메뉴 건너뛰기




Volumn 8, Issue 6, 1997, Pages 643-653

Interleukin 1β converting enzyme-like proteases are essential for p53- mediated transcriptionally dependent apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; LAMIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN P53; PROTEINASE; VIRUS PROTEIN;

EID: 0030997647     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (59)

References (95)
  • 1
    • 0029670265 scopus 로고    scopus 로고
    • ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis
    • Nicholson, D. W. ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis. Nat. Biotech., 14: 297-301, 1996.
    • (1996) Nat. Biotech. , vol.14 , pp. 297-301
    • Nicholson, D.W.1
  • 2
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Washington DC
    • Thompson, C. B. Apoptosis in the pathogenesis and treatment of disease. Science (Washington DC), 267: 1456-1462, 1995.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 3
    • 0027225887 scopus 로고
    • Regulation of apoptosis by the transforming genes of the DNA tumor virus adenovirus
    • White, E. Regulation of apoptosis by the transforming genes of the DNA tumor virus adenovirus. Proc. Soc. Exp. Biol. Med., 204: 30-39, 1993.
    • (1993) Proc. Soc. Exp. Biol. Med. , vol.204 , pp. 30-39
    • White, E.1
  • 4
    • 0003031285 scopus 로고
    • Regulation of apoptosis by human adenoviruses
    • D. Tomei and F. Cope (eds.), Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
    • White, E., and Gooding, L. R. Regulation of apoptosis by human adenoviruses. In: D. Tomei and F. Cope (eds.), Apoptosis: The Molecular Basis for Cell Death II, pp. 111-141. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1994.
    • (1994) Apoptosis: The Molecular Basis for Cell Death II , pp. 111-141
    • White, E.1    Gooding, L.R.2
  • 7
    • 0026639932 scopus 로고
    • The adenovirus E1A proteins induce apoptosis which is inhibited by the E1B 19K and Bcl-2 proteins
    • Rao, L., Debbas, M., Sabbatini, P., Hockenbery, D., Korsmeyer, S., and White, E. The adenovirus E1A proteins induce apoptosis which is inhibited by the E1B 19K and Bcl-2 proteins. Proc. Natl. Acad. Sci. USA, 89: 7742-7746, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7742-7746
    • Rao, L.1    Debbas, M.2    Sabbatini, P.3    Hockenbery, D.4    Korsmeyer, S.5    White, E.6
  • 8
    • 0029595337 scopus 로고
    • c-myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms
    • Sakamuro, D., Eviner, V., Elliot, K. J., Showe, L., White, E., and Pendergast, G. C. c-myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms. Oncogene, 11: 2411-2418, 1995.
    • (1995) Oncogene , vol.11 , pp. 2411-2418
    • Sakamuro, D.1    Eviner, V.2    Elliot, K.J.3    Showe, L.4    White, E.5    Pendergast, G.C.6
  • 9
    • 0028034199 scopus 로고
    • Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1
    • Wagner, A. J., Kokontis, J. M., and Hay, N. Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. Genes Dev., 8: 2817-2830, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 2817-2830
    • Wagner, A.J.1    Kokontis, J.M.2    Hay, N.3
  • 10
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A., and Oren, M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature (Lond.), 352: 345-347, 1991.
    • (1991) Nature (Lond.) , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 13
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., and Jacks, T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature (Lond.), 362: 847-849, 1993.
    • (1993) Nature (Lond.) , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 14
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74: 957-967, 1993.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 15
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie, A. H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature (Lond.), 284: 555-556, 1980.
    • (1980) Nature (Lond.) , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 16
    • 0026530847 scopus 로고
    • Bcl-2 gene: Current relevance to clinical oncology
    • Brada, M. Bcl-2 gene: current relevance to clinical oncology. Eur. J. Cancer, 28: 270-272, 1992.
