메뉴 건너뛰기




Volumn 70, Issue 2, 1998, Pages 524-530

Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade

Author keywords

Alzheimer disease; Amyloid peptide; Mitogen activated protein kinase; Protein kinase C

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MUSCARINIC M1 RECEPTOR;

EID: 0031952526     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70020524.x     Document Type: Article
Times cited : (110)

References (43)
  • 1
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi D. R., Cuenda A., Cohen P., Dudley D. T., and Saltiel A. R. (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 2
    • 0029066704 scopus 로고
    • Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease
    • Arendt T., Holzer M., Großmann A., Zeldick D., and Bruckner M. K. (1995) Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease. Neuroscience 68, 5-18.
    • (1995) Neuroscience , vol.68 , pp. 5-18
    • Arendt, T.1    Holzer, M.2    Großmann, A.3    Zeldick, D.4    Bruckner, M.K.5
  • 3
    • 0028176153 scopus 로고
    • Role of the beta-amyloid precursor protein in Alzheimer's disease
    • Ashall F. and Goate A. M. (1994) Role of the beta-amyloid precursor protein in Alzheimer's disease. Trends Biochem. Sci. 19, 42-46.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 42-46
    • Ashall, F.1    Goate, A.M.2
  • 4
    • 0026448114 scopus 로고
    • Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor
    • Buxbaum J. D., Oishi M., Chen H. I., Pinkas-Kramarski R., Jaffe E. A., Gandy S. E., and Greengard P. (1992) Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor. Proc. Natl. Acad. Sci. USA 89, 10075-10078.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10075-10078
    • Buxbaum, J.D.1    Oishi, M.2    Chen, H.I.3    Pinkas-Kramarski, R.4    Jaffe, E.A.5    Gandy, S.E.6    Greengard, P.7
  • 5
    • 0027435535 scopus 로고
    • Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide
    • Buxbaum J. D., Koo E. H., and Greengard P. (1993) Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide. Proc. Natl. Acad. Sci. USA 90, 9195-9198.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9195-9198
    • Buxbaum, J.D.1    Koo, E.H.2    Greengard, P.3
  • 6
    • 0028207004 scopus 로고
    • Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner
    • Buxbaum J. D., Ruefli A. A., Parker C. A., Cypess A. M., and Greengard P. (1994) Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner. Proc. Natl. Acad. Sci. USA 91, 4489-4493.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4489-4493
    • Buxbaum, J.D.1    Ruefli, A.A.2    Parker, C.A.3    Cypess, A.M.4    Greengard, P.5
  • 8
    • 0029379605 scopus 로고
    • Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease
    • Checler F. (1995) Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease. J. Neurochem. 65, 1431-1444.
    • (1995) J. Neurochem. , vol.65 , pp. 1431-1444
    • Checler, F.1
  • 9
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb M. H. and Goldsmith E. J. (1995) How MAP kinases are regulated. J. Biol. Chem. 270, 14843-14846.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 10
    • 0029328289 scopus 로고
    • Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein
    • da Cruz e Silva E. F., da Cruz e Silva O. A. B., Zaia C. T. B. V., and Greengard P. (1995) Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein. Mol. Med. 1, 535-541.
    • (1995) Mol. Med. , vol.1 , pp. 535-541
    • Da Cruz E Silva, E.F.1    Da Cruz E Silva, O.A.B.2    Zaia, C.T.B.V.3    Greengard, P.4
  • 12
    • 0029661438 scopus 로고    scopus 로고
    • Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin and calcineurin
    • Desdouits F., Buxbaum J. D., Desdouits-Magnen J., Nairn A. C., and Greengard P. (1996) Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin and calcineurin. J. Biol. Chem. 271, 24670-24674.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24670-24674
    • Desdouits, F.1    Buxbaum, J.D.2    Desdouits-Magnen, J.3    Nairn, A.C.4    Greengard, P.5
  • 15
    • 0028980783 scopus 로고
    • Intracellular production of βA4 amyloid of Alzheimer's disease: Modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein
    • Fuller S. J., Storey E., Li Q.-X., Smith A. I., Beyreuther K., and Masters C. L. (1995) Intracellular production of βA4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein. Biochemistry 34, 8091-8098.
    • (1995) Biochemistry , vol.34 , pp. 8091-8098
    • Fuller, S.J.1    Storey, E.2    Li, Q.-X.3    Smith, A.I.4    Beyreuther, K.5    Masters, C.L.6
  • 16
    • 0027332657 scopus 로고
