메뉴 건너뛰기




Volumn 17, Issue 13, 1998, Pages 3587-3596

p53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53

Author keywords

Apoptosis; Caspase; Interleukin 3; p53; Retinoblastoma

Indexed keywords

INTERLEUKIN 3; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 0032127463     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.13.3587     Document Type: Article
Times cited : (76)

References (84)
  • 1
    • 0028879323 scopus 로고
    • Regulation of P53-mediated apoptosis and cell cycle arrest by steel factor
    • Abrahamson, J.L.A., Lee, J.M. and Bernstein, A. (1995) Regulation of P53-mediated apoptosis and cell cycle arrest by steel factor. Mol. Cell Biol., 15, 6953-6960.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 6953-6960
    • Abrahamson, J.L.A.1    Lee, J.M.2    Bernstein, A.3
  • 2
    • 0029050533 scopus 로고
    • Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes and apoptosis
    • Almasan, A., Yin, Y.X., Kelly, R.E., Lee, E.Y.H.P., Bradley, A., Li, W.W., Bertino, J.R. and Wahl, G.M. (1995) Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes and apoptosis. Proc. Natl Acad. Sci. USA, 92, 5436-5440.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5436-5440
    • Almasan, A.1    Yin, Y.X.2    Kelly, R.E.3    Lee, E.Y.H.P.4    Bradley, A.5    Li, W.W.6    Bertino, J.R.7    Wahl, G.M.8
  • 3
    • 0030023846 scopus 로고    scopus 로고
    • Cleavage of retinoblastoma protein during apoptosis: An interleukin-1 beta-converting enzyme-like protease as candidate
    • An, B. and Dou, Q.P. (1996) Cleavage of retinoblastoma protein during apoptosis: an interleukin-1 beta-converting enzyme-like protease as candidate. Cancer Res., 56, 438-442.
    • (1996) Cancer Res. , vol.56 , pp. 438-442
    • An, B.1    Dou, Q.P.2
  • 4
    • 0030013337 scopus 로고    scopus 로고
    • Transcriptional activation by p53, but not induction of the P21 gene, is essential for oncogene-mediated apoptosis
    • Attardi, L.D., Lowe, S.W., Brugarolas, J. and Jacks, T. (1996) Transcriptional activation by p53, but not induction of the P21 gene, is essential for oncogene-mediated apoptosis. EMBO J., 15, 3693-3701.
    • (1996) EMBO J. , vol.15 , pp. 3693-3701
    • Attardi, L.D.1    Lowe, S.W.2    Brugarolas, J.3    Jacks, T.4
  • 5
    • 0029670589 scopus 로고    scopus 로고
    • P53 in signaling checkpoint arrest or apoptosis
    • Bates, S. and Vousden, K.H. (1996) P53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev., 6, 12-18.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 12-18
    • Bates, S.1    Vousden, K.H.2
  • 7
    • 0028900143 scopus 로고
    • Wild-type p53 modulates apoptosis of normal, IL-3 deprived, hematopoietic cells
    • Blandino, G., Scardigli, R., Rizzo, M.G., Crescenzi, M., Soddu, S. and Sacchi, A. (1995) Wild-type p53 modulates apoptosis of normal, IL-3 deprived, hematopoietic cells. Oncogene, 10, 731-737.
    • (1995) Oncogene , vol.10 , pp. 731-737
    • Blandino, G.1    Scardigli, R.2    Rizzo, M.G.3    Crescenzi, M.4    Soddu, S.5    Sacchi, A.6
  • 8
    • 0028070989 scopus 로고
    • P53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles, C., Helmberg, A. and Karin, M. (1994) p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature, 370, 220-223.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 9
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman, C.E., Gilmer, T.M., Coutts, S.B. and Kastan, M.B. (1995) Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev., 9, 600-611.
    • (1995) Genes Dev. , vol.9 , pp. 600-611
    • Canman, C.E.1    Gilmer, T.M.2    Coutts, S.B.3    Kastan, M.B.4
  • 10
    • 0030630531 scopus 로고    scopus 로고
    • Role of p53 in apoptosis
    • Canman, C.E. and Kastan, M.B. (1997) Role of p53 in apoptosis. Adv. Pharmacol., 41, 429-460.
