Relative increase in Alzheimer's disease of soluble forms of cerebral Aβ amyloid protein precursor containing the kunitz protease inhibitory domain

Journal of Biological Chemistry

Volumn 273, Issue 9, 1998, Pages 5013-5019

  Moir, Robert D ^a,b   Lynch, Toni ^a,b   Bush, Ashley I ^c   Whyte, Scott ^a,b   Henry, Anna ^a,b   Portbury, Stuart ^a,b   Multhaup, Gerd ^d   Small, David H ^a,b   Tanzi, Rudolph E ^c   Beyreuther, Konrad ^d   Masters, Colin L ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; MESSENGER RNA; SERINE PROTEINASE INHIBITOR;

ALZHEIMER DISEASE; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN PURIFICATION;

ALTERNATIVE SPLICING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; APROTININ; BRAIN CHEMISTRY; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SUBCELLULAR FRACTIONS; TRYPSIN INHIBITORS;

EID: 0032570571     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.9.5013     Document Type: Article

References (87)

1. Glenner, G. G., and Wong, C. W. (1984) Biochem. Biophys. Res. Commun. 120, 885-890
2. Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L., and Beyreuther, K. (1985) Proc. Natl. Acad. Sci., U. S. A. 82, 4245-4249
3. Citron, M., Haass, C., and Selkoe, D. J. (1993) Neurobiol. Aging 14, 571-573
4. Kang, J., Lemaire, H., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K., Multhaup, G., Beyreuther, K., and Müller-Hill, B. (1987) Nature 325, 733-736
5. Goldgaber, D., Lerman, M. I., McBride, O. W., Saffiotti, U., and Gajdusek, D. C. (1987) Science 235, 877-880
6. Tanzi, R. E., Gusella, J. F., Watkins, P. C., Bruns, G. A. P., St George-Hyslop, P., van Keuren, M. L., Patterson, D., Pagan, S., Kurnit, D. M., and Neve, R. L. (1987) Science 235, 880-884
7. Kitaguchi, N., Takahashi, Y., Tokushima, Y., Shiojiri, S., and Ito, H. (1988) Nature 331, 530-532
8. Tanzi, R. E., McClatchey, A. I., Lamperti, E. D., Villa-Komaroff, L., Gusella, J. F., and Neve, R. L. (1988) Nature 331, 528-530
9. Ponte, P., Gonzalez-DeWhitt, P., Schilling, J., Miller, J., Hsu, D., Greenberg, B., Davis, K., Wallace, W., Lieberburg, I., Fuller, F., and Cordell, B. (1988) Nature 331, 525-527
10. Weidemann, A., König, G., Bunke, D., Fischer, P., Salbaum, J. M., Masters, C. L., and Beyreuther, K. (1989) Cell 57, 115-126
11. Oltersdorf, T., Fritz, L. C., Schenk, D. B., Lieberburg, I., Johnson-Wood, K. L., Beattie, E. C., Ward, P. J., Blacher, R. W., Dovey, H. F., and Sinha, S. (1989) Nature 341, 144-147
12. Small, D. H., Nurcombe, V., Reed, G., Clarris, H., Moir, R., Beyreuther, K., and Masters, C. L. (1994) J. Neurosci. 14, 2117-2127
13. Bush, A. I., Multhaup, G., Moir, R. D., Williamson, T. G., Small, D. H., Bumble, B., Pollwein, P., Beyreuther, K., and Masters, C. L. (1993) J. Biol. Chem. 268, 16109-16112
14. Bush, A. I., Pettingell, W. H., de Paradis, M., Tanzi, R. E., and Wasco, W. (1994) J. Biol. Chem. 269, 26618-26621
15. Hesse, L., Beher, D., Masters, C. L., and Multhaup, G. (1994) FEBS Lett. 349, 109-116
16. Esch, F. S., Keim, P. S., Beattie, E. C., Blacher, H. W., Culwell, A. R., Oltersdorf, T., McClure, D., and Ward, P. J. (1990) Science 248, 1122-1124
