-
1
-
-
0023838532
-
1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
-
1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 52, 487-501.
-
(1988)
Cell
, vol.52
, pp. 487-501
-
-
Abraham, C.A.1
Selkoe, D.J.2
Potter, H.3
-
2
-
-
0028943243
-
Notch signaling
-
Artavanis-Tsakonas, S., Matsuno, K., and Fortini, M.E. (1995). Notch signaling. Science 265, 225-232.
-
(1995)
Science
, vol.265
, pp. 225-232
-
-
Artavanis-Tsakonas, S.1
Matsuno, K.2
Fortini, M.E.3
-
3
-
-
0028176153
-
Role of the beta-amyloid precursor protein in Alzheimer's disease
-
Ashall, F., and Goate, A.M. (1994). Role of the beta-amyloid precursor protein in Alzheimer's disease. Trends Biochem. Sci. 19, 42-46.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 42-46
-
-
Ashall, F.1
Goate, A.M.2
-
4
-
-
0004265596
-
-
New York: Greene Publishing Associates and Wiley-lnterscience
-
Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., and Smith, J.A. (1989). Current Protocols in Molecular Biology. (New York: Greene Publishing Associates and Wiley-lnterscience).
-
(1989)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
-
5
-
-
0023932891
-
The intracellulardistribution of the transformation-associated protein p53 in adenovirus-transformed rodent cells
-
Blair Zajdel, M.E., and Blair, G.D. (1988). The intracellulardistribution of the transformation-associated protein p53 in adenovirus-transformed rodent cells. Oncogene 2, 579-584.
-
(1988)
Oncogene
, vol.2
, pp. 579-584
-
-
Blair Zajdel, M.E.1
Blair, G.D.2
-
6
-
-
0019849638
-
Kinetochore structure, duplication, and distribution in mammalian cells: Analysis by human autoantibodies from scleroderma patients
-
Brenner, S., Pepper, D., Berns, M.W., Tan, E., and Brinkley, B.R. (1981). Kinetochore structure, duplication, and distribution in mammalian cells: analysis by human autoantibodies from scleroderma patients. J. Cell Biol. 91, 95-102.
-
(1981)
J. Cell Biol.
, vol.91
, pp. 95-102
-
-
Brenner, S.1
Pepper, D.2
Berns, M.W.3
Tan, E.4
Brinkley, B.R.5
-
7
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membranebound transcription factor
-
Brown, M.S., and Goldstein, J.L. (1997). The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membranebound transcription factor. Cell 89, 331-340.
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
8
-
-
0029417023
-
Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
-
Busciglio, J., and Yankner, B.A. (1995). Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature 375, 776-779.
-
(1995)
Nature
, vol.375
, pp. 776-779
-
-
Busciglio, J.1
Yankner, B.A.2
-
9
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice
-
Citron, M., Westaway, D., Xia, W., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K., Lee, M., Seubert, P., Davis, A., et al. (1997). Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nature Medicine 3, 67-72.
-
(1997)
Nature Medicine
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
-
11
-
-
0028889206
-
Expression of the Alzheimer amyloidpromoting factor antichymotrypsin is induced in human astrocytes by IL-1
-
Das, S.,and Potter, H. (1995). Expression of the Alzheimer amyloidpromoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron 14, 447-456.
-
(1995)
Neuron
, vol.14
, pp. 447-456
-
-
Das, S.1
Potter, H.2
-
12
-
-
0030580281
-
Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells
-
Deng, G., Pike, C.J., and Cotman, C.W. (1996). Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells. FEBS Letters 397, 50-54.