    • (1997) Adv. Pharmacol. , vol.41 , pp. 429-460
    • Canman, C.E.1    Kastan, M.B.2
  • 11
    • 0030999788 scopus 로고    scopus 로고
    • Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding
    • Chen, W.D., Otterson, G.A., Lipkowitz, S., Khleif, S.N., Coxon, A.B. and Kaye, F.J. (1997) Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding. Oncogene, 14, 1243-1248.
    • (1997) Oncogene , vol.14 , pp. 1243-1248
    • Chen, W.D.1    Otterson, G.A.2    Lipkowitz, S.3    Khleif, S.N.4    Coxon, A.B.5    Kaye, F.J.6
  • 13
    • 9444242683 scopus 로고    scopus 로고
    • Shared role of the pRB-related p130 and p107 proteins in limb development
    • Cobrinik, D. et al. (1996) Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev., 10, 1633-1644.
    • (1996) Genes Dev. , vol.10 , pp. 1633-1644
    • Cobrinik, D.1
  • 14
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G.M. (1997) Caspases: the executioners of apoptosis. Biochem. J., 326, 1-16.
    • (1997) Biochem. J. , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 15
    • 0026731894 scopus 로고
    • Interleukin-3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents
    • Collins, M.K.L., Marvel, J., Malde, P. and Lopez-Rivas, A. (1992) Interleukin-3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents. J. Exp. Med., 176, 1043-1051.
    • (1992) J. Exp. Med. , vol.176 , pp. 1043-1051
    • Collins, M.K.L.1    Marvel, J.2    Malde, P.3    Lopez-Rivas, A.4
  • 16
    • 0027523439 scopus 로고
    • Human Papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequence necessary for transformation
    • Davies, R., Hicks, R., Crook, T., Morris, J. and Vousden, K. (1993) Human Papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequence necessary for transformation. J. Virol., 67, 2521-2528.
    • (1993) J. Virol. , vol.67 , pp. 2521-2528
    • Davies, R.1    Hicks, R.2    Crook, T.3    Morris, J.4    Vousden, K.5
  • 17
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
    • Debbas, M. and White, E. (1993) Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev., 7, 546-554.
    • (1993) Genes Dev. , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 18
    • 0024321239 scopus 로고
    • A point mutational analysis of human Papillomavirus type 16 E7 protein
    • Edmonds, C. and Vousden, K.H. (1989) A point mutational analysis of human Papillomavirus type 16 E7 protein. J. Virol., 63, 2650-2656.
    • (1989) J. Virol. , vol.63 , pp. 2650-2656
    • Edmonds, C.1    Vousden, K.H.2
  • 19
    • 0029883399 scopus 로고    scopus 로고
    • The retinoblastoma gene product inhibits TGF-beta 1 induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells
    • Fan, G.S., Ma, X.M., Kren, B.T. and Steer, C.J. (1996) The retinoblastoma gene product inhibits TGF-beta 1 induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells. Oncogene, 12, 1909-1919.
    • (1996) Oncogene , vol.12 , pp. 1909-1919
    • Fan, G.S.1    Ma, X.M.2    Kren, B.T.3    Steer, C.J.4
  • 21
    • 0028071541 scopus 로고
    • The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice
    • Fromm, L., Shawlot, W., Gunning, K., Butel, J.S. and Overbeek, P.A., (1994) The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice. Mol. Cell Biol., 14, 6743-6754.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6743-6754
    • Fromm, L.1    Shawlot, W.2    Gunning, K.3    Butel, J.S.4    Overbeek, P.A.5
  • 22
    • 0030584079 scopus 로고    scopus 로고
    • Apoptosis meets signal transduction: Elimination of a BAD influence
    • Gajewski, T.F. and Thompson, C.B. (1996) Apoptosis meets signal transduction: elimination of a BAD influence. Cell, 87, 589-592.
    • (1996) Cell , vol.87 , pp. 589-592
    • Gajewski, T.F.1    Thompson, C.B.2
  • 23
    • 0030902111 scopus 로고    scopus 로고
    • P21 (Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells
    • Gorospe, M., Cirielli, C., Wang, X.T., Seth, P., Capogrossi M.C. and Holbrook, N.J. (1997) p21 (Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells. Oncogene, 14, 929-935.
