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Volumn 237, Issue 2, 1999, Pages 281-302

Regulation of E2F: A family of transcription factors involved in proliferation control

Author keywords

Apoptosis; Cell cycle; Cell growth; Retinoblastoma; Transcription

Indexed keywords

RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

EID: 0032881249     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00305-4     Document Type: Review
Times cited : (108)

References (217)
  • 1
    • 0029973557 scopus 로고    scopus 로고
    • Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors
    • Adams P.D., Sellers W.R., Sharma S.K., Wu A.D., Nalin C.M., Kaelin W.G. Jr. Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol. Cell Biol. 16:1996;6623-6633.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 6623-6633
    • Adams, P.D.1    Sellers, W.R.2    Sharma, S.K.3    Wu, A.D.4    Nalin, C.M.5    Kaelin W.G., Jr.6
  • 2
    • 0028942949 scopus 로고
    • The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter
    • Adnane J., Shao Z., Robbins P.D. The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter. J. Biol. Chem. 270:1995;8837-8843.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8837-8843
    • Adnane, J.1    Shao, Z.2    Robbins, P.D.3
  • 3
    • 0032191333 scopus 로고    scopus 로고
    • Growth inhibition of cultured human Tenon's fibroblastic cells by targeting the E2F transcription factor
    • Akimoto M., Hangai M., Okazaki K., Kogishi J., Honda Y., Kaneda Y. Growth inhibition of cultured human Tenon's fibroblastic cells by targeting the E2F transcription factor. Exp. Eye Res. 67:1998;395-401.
    • (1998) Exp. Eye Res. , vol.67 , pp. 395-401
    • Akimoto, M.1    Hangai, M.2    Okazaki, K.3    Kogishi, J.4    Honda, Y.5    Kaneda, Y.6
  • 4
    • 0030774301 scopus 로고    scopus 로고
    • Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors
    • Allen K.E., de la Luna S., Kerkhoven R.M., Bernards R., La Thangue N.B. Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors. J. Cell Sci. 110:1997;2819-2831.
    • (1997) J. Cell Sci. , vol.110 , pp. 2819-2831
    • Allen, K.E.1    De La Luna, S.2    Kerkhoven, R.M.3    Bernards, R.4    La Thangue, N.B.5
  • 5
    • 0030612740 scopus 로고    scopus 로고
    • PPARγ induces cell cycle withdrawal - Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A
    • Altiok S., Xu M., Spiegelman B.M. PPARγ induces cell cycle withdrawal - inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev. 11:1997;1987-1998.
    • (1997) Genes Dev. , vol.11 , pp. 1987-1998
    • Altiok, S.1    Xu, M.2    Spiegelman, B.M.3
  • 6
    • 0025910802 scopus 로고
    • The retinoblastoma protein copurifies with E2F-1, an E1A-regulated inhibitor of the transcription factor E2F
    • Bagchi S., Weinmann R., Raychaudhuri P. The retinoblastoma protein copurifies with E2F-1, an E1A-regulated inhibitor of the transcription factor E2F. Cell. 65:1991;1063-1072.
    • (1991) Cell , vol.65 , pp. 1063-1072
    • Bagchi, S.1    Weinmann, R.2    Raychaudhuri, P.3
  • 7
    • 0025869428 scopus 로고
    • Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor
    • Bandara L.R., La Thangue N.B. Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature. 351:1991;494-497.
    • (1991) Nature , vol.351 , pp. 494-497
    • Bandara, L.R.1    La Thangue, N.B.2
  • 8
    • 0028334543 scopus 로고
    • DP-1: A cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein
    • Bandara L.R., Lam E.W., Sorensen T.S., Zamanian M., Girling R., La Thangue N.B. DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein. EMBO J. 13:1994;3104-3114.
    • (1994) EMBO J. , vol.13 , pp. 3104-3114
    • Bandara, L.R.1    Lam, E.W.2    Sorensen, T.S.3    Zamanian, M.4    Girling, R.5    La Thangue, N.B.6
  • 9
    • 0030828488 scopus 로고    scopus 로고
    • Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor
    • Bandara L.R., Girling R., La Thangue N.B. Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor. Nature Biotechnol. 15:1997;896-901.
    • (1997) Nature Biotechnol. , vol.15 , pp. 896-901
    • Bandara, L.R.1    Girling, R.2    La Thangue, N.B.3
  • 10
    • 0029913676 scopus 로고    scopus 로고
    • Blocking the transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in SCID mice
    • Bargou R.C., Wagener C., Bommert K., Arnold W., Daniel P.T., Mapara M.Y., Grinstein E., Royer H.D., Dorken B. Blocking the transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in SCID mice. J. Exp. Med. 183:1996;1205-1213.