-
(1996)
FEBS Letters
, vol.397
, pp. 50-54
-
-
Deng, G.1
Pike, C.J.2
Cotman, C.W.3
-
13
-
-
15444341611
-
Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins
-
De Strooper, B., Beullens, M., Contreras, B., Levesque, L., Craessaerts, K., Cordell, B., Moechars, D., Bollen, M., Fraser, P., St. George Hyslop, P., and Leuven, F. Van (1997). Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins. J. Biol. Chem. 272, 3590-3598.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3590-3598
-
-
De Strooper, B.1
Beullens, M.2
Contreras, B.3
Levesque, L.4
Craessaerts, K.5
Cordell, B.6
Moechars, D.7
Bollen, M.8
Fraser, P.9
St George Hyslop, P.10
Van Leuven, F.11
-
14
-
-
0030033587
-
Genetic clues to Alzheimer's disease
-
Dewji, N.N., and Singer, S.J. (1996). Genetic clues to Alzheimer's disease. Science 271, 159-160.
-
(1996)
Science
, vol.271
, pp. 159-160
-
-
Dewji, N.N.1
Singer, S.J.2
-
15
-
-
0030293854
-
Protein topology of presenilin 1
-
Doan, A., Thinakaran, G., Borchelt, D., Slunt, H.H., Ratovitsky, T., Podlisny, M., Selkoe, D.J., Seeger, M., Gandy, S.E., Price, D.L., and Sisodia, S.S. (1996). Protein topology of presenilin 1. Neuron 17, 1023-1030.
-
(1996)
Neuron
, vol.17
, pp. 1023-1030
-
-
Doan, A.1
Thinakaran, G.2
Borchelt, D.3
Slunt, H.H.4
Ratovitsky, T.5
Podlisny, M.6
Selkoe, D.J.7
Seeger, M.8
Gandy, S.E.9
Price, D.L.10
Sisodia, S.S.11
-
16
-
-
0028951801
-
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgeneic mice and promotes chromosomal instability
-
Donehower, L.A., Godley, L.A., Aldaz, C.M., Pyle, R., Shi, Y-P., Pinkel, D., Gray, J., Bradley, A., Medina, D., and Varmus, H.E. (1995). Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgeneic mice and promotes chromosomal instability. Genes Dev. 9, 882-895.
-
(1995)
Genes Dev.
, vol.9
, pp. 882-895
-
-
Donehower, L.A.1
Godley, L.A.2
Aldaz, C.M.3
Pyle, R.4
Shi, Y.-P.5
Pinkel, D.6
Gray, J.7
Bradley, A.8
Medina, D.9
Varmus, H.E.10
-
17
-
-
16044366039
-
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
-
Duff, K., Eckman, C., Zher, C., Yu, X., Prada, C.-M., Perez-Tur, J., Hutton, M., Buee, L, Harigaya, Y., Yager, D., etal. (1996). Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1. Nature 353, 710-713.
-
(1996)
Nature
, vol.353
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zher, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
-
18
-
-
10144234151
-
Identification and neuron specific expression of the S182/presenilin 1 protein in human and rodent brains
-
Elder, G.A., Tezapsidis, N., Carter, J., Shioi, J., Bouras, C., Li, H.-C., Johnston, J.M., Efthimiopoulos, S., Friedrich, V.L., Jr., and Robakis, N.K. (1996). Identification and neuron specific expression of the S182/presenilin 1 protein in human and rodent brains. J. Neurosci. 45, 308-320.
-
(1996)
J. Neurosci.
, vol.45
, pp. 308-320
-
-
Elder, G.A.1
Tezapsidis, N.2
Carter, J.3
Shioi, J.4
Bouras, C.5
Li, H.-C.6
Johnston, J.M.7
Efthimiopoulos, S.8
Friedrich Jr., V.L.9
Robakis, N.K.10
-
19
-
-
0029881977
-
Abnormal centrosome amplification in the absence of p53
-
Fukawawa, K., Choi, T., Kuriyama, R., Rulong, S., Vande Woude, G.F. (1996). Abnormal centrosome amplification in the absence of p53. Science 271, 1744-1747.