    • (1997) Oncogene , vol.14 , pp. 929-935
    • Gorospe, M.1    Cirielli, C.2    Wang, X.T.3    Seth, P.4    Capogrossi, M.C.5    Holbrook, N.J.6
  • 24
    • 0028294898 scopus 로고
    • Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal
    • Gottlieb, E., Haffner, R., von-Ruden, T., Wagner, E.F. and Oren, M. (1994) Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO J., 13, 1368-1374.
    • (1994) EMBO J. , vol.13 , pp. 1368-1374
    • Gottlieb, E.1    Haffner, R.2    Von-Ruden, T.3    Wagner, E.F.4    Oren, M.5
  • 25
    • 0029823623 scopus 로고    scopus 로고
    • Relationship of sequence-specific transactivation and p53-regulated apoptosis in interleukin 3-dependent hematopoietic cells
    • Gottlieb, E., Lindner, S. and Oren, M. (1996) Relationship of sequence-specific transactivation and p53-regulated apoptosis in interleukin 3-dependent hematopoietic cells. Cell Growth Differ., 7, 301-310.
    • (1996) Cell Growth Differ. , vol.7 , pp. 301-310
    • Gottlieb, E.1    Lindner, S.2    Oren, M.3
  • 26
    • 0029980043 scopus 로고    scopus 로고
    • p53 in growth control and neoplasia. Biochim
    • Gottlieb, T.M. and Oren, M. (1996) p53 in growth control and neoplasia. Biochim. Biophys. Acta - Rev. Cancer, 1287, 77-102.
    • (1996) Biophys. Acta - Rev. Cancer , vol.1287 , pp. 77-102
    • Gottlieb, T.M.1    Oren, M.2
  • 28
    • 0031051042 scopus 로고    scopus 로고
    • p53; from inductive signal to cellular effect. Curr
    • Hansen, R. and Oren, M. (1997) p53; from inductive signal to cellular effect. Curr. Opin. Genet. Dev., 7, 46-51.
    • (1997) Opin. Genet. Dev. , vol.7 , pp. 46-51
    • Hansen, R.1    Oren, M.2
  • 29
    • 0029610153 scopus 로고
    • The transforming oncoproteins determine the mechanism by which p53 suppresses cell transformation: PRb-mediated growth arrest or apoptosis
    • Hansen, R., Reddel, R. and Braithwaite, A. (1995) The transforming oncoproteins determine the mechanism by which p53 suppresses cell transformation: pRb-mediated growth arrest or apoptosis. Oncogene, 11, 2535-2545.
    • (1995) Oncogene , vol.11 , pp. 2535-2545
    • Hansen, R.1    Reddel, R.2    Braithwaite, A.3
  • 30
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by trans-activation-deficient p53
    • Haupt, Y., Rowan, S., Shaulian, E., Vousden, K.H. and Oren, M. (1995a) Induction of apoptosis in HeLa cells by trans-activation-deficient p53. Genes Dev., 9, 2170-2183.
    • (1995) Genes Dev. , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.H.4    Oren, M.5
  • 31
    • 0028999429 scopus 로고
    • p53-mediated apoptosis in HeLa cells can be overcome by excess pRB
    • Haupt, Y., Rowan, S. and Oren, M. (1995b) p53-mediated apoptosis in HeLa cells can be overcome by excess pRB. Oncogene, 10, 1563-1571.
    • (1995) Oncogene , vol.10 , pp. 1563-1571
    • Haupt, Y.1    Rowan, S.2    Oren, M.3
  • 32
    • 0030991235 scopus 로고    scopus 로고
    • The retinoblastoma protein: A master regulator of cell cycle, differentiation and apoptosis
    • Herwig, S. and Strauss, M. (1997) The retinoblastoma protein: a master regulator of cell cycle, differentiation and apoptosis. Eur. J. Biochem., 246, 581-601.
    • (1997) Eur. J. Biochem. , vol.246 , pp. 581-601
    • Herwig, S.1    Strauss, M.2
  • 34
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • Howes, K.A., Ransom, L.N., Papermaster, D.S., Lasudry, J.G.H., Albert, D.M. and Windle, J.J. (1994) Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev., 8, 1300-1310.
