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Volumn 1, Issue 1, 1997, Pages 47-57

Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; COMPLEMENTARY DNA; DNA BINDING PROTEIN; LUCIFERASE; MEMBRANE PROTEIN; METALLOPROTEINASE; NUCLEAR PROTEIN; PROTEINASE; SREBF1 PROTEIN, HUMAN; SREBP SITE 2 PROTEASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR;

EID: 0031301274     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80006-4     Document Type: Article
Times cited : (402)

References (47)
  • 2
    • 0028211009 scopus 로고
    • PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates
    • Barnes, W.M. (1994). PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates. Proc. Natl. Acad. Sci. USA 91, 2216-2220.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2216-2220
    • Barnes, W.M.1
  • 3
    • 0017894322 scopus 로고
    • Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase
    • Brown, M.S., Faust, J.R., Goldstein, J.L., Kaneko, I., and Endo, A. (1978). Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase. J. Biol. Chem. 253, 1121-1128.
    • (1978) J. Biol. Chem. , vol.253 , pp. 1121-1128
    • Brown, M.S.1    Faust, J.R.2    Goldstein, J.L.3    Kaneko, I.4    Endo, A.5
  • 4
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown, M.S., and Goldstein, J.L. (1997). The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89, 331-340.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 5
    • 15844418021 scopus 로고    scopus 로고
    • Complementation of mutation in acyl-CoA: Cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells
    • Cao, G., Goldstein, J.L., and Brown, M.S. (1996). Complementation of mutation in acyl-CoA: cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells. J. Biol. Chem. 271, 14642-14648.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14642-14648
    • Cao, G.1    Goldstein, J.L.2    Brown, M.S.3
  • 6
    • 0020420324 scopus 로고
    • Revertants of a Chinese hamster ovary cell mutant resistant to suppression by an analogue of cholesterol: Isolation and partial biochemical characterization
    • Chang, T.-Y. and Chang, C.C. Y. (1982). Revertants of a Chinese hamster ovary cell mutant resistant to suppression by an analogue of cholesterol: isolation and partial biochemical characterization. Biochemistry 21, 5316-5323.
    • (1982) Biochemistry , vol.21 , pp. 5316-5323
    • Chang, T.-Y.1    Chang, C.C.Y.2
  • 8
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Devereux, J., Haeberli, P., and Smithies, O. (1984). A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12, 387-395.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Devereux, J.1    Haeberli, P.2    Smithies, O.3
  • 9
    • 0030911517 scopus 로고    scopus 로고
    • Cleavage site for sterol-regulated protease localized to a Leu-Ser bond in lumenal loop of sterol regulatory element binding protein-2
    • Duncan, E.A., Brown, M.S., Goldstein, J.L., and Sakai, J. (1997). Cleavage site for sterol-regulated protease localized to a Leu-Ser bond in lumenal loop of sterol regulatory element binding protein-2. J. Biol. Chem. 272, 12778-12785.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12778-12785
    • Duncan, E.A.1    Brown, M.S.2    Goldstein, J.L.3    Sakai, J.4
  • 10
    • 0029744890 scopus 로고    scopus 로고
    • Synergistic binding of sterol regulatory element-binding protein and NF-Y to the farnesyl diphosphate synthase promoter is critical for sterol-regulated expression of the gene
    • Ericsson, J., Jackson, S.M., and Edwards, P.A. (1996). Synergistic binding of sterol regulatory element-binding protein and NF-Y to the farnesyl diphosphate synthase promoter is critical for sterol-regulated expression of the gene. J. Biol. Chem. 271, 24359-24364.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24359-24364
    • Ericsson, J.1    Jackson, S.M.2    Edwards, P.A.3
  • 11
    • 0027261368 scopus 로고
    • Loss of transcriptional activation of three sterol-regulated genes in mutant hamster cells
    • Evans, M.J., and Metherall, J.E. (1993). Loss of transcriptional activation of three sterol-regulated genes in mutant hamster cells. Mol. Cell. Biol. 13, 5175-5185.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5175-5185
    • Evans, M.J.1    Metherall, J.E.2
  • 13
    • 0020973547 scopus 로고
    • Receptor-mediated endocytosis of LDL in cultured cells
    • Goldstein, J.L., Basu, S.K., and Brown, M.S. (1983). Receptor-mediated endocytosis of LDL in cultured cells. Meth. Enzymol. 98, 241-260.
