Amyloid precursor protein truncated at any of the γ-secretase sites is not cleaved to β-amyloid

Journal of Neuroscience Research

Volumn 46, Issue 3, 1996, Pages 283-293

  Paganetti, Paolo A ^a   Lis, Maddalena ^a   Klafki, Hans Werner ^b   Staufenbiel, Matthias ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b Preclinical Research   (Switzerland)

Author keywords

Alzheimer's disease; neurodegeneration; protein processing; secretase; secretion

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ARTICLE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SECRETION;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; CELL LINE; CULTURE MEDIA; ENDOPEPTIDASES; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0029910609     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19961101)46:3<283::AID-JNR1>3.0.CO;2-G     Document Type: Article

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