    • (1994) Genes Dev. , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, L.N.2    Papermaster, D.S.3    Lasudry, J.G.H.4    Albert, D.M.5    Windle, J.J.6
  • 35
    • 0021941624 scopus 로고
    • Biochemical and biological properties of interleukin-3: A lymphokine mediating the differentiation of lineage of cells that includes prothymocytes and mastlike cells
    • Ihle, J.N. (1984) Biochemical and biological properties of interleukin-3: a lymphokine mediating the differentiation of lineage of cells that includes prothymocytes and mastlike cells. Contemp. Topic. Mol. Immunol., 10, 93-119.
    • (1984) Contemp. Topic. Mol. Immunol. , vol.10 , pp. 93-119
    • Ihle, J.N.1
  • 36
    • 0029028352 scopus 로고
    • Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo
    • Ishioka, C., Englert, C., Winge, P. Yan, Y.X., Engelstein, M. and Friend, S.H. (1995) Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian cell assays in vivo. Oncogene, 10, 1485-1492.
    • (1995) Oncogene , vol.10 , pp. 1485-1492
    • Ishioka, C.1    Englert, C.2    Winge, P.3    Yan, Y.X.4    Engelstein, M.5    Friend, S.H.6
  • 38
    • 0030462563 scopus 로고    scopus 로고
    • Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis
    • Janicke, R.U., Walker, P.A., Lin, X.Y. and Porter, A.G. (1996) Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. EMBO J., 15, 6969-6978.
    • (1996) EMBO J. , vol.15 , pp. 6969-6978
    • Janicke, R.U.1    Walker, P.A.2    Lin, X.Y.3    Porter, A.G.4
  • 39
    • 0023872192 scopus 로고
    • Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors
    • Karasuyama, H. and Melchers, F. (1988) Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol., 18, 97-104.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 97-104
    • Karasuyama, H.1    Melchers, F.2
  • 40
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko, L.J. and Prives, C. (1996) p53: puzzle and paradigm. Genes Dev., 10, 1054-1072.
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 41
    • 0027109075 scopus 로고
    • P53, guardian of the genome
    • Lane, D.P. (1992) p53, guardian of the genome. Nature, 358, 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 42
    • 0026744563 scopus 로고
    • Mice deficient for Rb Are nonviable and show defects in neurogenesis and haematopoiesis
    • Lee, E.Y.H.P., Chang, C.Y., Hu, N.P., Wang, Y.C.J., Lai, C.C., Herrup, K., Lee, W.H. and Bradley, A. (1992) Mice deficient for Rb Are nonviable and show defects in neurogenesis and haematopoiesis. Nature, 359, 288-294.
    • (1992) Nature , vol.359 , pp. 288-294
    • Lee, E.Y.H.P.1    Chang, C.Y.2    Hu, N.P.3    Wang, Y.C.J.4    Lai, C.C.5    Herrup, K.6    Lee, W.H.7    Bradley, A.8
  • 44
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A.J. (1997) p53, the cellular gatekeeper for growth and division. Cell, 88, 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 45
    • 0028882315 scopus 로고
    • Cytokines inhibit p53-mediated apoptosis but not p53-mediated G (1) arrest
    • Lin, Y.P. and Benchimol, S. (1995) Cytokines inhibit p53-mediated apoptosis but not p53-mediated G (1) arrest. Mol. Cell Biol, 15, 6045-6054.
    • (1995) Mol. Cell Biol , vol.15 , pp. 6045-6054
    • Lin, Y.P.1    Benchimol, S.2
  • 46
    • 0027283604 scopus 로고
    • Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents
    • Lotem, J. and Sachs, L. (1993) Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents. Blood, 82, 1092-1096.
    • (1993) Blood , vol.82 , pp. 1092-1096
    • Lotem, J.1    Sachs, L.2
  • 47
    • 0030750581 scopus 로고    scopus 로고
    • Cytokine suppression of protease activation in wild-type p53-dependent and p53-independent apoptosis
    • Lotem, J. and Sachs, L. (1997) Cytokine suppression of protease activation in wild-type p53-dependent and p53-independent apoptosis. Proc. Natl Acad. Sci. USA, 94, 9349-9353.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 9349-9353
    • Lotem, J.1    Sachs, L.2
  • 48
    • 0029910628 scopus 로고    scopus 로고
    • Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
    • Macleod, K.F. Hu, Y.W. and Jacks, T. (1996) Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J., 15, 6178-6188.
