Inhibition of presenilin I expression is promoted by p53 and p21(WAF-1) and results in apoptosis and tumor suppression

Nature Medicine

Volumn 4, Issue 7, 1998, Pages 835-838

  Roperch, Jean Pierre ^a   Alvaro, Véronique ^a   Prieur, Sylvie ^a   Tuynder, Marcel ^b   Nemani, Mona ^a   Lethrosne, Florence ^a   Piouffre, Laurence ^a   Gendron, Marie Claude ^c   Israeli, David ^d   Dausset, Jean ^a   Oren, Moshe ^d   Amson, Robert ^a   Telerman, Adam ^a  

^a FONDATION JEAN DAUSSET CEPH   (France)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c INSTITUT JACQUES MONOD   (France)

^d Weizmann Instruite of Science ^*  (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

PRESENILIN 1; PROTEIN P21; PROTEIN P53; CDKN1A PROTEIN, HUMAN; CDKN1A PROTEIN, MOUSE; COMPLEMENTARY DNA; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; MEMBRANE PROTEIN; PSEN1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CANCER INHIBITION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE MUTATION; MOLECULAR CLONING; NERVE DEGENERATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA, COMPLEMENTARY; GENE EXPRESSION; HUMANS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; PRESENILIN-1; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031593685     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0798-835     Document Type: Article

References (20)

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