    • (1983) Meth. Enzymol. , vol.98 , pp. 241-260
    • Goldstein, J.L.1    Basu, S.K.2    Brown, M.S.3
  • 14
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein, J.L., and Brown, M.S. (1990). Regulation of the mevalonate pathway. Nature 343, 425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 16
    • 0028087833 scopus 로고
    • Somatic cell genetic biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression
    • Hasan, M.T., Chang, C.C.Y., and Chang, T.Y. (1994). Somatic cell genetic biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression. Somatic Cell Mol. Genet. 20, 183-194.
    • (1994) Somatic Cell Mol. Genet. , vol.20 , pp. 183-194
    • Hasan, M.T.1    Chang, C.C.Y.2    Chang, T.Y.3
  • 17
    • 0027941838 scopus 로고
    • Families of zinc metalloproteases
    • Hooper, N.M. (1994). Families of zinc metalloproteases. FEBS Lett. 354, 1-6.
    • (1994) FEBS Lett. , vol.354 , pp. 1-6
    • Hooper, N.M.1
  • 18
    • 0030298339 scopus 로고    scopus 로고
    • Sterol resistance in CHO cells traced to point mutation in SREBP cleavage activating protein (SCAP)
    • Hua, X., Nohturfft, A., Goldstein, J.L., and Brown, M.S. (1996a). Sterol resistance in CHO cells traced to point mutation in SREBP cleavage activating protein (SCAP). Cell 87, 415-426.
    • (1996) Cell , vol.87 , pp. 415-426
    • Hua, X.1    Nohturfft, A.2    Goldstein, J.L.3    Brown, M.S.4
  • 19
    • 0029878960 scopus 로고    scopus 로고
    • Regulated cleavage of sterol regulatory element binding proteins (SREBPs) requires sequences on both sides of the endoplasmic reticulum membrane
    • Hua, X., Sakai, J., Brown, M.S., and Goldstein, J.L. (1996b). Regulated cleavage of sterol regulatory element binding proteins (SREBPs) requires sequences on both sides of the endoplasmic reticulum membrane. J. Biol. Chem. 271, 10379-10384.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10379-10384
    • Hua, X.1    Sakai, J.2    Brown, M.S.3    Goldstein, J.L.4
  • 20
    • 0030007427 scopus 로고    scopus 로고
    • ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
    • Kim, J.B., and Spiegelman, B.M. (1996). ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev. 10, 1096-1107.
    • (1996) Genes Dev. , vol.10 , pp. 1096-1107
    • Kim, J.B.1    Spiegelman, B.M.2
  • 21
    • 0023613953 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel, T.A., Roberts, J.D., and Zakour, R.A. (1987). Rapid and efficient site-specific mutagenesis without phenotypic selection. Meth. Enzymol. 154, 367-382.
    • (1987) Meth. Enzymol. , vol.154 , pp. 367-382
    • Kunkel, T.A.1    Roberts, J.D.2    Zakour, R.A.3
  • 22
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte, J., and Doolittle, R.F. (1982). A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105-132.