17. Sisodia, S. S., Koo, E. H., Beyreuther, K., Unterbeck, A., and Price, D. L. (1990) Science 248, 492-495
18. Estus, S., Golde, T. E., Kunishita, T., Blades, D., Lowery, D., Eisen, M., Usiak, M., Qu, X., Tabira, T., Greenberg, B. D., and Younkin, S. G. (1992) Science 255, 726-728
19. Golde, T. E., Estus, S., Younkin, L. H., Selkoe, D. J., and Younkin, S. G. (1992) Science 255, 728-730
20. Haass, C., Koo, E. H., Mellon, A., Hung, A. Y., and Selkoe, D. J. (1992) Nature 357, 500-503
21. Koo, E. H., and Squazzo, S. L. (1994) J. Biol. Chem. 269, 17386-17389
22. Kounnas, M. Z., Moir, R. D., Hebeck, G. W., Bush, A. I., Argraves, W. S., Tanzi, R. E., Hyman, B. T., and Strickland, D. K. (1995) Cell 82, 331-340
23. Knauer, M. F., Orlando, R. A., and Glabe, C. G. (1996) Brain Res. 740, 6-14
24. Van Nostrand, W. E., and Cunningham, D. D. (1987) J. Biol. Chem. 262, 8508-8514
25. Neve, R. L., Boyce, F. M., McPhie, D. L., Greenan, J., and Oster-Granite, M. L. (1996) Neurobiol. Aging 17, 191-203
26. Golde, T. E., Estus, S., Usiak, M., Younkin, L. H., and Younkin, S. G. (1990) Neuron 4, 253-267
27. Tanaka, S., Liu, L., Kimura, J., Shiojiri, S., Takahashi, Y., Kitaguchi, N., Nakamura, S., and Ueda, K. (1992) Mol. Brain Res. 15, 303-310
28. Tanaka, S., Nakamura, S., Kimura, L., and Ueda, K. (1993) Neurosci. Lett. 163, 19-21
29. Johnson, S. A., Pasinetti, G. M., May, P. C., Ponte, P. A., Cordell, B., and Finch, C. E. (1988) Exp. Neurol. 102, 264-268
30. Johnson, S. A., Rogers, J., and Finch, C. E. (1989) Neurobiol. Aging 10, 267-272
31. Spillantini, M. G., Hunt, S. P., Ulrich, J., and Goedert, M. (1989) Mol. Brain Res. 6, 143-150
32. Johnson, S. A., McNeill, T., Cordell, B., and Finch, C. E. (1990) Science 248, 854-857
33. Neve, R. L., Finch, E. A., and Dawes, L. R. (1988) Neuron 1, 669-677
34. Tanaka, S., Nakamura, S., Ueda, K., Kameyama, M., Shiojiri, S., Takahashi, Y., Kitaguchi, N., and Ito, H. (1988) Biochem. Biophys. Res. Commun. 157, 472-479
35. Tanaka, S., Shiojiri, S., Takahashi, Y., Kitaguchi, N., Ito, H., Kameyama, M., Kimura, J., Nakamura, S., and Ueda, K. (1989) Biochem. Biophys. Res. Commun. 165, 1406-1414
36. Johnson, S. A., Norgren, S., Ravid, R., Wasco, W., Winblad, B., Lannfelt, L., and Cowburn, R. F. (1996) Mol. Brain Res. 43, 85-95
37. Okada, A., Urakami, K., Takahashi, K., Ohno, K., Sato, K. and Endo, H. (1994) Dementia 5, 55-56
38. Bockenstein, E. M., McConlogue, L., Tan, H., Power, M., Masliah, E., and Mucke, L. (1995) J. Biol. Chem. 270, 28257-28267
39. Kitaguchi, N., Tokushima, Y., Oishi, K., Takahashi, Y., Shiojiri, S., Nakamura, S., Tanaka, S., Kodaira, R., and Ito, H. (1990) Biochem. Biophys. Res. Commun. 166, 1453-1459
40. Palmert, M. R., Usiak, M., Mayeux, R., Raskind, M., Tourtellotte, W. W., and Younkin, S. G. (1990) Neurology 40, 1028-1034
41. Zhan, S. S., Sandbrink, R., Beyreuther, K., and Schmitt, H. P. (1995) Clin. Neuropathol. 14, 142-149
42. Abe, K., St. George-Hyslop, P. H., Tanzi, R. E., and Kogure, K. (1991) Neurosci. Lett. 125, 172-174