-
(1996)
Science
, vol.271
, pp. 1744-1747
-
-
Fukawawa, K.1
Choi, T.2
Kuriyama, R.3
Rulong, S.4
Vande Woude, G.F.5
-
20
-
-
0001360461
-
Brain interleukin-1 and S100 immunoreactivity elevated in Down's syndrome and Alzheimer's disease
-
Griffin, W.S.T., Stanley, L.C., Ling, C., White, L., MacLeod, V., Perrot, L.J., White III, C.L., and Araoz, C., (1989). Brain interleukin-1 and S100 immunoreactivity elevated in Down's syndrome and Alzheimer's disease. Proc. Natl. Acad. Sci. USA 86, 7611-7615.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7611-7615
-
-
Griffin, W.S.T.1
Stanley, L.C.2
Ling, C.3
White, L.4
MacLeod, V.5
Perrot, L.J.6
White III, C.L.7
Araoz, C.8
-
21
-
-
0029779589
-
Presenile because of presenilin: The presenilin genes and early onset Alzheimer's disease
-
Haass, C. (1996). Presenile because of presenilin: the presenilin genes and early onset Alzheimer's disease. Curr. Opin. Neurol. 9, 254-259.
-
(1996)
Curr. Opin. Neurol.
, vol.9
, pp. 254-259
-
-
Haass, C.1
-
22
-
-
0028990941
-
ApoE4-associated Alzheimer's disease risk is modified by α1-antichymotrypsin polymorphism
-
Kamboh, M.I., Sanghera, O.K., Ferrell, R.E., and DeKosky, ST. (1995). ApoE4-associated Alzheimer's disease risk is modified by α1-antichymotrypsin polymorphism. Nature Genet. 10, 486-488.
-
(1995)
Nature Genet.
, vol.10
, pp. 486-488
-
-
Kamboh, M.I.1
Sanghera, O.K.2
Ferrell, R.E.3
Dekosky, S.T.4
-
23
-
-
0026649165
-
Formation and activation of acyclin E-cdk2 complex during the G1 phase of the human cell cycle
-
Koff, A., Giordano, A., Desai, D., Yamashita, K., Harper, J.W., Elledge, S., Nishimoto, T., Morgan, D.O., Franza, B.R., and Roberts, J. (1992). Formation and activation of acyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science 257, 1689-1694.
-
(1992)
Science
, vol.257
, pp. 1689-1694
-
-
Koff, A.1
Giordano, A.2
Desai, D.3
Yamashita, K.4
Harper, J.W.5
Elledge, S.6
Nishimoto, T.7
Morgan, D.O.8
Franza, B.R.9
Roberts, J.10
-
24
-
-
0030003538
-
Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation bytheextracellular domain
-
Kopan, R., Schroeter, E.H., Weintraub, H., and Nye, J.S. (1996). Signal transduction by activated mNotch: importance of proteolytic processing and its regulation bytheextracellular domain. Proc. Natl. Acad. Sci. USA 93, 1683-1688.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1683-1688
-
-
Kopan, R.1
Schroeter, E.H.2
Weintraub, H.3
Nye, J.S.4
-
25
-
-
13344282063
-
Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
-
Kovacs, D.M., Fausett, H.J., Page, K.J., Kim, T.W., Moir, R.D., Merriam, D.E., Hollister, R.D., Hallmark, O.G., Mancini, R., Felsenstein, K.M., et al. (1996). Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nature Med. 2, 224-229.
-
(1996)
Nature Med.
, vol.2
, pp. 224-229
-
-
Kovacs, D.M.1
Fausett, H.J.2
Page, K.J.3
Kim, T.W.4
Moir, R.D.5
Merriam, D.E.6
Hollister, R.D.7
Hallmark, O.G.8
Mancini, R.9
Felsenstein, K.M.10
-
26
-
-
0029609021
-
Increased production of 4KDa amyloid beta peptide in serum-deprived human primary neuron cultures: Possible involvement of apoptosis
-
LeBlanc, A. (1995). Increased production of 4KDa amyloid beta peptide in serum-deprived human primary neuron cultures: possible involvement of apoptosis. J. Neurosci. 15, 7837-7846.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7837-7846
-
-
LeBlanc, A.1
-
27
-
-
0031004175
-
Genetic instability on colorectal cancers
-
Lengauer, G., Kinzler, K.W., and Vogelstein, B. (1997). Genetic instability on colorectal cancers. Nature 356, 623-630.
