Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease

Journal of Biological Chemistry

Volumn 271, Issue 34, 1996, Pages 20631-20635

  Roher, Alex E ^a   Chaney, Michael O ^b   Kuo, Yu Min ^a   Webster, Scott D ^a   Stine, W Blaine ^c   Haverkamp, Lanny J ^d   Woods, Amina S ^e   Cotter, Robert J ^e   Tuohy, James M ^a   Krafft, Grant A ^f   Bonnell, Barry S ^g   Emmerling, Mark R ^h  

^a SUN HEALTH RESEARCH INSTITUTE   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c ABBOTT LABORATORIES   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f NORTHWESTERN UNIVERSITY   (United States)

^g ARIZONA STATE UNIVERSITY   (United States)

^h PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID A PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); NEUROTOXIN; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMYLOID NEUROPATHY; ARTICLE; CHEMICAL COMPOSITION; CLINICAL ARTICLE; DIMERIZATION; ELECTRON MICROSCOPY; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; ANIMAL; ATOMIC FORCE MICROSCOPY; BLOOD VESSEL; BRAIN LEVEL; CELL CULTURE; CHEMISTRY; ISOLATION AND PURIFICATION; PATHOLOGY; RAT; ULTRASTRUCTURE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOOD VESSELS; BRAIN CHEMISTRY; CELLS, CULTURED; MICROSCOPY, ATOMIC FORCE; NEUROTOXINS; PEPTIDE FRAGMENTS; RATS;

EID: 9444245809     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.34.20631     Document Type: Article

References (36)

