-
2
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni J.F., Jr.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
Friend, S.H.11
-
7
-
-
0028176453
-
Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene
-
(1994)
Oncogene
, vol.9
, pp. 603-609
-
-
Purdie, C.A.1
Harrison, D.J.2
Peter, A.3
Dobbie, L.4
White, S.5
Howie, S.E.6
Salter, D.M.7
Bird, C.C.8
Wyllie, A.H.9
Hooper, M.L.10
Clarke, A.R.11
-
13
-
-
0033119627
-
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2
-
(1999)
EMBO J.
, vol.18
, pp. 1805-1814
-
-
Unger, T.1
Juven-Gershon, T.2
Moallem, E.3
Berger, M.4
Vogt Sionov, R.5
Lozano, G.6
Oren, M.7
Haupt, Y.8
-
15
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Leigeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
20
-
-
0031593685
-
Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression
-
(1998)
Nat. Med.
, vol.4
, pp. 835-838
-
-
Roperch, J.P.1
Alvaro, V.2
Prieur, S.3
Tuynder, M.4
Nemani, M.5
Lethrosne, F.6
Piouffre, L.7
Gendron, M.C.8
Israeli, D.9
Dausset, J.10
Oren, M.11
Amson, R.12
Telerman, A.13
-
22
-
-
0032127463
-
p53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53
-
(1998)
EMBO J.
, vol.17
, pp. 3587-3596
-
-
Gottlieb, E.1
Oren, M.2
-
28
-
-
0028882764
-
Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate
-
(1995)
J. Neurosci.
, vol.15
, pp. 6377-6388
-
-
Dugan, L.L.1
Sensi, S.L.2
Canzoniero, L.M.3
Handran, S.D.4
Rothman, S.M.5
Lin, T.S.6
Goldberg, M.P.7
Choi, D.W.8
-
29
-
-
0029064518
-
Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
-
(1995)
J. Neurosci.
, vol.15
, pp. 3318-3327
-
-
Reynolds, I.J.1
Hastings, T.G.2
-
31
-
-
0030004746
-
DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures
-
(1996)
J. Neurosci.
, vol.16
, pp. 2238-2250
-
-
Didier, M.1
Bursztajn, S.2
Adamec, E.3
Passani, L.4
Nixon, R.A.5
Coyle, J.T.6
Wei, J.Y.7
Berman, S.A.8
-
32
-
-
0029055808
-
Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus
-
(1995)
Cell
, vol.81
, pp. 1021-1029
-
-
Jayaraman, J.1
Prives, C.2
-
47
-
-
0026745610
-
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haas, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
48
-
-
0026760261
-
Production of the Alzheimer amyloid beta protein by normal proteolytic processing
-
(1992)
Science
, vol.258
, pp. 126-129
-
-
Shoji, M.1
Golde, T.E.2
Ghiso, J.3
Cheung, T.T.4
Estus, S.5
Shaffer, L.M.6
Cai, X.D.7
McKay, D.M.8
Tintner, R.9
Frangione, B.10
Younkin, S.G.11
-
50
-
-
0032192481
-
Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation
-
(1998)
Neuron
, vol.21
, pp. 799-811
-
-
Jiang, Y.H.1
Armstrong, D.2
Albrecht, U.3
Atkins, C.M.4
Noebels, J.L.5
Eichele, G.6
Sweatt, J.A.7
Beaudet, A.L.8
-
54
-
-
0033525538
-
Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6039-6042
-
-
Chen, R.W.1
Chuang, D.M.2
-
55
-
-
0033556356
-
A role for MAPK/ERK in sympathetic neuron survival: Protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside
-
(1999)
J. Neurosci.
, vol.19
, pp. 664-673
-
-
Anderson, C.N.G.1
Tolkovsky, A.M.2
-
56
-
-
0031017148
-
p53 expression induces apoptosis in hippocampal pyramidal neuron cultures
-
(1997)
J. Neurosci.
, vol.17
, pp. 1397-1405
-
-
Jordan, J.1
Galindo, M.F.2
Prehn, J.H.3
Weichselbaum, R.R.4
Beckett, M.5
Ghadge, G.D.6
Roos, R.P.7
Leiden, J.M.8
Miller, R.J.9
-
62
-
-
0030840777
-
p53-knockoutmice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies
-
(1997)
J. Neurochem.
, vol.69
, pp. 780-790
-
-
Hirata, H.1
Cadet, J.L.2
-
64
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.1
Chang, C.Y.2
Hu, N.3
Wang, Y.C.4
Lai, C.C.5
Herrup, K.6
Lee, W.H.7
Bradley, A.8
-
65
-
-
0029910628
-
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
-
(1996)
EMBO J.