    • (1992) Eur. J. Cancer , vol.28 , pp. 270-272
    • Brada, M.1
  • 17
    • 0026053958 scopus 로고
    • Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)
    • McDonnell, T. J., and Korsmeyer, S. J. Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature (Lond.), 349: 254-256, 1991.
    • (1991) Nature (Lond.) , vol.349 , pp. 254-256
    • McDonnell, T.J.1    Korsmeyer, S.J.2
  • 18
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B
    • Debbas, M., and White, E. Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B. Genes Dev., 7: 546-554, 1993.
    • (1993) Genes Dev. , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 20
    • 0025887476 scopus 로고
    • Wild-type p53 can down-modulate the activity of various promoters
    • Ginsberg, D., Mechta, F., Yaniv, M., and Oren, M. Wild-type p53 can down-modulate the activity of various promoters. Proc. Natl. Acad. Sci. USA, 88: 9979-9983, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9979-9983
    • Ginsberg, D.1    Mechta, F.2    Yaniv, M.3    Oren, M.4
  • 21
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by transactivation-deficient p53
    • Haupt, Y., Rowan, S., Shaulian, E., Vousden, K., and Oren, M. Induction of apoptosis in HeLa cells by transactivation-deficient p53. Genes Dev., 9: 2170-2183, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.4    Oren, M.5
  • 22
    • 0026642078 scopus 로고
    • Inhibition of viral and cellular promoters by human wild-type p53
    • Subler, M. A., Martin, D. W., and Deb, S. Inhibition of viral and cellular promoters by human wild-type p53. J. Virol., 66: 4757-4762, 1992.
    • (1992) J. Virol. , vol.66 , pp. 4757-4762
    • Subler, M.A.1    Martin, D.W.2    Deb, S.3
  • 23
    • 0026702212 scopus 로고
    • Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element
    • Zambetti, G. P., Bargonetti, J., Walker, K., Prives, C., and Levine, A. J. Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. Genes Dev., 6: 1143-1152, 1992.
    • (1992) Genes Dev. , vol.6 , pp. 1143-1152
    • Zambetti, G.P.1    Bargonetti, J.2    Walker, K.3    Prives, C.4    Levine, A.J.5
  • 24
    • 0028070989 scopus 로고
    • p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles, C., Helmberg, A., and Karin, M. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature (Lond.), 370: 220-223, 1994.
    • (1994) Nature (Lond.) , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 26
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • White, E. Life, death, and the pursuit of apoptosis. Genes Dev., 10: 1-15, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 27
    • 0030013337 scopus 로고    scopus 로고
    • Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
    • Attardi, L. D., Lowe, S. W., Brugarolas, J., and Jacks, T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J., 15: 3693-3701, 1996.
    • (1996) EMBO J. , vol.15 , pp. 3693-3701
    • Attardi, L.D.1    Lowe, S.W.2    Brugarolas, J.3    Jacks, T.4
  • 28
    • 0029585933 scopus 로고
    • Transcriptional activation plays a role in the induction of apoptosis by transiently-transfected wild-type p53
    • Yonish-Rouach, E., Deguin, V., Zaitchouk, T., Breugnot, C., Mishal, Z., Jenkins, J., and May, E. Transcriptional activation plays a role in the induction of apoptosis by transiently-transfected wild-type p53. Oncogene, 11: 2197-2205, 1995.