-
(1997)
Nature
, vol.356
, pp. 623-630
-
-
Lengauer, G.1
Kinzler, K.W.2
Vogelstein, B.3
-
28
-
-
0029116848
-
Facilitation of lin-72-mediated signaling by sel-12, a Caenorhabditis elegans S182Alzheimer's disease gene
-
Levitan, D., and Greenwald, I. (1995). Facilitation of lin-72-mediated signaling by sel-12, a Caenorhabditis elegans S182Alzheimer's disease gene. Nature 377, 351-354.
-
(1995)
Nature
, vol.377
, pp. 351-354
-
-
Levitan, D.1
Greenwald, I.2
-
29
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D.M., Oshima, J., Pettingell, W.H., Yu, C.-E., Jondro, P.D., Schmidt, S.D., Wang, K., et al. (1995a). Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269, 973-976.
-
(1995)
Science
, vol.269
, pp. 973-976
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.-E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
-
30
-
-
0029150716
-
A familial Alzheimer's disease locus on chromosome 1
-
Levy-Lahad, E., Wijsman, E.M., Nemens, E., Anderson, L., Goddard, K.A.B., Weber, J.L., Bird, T.D., and Schellenberg, G.D. (1995b). A familial Alzheimer's disease locus on chromosome 1. Science 269, 970-973.
-
(1995)
Science
, vol.269
, pp. 970-973
-
-
Levy-Lahad, E.1
Wijsman, E.M.2
Nemens, E.3
Anderson, L.4
Goddard, K.A.B.5
Weber, J.L.6
Bird, T.D.7
Schellenberg, G.D.8
-
31
-
-
0030293894
-
Mem brane topology of the C. elegans sel-12 presenilin
-
Li,X., and Greenwald, I. (1996). Mem brane topology of the C. elegans sel-12 presenilin. Neuron 17, 1015-1021
-
(1996)
Neuron
, vol.17
, pp. 1015-1021
-
-
Li, X.1
Greenwald, I.2
-
32
-
-
0029618686
-
Identification and expression analysis of a potential familial Alzheimer's diseasegene on chromosome 1 related to AD3
-
Li, J., Ma, J., and Potter, H. (1995). Identification and expression analysis of a potential familial Alzheimer's diseasegene on chromosome 1 related to AD3. Proc. Natl. Acad. Sci. USA 92, 12180-12184.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12180-12184
-
-
Li, J.1
Ma, J.2
Potter, H.3
-
33
-
-
0028173205
-
Amyloidassociated proteins 1,-antichymotrypsin and apolipoprotein e promote assembly of Alzheimer β-protein into filaments
-
Ma, J., Yee, A., Brewer, H.B., Das, S., and Potter, H. (1994). Amyloidassociated proteins (1,-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 372, 92-94.
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer, H.B.3
Das, S.4
Potter, H.5
-
34
-
-
0000448998
-
Alzheimer Aβ neurotoxicity: Promotion by antichymotrypsin, ApoE4; inhibition by Aβ-related peptides
-
Ma, J., Brewer, H.B., Jr., and Potter, H. (1996). Alzheimer Aβ neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by Aβ-related peptides. Neurobiol. Aging 17, 773-780.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 773-780
-
-
Ma, J.1
Brewer Jr., H.B.2
Potter, H.3
-
35
-
-
0029416825
-
High levels of amyloid- protein from S182 (Glu246) familial Alzheimer's cells
-
Martins, R.N., Turner, B.A., Carrol I, R.T., Sweeney, D., Kim, K.S., Wisniewski, H.M., Blass, J.P., Gibson, G.E., and Gandy, S. (1995). High levels of amyloid- protein from S182 (Glu246) familial Alzheimer's cells. NeuroReport 7, 217-220.