    • (1996) J. Exp. Med. , vol.183 , pp. 1205-1213
    • Bargou, R.C.1    Wagener, C.2    Bommert, K.3    Arnold, W.4    Daniel, P.T.5    Mapara, M.Y.6    Grinstein, E.7    Royer, H.D.8    Dorken, B.9
  • 11
    • 0028785753 scopus 로고
    • Strain-dependent differences in DNA synthesis and gene expression in the regenerating livers of CB57BL/6J and C3H/HeJ mice
    • Bennett L.M., Farnham P.J., Drinkwater N.R. Strain-dependent differences in DNA synthesis and gene expression in the regenerating livers of CB57BL/6J and C3H/HeJ mice. Mol. Carcinogen. 14:1995;46-52.
    • (1995) Mol. Carcinogen. , vol.14 , pp. 46-52
    • Bennett, L.M.1    Farnham, P.J.2    Drinkwater, N.R.3
  • 12
    • 0029781223 scopus 로고    scopus 로고
    • E2F binding is required but not sufficient for repression of B-myb transcription in quiescent fibroblasts
    • Bennett J.D., Farlie P.G., Watson R.J. E2F binding is required but not sufficient for repression of B-myb transcription in quiescent fibroblasts. Oncogene. 13:1996;1073-1082.
    • (1996) Oncogene , vol.13 , pp. 1073-1082
    • Bennett, J.D.1    Farlie, P.G.2    Watson, R.J.3
  • 15
    • 0033555521 scopus 로고    scopus 로고
    • Growth/cell cycle regulation of Sp1 phosphorylation
    • Black A.R., Jensen D., Lin S.Y., Azizkhan J.C. Growth/cell cycle regulation of Sp1 phosphorylation. J. Biol. Chem. 274:1999;1207-1215.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1207-1215
    • Black, A.R.1    Jensen, D.2    Lin, S.Y.3    Azizkhan, J.C.4
  • 16
    • 0024318029 scopus 로고
    • Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo
    • Blake M.C., Azizkhan J.C. Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo. Mol. Cell Biol. 9:1989;4994-5002.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 4994-5002
    • Blake, M.C.1    Azizkhan, J.C.2
  • 17
    • 0032939925 scopus 로고    scopus 로고
    • Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
    • Blattner C., Sparks A., Lane D. Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol. Cell Biol. 19:1999;3704-3713.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 3704-3713
    • Blattner, C.1    Sparks, A.2    Lane, D.3
  • 21
    • 0033559609 scopus 로고    scopus 로고
    • Neural precursor cells differentiating in the absence of RB exhibit delayed terminal mitosis and deregulated E2F-1 and -3 activity
    • Callaghan D.A., Dong L., Callaghan S.M., Hou Y.X., Dagnino L., Slack R.S. Neural precursor cells differentiating in the absence of RB exhibit delayed terminal mitosis and deregulated E2F-1 and -3 activity. Dev. Biol. 207:1999;257-270.
    • (1999) Dev. Biol. , vol.207 , pp. 257-270
    • Callaghan, D.A.1    Dong, L.2    Callaghan, S.M.3    Hou, Y.X.4    Dagnino, L.5    Slack, R.S.6
  • 22
    • 0030903750 scopus 로고    scopus 로고
    • Regulation of E2F through ubiquitin-proteasome-dependent degradation - Stabilization by the pRB tumor suppressor protein
    • Campanero M.R., Flemington E.K. Regulation of E2F through ubiquitin-proteasome-dependent degradation - stabilization by the pRB tumor suppressor protein. Proc. Natl. Acad. Sci. USA. 94:1997;2221-2226.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2221-2226
    • Campanero, M.R.1    Flemington, E.K.2
  • 23
    • 0032490832 scopus 로고    scopus 로고
    • E2F-6: A novel member of the E2F family is an inhibitor of E2F-dependent transcription
    • Cartwright P., Muller H., Wagener C., Holm K., Helin K. E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene. 17:1998;611-623.
    • (1998) Oncogene , vol.17 , pp. 611-623
    • Cartwright, P.1    Muller, H.2    Wagener, C.3    Holm, K.4    Helin, K.5
  • 24
    • 0025905183 scopus 로고
    • The E2F transcription factor is a cellular target for the RB protein
    • Chellappan S.P., Hiebert S., Mudryj M., Horowitz J.M., Nevins J.R. The E2F transcription factor is a cellular target for the RB protein. Cell. 65:1991;1053-1061.