    • (1995) Oncogene , vol.11 , pp. 2197-2205
    • Yonish-Rouach, E.1    Deguin, V.2    Zaitchouk, T.3    Breugnot, C.4    Mishal, Z.5    Jenkins, J.6    May, E.7
  • 29
    • 0029143395 scopus 로고
    • Essential role for p53-mediated transcription in E1A-induced apoptosis
    • Sabbatini, P., Lin, J., Levine, A. J., and White, E. Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev., 9: 2184-2192, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 2184-2192
    • Sabbatini, P.1    Lin, J.2    Levine, A.J.3    White, E.4
  • 30
    • 0029868112 scopus 로고    scopus 로고
    • The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein
    • Han, J., Sabbatini, P., Perez, D., Rao, L., Mohda, D., and White, E. The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein. Genes Dev., 10: 461-477, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 461-477
    • Han, J.1    Sabbatini, P.2    Perez, D.3    Rao, L.4    Mohda, D.5    White, E.6
  • 31
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai, Z. N., Millman, C. L., and Korsmeyer, S. J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell, 74: 609-619, 1993.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Millman, C.L.2    Korsmeyer, S.J.3
  • 32
    • 0028222955 scopus 로고
    • Bcl-2 blocks p53-dependent apoptosis
    • Chiou, S-K., Rao, L., and White, E. Bcl-2 blocks p53-dependent apoptosis. Mol. Cell. Biol., 14: 2556-2563, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2556-2563
    • Chiou, S.-K.1    Rao, L.2    White, E.3
  • 33
    • 0028847563 scopus 로고
    • Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein
    • Sabbatini, P., Chiou, S-K., Rao, L., and White, E. Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein. Mol. Cell. Biol., 15: 1060-1070, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1060-1070
    • Sabbatini, P.1    Chiou, S.-K.2    Rao, L.3    White, E.4
  • 34
    • 0029783722 scopus 로고    scopus 로고
    • A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
    • Friedlander, P., Haupt, Y., Prives, C., and Oren, M. A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol. Cell Biol., 16: 4961-4971, 1996.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4961-4971
    • Friedlander, P.1    Haupt, Y.2    Prives, C.3    Oren, M.4
  • 35
    • 0029742781 scopus 로고    scopus 로고
    • Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function
    • Ludwig, R. L., Bates, S., and Vousden, K. H. Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function. Mol. Cell. Biol., 16: 4952-4960, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4952-4960
    • Ludwig, R.L.1    Bates, S.2    Vousden, K.H.3
  • 37
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita, T., and Reed, J. C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell, 80: 293-299, 1995.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 38
    • 0030021748 scopus 로고    scopus 로고
    • Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant
    • Rowan, S., Ludwig, R. L., Haupt, Y., Bates, S., Lu, X., Oren, M., and Vousden, K. H. Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant. EMBO J., 15: 827-838, 1996.
    • (1996) EMBO J. , vol.15 , pp. 827-838
    • Rowan, S.1    Ludwig, R.L.2    Haupt, Y.3    Bates, S.4    Lu, X.5    Oren, M.6    Vousden, K.H.7
  • 39
    • 0029790857 scopus 로고    scopus 로고
    • Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K
    • Han, J., Sabbatini, P., and White, E. Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K. Mol. Cell. Biol., 16: 5857-5864, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5857-5864
    • Han, J.1    Sabbatini, P.2    White, E.3
  • 40
    • 0029058323 scopus 로고
    • The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis
    • Beidler, D. R., Tewari, M., Friesen, P. D., Poirier, G., and Dixit, V. M. The baculovirus p35 protein inhibits Fas-and tumor necrosis factor-induced apoptosis. J. Biol. Chem., 270: 16526-16528, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16526-16528
    • Beidler, D.R.1    Tewari, M.2    Friesen, P.D.3    Poirier, G.4    Dixit, V.M.5
  • 41
    • 0030021282 scopus 로고    scopus 로고
    • Cell killing by the Drosophila gene reaper
    • Washington DC
    • White, K., Tahaoglu, E., and Steller, H. Cell killing by the Drosophila gene reaper. Science (Washington DC), 271: 805-807, 1996.
    • (1996) Science , vol.271 , pp. 805-807
    • White, K.1    Tahaoglu, E.2    Steller, H.3
  • 42
    • 0029056059 scopus 로고
    • Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
    • Xue, D., and Horvitz, H. R. Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein. Nature (Lond.), 377: 248-251, 1995.