    • (1996) EMBO J. , vol.15 , pp. 6178-6188
    • Macleod, K.F.1    Hu, Y.W.2    Jacks, T.3
  • 49
    • 0029912856 scopus 로고    scopus 로고
    • The human retinoblastoma gene product suppresses ceramide-induced apoptosis in human bladder tumor cells
    • McConkey, D.J., Goodrich, D., Bucana, C. and Klostergaard, J. (1996) The human retinoblastoma gene product suppresses ceramide-induced apoptosis in human bladder tumor cells. Oncogene, 13, 1693-1700.
    • (1996) Oncogene , vol.13 , pp. 1693-1700
    • McConkey, D.J.1    Goodrich, D.2    Bucana, C.3    Klostergaard, J.4
  • 50
    • 0031080248 scopus 로고    scopus 로고
    • The role of the caspase family of cysteine proteases in apoptosis
    • Miller, D.K. (1997) The role of the caspase family of cysteine proteases in apoptosis. Semin. Immunol., 9, 35-49.
    • (1997) Semin. Immunol. , vol.9 , pp. 35-49
    • Miller, D.K.1
  • 51
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S.D., Williams, B.O., Jacks, T. and Depinho, R.A. (1994) p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature, 371, 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    Depinho, R.A.4
  • 52
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern, J.P. and Land, H. (1990) Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acid Res., 18, 3587-3596.
    • (1990) Nucleic Acid Res. , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 53
    • 0025959660 scopus 로고
    • BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of philadelphia chromosome-positive human leukemias
    • Muller, A.J., Young, J.C., Pendergast, A.-M., Pondel, M., Landau, N.R., Littman, D.R. and Witte, O.N. (1991) BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of philadelphia chromosome-positive human leukemias. Mol. Cell Biol., 11, 1785-1792.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 1785-1792
    • Muller, A.J.1    Young, J.C.2    Pendergast, A.-M.3    Pondel, M.4    Landau, N.R.5    Littman, D.R.6    Witte, O.N.7
  • 54
    • 0030828981 scopus 로고    scopus 로고
    • Requirement of the caspase-3/CPP32 protease cascade for apoptotic death following cytokine deprivation in hematopoietic cells
    • Ohta, T., Kinoshita, T., Naito, M. Nozaki, T., Masutani, M., Tsuruo, T. and Miyajima, A. (1997) Requirement of the caspase-3/CPP32 protease cascade for apoptotic death following cytokine deprivation in hematopoietic cells. J. Biol. Chem., 272, 23111-23116.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23111-23116
    • Ohta, T.1    Kinoshita, T.2    Naito, M.3    Nozaki, T.4    Masutani, M.5    Tsuruo, T.6    Miyajima, A.7
  • 55
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
    • Pan, H. and Griep, A.E. (1994) Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev., 8, 1285-1299.
    • (1994) Genes Dev. , vol.8 , pp. 1285-1299
    • Pan, H.1    Griep, A.E.2
  • 56
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear, W.S., Nolan, G.P., Scott, M.L. and Baltimore, D. (1993) Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl Acad. Sci. USA, 90, 8392-8396.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 57
    • 0029916932 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells
    • Poluha, W., Poluha, D.K., Chang, B.C., Crosbie, N.E., Schonhoff, C.M., Kilpatrick, D.L. and Ross, A.H. (1996) The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells. Mol. Cell Biol., 16, 1335-1341.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 1335-1341
    • Poluha, W.1    Poluha, D.K.2    Chang, B.C.3    Crosbie, N.E.4    Schonhoff, C.M.5    Kilpatrick, D.L.6    Ross, A.H.7
  • 58
    • 0029811984 scopus 로고    scopus 로고
    • Genetic determinants of p53-induced apoptosis and growth arrest
    • Polyak, K., Waldman, T., He, T.C., Kinzler, K.W. and Vogelstein, B. (1996) Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev., 10, 1945-1952.
    • (1996) Genes Dev. , vol.10 , pp. 1945-1952
    • Polyak, K.1    Waldman, T.2    He, T.C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 60
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin, X.Q., Livingston, D.M., Kaelin, W.G. and Adams, P.D. (1994) Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl Acad. Sci. USA, 91, 10918-10922.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.Q.1    Livingston, D.M.2    Kaelin, W.G.3    Adams, P.D.4
  • 61
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the bcl-2 family
    • Reed, J.C. (1997) Double identity for proteins of the bcl-2 family. Nature, 387, 773-776.