-
(1995)
NeuroReport
, vol.7
, pp. 217-220
-
-
Martins, R.N.1
Turner, B.A.2
Carrol, I.R.T.3
Sweeney, D.4
Kim, K.S.5
Wisniewski, H.M.6
Blass, J.P.7
Gibson, G.E.8
Gandy, S.9
-
36
-
-
0020521948
-
Autoimmune response directed against conserved determinants on nuclear envelope proteins in a patient with linear scleroderma
-
McKeon, F.D., Tuffanelli, D.L., Fukuyama, K., and Kirschner, M.W. (1983). Autoimmune response directed against conserved determinants on nuclear envelope proteins in a patient with linear scleroderma. Proc. Natl. Acad. Sci. USA SO, 4374-4378.
-
(1983)
Proc. Natl. Acad. Sci. USA
, pp. 4374-4378
-
-
McKeon, F.D.1
Tuffanelli, D.L.2
Fukuyama, K.3
Kirschner, M.W.4
-
37
-
-
0030575338
-
Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing
-
Mercken, M., Takahashi, H., Honda, T., Sato, K., Murayama, M., Nakazato, Y., Noguchi, K., Imahori, K., and Takashima, A. (1996). Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: evidence that Alzheimer mutations affect proteolytic processing. FEBS Lett. 359, 297-303.
-
(1996)
FEBS Lett.
, vol.359
, pp. 297-303
-
-
Mercken, M.1
Takahashi, H.2
Honda, T.3
Sato, K.4
Murayama, M.5
Nakazato, Y.6
Noguchi, K.7
Imahori, K.8
Takashima, A.9
-
38
-
-
0030462777
-
The mammalian centromere: Its molecular architecture
-
Mitchell, A.R. (1996). The mammalian centromere: its molecular architecture. Mutation Research 372, 153-62.
-
(1996)
Mutation Research
, vol.372
, pp. 153-162
-
-
Mitchell, A.R.1
-
39
-
-
0019725968
-
Distribution of kinetochore (centromere) antigen in mammalian cell nuclei
-
Moroi, Y., Hartman, A.L., Nakane, P.K., and Tan, E.M. (1981). Distribution of kinetochore (centromere) antigen in mammalian cell nuclei. J. Cell Biol. 90, 254-259.
-
(1981)
J. Cell Biol.
, vol.90
, pp. 254-259
-
-
Moroi, Y.1
Hartman, A.L.2
Nakane, P.K.3
Tan, E.M.4
-
40
-
-
0029984314
-
Immunohistochemical analysis of presenilin-1 expression in the mouse brain
-
Moussaoui, S., Czech, C., Pradier, L., Blanchard, V., Bonici, B., Gohin, M., Imperato, A., and Revah, F. (1996). Immunohistochemical analysis of presenilin-1 expression in the mouse brain. FEBS Lett. 353, 219-222.
-
(1996)
FEBS Lett.
, vol.353
, pp. 219-222
-
-
Moussaoui, S.1
Czech, C.2
Pradier, L.3
Blanchard, V.4
Bonici, B.5
Gohin, M.6
Imperato, A.7
Revah, F.8
-
41
-
-
0025801967
-
Review and hypothesis: Alzheimer disease and Down syndrome-chromosome 21 nondisjunction may underlie both disorders
-
Potter, H. (1991). Review and hypothesis: Alzheimer disease and Down syndrome-chromosome 21 nondisjunction may underlie both disorders. Am. J. Hum. Genet. 48, 1192-1200.
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 1192-1200
-
-
Potter, H.1
-
42
-
-
85046112443
-
Alzheimer's disease, Down's syndrome, and chromosome segregation
-
Potter, H., and Geller, L.N. (1996). Alzheimer's disease, Down's syndrome, and chromosome segregation. The Lancet 346, 66.
