-2991.
-
(1998)
Genes Dev.
, vol.12
, pp. 2984-2991
-
-
Sherr, C.J.1
-
27
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh, S.-Y., Ikeda, M., Taya, Y., and Prives, C. (1997). DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.-Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
28
-
-
0033559256
-
A leucine-rich export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
-
Stommel, J.M., Marchenko, N.D., Jimenez, G.S., Moll, U.M., Hope, T.J., and Wahl, G.M. (1999). A leucine-rich export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J. 18, 1660-1672.
-
(1999)
EMBO J.
, vol.18
, pp. 1660-1672
-
-
Stommel, J.M.1
Marchenko, N.D.2
Jimenez, G.S.3
Moll, U.M.4
Hope, T.J.5
Wahl, G.M.6
-
29
-
-
0032169516
-
ARF, participates in a regulatory feedback loop with p53 and MDM2
-
ARF, participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 17, 5001-5014.
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
30
-
-
0028158682
-
Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells
-
Weis, K., Rambaud, S., Lavau, C., Jansen, J., Carvalho, T., Carmo-Fonseca, M., Lamond, A., and Dejean, A. (1994). Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells. Cell 76, 345-356.
-
(1994)
Cell
, vol.76
, pp. 345-356
-
-
Weis, K.1
Rambaud, S.2
Lavau, C.3
Jansen, J.4
Carvalho, T.5
Carmo-Fonseca, M.6
Lamond, A.7
Dejean, A.8
-
31
-
-
0029028354
-
Interaction between the retinoblastima protein and the oncoprotein MDM2
-
Xiao, Z., Chen, J., Levine, A.J., Modjtahedi, N., Xing, J., Sellers, W.R., and Livingston, D.M. (1995). Interaction between the retinoblastima protein and the oncoprotein MDM2. Nature 375, 694-698.
-
(1995)
Nature
, vol.375
, pp. 694-698
-
-
Xiao, Z.1
Chen, J.2
Levine, A.J.3
Modjtahedi, N.4
Xing, J.5
Sellers, W.R.6
Livingston, D.M.7
-
32
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang, Y., Xiong, Y., and Yarbrough, W.G. (1998). ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92, 725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
33
-
-
0032145569
-
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
-
Zindy, F., Eischen, C.M., Randle, D.H., Kamijo, T., Cleveland, J.L., Sherr, C.J., and Roussel, M.F. (1998). Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev. 12, 2424-2433.
-
(1998)
Genes Dev.
, vol.12
, pp. 2424-2433
-
-
Zindy, F.1
Eischen, C.M.2
Randle, D.H.3
Kamijo, T.4
Cleveland, J.L.5
Sherr, C.J.6
Roussel, M.F.7
|