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 62
    • 0029143395 scopus 로고
    • Essential role for p53-mediated transcription in E1A-induced apoptosis
    • Sabbatini, P., Lin, J.Y., Levine, A.J. and White, E. (1995) Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev., 9, 2184-2192.
    • (1995) Genes Dev. , vol.9 , pp. 2184-2192
    • Sabbatini, P.1    Lin, J.Y.2    Levine, A.J.3    White, E.4
  • 63
    • 0030997647 scopus 로고    scopus 로고
    • Interleukin-1b converting enzyme-like protease are essential for p53-mediated transcriptionally dependent apoptosis
    • Sabbatini, P., Han, J., Chiou, S.-K., Nicholson, D.W. and White, E. (1997) Interleukin-1b converting enzyme-like protease are essential for p53-mediated transcriptionally dependent apoptosis. Cell. Growth Diff., 8, 643-653.
    • (1997) Cell. Growth Diff. , vol.8 , pp. 643-653
    • Sabbatini, P.1    Han, J.2    Chiou, S.-K.3    Nicholson, D.W.4    White, E.5
  • 64
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen, G.S. and Dixit, V.M. (1997) Caspases: intracellular signaling by proteolysis. Cell, 91, 443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 65
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan, B. and Lee, W.H. (1994) Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell Biol., 14, 8166-8173.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.H.2
  • 66
    • 0028575705 scopus 로고
    • Relief of p53-mediated transcriptional repression by the adenovirus E1B 19 kDa protein or the cellular bcl-2 protein
    • Shen, Y.Q. and Shenk, T. (1994) Relief of p53-mediated transcriptional repression by the adenovirus E1B 19 kDa protein or the cellular bcl-2 protein. Proc. Natl Acad. Sci. USA, 91, 8940-8944.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 8940-8944
    • Shen, Y.Q.1    Shenk, T.2
  • 67
    • 0028914946 scopus 로고
    • Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins
    • Slack, R.S., Skerjanc, I.S., Lach, B., Craig, J., Jardine, K. and McBurney, M.W. (1995) Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins. J. Cell Biol., 129, 779-788.
    • (1995) J. Cell Biol. , vol.129 , pp. 779-788
    • Slack, R.S.1    Skerjanc, I.S.2    Lach, B.3    Craig, J.4    Jardine, K.5    McBurney, M.W.6
  • 68
    • 0032031417 scopus 로고    scopus 로고
    • The caspase-RB connection in cell death
    • Tan, X. and Wang, J.Y. (1998) The caspase-RB connection in cell death. Trends Cell Biol., 8, 116-120.
    • (1998) Trends Cell Biol. , vol.8 , pp. 116-120
    • Tan, X.1    Wang, J.Y.2
  • 69
    • 0030899360 scopus 로고    scopus 로고
    • Degradation of retinoblastoma protein in tumor necrosis factor- And CD95-induced cell death
    • Tan, X.Q., Martin, S.J., Green, D.R. and Wang, J.Y.J. (1997) Degradation of retinoblastoma protein in tumor necrosis factor-and CD95-induced cell death. J. Biol. Chem., 272, 9613-9616.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9613-9616
    • Tan, X.Q.1    Martin, S.J.2    Green, D.R.3    Wang, J.Y.J.4
  • 70
    • 0028034199 scopus 로고
    • Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21 (waf1/cip1)
    • Wagner, A.J., Kokontis, J.M. and Hay, N. (1994) Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21 (waf1/cip1). Genes Dev., 8, 2817-2830.
    • (1994) Genes Dev. , vol.8 , pp. 2817-2830
    • Wagner, A.J.1    Kokontis, J.M.2    Hay, N.3
  • 71
    • 0345498292 scopus 로고    scopus 로고
    • Bcl-2 targets the protein kinase raf-1 to mitochondria
    • Wang, H.G., Rapp, U.R. and Reed, J.C. (1996) Bcl-2 targets the protein kinase raf-1 to mitochondria. Cell, 87, 629-638.
    • (1996) Cell , vol.87 , pp. 629-638
    • Wang, H.G.1    Rapp, U.R.2    Reed, J.C.3
  • 72
    • 0031050236 scopus 로고    scopus 로고
    • Rb functions to inhibit apoptosis during myocyte differentiation
    • Wang, J., Guo, K., Wills, K.N. and Walsh, K. (1997) Rb functions to inhibit apoptosis during myocyte differentiation. Cancer Res., 57, 351-354.