    • (1982) J. Mol. Biol. , vol.157 , pp. 105-132
    • Kyte, J.1    Doolittle, R.F.2
  • 23
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 24
    • 0018214846 scopus 로고
    • Mammalian cell mutant requiring cholesterol and unsaturated fatty acid for growth
    • Limanek, J.S., Chin, J., and Chang, T.Y. (1978). Mammalian cell mutant requiring cholesterol and unsaturated fatty acid for growth. Proc. Natl. Acad. Sci. USA 75, 5452-5456.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 5452-5456
    • Limanek, J.S.1    Chin, J.2    Chang, T.Y.3
  • 25
    • 0030020577 scopus 로고    scopus 로고
    • Sterol regulation of acetyl CoA carboxylase: A mechanism for coordinate control of cellular lipid
    • Lopez, J.M., Bennett, M.K., Sanchez, H.B., Rosenfeld, J.M., and Osborne, T.F. (1996). Sterol regulation of acetyl CoA carboxylase: a mechanism for coordinate control of cellular lipid. Proc. Natl. Acad. Sci. USA 93, 1049-1053.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1049-1053
    • Lopez, J.M.1    Bennett, M.K.2    Sanchez, H.B.3    Rosenfeld, J.M.4    Osborne, T.F.5
  • 26
    • 12644314084 scopus 로고    scopus 로고
    • Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter
    • Magana, M.M., and Osborne, T.F. (1996). Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter. J. Biol. Chem. 271, 32689-32694.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32689-32694
    • Magana, M.M.1    Osborne, T.F.2
  • 27
    • 0029873473 scopus 로고    scopus 로고
    • Translational regulation of a leishmania HEXXH metalloprotease (gp63)
    • McGwire, B.S., and Chang, K.-P. (1996). Translational regulation of a leishmania HEXXH metalloprotease (gp63). J. Biol. Chem. 271, 7903-7909.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7903-7909
    • McGwire, B.S.1    Chang, K.-P.2
  • 28
    • 0024971244 scopus 로고
    • Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells
    • Metherall, J.E., Goldstein, J.L., Luskey, K.L., and Brown, M.S. (1989). Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells. J. Biol. Chem. 264, 15634-15641.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15634-15641
    • Metherall, J.E.1    Goldstein, J.L.2    Luskey, K.L.3    Brown, M.S.4
  • 30
    • 0029036451 scopus 로고
    • Evolutionary families of metallopeptidases
    • Rawlings, N.D., and Barrett, A.J. (1995). Evolutionary families of metallopeptidases. Meth. Enzymol. 248, 183-228.
    • (1995) Meth. Enzymol. , vol.248 , pp. 183-228
    • Rawlings, N.D.1    Barrett, A.J.2
  • 31
    • 0030604717 scopus 로고    scopus 로고
    • Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment
    • Sakai, J., Duncan, E.A., Rawson, R.B., Hua, X., Brown, M.S., and Goldstein, J.L. (1996). Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment. Cell 85, 1037-1046.
    • (1996) Cell , vol.85 , pp. 1037-1046
    • Sakai, J.1    Duncan, E.A.2    Rawson, R.B.3    Hua, X.4    Brown, M.S.5    Goldstein, J.L.6
  • 32
    • 0030854859 scopus 로고    scopus 로고
    • Identification of complexes between the COOH-terminal domains of sterol regulatory element binding proteins (SREBPs) and SREBP cleavage-activating protein (SCAP)
    • Sakai, J., Nohturfft, A., Cheng, D., Ho, Y.K., Brown, M.S., and Goldstein, J.L. (1997). Identification of complexes between the COOH-terminal domains of sterol regulatory element binding proteins (SREBPs) and SREBP cleavage-activating protein (SCAP). J. Biol. Chem. 272, 20213-20221.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20213-20221
    • Sakai, J.1    Nohturfft, A.2    Cheng, D.3    Ho, Y.K.4    Brown, M.S.5    Goldstein, J.L.6
  • 34
    • 0019162146 scopus 로고
    • Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing
    • Sanger, F., Coulson, A.R., Barrell, B.C., Smith, A.J.H., and Roe, B.A. (1980). Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J. Mol. Biol. 743, 161-178.