    • Inhibition of β-amyloid production by activation of protein kinase C
    • Gabuzda D., Busciglio J., and Yankner B. A. (1993) Inhibition of β-amyloid production by activation of protein kinase C. J. Neurochem. 61, 2326-2329.
    • (1993) J. Neurochem. , vol.61 , pp. 2326-2329
    • Gabuzda, D.1    Busciglio, J.2    Yankner, B.A.3
  • 17
    • 2642679070 scopus 로고
    • Processing of Alzheimer Aβ amyloid precursor protein: Cell biology, regulation and role in Alzheimer's disease
    • Masters C. L., Beyreuther K., Trillet M., and Christen Y., eds, Springer-Verlag, Berlin/Heidelberg
    • Gandy S. E. and Greengard P. (1994) Processing of Alzheimer Aβ amyloid precursor protein: cell biology, regulation and role in Alzheimer's disease, in Amyloid Precursor Protein in Development, Aging and Alzheimer's Disease (Masters C. L., Beyreuther K., Trillet M., and Christen Y., eds), pp. 100-120. Springer-Verlag, Berlin/Heidelberg.
    • (1994) Amyloid Precursor Protein in Development, Aging and Alzheimer's Disease , pp. 100-120
    • Gandy, S.E.1    Greengard, P.2
  • 19
    • 0028057224 scopus 로고
    • Selective ectodomain phosphorylation and regulated cleavage of beta-amyloid precursor protein
    • Hung A. Y. and Selkoe D. J. (1994) Selective ectodomain phosphorylation and regulated cleavage of beta-amyloid precursor protein. EMBO J. 13, 534-542.
    • (1994) EMBO J. , vol.13 , pp. 534-542
    • Hung, A.Y.1    Selkoe, D.J.2
  • 22
    • 0029147583 scopus 로고
    • Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors
    • Lee R. K., Wurtman R. J., Cox A. J., and Nitsch R. M. (1995) Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proc. Natl. Acad. Sci. USA 92, 8083-8087.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8083-8087
    • Lee, R.K.1    Wurtman, R.J.2    Cox, A.J.3    Nitsch, R.M.4
  • 23
    • 0027367765 scopus 로고
    • Beta-amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease
    • Mattson M. P., Barger S. W., Cheng B., Lieberburg I., Smith-Swintosky V. L., and Rydel R. E. (1993) Beta-amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease. Trends Neurosci. 16, 409-414.
    • (1993) Trends Neurosci. , vol.16 , pp. 409-414
    • Mattson, M.P.1    Barger, S.W.2    Cheng, B.3    Lieberburg, I.4    Smith-Swintosky, V.L.5    Rydel, R.E.6
  • 24
    • 0030064136 scopus 로고    scopus 로고
    • Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein
    • McConlongue L., Castellano F., deWit C., Schenk D., and Maltese W. A. (1996) Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein. J. Biol. Chem. 271, 1343-1348.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1343-1348
    • McConlongue, L.1    Castellano, F.2    DeWit, C.3    Schenk, D.4    Maltese, W.A.5
  • 25
    • 0026663993 scopus 로고
    • The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neunte outgrowth
    • Milward E. A., Papadopoulos R., Fuller S. J., Moir R. D., Small D., Beyreuther K., and Masters C. L. (1992) The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neunte outgrowth. Neuron 9, 129-137.
    • (1992) Neuron , vol.9 , pp. 129-137
    • Milward, E.A.1    Papadopoulos, R.2    Fuller, S.J.3    Moir, R.D.4    Small, D.5    Beyreuther, K.6    Masters, C.L.7
  • 26
    • 0026476297 scopus 로고
    • Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
    • Nitsch R. M., Slack B. E., Wurtman R. J., and Growdon J. H. (1992) Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258, 304-307.
    • (1992) Science , vol.258 , pp. 304-307
    • Nitsch, R.M.1    Slack, B.E.2    Wurtman, R.J.3    Growdon, J.H.4
  • 27
    • 0029034774 scopus 로고
    • Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
    • Pang L., Sawada T., Decker S. J., and Saltiel A. R. (1995) Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J. Biol. Chem. 270, 13585-13588.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13585-13588
    • Pang, L.1    Sawada, T.2    Decker, S.J.3    Saltiel, A.R.4
  • 28
    • 0027978340 scopus 로고
    • Expression of protein phosphatase (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals
    • Pei J.-J., Sersen E., Iqbal K., and Grundke-Iqbal I. (1994) Expression of protein phosphatase (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals. Brain Res. 655, 70-76.
    • (1994) Brain Res. , vol.655 , pp. 70-76
    • Pei, J.-J.1    Sersen, E.2    Iqbal, K.3    Grundke-Iqbal, I.4
  • 29
    • 0029989591 scopus 로고    scopus 로고
    • Enhanced release of amyloid β-protein from codon 670/671 "Swedish" mutant β-amyloid precursor protein occurs in both secretory and endocytic pathways