    • (1991) Cell , vol.65 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.2    Mudryj, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 27
    • 0025734783 scopus 로고
    • The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
    • Chittenden T., Livingston D.M., Kaelin W.G. Jr. The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell. 65:1991;1073-1082.
    • (1991) Cell , vol.65 , pp. 1073-1082
    • Chittenden, T.1    Livingston, D.M.2    Kaelin W.G., Jr.3
  • 29
    • 0030750887 scopus 로고    scopus 로고
    • Inhibition of E2F-4/DP-1-stimulated transcription by p202
    • Choubey D., Gutterman J.U. Inhibition of E2F-4/DP-1-stimulated transcription by p202. Oncogene. 15:1997;291-301.
    • (1997) Oncogene , vol.15 , pp. 291-301
    • Choubey, D.1    Gutterman, J.U.2
  • 30
    • 0029762617 scopus 로고    scopus 로고
    • Domains A and B in the Rb pocket interact to form a transcriptional repressor motif
    • Chow K.N., Dean D.C. Domains A and B in the Rb pocket interact to form a transcriptional repressor motif. Mol. Cell Biol. 16:1996;4862-4868.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4862-4868
    • Chow, K.N.1    Dean, D.C.2
  • 31
    • 0029880350 scopus 로고    scopus 로고
    • A role for a bent DNA structure in E2F-mediated transcription activation
    • Cress W.D., Nevins J.R. A role for a bent DNA structure in E2F-mediated transcription activation. Mol. Cell Biol. 16:1996;2119-2127.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 2119-2127
    • Cress, W.D.1    Nevins, J.R.2
  • 32
    • 0031958724 scopus 로고    scopus 로고
    • Differential transcriptional activation by the N-terminal region of BRCA1 splice variants BRCA1a and BRCA1b
    • Cui J.Q., Wang H., Reddy E.S., Rao V.N. Differential transcriptional activation by the N-terminal region of BRCA1 splice variants BRCA1a and BRCA1b. Oncol. Rep. 5:1998;585-589.
    • (1998) Oncol. Rep. , vol.5 , pp. 585-589
    • Cui, J.Q.1    Wang, H.2    Reddy, E.S.3    Rao, V.N.4
  • 33
    • 0030959767 scopus 로고    scopus 로고
    • Expression patterns of the E2F family of transcription factors during mouse nervous system development
    • Dagnino L., Fry C.J., Bartley S.M., Farnham P., Gallie B.L., Phillips R.A. Expression patterns of the E2F family of transcription factors during mouse nervous system development. Mech. Dev. 66:1997;13-25.
    • (1997) Mech. Dev. , vol.66 , pp. 13-25
    • Dagnino, L.1    Fry, C.J.2    Bartley, S.M.3    Farnham, P.4    Gallie, B.L.5    Phillips, R.A.6
  • 34
    • 0030991285 scopus 로고    scopus 로고
    • Expression patterns of the E2F family of transcription factors during murine epithelial development
    • Dagnino L., Fry C.J., Bartley S.M., Farnham P., Gallie B.L., Phillips R.A. Expression patterns of the E2F family of transcription factors during murine epithelial development. Cell Growth Differ. 8:1997;553-563.
    • (1997) Cell Growth Differ. , vol.8 , pp. 553-563
    • Dagnino, L.1    Fry, C.J.2    Bartley, S.M.3    Farnham, P.4    Gallie, B.L.5    Phillips, R.A.6
  • 36
    • 0029912789 scopus 로고    scopus 로고
    • Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal
    • de la Luna S., Burden M.J., Lee C.W., La Thangue N.B. Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal. J. Cell Sci. 109:1996;2443-2452.
    • (1996) J. Cell Sci. , vol.109 , pp. 2443-2452
    • De La Luna, S.1    Burden, M.J.2    Lee, C.W.3    La Thangue, N.B.4
  • 37
    • 0033521615 scopus 로고    scopus 로고
    • Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor
    • de la Luna S., Allen K.E., Mason S.L., La Thangue N.B. Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor. EMBO J. 18:1999;212-228.
    • (1999) EMBO J. , vol.18 , pp. 212-228
    • De La Luna, S.1    Allen, K.E.2    Mason, S.L.3    La Thangue, N.B.4
  • 39
    • 0031803929 scopus 로고    scopus 로고
    • Retinoblastoma protein tethered to promoter DNA represses TBP-mediated transcription
    • De Luca P., Majello B., Lania L. Retinoblastoma protein tethered to promoter DNA represses TBP-mediated transcription. J. Cell Biochem. 70:1998;281-287.
