The effect of a secreted form of β-amyloid-precursor protein on intracellular Ca2+ increase in rat cultured hippocampal neurones

British Journal of Pharmacology

Volumn 123, Issue 8, 1998, Pages 1483-1489

  Koizumi, Schuichi ^a,c   Ishiguro, Mariko ^b   Ohsawa, Ikuroh ^b   Morimoto, Takako ^b   Takamura, Chizuko ^b   Inoue, Kazuhide ^a   Kohsaka, Shinichi ^b  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

amyloid precursor protein (APP); Inositol 1,4,5 trisphosphate; Intracellular Ca2+ concentration

Indexed keywords

AMYLOID BETA PROTEIN; CALCIUM ION; GLUTAMIC ACID; INOSITOL 1,4,5 TRISPHOSPHATE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR SPACE; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CALCIUM; CELLS, CULTURED; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INOSITOL 1,4,5-TRISPHOSPHATE; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 0031944765     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701712     Document Type: Article

References (31)

1. BARGER, S.W., FISCUS, R.R., RUTH, P., HOFMANN, F. & MATTSON, M.P. (1995). Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor. J. Neurochem., 64, 2087-2096.
2. BERRIDGE, M.J. (1995). Capacitative calcium entry. Biochem. J., 312, 1-11.
3. 3H-phosphoinositides mediated by muscarinic receptors in the developing chick retina: inhibition of carbachol-induced responses by glutamate receptors. J. Neurochem., 64, 1064-1070.
4. CREGG, J.M., BARRINGER, K.J., HESSLER, A.Y.H. & MADDEN, K.R. (1985). Pichia pastoris as a host system for transformations. Mol. Cell. Biol., 5, 3376-4485.
5. DESPREAUX, C.W. & MANNING, R.F. (1993). The dacA gene of Bacillus stearothermophilus coding for D-alanine carboxypeptidase: cloning, structure and expression in Escherichia coli and Pichia pastoris. Gene, 131, 35-41.
6. + channels and suppression of neuronal activity by secreted β-amyloid-precursor protein. Nature, 379, 74-78.
7. GREENBERG, S.K., KOO, E.H., SELKO, D.J., QIU, W.Q. & KOSIK, K.S. (1994). Secreted β-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances t phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 91, 7104-7108.
8. HAMANOUE, M., TAKEMOTO, N., MATSUMOTO, T., NAKAMURA, K., NAKAJIMA, K. & KOHSAKA, S. (1996). Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro. J. Neurosci. Res., 43, 554-564.
9. INOUE, K., NAKAZAWA, K., FUJIMORI, K., WATANO, T. & TAKANAKA, A. (1992). Extracellular adenosine 5′-triphosphate-evoked glutamate release in cultured hippocampal neurons. Neurosci. Lett., 134, 215-218.
10. JIN, L.W., NINOMIYA, H., ROCH, J.M., SCHUBERT, D., MASLIAH, E., OTERO, D.A. & SAITOH, T. (1994). Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension. J. Neurosci., 14, 5461-5470.
11. 125I secreted APP751 on intact fibroblast cells. Neurobiol. Aging, 11, 306.
12. KANG, J., LEMAIRE, H.-G., UNTERBECK, A., SALBAUM, J.M., MASTERS, C.L., GRZESCHIK, K.-H., MULTHAUP, G., BEYREUTHER, K. & MÜLLER-HILL, B. (1987). The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature, 325, 733-736.
13. 2+-mobilization in rat phaeochromocytoma cells. Br. J. Pharmacol., 115, 1502-1508.
14. KOIZUMI, S., WATANO, T., NAKAZAWA, K. & INOUE, K. (1994). Potentiation by adenosine of ATP-evoked dopamine release via a pertussis toxin-sensitive mechanism in rat phaeochromocytoma PC12 cells. Br. J. Pharmacol., 112, 992-997.
15. KUNO, M. & GARDNER, P. (1987). Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes. Nature, 326, 301-304.
16. LOIRAND, G., PACAUD, P., BARON, A., MIRONNEAU, C. & MIRONNEAU, J. (1991). Calcium activated cation channels in rat portal-vein myocytes. Zeitschrift fur Kardiologie, 80, 59-63.
17. 2+-permeable channel. Nature, 355, 356-358.
18. MATTSON, M.P. (1994). Secreted forms of β-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons. J. Neurobiol., 25, 439-450.
19. 2+ homeostasis in Alzheimer's disease. Trends Neurosci., 16, 409-414.
20. MATTSON, M.P., CHENG, B., DAVIS, D., BRYANT, K., LIEVERBURG, I. & RYDEL, R.E. (1992). β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci., 12, 376-389.
21. MATTSON, M.P., CHUNG, B., CULWELL, A.R., ESCH, F.S., LIEBERBURG, I. & RYDEL, R.E. (1993b). Evidence for excitoprotective and intraneuronal calcium-regulating roles of secreted forms of the β-amyloid precursor protein. Neuron, 10, 243-254.
22. NINOMIYA, H., ROCH, J.M., SUNDSMO, M.P., OTERO, D.A. & SAITOH, T. (1993). Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth J. Cell Biol., 121, 879-886.
23. 2+ elevating to depressing. J. Neurosci., 15, 5065-5077.
24. OHSAWA, I., HIROSE, Y., ISHIGURO, M., IMAI, Y., ISHIURA, S. & KOHSAKA, S. (1995). Expression, purification, and neurotrophic activity of amyloid precursor protein-secreted forms produced by yeast. Biochem. Biophys. Res. Commun., 213, 52-58.
25. OHSAWA, I., TAKAMURA, C. & KOHSAKA, S. (1997). The amino-terminal region of amyloid precursor protein is responsible for neurite outgrowth in rat neocortical explant culture. Biochem. Biophys. Res. Commun., 236, 59-65.
26. PUTNEY, J.W., JR. (1990). Capacitative calcium entry revisited. Cell Calcium, 11, 611-624.
27. 2+ influx in the neural retina of chick embryo. J. Neurobiol., 32, 66-68.
28. SELKOE, D.J. (1993). Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurosci., 16, 403-409.
29. SMITH-SWINTOSKY, V.L., PETTIGREW, L.C., CRADDOCK, S.D., CULWELL, A.R., RYDEL, R.E. & MATTSON, M.P. (1993). Secreted forms of amyloid β-proteins precursor protein protect hippocampal neurons against ischemic injury in vitro. Soc. Neurosci. Abstr., 19, 1251.
30. 2+ responses to ATP via purinoceptors in the early embryonic chick retina. J. Physiol., 493, 855-863.
31. WEIDEMANN, A., KÖNIG, G., BUNKE, D., FISHER, P., SALBAUM, J.M., MASTERS, C.L. & BEYREUTHER, K. (1989). Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell, 57, 115-126.