-
(1996)
The Lancet
, vol.346
, pp. 66
-
-
Potter, H.1
Geller, L.N.2
-
43
-
-
0001444987
-
Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation
-
Potter, H., Weir, L., and Leder, P. (1984). Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation. Proc. Natl. Acad. Sci. USA 81, 7161-7165.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 7161-7165
-
-
Potter, H.1
Weir, L.2
Leder, P.3
-
44
-
-
0001421726
-
Beyond β-protein: New steps in the pathogenic pathway to Alzheimer's disease
-
K. Iqbal, J.A. Mortimer, B. Winblad, and W.H. Wisniewski, eds. New York: John Wiley and Sons
-
Potter, H., Ma, J., Das, S., Geller, L.N., Benjamin, M., Kayyali, U.S. and Dressler, D. (1995). Beyond β-protein: new steps in the pathogenic pathway to Alzheimer's disease. In Research Advances in Alzheimer's Disease and Related Disorders, K. Iqbal, J.A. Mortimer, B. Winblad, and W.H. Wisniewski, eds. (New York: John Wiley and Sons, pp. 643-654).
-
(1995)
Research Advances in Alzheimer's Disease and Related Disorders
, pp. 643-654
-
-
Potter, H.1
Ma, J.2
Das, S.3
Geller, L.N.4
Benjamin, M.5
Kayyali, U.S.6
Dressler, D.7
-
45
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev, E.I., Sherrington, R., Rogaeva, E.A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Lin, G., Holman, K., Tsuda, T., et al. (1995). Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, G.8
Holman, K.9
Tsuda, T.10
-
46
-
-
0028026587
-
Apolipoprotein e associates with amyloid peptide of Alzheimer's disease to form novel monofibrils
-
Sanan, D.A., Weisgraber, K.H., Russell, S.J., Mahley, R.W., Huang, D., Saunders, A., Schmechel, D., Wisniewski, T., Frangione, B., Roses, A.D., and Strittmatter, W.J. (1994). Apolipoprotein E associates with amyloid peptide of Alzheimer's disease to form novel monofibrils. J. Clin. Invest. 94, 860-869.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 860-869
-
-
Sanan, D.A.1
Weisgraber, K.H.2
Russell, S.J.3
Mahley, R.W.4
Huang, D.5
Saunders, A.6
Schmechel, D.7
Wisniewski, T.8
Frangione, B.9
Roses, A.D.10
Strittmatter, W.J.11
-
47
-
-
0029073383
-
Genetic dissection of Alzheimer disease, a heterogeneous disorder
-
Schellenberg, G.D. (1995). Genetic dissection of Alzheimer disease, a heterogeneous disorder. Proc. Natl. Acad. Sci. USA 92, 8552-8559.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8552-8559
-
-
Schellenberg, G.D.1
-
48
-
-
0026471656
-
Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14
-
Schellenberg, G.D., Bird, T.D., Wijsman, E.M., Orr, H.T., Anderson, L., Nemens, E., White, J.A., Bonnycastle, L., Weber, J.L., Alonso, M., et al. (1993). Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science 258, 668-671.
-
(1993)
Science
, vol.258
, pp. 668-671
-
-
Schellenberg, G.D.1
Bird, T.D.2
Wijsman, E.M.3
Orr, H.T.4
Anderson, L.5
Nemens, E.6
White, J.A.7
Bonnycastle, L.8
Weber, J.L.9
Alonso, M.10
-
49
-
-
16044373524
-
Secreted amyloid b-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner, D., Eckman, C., Jensen, M., and Younkin, S. (1996). Secreted amyloid b-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nature Medicine 2, 864-870.
-
(1996)
Nature Medicine
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Younkin, S.4
-
50
-
-
0022271553
-
A possible unitary genetic hypothesis for Alzheimer's disease and Down syndrome
-
Schweber, M. (1985). A possible unitary genetic hypothesis for Alzheimer's disease and Down syndrome. Ann. NY Acad. Sci. 450, 223-238.
-
(1985)
Ann. NY Acad. Sci.
, vol.450
, pp. 223-238
-
-
Schweber, M.1
-
51
-
-
0028170818
-
Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease
-
Selkoe, D.J. (1994). Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10, 373-103.
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 373-403
-
-
Selkoe, D.J.1
-
52
-
-
0030779784
-
Skeletal and CNS defects in presenilin-1-deficient mice
-
Shen, J., Bronson, R.T., Chen, D.F., Xia, W., Selkoe, D.J., and Tonegawa, S. (1997). Skeletal and CNS defects in presenilin-1-deficient mice. Cell 89, 629-639.
