Differential regulation of APP secretion by apolipoprotein E3 and E4

Annals of the New York Academy of Sciences

Volumn 777, Issue , 1996, Pages 322-326

  Wolozin, B L ^a   Basaric Keys, J ^a   Canter, R ^a   Li, Y ^a   Vanderputten, D ^a   Sunderland, T ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; NONHUMAN; PHEOCHROMOCYTOMA CELL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RAT;

ANIMALIA;

EID: 0029983524     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb34440.x     Document Type: Conference Paper

References (7)

1. STRITTMATTER, W., A. SAUNDERS, D. SCHMECHEL, M. PERICAK-VANCE, J. ENGHILD, et al. 1993. Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer's disease. Proc. Natl. Acad. Sci. USA 90:1977-1981.
2. CORDER, E., A. SAUNDERS, W. STRITTMATTER, D. SCHMECHEL, P. GASKELL, et al. 1993. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:921-923.
3. SCHMECHEL, D., A. SAUNDERS, W. STRITTMATTER, B. CRAIN, C. HULETTE, et al. 1993. Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:9649-9653.
4. STRITTMATTER, W., K. WEISGRABER, D. HUANG, L. DONG, G. SALVESON, et al. 1993. Binding of human apolipoprotein E to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:8098-8102.
5. MA, J., A. YEE, H. BREWER, S. DAS & H. POTTER. 1994. Amyloid-associated proteins alpha(1)-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments. Nature 372:92-94.
6. NITSCH, R., B. SLACK, R. WURTMAN & J. GROWDON. 1992. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258:304-307.
7. NATHAN, B., S. BELLOSTA, D. SANAN, K. WEISGRABER, R. MAHLEY, et al. 1994. Differential effects of apolipoprotein E3 and E4 on neuronal growth in vitro. Science 264:850-852.