, vol.15
, pp. 6178-6188
-
-
Macleod, K.F.1
Hu, Y.2
Jacks, T.3
-
71
-
-
0032534625
-
Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 721-733
-
-
Johnson, M.D.1
Xiang, H.2
London, S.3
Kinoshita, Y.4
Knudson, M.5
Mayberg, M.6
Korsmeyer, S.J.7
Morrison, R.S.8
-
75
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.-X.10
Chen, W.11
Zhai, P.12
Surfit, R.L.13
Siddique, T.14
-
77
-
-
0031051485
-
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
-
(1997)
Neuron
, vol.18
, pp. 327-338
-
-
Bruijn, L.I.1
Becher, M.W.2
Lee, M.K.3
Anderson, K.L.4
Jenkins, N.A.5
Copeland, N.G.6
Sisodia, S.S.7
Rothstein, J.D.8
Borchelt, D.R.9
Price, D.L.10
Cleveland, D.W.11
-
91
-
-
0029125857
-
Aging, energy, and oxidative stress in neurodegenerative diseases
-
(1995)
Ann. Neurol.
, vol.38
, pp. 357-366
-
-
Beal, M.F.1
-
93
-
-
9544246860
-
Mitochondrial permeability transition is a central coordinating event of apoptosis
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1155-1160
-
-
Marchetti, P.1
Castedo, M.2
Susin, S.A.3
Zamzami, N.4
Hirsch, T.5
Macho, A.6
Haeffner, A.7
Hirsch, F.8
Geuskens, M.9
Kroemer, G.10
-
96
-
-
0034681136
-
Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 889-894
-
-
Chong, M.J.1
Murray, M.R.2
Gosink, E.C.3
Russell, H.R.4
Srinivasan, A.5
Kapsetaki, M.6
Korsmeyer, S.J.7
McKinnon, P.J.8
-
103
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
113
-
-
0027050648
-
Wild-type p53 binds to the TATA-binding protein and represses transcription
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 12028-12032
-
-
Seto, E.1
Usheva, A.2
Zambetti, G.P.3
Momand, J.4
Horikoshi, N.5
Weinmann, R.6
Levine, A.J.7
Shenk, T.8
-
114
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
115
-
-
0033552638
-
Twenty years of p53 research: Structural and functional aspects of the p53 protein
-
(1999)
Oncogene
, vol.18
, pp. 7621-7636
-
-
May, P.1
May, E.2
-
116
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
-
118
-
-
0030689782
-
The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo
-
(1997)
Oncogene
, vol.15
, pp. 1527-1534
-
-
Reinke, V.1
Lozano, G.2
-
119
-
-
7344231094
-
Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment
-
(1998)
Cell Death Differ.
, vol.5
, pp. 584-591
-
-
Kobayashi, T.1
Ruan, S.2
Jabbur, J.R.3
Consoli, U.4
Clodi, K.5
Shiku, H.6
Owen-Schaub, L.B.7
Andreef, M.8
Reed, J.C.9
Zhang, W.10
-
124
-
-
0033229866
-
p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
-
(1999)
EMBO J.
, vol.18
, pp. 6027-6036
-
-
Li, P.F.1
Dietz, R.2
von Harsdorf, R.3
-
138
-
-
0032566649
-
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
-
(1998)
Science
, vol.281
, pp. 2027-2031
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Jurgensmeier, J.M.4
Susin, S.A.5
Vieira, H.L.6
Prevost, M.C.7
Xie, Z.8
Matsuyama, S.9
Reed, J.C.10
Kroemer, G.11
-
141
-
-
0034710303
-
p38 MAP kinase mediates Bax translocation in nitric oxide-induced apoptosis in neurons
-
(2000)
J. Cell. Biol.
, vol.150
, pp. 335-348
-
-
Ghatan, S.1
Larner, S.2
Kinoshita, Y.3
Hetman, M.4
Patel, L.5
Xia, Z.6
Youle, R.J.7
Morrison, R.S.8
-
149
-
-
0034654623
-
PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family
-
(2000)
Genes Dev.
, vol.14
, pp. 704-718
-
-
Attardi, L.D.1
Reczek, E.E.2
Cosmas, C.3
Demicco, E.G.4
McCurrach, M.E.5
Lowe, S.W.6
Jacks, T.7
-
159
-
-
0033052291
-
Necrosis and apoptosis after retinal ischemia: Involvement of NMDA-mediated excitotoxicity and p53
-
(1999)
Invest. Ophthalmol. Vis. Sci.
, vol.40
, pp. 713-720
-
-
Joo, C.K.1
Choi, J.S.2
Ko, H.W.3
Park, K.Y.4
Sohn, S.5
Chun, M.H.6
Oh, Y.J.7
Gwag, B.J.8
-
167
-
-
0027940391
-
Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins
-
(1994)
Neurosci. Lett.
, vol.182
, pp. 112-114
-
-
Davies, A.M.1
Rosenthal, A.2
|