    • (1998) J. Cell Biochem. , vol.70 , pp. 281-287
    • De Luca, P.1    Majello, B.2    Lania, L.3
  • 40
    • 0033537977 scopus 로고    scopus 로고
    • Two E2F sites control growth-regulated and cell cycle-regulated transcription of the Htf9-a/RanBP1 gene through functionally distinct mechanisms
    • Di Fiore B., Guarguaglini G., Palena A., Kerkhoven R.M., Bernards R., Lavia P. Two E2F sites control growth-regulated and cell cycle-regulated transcription of the Htf9-a/RanBP1 gene through functionally distinct mechanisms. J. Biol. Chem. 274:1999;10339-10348.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10339-10348
    • Di Fiore, B.1    Guarguaglini, G.2    Palena, A.3    Kerkhoven, R.M.4    Bernards, R.5    Lavia, P.6
  • 41
    • 0032551995 scopus 로고    scopus 로고
    • The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells
    • Dirks P.B., Rutka J.T., Hubbard S.L., Mondal S., Hamel P.A. The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells. Oncogene. 17:1998;867-876.
    • (1998) Oncogene , vol.17 , pp. 867-876
    • Dirks, P.B.1    Rutka, J.T.2    Hubbard, S.L.3    Mondal, S.4    Hamel, P.A.5
  • 42
  • 43
    • 0032518492 scopus 로고    scopus 로고
    • Developmental pattern of expression of NPDC-1 and its interaction with E2F-1 suggest a role in the control of proliferation and differentiation of neural cells
    • Dupont E., Sansal I., Evrard C., Rouget P. Developmental pattern of expression of NPDC-1 and its interaction with E2F-1 suggest a role in the control of proliferation and differentiation of neural cells. J. Neurosci. Res. 51:1998;257-267.
    • (1998) J. Neurosci. Res. , vol.51 , pp. 257-267
    • Dupont, E.1    Sansal, I.2    Evrard, C.3    Rouget, P.4
  • 45
    • 0027936686 scopus 로고
    • Differential regulation of E2F transactivation by cyclin/cdk2 complexes
    • Dynlacht B.D., Flores O., Lees J.A., Harlow E. Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev. 8:1994;1772-1786.
    • (1994) Genes Dev. , vol.8 , pp. 1772-1786
    • Dynlacht, B.D.1    Flores, O.2    Lees, J.A.3    Harlow, E.4
  • 46
    • 0030768779 scopus 로고    scopus 로고
    • Regulation of transcription by proteins that control the cell cycle
    • Dynlacht B.D. Regulation of transcription by proteins that control the cell cycle. Nature. 389:1997;149-152.
    • (1997) Nature , vol.389 , pp. 149-152
    • Dynlacht, B.D.1
  • 47
    • 0030990095 scopus 로고    scopus 로고
    • Specific regulation of E2F family members by cyclin-dependent kinases
    • Dynlacht B.D., Moberg K., Lees J.A., Harlow E., Zhu L. Specific regulation of E2F family members by cyclin-dependent kinases. Mol. Cell Biol. 17:1997;3867-3875.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 3867-3875
    • Dynlacht, B.D.1    Moberg, K.2    Lees, J.A.3    Harlow, E.4    Zhu, L.5
  • 48
    • 0029015262 scopus 로고
    • Promoter-dependent photocross-linking of the acidic transcriptional activator E2F-1 to the TATA-binding protein
    • Emili A., Ingles C.J. Promoter-dependent photocross-linking of the acidic transcriptional activator E2F-1 to the TATA-binding protein. J. Biol. Chem. 270:1995;13674-13680.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13674-13680
    • Emili, A.1    Ingles, C.J.2
  • 49
    • 0031609235 scopus 로고    scopus 로고
    • Regulation of the cell cycle by the Rb tumor suppressor family
    • Ewen M.E. Regulation of the cell cycle by the Rb tumor suppressor family. Results Probl. Cell Differ. 22:1998;149-179.
    • (1998) Results Probl. Cell Differ. , vol.22 , pp. 149-179
    • Ewen, M.E.1
  • 50
    • 0027936238 scopus 로고
    • Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein
    • Fagan R., Flint K.J., Jones N. Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein. Cell. 78:1994;799-811.
    • (1994) Cell , vol.78 , pp. 799-811
    • Fagan, R.1    Flint, K.J.2    Jones, N.3
  • 51
    • 0030970016 scopus 로고    scopus 로고
    • Functional roles of E2F in cell cycle regulation
    • Fan J.G., Bertino J.R. Functional roles of E2F in cell cycle regulation. Oncogene. 14:1997;1191-1200.