    • (1995) Nature (Lond.) , vol.377 , pp. 248-251
    • Xue, D.1    Horvitz, H.R.2
  • 43
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas-mediated apoptosis
    • Enari, M., Hug, H., and Nagata, S. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature (Lond.), 375: 78-81, 1995.
    • (1995) Nature (Lond.) , vol.375 , pp. 78-81
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 45
    • 0028873964 scopus 로고
    • Fas- and TNF-induced apoptosis is inhibited by the poxvirus crmA gene product
    • Tewari, M., and Dixit, V. M. Fas- and TNF-induced apoptosis is inhibited by the poxvirus crmA gene product. J. Biol. Chem., 270: 3255-3260, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3255-3260
    • Tewari, M.1    Dixit, V.M.2
  • 49
    • 0028102478 scopus 로고
    • Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature (Lond.), 371: 346-347, 1994.
    • (1994) Nature (Lond.) , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 51
    • 0030060075 scopus 로고    scopus 로고
    • Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER
    • Washington DC
    • Pronk, G. J., Ramer, K., Amiri, P., and Williams, L. T. Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science (Washington DC), 271: 808-810, 1996.
    • (1996) Science , vol.271 , pp. 808-810
    • Pronk, G.J.1    Ramer, K.2    Amiri, P.3    Williams, L.T.4
  • 52
    • 0030002801 scopus 로고    scopus 로고
    • Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32
    • Slee, E. A., Huijun, Z., Chow, S. C., MacFarlane, M., Nicholson, D. W., and Cohen, G. M. Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem. J., 315: 21-24, 1996.
    • (1996) Biochem. J. , vol.315 , pp. 21-24
    • Slee, E.A.1    Huijun, Z.2    Chow, S.C.3    MacFarlane, M.4    Nicholson, D.W.5    Cohen, G.M.6
  • 54
    • 0028841537 scopus 로고
    • An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells
    • Zhu, H., Fearnhead, H. O., and Cohen, G. M. An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells. FEBS Lett., 374: 303-308, 1995.
    • (1995) FEBS Lett. , vol.374 , pp. 303-308
    • Zhu, H.1    Fearnhead, H.O.2    Cohen, G.M.3
  • 55
    • 0029811984 scopus 로고    scopus 로고
    • Genetic determinants of p53-induced apoptosis and growth arrest
    • Polyak, K., Waldman, T., He, T-C., Kinzler, K. W., and Vogelstein, B. Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev., 10: 1945-1952, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 1945-1952
    • Polyak, K.1    Waldman, T.2    He, T.-C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 56
    • 0030465544 scopus 로고    scopus 로고
    • Lamin proteolysis facilitates nuclear events during apoptosis
    • Rao, L., Perez, D., and White, E. Lamin proteolysis facilitates nuclear events during apoptosis. J. Cell Biol., 135: 1441-1455, 1996.
    • (1996) J. Cell Biol. , vol.135 , pp. 1441-1455
    • Rao, L.1    Perez, D.2    White, E.3
  • 57
    • 0028303752 scopus 로고
    • Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
    • Lin, J., Chen, J., Elenbaas, B., and Levine, A. J. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. Genes Dev., 8: 1235-1246, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 1235-1246
    • Lin, J.1    Chen, J.2    Elenbaas, B.3    Levine, A.J.4
  • 58
    • 0028990125 scopus 로고
    • Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G., Salvesen, G. S., and Dixit, V. M. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell, 81: 801-809, 1995.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 59
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian Interleukin-1β-converting enzyme
    • Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian Interleukin-1β-converting enzyme. J. Biol. Chem., 269: 30761-30764, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.3
  • 63
    • 0026446686 scopus 로고
    • Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding
    • Shaulian, E., Zauberman, A., Ginsberg, D., and Oren, M. Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding. Mol. Cell. Biol., 12: 5581-5592, 1992.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5581-5592
    • Shaulian, E.1    Zauberman, A.2    Ginsberg, D.3    Oren, M.4
  • 64
    • 0028812606 scopus 로고
    • Bik1, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins
    • Boyd, J. M., Gallo, G. J., Elangovan, B., Houghton, A. B., Malstrom, S., Avery, B. J., Ebb, R. G., Subramanian, T., Chittenden, T., Lutz, R. J., and Chinnadurai, G. Bik1, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. Oncogene, 11: 1921-1928, 1995.
