Additive effects of basic fibroblast growth factor and phorbol ester on β-amyloid precursor protein expression and secretion

Neurochemistry International

Volumn 30, Issue 4-5, 1997, Pages 475-481

  Ringheim, Garth E ^a   Aschmies, Suzan ^a   Petko, Wayne ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BASIC FIBROBLAST GROWTH FACTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PROTEIN KINASE C;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION;

AMYLOID BETA-PROTEIN PRECURSOR; BLOTTING, WESTERN; CARCINOGENS; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLAST GROWTH FACTOR 2; HUMANS; NEUROBLASTOMA; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0031003537     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(96)00084-8     Document Type: Article

References (41)

1. Alstiel, L. D. and Sperber, K. (1991) Cytokines in Alzheimer's disease. Progr. Neurol. Psychopharmacol. Biol. Psychiatr. 15, 481-495.
2. Breen, K. C., Bruce, M. and Anderton, B. H. (1991) Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion. J. Neurosci. Res. 28, 90-100.
3. Bruel, A., Cherqui, G., Columelli, S., Margelin, D., Roudier, M., Sinet, P. M., Prieur, M., Perignon, J. L. and Delabar, J. (1991) Reduced protein kinase C activity in sporadic Alzheimer's disease fibroblasts. Neurosci. Lett. 133, 89-92.
4. Buxbaum, J. D., Gandy, S. E., Cicchetti, P., Ehrlich, M. E., Czernik, A. J., Fracasso, R. P., Ramabhadran, T. V., Unterbeck, A. J. and Greengard, P. (1990) Processing of Alzheimer β/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation. Proc. natn. Acad. Sci. U.S.A. 87, 6003-6006.
5. Buxbaum, J. D., Koo, E. H. and Greengard, P. (1993) Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide. Proc. natn. Acad. Sci. U.S.A. 90, 9150-9158.
6. Buxbaum, J. D., Oishi, M., Chen H, I., Pinkas-Kramarski, R., Jaffe, E. A., Gandy, S. E. and Greengard, P. (1992) Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alhzeimer b/A4 amyloid protein precursor. Proc. natn. Acad. Sci. U.S.A. 89, 10075-10078.
7. Cacabelos, R., Barquero, M., Garcia, P., Alvarez, X. A., Varela de Seijas, E. (1991) Cerebrospinal fluid interleukin-1 beta (IL-1 beta) in Alzheimer's disease and neurological disorders. Methods Fin. Exp. Clin. Pharmacol. 13, 455-458.
8. Caporaso, G. L., Gandy, S. E., Buxbaum, J. D., Ramabhadran, T. V. and Greengard, P. (1992) Protein phosphorylation regulates secretion of Alzheimer b/A4 amyloid precursor protein. Proc. natn. Acad. Sci. U.S.A. 89, 3055-3059.
9. Cotman, C. W., Mathews, D. A., Taylor, D. and Lynch, G. (1973) Synpatic rearrangement in the dentate gyrus: histochemical evidence of adjustments after lesions in immature and adult rats. Proc. natn. Acad. Sci. U.S.A. 70, 3473-3477.
10. de Sauvage, F. and Ocatave, J. (1989) A novel mRNA of the A4 amyloid precursor gene coding for a possible secreted protein. Science 245, 651-653.
11. Esch, F. S., Keim, P. S., Beattie, E. C., Blacher, R. W., Culwell, A. R., Oltersdore, T., McClure, D. and Ward, P. J. (1990) Cleavage of amyloid β peptide during constitutive processing of its precursor. Science 248, 1122-1124.
12. Golde, T. E., Estus, S., Usiak, M., Younkin, L. H. and Younkin, S. G. (1990) Expression of β amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR. Neuron 4, 253-267.
13. Gómez-Pinilla, K., Cummings, G. J. and Cotman, C. W. (1990) Induction of basic fibroblast growth factor in Alzheimer's disease pathology. NeuroReport 1, 211-214.
14. Gómez-Pinilla, F., Lee, J. W. and Cotman, C. W. (1992) Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesions and fimbria-fornix transection. J. Neurosci. 12, 345-355.
15. Griffin, W. S. T., Ling, S. L. C. White, C., MacLeod, V., Perrot, L. F., White III, C. L. and Araoz, C. (1989) Brain interleukin-1 and S-100 immunoreactivity are elevated in Down's syndrome and Alzheimer's disease. Proc. natn. Acad. Sci. U.S.A. 86, 7611-7615.
16. Hung, A. Y., Haass, C., Nitsch, R. M., Qiu, W. Q., Citron, M., Wurtman, R. J., Growden, J. H. and Selkoe, D. J. (1993) Activation of protein kinase C inhibits cellular production of the amyloid β-protein. J. biol. Chem. 268, 22959-22962.
17. Hyman, B. T., Van Hoesen, G. W., Damasio, A. R. and Barnes, C. L. (1984) Alzheimer's disease: cell-specific pathology isolates the hippocampal formation. Science 225, 1168-1170.