43. Kalaria, K. N., Bhatti, S. U., Palatinsky, E. A., Pennington, D. H., Shelton, E. R., Chan, H. W., Perry, G., and Lust, W. D. (1993) Neuroreport 4, 211-214
44. Solá, C., García-Landon, F. J., Mengod, G., Probst, A., Frey, P., and Palacios, J. M. (1993) Mol. Brain Res. 17, 41-52
45. Willoughby, D. A., Johnson, S. A., Pasinetti, G. M., Tocco, G., Najm, I., Baudry, M., and Finch, C. E. (1992) Exp. Neurol. 118, 332-339
46. Morgan, P. M., Higgins, L. S., Cordell, B., and Moser, P. C. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5341-5345
47. Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette, P., Blackwell, C., Carr, T., Clemens, J., Donaldson, T., Gillespie, F., Guido, T., Hagopian, S., Johnson-Wood, K., Khan, K., Lee, M., Leibowitz, P., Lieberburg, I., Little, S., Masliah, E., McConlogue, L., Montoya-Zavala, M., Mucke, L., Paganini, L., Penniman, E., Power, M., Schenk, D., Seubert, P., Snyder, B., Soriano, F., Tan, H., Vitale, J., Wadsworth, S., Wolozin, B., and Zhao, J. (1995) Nature 373, 523-527
48. Ho, L., Fukuchi, K., and Younkin, S. G. (1996) J. Biol. Chem. 271, 30929-30934
49. Hilbich, C., Manning, U., Grand, C., Masters, C. L., and Beyreuther, K. (1993) J. Biol. Chem. 268, 26571-26577
50. Moir, R. D., Martins, R. N., Small, D. H., Bush, A. I., Milward, E. A., Multhaup, G., Beyreuther, K., and Masters, C. L. (1992) J. Neurochem. 59, 1490-1498
51. Bush, A. I., Whyte, S., Thomas, L. D., Williamson, T. G., Van Tiggelen, C. J., Currie, J., Small, D. H., Moir, R. D., Li, Q. X., Rumble, B., Mönning, U., Beyreuther, K., and Masters, C. L (1992) Ann. Neurol. 32, 57-65
52. Kitaguchi, N., Takahashi, Y., Oishi, K., Shiojiri, S., Tokushima, Y., Utsunomiya, T., and Ito, H. (1990) Biochim. Biophys. Acta 1038, 105-113
53. Hynes, T. R., Randal, M., Kennedy, L. A., Eigenbrot, C., and Kossiakoff, A. A. (1990) Biochemistry 29, 10018-10022
54. Van Nostrand, W. E., Farrow, J. S., Wagner, S. L., Bhasin, R., Goldgaber, D., Cotman, C. W., and Cunningham, D. D. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 10302-10306
55. Hyman, B. T., Tanzi, R. E., Marzloff, K., Harbour, R., and Schenk, D. (1992) J. Neuropathol. Exp. Neurol. 51, 76-83
56. Moya, K. L., Confaloni, A. M., and Allinquant, B. (1994) J. Neurochem. 63, 1971-1974
57. Hyman, B. T., Wenniger, J. J., and Tanzi, R. E. (1993) Mol. Brain Res. 18, 253-258
58. Tanzi, R. E., Wenniger, J. J., and Hyman, B. T. (1993) Mol. Brain Res. 18, 246-252
59. Johnson, S. A., Norgren, S., Annerén, G., Cowburn, R. F., and Lannfelt, L. (1996) Mol. Brain Res. 43, 77-84
60. Bahmanyar, S., Higgins, G. A., Goldgaber, D., Lewis, D. A., Morrison, J. H., Wilson, M. C., Shankar, S. K., and Gajdusek, D. C. (1987) Science 237, 77-80
61. Goedert, M. (1987) EMBO J. 6, 3627-3632
62. Higgins, G. A., Lewis, D. A., Bahmanyar, S., Goldgaber, D., Gajdusek, D. C., Young, W. G., Morrison, J. H., and Wilson, M. C. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 1297-1301
63. Lewis, D. A., Higgins, G. A., Young, W. G., Goldgaber, D., Gajdusek, D. C., Wilson, M. C., and Morrison, J. H. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 1691-1695