    • (1995) Oncogene , vol.11 , pp. 1921-1928
    • Boyd, J.M.1    Gallo, G.J.2    Elangovan, B.3    Houghton, A.B.4    Malstrom, S.5    Avery, B.J.6    Ebb, R.G.7    Subramanian, T.8    Chittenden, T.9    Lutz, R.J.10    Chinnadurai, G.11
  • 66
    • 0024382760 scopus 로고
    • The p53 proto-oncogene can act as a suppressor of transformation
    • Finlay, C. A., Hinds, P. W., and Levine, A. J. The p53 proto-oncogene can act as a suppressor of transformation. Cell, 57; 1083-1093, 1989.
    • (1989) Cell , vol.57 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 67
    • 0025964061 scopus 로고
    • Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein
    • Ginsberg, D., Michael-Michalovitz, D., Ginsberg, D., and Oren, M. Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein. Mol. Cell. Biol., 11: 582-585, 1991.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 582-585
    • Ginsberg, D.1    Michael-Michalovitz, D.2    Ginsberg, D.3    Oren, M.4
  • 69
    • 0026656853 scopus 로고
    • Wild-type p53 is a cell cycle checkpoint determinant following irradiation
    • Kuerbitz, S. J., Plunkett, B. S., Walsh, W. V., and Kastan, M. B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89: 7491-7495, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7491-7495
    • Kuerbitz, S.J.1    Plunkett, B.S.2    Walsh, W.V.3    Kastan, M.B.4
  • 71
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. The p21 cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell, 75: 805-816, 1993.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 73
    • 0025950667 scopus 로고
    • Programmed cell death in the immune system
    • Cohen, J. J. Programmed cell death in the immune system. Adv. Immunol., 50: 55-85, 1991.
    • (1991) Adv. Immunol. , vol.50 , pp. 55-85
    • Cohen, J.J.1
  • 74
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • DiLeonardo, A., Linke, S. P., Clarkin, K., and Wahl, G. A. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev., 8: 2540-2551, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 2540-2551
    • Dileonardo, A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.A.4
  • 75
    • 0029802591 scopus 로고    scopus 로고
    • p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • Chen, X., Ko, L. J., Jayaraman, L., and Prives, C. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev., 10: 2438-2451, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.J.2    Jayaraman, L.3    Prives, C.4
  • 76
    • 0028999429 scopus 로고
    • p53-mediated apoptosis in HeLa cells can be overcome by excess pRB
    • Haupt, Y., Rowan, S., and Oren, M. p53-mediated apoptosis in HeLa cells can be overcome by excess pRB. Oncogene, 10: 1563-1571, 1995.
    • (1995) Oncogene , vol.10 , pp. 1563-1571
    • Haupt, Y.1    Rowan, S.2    Oren, M.3
  • 77
    • 0029093605 scopus 로고
    • Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
    • Pan, H., and Griep, A. E. Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev., 9: 2157-2169, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 2157-2169
    • Pan, H.1    Griep, A.E.2
  • 78
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin, X-Q., Livingston, D. M., Kaelin, W. G., and Adams, P. D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA, 97: 10918-10922, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10918-10922
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin, W.G.3    Adams, P.D.4
  • 79
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan, B., and Lee, W. H. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol., 14: 8166-8173, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.H.2
  • 80
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • Wu, X., and Levine, A. J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA, 91: 3602-3606, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 81
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman, C., Gilmer, T. M., Coutts, S. B., and Kastan, M. B. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev., 9: 600-611, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 600-611
    • Canman, C.1    Gilmer, T.M.2    Coutts, S.B.3    Kastan, M.B.4
  • 83
    • 0030027151 scopus 로고    scopus 로고
    • Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase
    • Boulakia, C. A., Chen, G., Ng, F. W. H., Teodoro, J. G., Branton, P. E., Nicholson, D. W., Poirier, G. G., and Shore, G. C. Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase. Oncogene, 12: 529-535, 1996.
