Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons

Journal of Neuroscience

Volumn 19, Issue 18, 1999, Pages 7860-7869

  Cregan, Sean P ^a   MacLaurin, Jason G ^a   Craig, Constance G ^c   Robertson, George S ^b   Nicholson, Donald W ^b   Park, David S ^a   Slack, Ruth S ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^c Apoptogen Inc   (Canada)

Author keywords

Apoptosis; Bax; Caspase 3; Neurodegeneration; Neurons; p53

Indexed keywords

CASPASE 3; PROTEIN BAX; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE TARGETING; GRANULE CELL; MOUSE; NERVE CELL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 0033568860     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-18-07860.1999     Document Type: Article

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