p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons

Neuroscience Letters

Volumn 203, Issue 1, 1996, Pages 1-4

  Enokido, Yasushi ^a   Araki, Toshiyuki ^a   Aizawa, Shinichi ^b   Hatanaka, Hiroshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

DNA damage; Gene knockout; Oxygen radical; Programmed cell death

Indexed keywords

CYTARABINE; OXYGEN RADICAL;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL CULTURE; CEREBELLUM; CONTROLLED STUDY; DNA DAMAGE; GRANULE CELL; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0030031650     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(95)12247-8     Document Type: Article

References (20)

1. Chopp, M., Li, Y. Zhang, Z.G. and Freytag, S.O., p53 expression in brain after middle cerebral artery occlusion in the rat, Biochem. Biophys. Res. Commun., 182 (1992) 1201-1207.
2. Clarke, A.R., Purdie, C.A., Harrison, D.J., Morris, R.G., Bird, C.C., Hooper, M.L. and Wyllie, A.H., Thymocyte apoptosis induced by p53-dependent and independent pathway, Nature, 362 (1993) 849-852.
3. Dessi, F., Pollard H., Moreau, J., Ben-Ari, Y. and Charriaut-Marlangue, C., Cytosine arabinoside induces apoptosis in cerebellar neurons in culture, J. Neurochem., 64 (1995) 1980-1987.
4. Dipasquale, B., Marini, A.M. and Youle, R.J., Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons, Biochem. Biophys. Res. Commun., 181 (1991) 1442-1448.
5. D'Mello, S.R., Galli, C., Ciotti, T. and Calissano, P., Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP, Proc. Natl. Acad. Sci. USA, 90 (1993) 10989-10993.
6. El-Deiry, W.S., Tokino, T., Veculescu, V.E., Levy, D.B., Parsons, R., Trent, J., Lin, U., Mercer, W.E., Kinzler, K.W. and Vogelstein, B., WAFI, a potential mediator of p53 tumor suppression, Cell, 75 (1992) 817-825.
7. Freeman, R.S., Estus, S. and Johnson, Jr., E.M., Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of cyclin D1 during programmed cell death, Neuron, 12 (1994) 343-355.
8. Kubo, T., Nonomura, T., Enokido, Y. and Hatanaka, H., Brain-derived neurotrophic factor (BDNF) can prevent apoptosis of rat cerebellar granule neurons in culture, Dev. Brain Res., 85 (1995) 249-258.
9. Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A. and Jacks, T., p53 is required for radiation-induced apoptosis in mouse thymocyte, Nature, 362 (1993) 847-849.
10. Martin, D., Wallace, T. and Johnson, Jr., E.M., Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction, J. Neurosci., 10 (1990) 184-193.
11. Oppenheim, R.W., Cell death during development of the nervous system, Annu. Rev. Neurosci., 14 (1991) 453-501.
12. Raff, M.C., Barres, B.A., Burne, J.F., Coles, H.S., Ishizaki, Y. and Jacobson, M.D., Programmed cell death and the control of cell survival: lessons from the nervous system. Science, 262 (1993) 695-700.
13. Sakhi, S., Bruce, A., Sun, N., Tocco, G., Baudry, M. and Schreiber, S.S., p53 induction is associated with neuronal damage in the central nervous system, Proc. Natl. Acad. Sci. USA, 91 (1994) 7525-7529.
14. Shaw, P., Bovey, R., Tardy, S., Sahli, R., Sordat, B. and Costa, J., Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line, Proc. Natl. Acad. Sci. USA, 89 (1992) 4495-4499.
15. Tomkins, C.E., Edwards, S.N. and Tolkovsky, A.M., Apoptosis is induced in post-mitotic rat sympathetic neurons by arabinoside and topoisomerase inhibitors in the presence of NGF, J. Cell Sci., 107 (1994) 1499-1507.
16. Tsukada, T., Tomooka, Y., Takai, S., Ueda, Y., Nishikawa, S., Yagi, T., Tokunaga, T., Takeda, N., Suda, Y., Abe, S., Matsuo, I., Ikawa, Y. and Aizawa, S., Enhanced proliferative potential in culture of cells from p53-deficient mice, Oncogene, 8 (1993) 3313-3322.
17. Vaus, D.L., Toward an understanding of the molecular mechanisms of physiological cell death, Proc. Natl. Acad. Sci. USA, 90 (1993) 786-789.
18. Wyllie, A.H., Morris, R.G., Smith, A.L. and Dunlop, D., Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis, J. Pathol., 142 (1984) 67-77.
19. Wood, K.A. and Youle, R.J., The role of free radicals and p53 in neuron apoptosis in vivo, J. Neurosci., 15 (1995) 5851-5857.
20. Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A. and Oren, M., Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6, Nature, 352 (1991) 345-347.