    • (1996) Oncogene , vol.12 , pp. 529-535
    • Boulakia, C.A.1    Chen, G.2    Ng, F.W.H.3    Teodoro, J.G.4    Branton, P.E.5    Nicholson, D.W.6    Poirier, G.G.7    Shore, G.C.8
  • 84
    • 0028059445 scopus 로고
    • Functional complementation of the adenovirus E1B 19K protein with Bcl-2 in the inhibition of apoptosis in infected cells
    • Chiou, S. K., Tseng, C. C., Rao, L., and White, E. Functional complementation of the adenovirus E1B 19K protein with Bcl-2 in the inhibition of apoptosis in infected cells. J. Virol., 68: 6553-6566, 1994.
    • (1994) J. Virol. , vol.68 , pp. 6553-6566
    • Chiou, S.K.1    Tseng, C.C.2    Rao, L.3    White, E.4
  • 85
    • 0030220462 scopus 로고    scopus 로고
    • Bcl-2 regulates activation of apoptotic proteases in a cell-free system
    • Cosulich, S. C., Green, S., and Clarke, P. R. Bcl-2 regulates activation of apoptotic proteases in a cell-free system. Curr. Biol., 6: 997-1005, 1996.
    • (1996) Curr. Biol. , vol.6 , pp. 997-1005
    • Cosulich, S.C.1    Green, S.2    Clarke, P.R.3
  • 87
    • 0029984098 scopus 로고    scopus 로고
    • Bcl-2 expression prevents activation of the ICE protease cascade
    • Shimizu, S., Eguchi, Y., Kamiike, W., Matsuda, H., and Tsujimoto, Y. Bcl-2 expression prevents activation of the ICE protease cascade. Oncogene, 12: 2251-2257, 1996.
    • (1996) Oncogene , vol.12 , pp. 2251-2257
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Matsuda, H.4    Tsujimoto, Y.5
  • 89
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
    • Enari, M., Talanian, R. V., Wong, W. W., and Nagata, S. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature (Lond.), 380: 723-726, 1996.
    • (1996) Nature (Lond.) , vol.380 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 90
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand, J., Zambetti, G. P., Olson, D. C., George, D., and Levine, A. J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69: 1237-1245, 1992.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 91
    • 0028834902 scopus 로고
    • Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
    • Jones, S. N., Roe, A. E., Donehower, L. A., and Bradley, A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature (Lond.), 378: 206-208, 1995.
    • (1995) Nature (Lond.) , vol.378 , pp. 206-208
    • Jones, S.N.1    Roe, A.E.2    Donehower, L.A.3    Bradley, A.4
  • 92
    • 0028823020 scopus 로고
    • Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
    • Montes de Oca Luna, R., Wagner, D. S., and Lozano, G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature (Lond.), 378: 203-206, 1995.
    • (1995) Nature (Lond.) , vol.378 , pp. 203-206
    • Montes De Oca Luna, R.1    Wagner, D.S.2    Lozano, G.3
  • 93
  • 94
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • Michalovitz, D., Halevy, O., and Oren, M. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell, 62: 671-681, 1990.
    • (1990) Cell , vol.62 , pp. 671-681
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3
  • 95
    • 0029063175 scopus 로고
    • Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest
    • Lin, H-J. L., Eivner, V., Prendergast, G. C., and White, E. Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest. Mol. Cell. Biol., 15: 4536-4544, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4536-4544
    • Lin, H.-J.L.1    Eivner, V.2    Prendergast, G.C.3    White, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.