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
53
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington, R., Rogaev, E.I., Liang, Y., Rogaeva, E.A., Levesque, G., Ikeda, M., Chi, H., Lin, G., Li, G., Holman, K. (1995). Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375, 754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, G.8
Li, G.9
Holman, K.10
-
54
-
-
0029152233
-
Sex chromosome aneuploidy and aging
-
Stone, J.F., and Sandberg, A.A. (1995). Sex chromosome aneuploidy and aging. Mutation Res. 338, 107-113.
-
(1995)
Mutation Res.
, vol.338
, pp. 107-113
-
-
Stone, J.F.1
Sandberg, A.A.2
-
56
-
-
0024356724
-
SPXX, a frequent sequence motif in gene regulatory proteins
-
Suzuki, M. (1989). SPXX, a frequent sequence motif in gene regulatory proteins. J. Mol. Biol. 207, 61-84.
-
(1989)
J. Mol. Biol.
, vol.207
, pp. 61-84
-
-
Suzuki, M.1
-
57
-
-
0030583605
-
Localization of Alzheimer-associated presenilin 1 in transfected COS-7 cells
-
Takashima, A., Sato, M., Mercken, M., Tanaka, S., Kondo, S., Honda, T., Sato, K., Murayama, M., Noguchi, K., Nakazato, Y., and Takahashi, H. (1996). Localization of Alzheimer-associated presenilin 1 in transfected COS-7 cells. Biochem. Biophys. Res. Comm. 227, 423-26.
-
(1996)
Biochem. Biophys. Res. Comm.
, vol.227
, pp. 42326
-
-
Takashima, A.1
Sato, M.2
Mercken, M.3
Tanaka, S.4
Kondo, S.5
Honda, T.6
Sato, K.7
Murayama, M.8
Noguchi, K.9
Nakazato, Y.10
Takahashi, H.11
-
58
-
-
13344293701
-
Presence of soluble amyloid -peptide precedes amyloid plaque formation in Down's syndrome
-
Teller, J.K., Russo, G., DeBusk, L.M., Angelini, G., Zaccheo, D., Dagna-Bricarelli, F., Scartezzini, P., Bertolini, S., Mann, D.M.A., Tabaton, M., and Gambetti, P. (1996). Presence of soluble amyloid -peptide precedes amyloid plaque formation in Down's syndrome. Nature Medicine 2, 93-95.
-
(1996)
Nature Medicine
, vol.2
, pp. 93-95
-
-
Teller, J.K.1
Russo, G.2
Debusk, L.M.3
Angelini, G.4
Zaccheo, D.5
Dagna-Bricarelli, F.6
Scartezzini, P.7
Bertolini, S.8
Mann, D.M.A.9
Tabaton, M.10
Gambetti, P.11
-
59
-
-
15844425969
-
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
Thinakaran, G., Borchelt, D.R., Lee, M.K., Slunt, H.H., Spitzer, L., Kim, G., Slunt, H.H., Spitzer, L., Kim, G., Ratovitsky, T., et al. (1996). Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17, 181-190.
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
Slunt, H.H.7
Spitzer, L.8
Kim, G.9
Ratovitsky, T.10
-
60
-
-
84943438521
-
Anti-centrosome and anti-centriole antibodies in the scleroderma spectrum
-
Tuffanelli, D.L., McKeon, F., Kleinsmith, D.M., Burnham, T.K. and Kirschner, M. (1983). Anti-centrosome and anti-centriole antibodies in the scleroderma spectrum. Arch. Dermatol. 119, 560-566.
-
(1983)
Arch. Dermatol.
, vol.119
, pp. 560-566
-
-
Tuffanelli, D.L.1
McKeon, F.2
Kleinsmith, D.M.3
Burnham, T.K.4
Kirschner, M.5
-
62
-
-
0030062245
-
Mitotic mechanisms in Alzheimer's disease?
-
Vincent, I., Rosado, M., and Davies, P. (1996). Mitotic mechanisms in Alzheimer's disease? J. Cell Biol. 132, 413-425.