    • (1980) J. Mol. Biol. , vol.743 , pp. 161-178
    • Sanger, F.1    Coulson, A.R.2    Barrell, B.C.3    Smith, A.J.H.4    Roe, B.A.5
  • 35
    • 0029784838 scopus 로고    scopus 로고
    • Amyloid β-protein and the genetics of Alzheimer's disease
    • Selkoe, D.J. (1996). Amyloid β-protein and the genetics of Alzheimer's disease. J. Biol. Chem. 271, 18295-19298.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18295-19298
    • Selkoe, D.J.1
  • 37
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano, H., Horton, J.D., Hammer, R.E., Shimomura, I., Brown, M.S., and Goldstein, J.L. (1996). Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J. Clin. Invest. 98, 1575-1584.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 38
    • 0030054146 scopus 로고    scopus 로고
    • HLH106, a Drosophila transcription factor with similarity to the vertebrate sterol responsive element binding protein
    • Theopold, U., Ekengren, S., and Hultmark, D. (1996). HLH106, a Drosophila transcription factor with similarity to the vertebrate sterol responsive element binding protein. Proc. Natl. Acad. Sci. USA 93, 1195-1199.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1195-1199
    • Theopold, U.1    Ekengren, S.2    Hultmark, D.3
  • 39
    • 0027648820 scopus 로고
    • ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
    • Tontonoz, P., Kim, J.B., Graves, R.A., and Spiegelman, B.M. (1993). ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol. Cell. Biol. 13, 4753-4759.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4753-4759
    • Tontonoz, P.1    Kim, J.B.2    Graves, R.A.3    Spiegelman, B.M.4
  • 40
    • 0029930429 scopus 로고    scopus 로고
    • Identification of glutamate residues essential for catalytic activity and zinc coordination in aminopeptidase A
    • Vazeux, G., Wang, J., Corvol, P., and Llorens-Cortès, C. (1996). Identification of glutamate residues essential for catalytic activity and zinc coordination in aminopeptidase A. J. Biol. Chem. 271, 9069-9074.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9069-9074
    • Vazeux, G.1    Wang, J.2    Corvol, P.3    Llorens-Cortès, C.4
  • 41
    • 0028225462 scopus 로고
    • SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
    • Wang, X., Sato, R., Brown, M.S., Hua, X., and Goldstein, J.L. (1994). SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77, 53-62.
    • (1994) Cell , vol.77 , pp. 53-62
    • Wang, X.1    Sato, R.2    Brown, M.S.3    Hua, X.4    Goldstein, J.L.5
  • 42
    • 0029133344 scopus 로고
    • cDNA sequence and mRNAtissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment
    • Will, H. and Hinzmann, B. (1995). cDNA sequence and mRNAtissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment. Eur. J. Biochem. 231, 602-608.
    • (1995) Eur. J. Biochem. , vol.231 , pp. 602-608
    • Will, H.1    Hinzmann, B.2
  • 43
    • 0027992642 scopus 로고
    • ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1
    • Xu, D., Emoto, N., Giaid, A., Slaughter, C., Kaw, S., deWit, D., and Yanagisawa, M. (1994). ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell 78, 473-485.
    • (1994) Cell , vol.78 , pp. 473-485
    • Xu, D.1    Emoto, N.2    Giaid, A.3    Slaughter, C.4    Kaw, S.5    DeWit, D.6    Yanagisawa, M.7
  • 44
    • 0030853452 scopus 로고    scopus 로고
    • Specific increase in amyloid β-protein 42 secretion ratio by calpain inhibition
    • Yamazaki, T., Haass, C., Saido, T.C., Omura, S., and Ihara, Y. (1997). Specific increase in amyloid β-protein 42 secretion ratio by calpain inhibition. Biochemistry 36, 8377-8383.
    • (1997) Biochemistry , vol.36 , pp. 8377-8383
    • Yamazaki, T.1    Haass, C.2    Saido, T.C.3    Omura, S.4    Ihara, Y.5
  • 45
    • 0029025754 scopus 로고
    • Three different rearrangements in a single intron truncate SREBP-2 and produce sterol-resistant phenotype in three cell lines
    • Yang, J., Brown, M.S., Ho, Y.K., and Goldstein, J.L. (1995). Three different rearrangements in a single intron truncate SREBP-2 and produce sterol-resistant phenotype in three cell lines. J. Biol. Chem. 270, 12152-12161.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12152-12161
    • Yang, J.1    Brown, M.S.2    Ho, Y.K.3    Goldstein, J.L.4
  • 46
    • 0028133279 scopus 로고
    • Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2
    • Yang, J., Sato, R., Goldstein, J.L., and Brown, M.S. (1994). Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2. Genes Dev. 8, 1910-1919.
    • (1994) Genes Dev. , vol.8 , pp. 1910-1919
    • Yang, J.1    Sato, R.2    Goldstein, J.L.3    Brown, M.S.4
  • 47
    • 0027490174 scopus 로고
    • SREBP-1, a basic helix-loop-helix leucine zipper protein that controls transcription of the LDL receptor gene
    • Yokoyama, C., Wang, X., Briggs, M.R., Admon, A., Wu, J., Hua, X., Goldstein, J.L., and Brown, M.S. (1993). SREBP-1, a basic helix-loop-helix leucine zipper protein that controls transcription of the LDL receptor gene. Cell 75, 187-197.
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8


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