64. Cohen, M. L., Golde, T. E., Usiak, M. F., Younkin, L. H., and Younkin, S. G. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 1227-1231
65. Palmert, M. R., Golde, T. E., Cohen, M. L., Kovacs, D. M., Tanzi, R. E., Gusella, J. F., Nsiak, M. F., Younkin, L. H., and Younkin, S. G. (1988) Science 241, 1080-1084
66. Schmechel, D. E., Goldgaber, D., Burkhart, D. S., Gilbert, J. R., Gajdusek, D. C., and Roses, A. D. (1988) Alzheimer Dis. Assoc. Disord. 2, 96-111
67. Shivers, B. D., Hilbich, C., Multhaup, G., Salbaum, M., Beyreuther, K., and Seeburg, P. H. (1988) EMBO J. 7, 1365-1370
68. Siman, R., Card, J. P., Nelson, R. B., and Davis, L. G. (1989)Neuron 3, 275-285
69. Mita, S., Schon, E. A., and Herbert, J. (1989) Am. J. Pathol. 134, 1253-1261
70. Jacobsen, J. S., Blume, A. J., and Vitek, M. P. (1991) Neurobiol. Aging 12, 585-592
71. Card, J. P., Meade, R. P., and Davis, L. G. (1988) Neuron 1, 835-846
72. Tate-Ostroff, B., Majocha, R. E., and Marotta, C. A. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 745-749
73. Arai, H., Lee, V. M-Y., Otvos, L., Jr., Greenberg, B. D., Lowery, D. E., Sharma, S. K., Schmidt, M. L., and Trojanowski, J. Q. (1991) Proc. Natl. Acad. Sci. U. S. A. 87, 2249-2253
74. Nakamura, S., Suenaga, T., Akiguchi, I., Kimura, J., Tokushima, Y., Kitaguchi, N., Takahashi, Y., and Shiojiri, S. (1992) Acta Neuropathol. (Berl). 84, 244-249
75. Koo, E. H., Sisodia, S. S., Cork, L. C., Unterbeck, A., Bayney, R. M., and Price, D. L. (1990) Neuron. 2, 97-104
76. Oyama, F., Shimada, H., Oyama, R., Titani, K., and Ihara, Y. (1991) J. Neuropathol. Exp. Neurol. 50, 560-578
77. König, G., Salbaum, J. M., Wiestler, O., Lang, W., Schmitt, H. P., Masters, C. L., and Beyreuther, K. (1991) Mol. Brain Res. 9, 259-262
78. Ohyagi, Y., Takahashi, K., Satoh, Y., Makifuchi, T., and Tabira, T. (1992) J. Neural. Sci. 111, 33-38
79. König, G., Mönning, U., Czech, C., Prior, R., Banati, R., Schreiter-Gasser, U., Bauer, J., Masters, C. L., and Beyreuther, K. (1992) J. Biol. Chem. 267, 10804-10809
80. Oyama, F., Shimada, H., Oyama, R., Titani, K., and Ihara, Y. (1992) J. Neurochem. 59, 1117-1125
81. Johnston, J. A., Cowburn, R. F., Norgren, S., Wiehager, B., Venizelos, N., and Winblad, B. (1994) FEBS Lett. 354, 274-278
82. Higgins, G. A., Oyler, G. A., Neve, R. L., Chen, K. S., and Gage, F. H. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 3032-3036
83. Higgins, L. S., and Cordell, B. (1995) Rev. Neurosci. 6, 87-96
84. Higgins, L. S., Catalano, R., Quon, D., and Cordell, B. (1993) Ann. N. Y. Acad. Sci. 695, 224-227
85. Higgins, G. A., Rodems, J. M., Catalano, R., Quon, D., and Cordell, B. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4402-4406
86. Hsiao, K. P., Chapman, S., Nilsen, C., Eckman, Y., Harigaya, S., Younkin, F., Yang, G., and Cole, G. M. (1996) Science 274, 99-102
87. Kawarabayashi, T., Shoji, M., Sato, M., Sasaki, A., Ho, L., Eckman, C. B., Prada, C. M., Younkin, S. G., Kobayashi, T., Tanda, N., Matsubara, E., Iizuka, T., Harigaya, Y., Kasai, K., and Hirai, S. (1996) Neurobiol. Aging. 17, 215-222