18. Jacobsen, J. S., Muenkel, H. A., Blume, A. J. and Vitek, M. P. (1991) A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs. Neurobiol. Aging 12, 573-583.
19. Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, M. J., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K. and Müller-Hill, B. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733-736.
20. Kitaguchi, N., Takahashi, Y., Tokashima, Y., Shioyari, S. and Ito, H. (1988) Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331, 530-532.
21. Klier, F. G., Cole, G., Stallcup, W. and Schubert, D. (1990) Amyloid β-protein precursor is associated with extracellular matrix. Brain Res. 515, 336-342.
22. König, G., Mönning, U., Czech, C., Prior, R., Banati, R., Schreiter-Gasser, U., Bauer, J., Masters, C. L. and Beyreuther, K. (1992) Identification and differential expression of a novel alternative splice isorform of the β/A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells. J. biol. Chem. 267, 10804-10809.
23. Koo, E. H. and Squazzo, S. L. (1994) Evidence that production and release of amyloid β-protein involves the endocytic pathway. J. biol. Chem. 269, 17386-17389.
24. Lahiri, D. K. and Nail, C. (1995) Promoter activity of the gene encoding the β-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1. Mol. Brain Res. 32, 233-240.
25. Masliah, E., Cole, G. M., Hanssen, L. A., Albright, T., Terry, R. D. and Saitoh, T. (1991) Protein kinase C alteration is an early biochemical marker in Alzheimer's disease. J. Neurosci. 11, 2759-2767.
26. Mattson, M., Cheng, B., Culwell, A., Esch, F., Lieverburg, I. and Rydel, R. (1993) Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the amyloid precursor protein. Neuron 10, 243-254.
27. Milward, E. A., Papadopoulos, R., Fuller, S. J., Moir, R. D., Small, D., Beyreuther, K. and Masters, C. (1992) The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron 9, 129-137.
28. Mori, F., Lai, C., Fusi, F. and Giacobini, E. (1995) Cholinesterase inhibitors increase secretion of APPs in rat brain cortex. Neuroreport 6, 633-636.
29. Nitsch, R. M., Farber, S. A., Growdon, J. H. and Wurtman, R. J. (1993) Release of amyloid β-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proc. natn Acad. Sci. U.S.A. 90, 5191-5193.
30. Ponte, P., Gonzalez-DeWhitt, P., Schilling, J., Miller, J., Hsu, D., Greenberg, B., Davis, K., Wallace, W., Lieberburg, I., Fuller, F. and Cordell, B. (1988) A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature 331, 525-532.
31. Qiu, W. Q., Ferreira, A., Miller, C., Koo, E. H. and Selkoe, D. J. (1995) Cell-surface β-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner. J. Neurosci. 15, 2157-2167.
32. Salbaum, J. M., Weidermann, A., Lemaire, H.-G., Masters, C. L. and Beyreuther, K. (1991) The promoter of Alzheimer's disease amyloid A4 precursor gene. EMBO J. 7, 2807-2813.
33. Schubert, D., LaCorbiere, M., Saitoh, T. and Cole, G. (1989) Characterization of an amyloid precursor protein that binds heparin and contains tyrosine sulfate. Proc. natn. Acad. Sci. U.S.A. 86, 2066-2069.
34. Schubert, D., Jin, L. W., Saitoh, T. and Cole, G. (1989) The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion. Neuron 3(6), 689-694.
35. Sisodia, S. and Price, D. L. (1990) Role of the β-amyloid protein in Alzheimer's disease. FASEB J. 9, 366-370.
36. 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients. Lab. Invest. 66, 223-230.
37. Stopa, E. G., Gonzalez, A.-M., Chorsky, R., Corona, R. J., Alvarej, J., Bird, E. D. and Baird, A. (1990) Basic fibroblast growth factor in Alzheimer's disease. Biochem. Biophys. Res. Commun. 171, 690-696.
38. Tanzi, R. E., McClatchey, A. I., Lampert, E. D., Vill-Komaroff, L., Gusella, J. F. and Neve, R. L. (1988) Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature 331, 528-530.
39. Trejo, J., Massamiri, T., Deng, T., Dewji, N. N., Bayney, R. M. and Brown, J. H. (1994) A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's β-amyloid precursor protein gene. J. biol. Chem. 269, 21682-21690.
40. Van Huynh, T., Cole, G., Katzman, R., Huang, K. and Saitoh, T. (1989) Reduced protein kinase C immunoreactivity and altered protein phosphorylation in Alzheimer's disease fibroblasts. Arch. Neurol. 46, 1195-1199.
41. Weidemann, A., König, G., Bunke, D., Fischer, P., Salbaum, J. M., Masters, C. L. and Beyreuther, K. (1989) Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57, 115-126.