    • Perez R. G., Squazzo S. L., and Koo E. H. (1996) Enhanced release of amyloid β-protein from codon 670/671 "Swedish" mutant β-amyloid precursor protein occurs in both secretory and endocytic pathways. J. Biol. Chem. 271, 9100-9107.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9100-9107
    • Perez, R.G.1    Squazzo, S.L.2    Koo, E.H.3
  • 30
    • 0026539617 scopus 로고
    • Growth factor-like effects mediated by muscarinic receptors in PC12M1 cells
    • Pinkas-Kramarski R., Stein R., Lindenboim L., and Sokolovsky M. (1992) Growth factor-like effects mediated by muscarinic receptors in PC12M1 cells. J. Neurochem. 59, 2158-2166.
    • (1992) J. Neurochem. , vol.59 , pp. 2158-2166
    • Pinkas-Kramarski, R.1    Stein, R.2    Lindenboim, L.3    Sokolovsky, M.4
  • 31
    • 0024466345 scopus 로고
    • Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures
    • Refolo L. M., Salton S. R., Anderson J. P., Mehta P., and Robakis N. K. (1989) Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures. Biochem. Biophys. Res. Commun. 164, 664-670.
    • (1989) Biochem. Biophys. Res. Commun. , vol.164 , pp. 664-670
    • Refolo, L.M.1    Salton, S.R.2    Anderson, J.P.3    Mehta, P.4    Robakis, N.K.5
  • 32
    • 0027367764 scopus 로고
    • Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease
    • Selkoe D. J. (1993) Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurosci. 16, 403-409.
    • (1993) Trends Neurosci. , vol.16 , pp. 403-409
    • Selkoe, D.J.1
  • 33
    • 0028170818 scopus 로고
    • Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease
    • Selkoe D. J. (1994) Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10, 373-403.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 373-403
    • Selkoe, D.J.1
  • 37
    • 0028985799 scopus 로고
    • Role of the beta-amyloid protein in Alzheimer's disease
    • Sisodia S. S. and Price D. L. (1995) Role of the beta-amyloid protein in Alzheimer's disease. FASEB J. 9, 366-370.
    • (1995) FASEB J. , vol.9 , pp. 366-370
    • Sisodia, S.S.1    Price, D.L.2
  • 38
    • 0028935040 scopus 로고
    • Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor
    • Slack B. E., Breu J., Petryniak M. A., Srivastava K., and Wurtman R. J. (1995) Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor. J. Biol. Chem. 270, 8337-8344.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8337-8344
    • Slack, B.E.1    Breu, J.2    Petryniak, M.A.3    Srivastava, K.4    Wurtman, R.J.5
  • 39
    • 0026750650 scopus 로고
    • Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C
    • Suzuki T., Nairn A. C., Gandy S. E., and Greengard P. (1992) Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C. Neuroscience 48, 755-761.
    • (1992) Neuroscience , vol.48 , pp. 755-761
    • Suzuki, T.1    Nairn, A.C.2    Gandy, S.E.3    Greengard, P.4
  • 40
    • 0030703718 scopus 로고    scopus 로고
    • Inducible expression of a mutant form of MEK1 in Swiss 3T3 cells
    • Syu L.-J., Guan K.-L., and Saltiel A. R. (1997) Inducible expression of a mutant form of MEK1 in Swiss 3T3 cells. J. Cell. Biochem. 67, 1-11.
    • (1997) J. Cell. Biochem. , vol.67 , pp. 1-11
    • Syu, L.-J.1    Guan, K.-L.2    Saltiel, A.R.3
  • 41
    • 0026534571 scopus 로고
    • Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinase
    • Thomas S. M., DeMarco M., D'Arcangelo G., Halegoua S., and Brugge J. S. (1992) Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinase. Cell 68, 1031-1040.
    • (1992) Cell , vol.68 , pp. 1031-1040
    • Thomas, S.M.1    DeMarco, M.2    D'Arcangelo, G.3    Halegoua, S.4    Brugge, J.S.5
  • 42
    • 0028926941 scopus 로고
    • Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells
    • Wolf B. A., Wertkin A. M., Jolly Y. C., Yasuda R. P., Wolfe B. B., Konrad R. J., Manning D., Ravi S., Williamson J. R., and Lee V. M.-Y. (1995) Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells. J. Biol. Chem. 270, 4916-4922.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4916-4922
    • Wolf, B.A.1    Wertkin, A.M.2    Jolly, Y.C.3    Yasuda, R.P.4    Wolfe, B.B.5    Konrad, R.J.6    Manning, D.7    Ravi, S.8    Williamson, J.R.9    Lee, V.M.-Y.10
  • 43
    • 0028859466 scopus 로고
    • Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein
    • Xu H., Greengard P., and Gandy S. (1995) Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein. J. Biol. Chem. 270, 23243-23245.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23243-23245
    • Xu, H.1    Greengard, P.2    Gandy, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.