    • (1997) Cancer Res. , vol.57 , pp. 351-354
    • Wang, J.1    Guo, K.2    Wills, K.N.3    Walsh, K.4
  • 73
    • 0029996726 scopus 로고    scopus 로고
    • Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation
    • Wang, J. and Walsh, K. (1996) Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science, 273, 359-361.
    • (1996) Science , vol.273 , pp. 359-361
    • Wang, J.1    Walsh, K.2
  • 74
    • 0031052563 scopus 로고    scopus 로고
    • Retinoblastoma protein in growth suppression and death protection
    • Wang, J.Y.J. (1997) Retinoblastoma protein in growth suppression and death protection. Curr. Opin. Genet. Dev., 7, 39-45.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 39-45
    • Wang, J.Y.J.1
  • 75
    • 0030865388 scopus 로고    scopus 로고
    • Induction of apoptosis in Mv1Lu cells by expression of competitive RB1 mutants
    • Whitaker, L.L. and Hansen, M.F. (1997) Induction of apoptosis in Mv1Lu cells by expression of competitive RB1 mutants. Oncogene, 15, 1069-1077.
    • (1997) Oncogene , vol.15 , pp. 1069-1077
    • Whitaker, L.L.1    Hansen, M.F.2
  • 76
    • 0028087776 scopus 로고
    • p53, guardian of Rb
    • White, E. (1994) p53, guardian of Rb. Nature, 371, 21-22.
    • (1994) Nature , vol.371 , pp. 21-22
    • White, E.1
  • 77
    • 0028222124 scopus 로고
    • P53 and E2F-1 cooperate to mediate apoptosis
    • Wu, X.W. and Levine, A.J. (1994) P53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl Acad. Sci. USA., 91, 3602-3606.
    • (1994) Proc. Natl Acad. Sci. USA. , vol.91 , pp. 3602-3606
    • Wu, X.W.1    Levine, A.J.2
  • 78
    • 0031577506 scopus 로고    scopus 로고
    • Apoptosis - Clues in the p53 murder mystery
    • Wyllie, A. (1997) Apoptosis - clues in the p53 murder mystery. Nature, 389, 237-238.
    • (1997) Nature , vol.389 , pp. 237-238
    • Wyllie, A.1
  • 81
    • 0029585933 scopus 로고
    • Transcriptional activation plays a role in the induction of apoptosis by transiently transfected wild-type p53
    • Yonish-Rouach, E., Deguin, V., Zaitchouk, T., Breugnot, C., Mishal, Z., Jenkins, J.R. and May, E. (1995) Transcriptional activation plays a role in the induction of apoptosis by transiently transfected wild-type p53. Oncogene, 11, 2197-2205.
    • (1995) Oncogene , vol.11 , pp. 2197-2205
    • Yonish-Rouach, E.1    Deguin, V.2    Zaitchouk, T.3    Breugnot, C.4    Mishal, Z.5    Jenkins, J.R.6    May, E.7
  • 82
    • 0029819994 scopus 로고    scopus 로고
    • pRb controls proliferation differentiation and death of skeletal muscle cells and other lineages during embryogenesis
    • Zacksenhaus, E., Jiang, Z., Chung, D., Marth, J.D., Phillips, R.A. and Gallie, B.L. (1996) pRb controls proliferation differentiation and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev., 10, 3051-3064.
    • (1996) Genes Dev. , vol.10 , pp. 3051-3064
    • Zacksenhaus, E.1    Jiang, Z.2    Chung, D.3    Marth, J.D.4    Phillips, R.A.5    Gallie, B.L.6
  • 83
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X (L)
    • Zha, J.P., Harada, H., Yang, E., Jockel, J. and Korsmeyer, S.J. (1996) Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X (L). Cell, 87, 619-628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.P.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 84
    • 0028266265 scopus 로고
    • Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells
    • Zhu, Y.M., Bradbury, D.A. and Russell, N.H. (1994) Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells. Br. J. Cancer, 69, 468-472.
    • (1994) Br. J. Cancer , vol.69 , pp. 468-472
    • Zhu, Y.M.1    Bradbury, D.A.2    Russell, N.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.