DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures

Journal of Neuroscience

Volumn 16, Issue 7, 1996, Pages 2238-2250

  Didier, Michel ^a,c   Bursztajn, Sherry ^a,c   Adamec, Emil ^a,c   Passani, Lucius ^b,c   Nixon, Ralph A ^a,c   Coyle, Joseph T ^b,c   Wei, Jeanne Y ^c   Berman, Stephen A ^a,c  

^a MCLEAN HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

apoptosis; cerebellar granule cells; DNA damage; excitotoxicity; glutamate transporter; necrosis; nick translation; NMDA receptor; primary cultures; TUNEL labeling

Indexed keywords

2 AMINOADIPIC ACID; CELL NUCLEUS DNA; DIZOCILPINE; DNA FRAGMENT; DOUBLE STRANDED DNA; EXCITOTOXIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SINGLE STRANDED DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA DEGRADATION; DNA NICK TRANSLATION; DNA STRAND BREAKAGE; GRANULE CELL; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; SOUTHERN BLOTTING;

EID: 0030004746     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-07-02238.1996     Document Type: Article

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