-
(1996)
J. Cell Biol.
, vol.132
, pp. 413-425
-
-
Vincent, I.1
Rosado, M.2
Davies, P.3
-
63
-
-
0029671219
-
2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3
-
2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science 271, 521-525.
-
(1996)
Science
, vol.271
, pp. 521-525
-
-
Vito, P.1
Lacana, E.2
D'Adamio, L.3
-
64
-
-
0029856850
-
Requirement of the familial Alzheimer's disease gene PS2 for apoptosis
-
Vito, P., Wolozin, B., Ganjei, J.K., Iwasaki, K., Lacana, E., and D'Adamio, L. (1996b). Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. J. Biol. Chem. 271, 31025-31028.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31025-31028
-
-
Vito, P.1
Wolozin, B.2
Ganjei, J.K.3
Iwasaki, K.4
Lacana, E.5
D'Adamio, L.6
-
65
-
-
8044231311
-
The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum
-
Walter, J., Capell, A., Grünberg, J., Pesold, B., Schindzielorz, A., Prior, R., Podlisny, M.B., Fraser, P., St. George-Hyslop, P., Selkoe, D.J., and Haas, C. (1996). The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum. Mol. Med. 2, 673-691.
-
(1996)
Mol. Med.
, vol.2
, pp. 673-691
-
-
Walter, J.1
Capell, A.2
Grünberg, J.3
Pesold, B.4
Schindzielorz, A.5
Prior, R.6
Podlisny, M.B.7
Fraser, P.8
St George-Hyslop, P.9
Selkoe, D.J.10
Haas, C.11
-
66
-
-
0028047288
-
Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope
-
Westendorf, J.M., Rao, P.N.,and Gerace, L. (1994). Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc. Natl. Acad. Sci. USA 91, 714-718.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 714-718
-
-
Westendorf, J.M.1
Rao, P.N.2
Gerace, L.3
-
67
-
-
0027237823
-
NDC1 : A nuclear periphery component required for yeasts spindle pole body duplication
-
Winey, M., Hoyt, M.A., Chan, C., Goetsch, L., Botstein, D., and Byers, B. (1993). NDC1 : a nuclear periphery component required for yeasts spindle pole body duplication. J. Cell Biol. 122, 743-751.
-
(1993)
J. Cell Biol.
, vol.122
, pp. 743-751
-
-
Winey, M.1
Hoyt, M.A.2
Chan, C.3
Goetsch, L.4
Botstein, D.5
Byers, B.6
-
68
-
-
0027970307
-
Acceleration of Alzheimer's fibril formation byapolipoprotein Ein vitro
-
Wisniewski, T., Castano, E.M., Golabek, A., Vogel, T., and Frangione, B. (1994). Acceleration of Alzheimer's fibril formation byapolipoprotein Ein vitro. Am. J. Pathol. 145, 1030-1035.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1030-1035
-
-
Wisniewski, T.1
Castano, E.M.2
Golabek, A.3
Vogel, T.4
Frangione, B.5
-
69
-
-
10544224542
-
Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation
-
Wolozin, B., Iwasaki, K., Vito, P., Ganjei, J.K., Lacan'a, E., Sunderland, T., Zhao, B., Kusiak, J.W., Wasco, W., D'Adamio, L. (1996). Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science 274, 1710-1713.
-
(1996)
Science
, vol.274
, pp. 1710-1713
-
-
Wolozin, B.1
Iwasaki, K.2
Vito, P.3
Ganjei, J.K.4
Lacan'A, E.5
Sunderland, T.6
Zhao, B.7
Kusiak, J.W.8
Wasco, W.9
D'Adamio, L.10
-
70
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
Yankner, B.A. (1996). Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 16, 921-932.
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
-
71
-
-
0028363978
-
Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane
-
Ye, Q., and Worman, H.J. (1994). Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane. J. Biol. Chem. 269, 11306-11311.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 11306-11311
-
-
Ye, Q.1
Worman, H.J.2
|