1. Selkoe, D. J. (1996) J. Biol. Chem. 271, 18295-18298
2. Roher, A. E., Lowenaon, J. D., Clarke, S., Wolkow, C., Wang, R., Cotter, R. J., Reardon, I. M., Zürcher-Neely, H. A., Heinrikson, R. L., Ball, M. J. and Greenberg, B. D. (1993) J. Biol. Chem. 268, 3072-3083
3. Seubert, P., Vigo-Pelfrey, C., Each, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schlossmacher, M., Whaley, J., Swindlehurst, C., McCormack, R., Wolfert, R., Selkoe, D., Lieberburg, I., and Schenk, D. (1992) Nature 359, 325-327
4. Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B. L., Lieberburg, I., Koo, E. H., Schenk, D., Teplow, D. B. and Selkoe, D. J. (1992) Nature 359, 322-325
5. Shoji, M., Golde, T. E., Ghiso, J., Cheung, T. T., Estus, S., Shatter, L. M., Cai, X. D., McKay, D. M., Tintner, R., Frangione, B., and Younkin, S. G. (1992) Science 258, 126-129
6. Tabaton, M., Nunzi, M. G., Xue, R., Usiak, M., Autilio-Gambetti, L., and Gambetti, P. (1994) Biochem. Biophys. Res. Commun. 200, 1598-1603
7. Wisniewski, T., Ghiso, J., and Frangione, B. (1994) Neurobiol. Aging 15, 143-152
8. Tamaoka, A., Kondo, T., Odaka, A., Sahara, N., Sawamura, N., Ozawa, K., Suzuki, N., Shoji, S., and Mori, H. (1994) Biochem. Biophys. Res. Commun. 205, 834-842
9. Harigaya, Y., Shoji, M., Kawarabayashi, T., Kanai, M., Nakamura, T., Iizuka, T., Igeta, Y., Saido, T. C., Sahara, N., Mori, H., and Hirai, S. (1995) Biochem. Biophys. Res. Commun, 211, 1015-1022
10. Shinkai, Y., Yoshimura, M., Yuji, I., Odaka, A., Suzuki, N., Yanagisawa, K., and Ihara, Y. (1995) Ann. Neurol. 38, 421-428
11. Podlisny, M. B., Ostaszewski, B. L., Squazzo, S. L., Koo, E. H., Hydell, R. E., Teplow, D. B., and Selkoe, D. J. (1995) J. Biol. Chem. 270, 9564-9570
12. Teller, J. K., Russo, C., Debusk, L. M., Angelini, G., Zaccheo, D., Dagna-Bricarelli, F., Scartezzini, P., Bertocini, S., Mann, D. M. A., Tabaton, M., and Gambetti, P. (1996) Nat. Med. 2, 93-95
13. Kuo, Y.-M., Emmerling, M. R., Vigo-Pelfrey, C., Kasunic, T. C., Kirkpatrick, J. B., Murdoch, G. H., Ball, M. J., and Roher, A. E. (1996) J. Biol. Chem. 271, 4077-4081
14. Roher, A. E., Lowenson, J. D., Clarke, S., Woods, A. S., Cotter, R. J., Gowing, E., and Ball, M. J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10836-10840
15. Roher, A. E., Palmer, K. C., Yurewicz, E. C., Ball, M. J., and Greenberg, B. D. (1993) J. Neurochem. 81, 1916-1926
16. Mirra, S. S., Hart, M. N., and Terry, R. D. (1993) Arch. Pathol. Lab. Med. 117, 132-144
17. Stine, W. B., Snyder, S. W., Ladror, U. S., Wade, W. S., Miller, M. F., Perun, T. J., Holzman, T. F., and Krafft, G. A. (1996) J. Protein Chem. 15, 193-203
18. Bonnell, B., and Chandler, D. (1990) J. Struct. Biol. 105, 123-132
19. Chilian, D., and Baker, T. J. (1986) J. Neurosci. 6, 2163-2178
20. Giulian, D., Haverkamp, L. J., Li, J., Karshin, W. L., Yu, J., Tom, D., Li, X. and Kirkpatrick, J. B. (1995) Neurochem. Int. 27, 119-137
21. Davis, T. L., and Wiley, R. G. (1989) Brain Res. 504, 216-222
22. Mattson, M. P., Cheng, B., Davis, D., Bryant, K., Lieberburg, I., and Rydell, R. E. (1992) J. Neurosci. 12, 376-389
23. Copani, A., Koh, J.-Y., and Cotman, C. W. (1991) Neuroreport 2, 763-765
24. Giulian, D. (1992) in Current Neurology (Appel, S. H., ed) Vol. 12, pp. 23-54, Mosby-Year Book, Inc., St. Louis, MO
25. Banati, R. B., Gehrmann, J., Schubert, P., and Kreutzberg, G. W. (1993) Glia 7, 111-118
26. Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., De Teresa, R., Hill, R., Hansen, L. A., and Katzman, R. (1991) Ann. Neurol. 30, 572-580
27. Mann, D. M., Marcyniuk, B., Yates, P. O., Neary, D., and Snowden, J. S. (1988) Neuropathol. Appl. Neurobiol. 14, 177-195
28. Davis-Salinas, J., and Van Nostrand, W. E. (1995) J. Biol. Chem. 270, 20887-20890
29. Hsiao, K. K., Borchelt, D. R., Olson, K., Johannsdottir, R., Kitt, C., Yunis, W., Xu, S., Eckman, C., Younkin, S., Price, D., Iadecola, C., Clark, H. B., and Carlson, G. (1995) Neuron 15, 1203-1218
30. Vigo-Pelfrey, C., Lee, D., Keim, P., Lieberburg, I., and Schenk, D. B. (1993) J. Neurochem. 61, 1965-1968
31. Miyakawa, T., Katsuragi, S., Yamashita, K., and Ohuchi, K. (1992) Acta Neuropathol. 83, 340-346
32. Vinores, S. A., and Herman, M. M. (1993) J. Neuroimmunol. 43, 169-176
33. Martin, D. L. (1992) Glia 5, 81-94
34. Giulian, D., Chen, J., Ingeman, J. E., George, J., and Noponen, M. (1989) J. Neurosci. 9, 4416-4429
35. Frautschy, S. A., Cole, G. M., and Baird, A. (1992) Am. J. Pathol. 140, 1389-1399
36. Rogers, J., Webster, S., Lue, L.-F., Brachova, L., Civin, W. H., Emmerling, M., Shivers, B., Walker, D., and McGeer, P. (1996) Neurobiol. Aging 17, in press