    • (1997) Oncogene , vol.14 , pp. 1191-1200
    • Fan, J.G.1    Bertino, J.R.2
  • 52
    • 0021812170 scopus 로고
    • Transcriptional regulation of mouse dihydrofolate reductase in the cell cycle
    • Farnham P.J., Schimke R.T. Transcriptional regulation of mouse dihydrofolate reductase in the cell cycle. J. Biol. Chem. 260:1985;7675-7680.
    • (1985) J. Biol. Chem. , vol.260 , pp. 7675-7680
    • Farnham, P.J.1    Schimke, R.T.2
  • 53
    • 0032168984 scopus 로고    scopus 로고
    • The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase
    • Ferreira R., Magnaghi-Jaulin L., Robin P., Harel-Bellan A., Trouche D. The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase. Proc. Natl. Acad. Sci. USA. 95:1998;10493-10498.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10493-10498
    • Ferreira, R.1    Magnaghi-Jaulin, L.2    Robin, P.3    Harel-Bellan, A.4    Trouche, D.5
  • 55
    • 0032510270 scopus 로고    scopus 로고
    • E2F-3 accumulation is regulated by polypeptide stability
    • Flores A.M., Kassatly R.F., Cress W.D. E2F-3 accumulation is regulated by polypeptide stability. Oncogene. 16:1998;1289-1298.
    • (1998) Oncogene , vol.16 , pp. 1289-1298
    • Flores, A.M.1    Kassatly, R.F.2    Cress, W.D.3
  • 57
    • 0030943297 scopus 로고    scopus 로고
    • Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain
    • Fry C.J., Slansky J.E., Farnham P.J. Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain. Mol. Cell Biol. 17:1997;1966-1976.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 1966-1976
    • Fry, C.J.1    Slansky, J.E.2    Farnham, P.J.3
  • 60
    • 0032482981 scopus 로고    scopus 로고
    • Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6
    • Gaubatz S., Wood J.G., Livingston D.M. Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc. Natl. Acad. Sci. USA. 95:1998;9190-9195.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9190-9195
    • Gaubatz, S.1    Wood, J.G.2    Livingston, D.M.3
  • 61
    • 0032192140 scopus 로고    scopus 로고
    • The complexity of p53 modulation: Emerging patterns from divergent signals
    • Giaccia A.J., Kastan M.B. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12:1998;2973-2983.
    • (1998) Genes Dev. , vol.12 , pp. 2973-2983
    • Giaccia, A.J.1    Kastan, M.B.2
  • 63
    • 0030625679 scopus 로고    scopus 로고
    • The multifunctional role of the co-activator CBP in transcriptional regulation
    • Goldman P.S., Tran V.K., Goodman R.H. The multifunctional role of the co-activator CBP in transcriptional regulation. Recent Progr. Horm. Res. 52:1997;103-119.
    • (1997) Recent Progr. Horm. Res. , vol.52 , pp. 103-119
    • Goldman, P.S.1    Tran, V.K.2    Goodman, R.H.3
  • 64
    • 0032437776 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth
    • Grana X., Garriga J., Mayol X. Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth. Oncogene. 17:1998;3365-3383.
    • (1998) Oncogene , vol.17 , pp. 3365-3383
    • Grana, X.1    Garriga, J.2    Mayol, X.3
  • 66
    • 0030031542 scopus 로고    scopus 로고
    • E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytes
    • Guy C.T., Zhou W., Kaufman S., Robinson M.O. E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytes. Mol. Cell Biol. 16:1996;685-693.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 685-693
    • Guy, C.T.1    Zhou, W.2    Kaufman, S.3    Robinson, M.O.4
  • 68
    • 0027520469 scopus 로고
    • The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro
    • Hagemeier C., Cook A., Kouzarides T. The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro. Nucleic Acids Res. 21:1993;4998-5004.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4998-5004
    • Hagemeier, C.1    Cook, A.2    Kouzarides, T.3
  • 69
    • 0029797841 scopus 로고    scopus 로고
    • Degradation of E2F by the ubiquitin-proteasome pathway, regulation by retinoblastoma family proteins and adenovirus transforming proteins
    • Hateboer G., Kerkhoven R.M., Shvarts A., Bernards R., Beijersbergen R.L. Degradation of E2F by the ubiquitin-proteasome pathway, regulation by retinoblastoma family proteins and adenovirus transforming proteins. Genes Dev. 10:1996;2960-2970.
    • (1996) Genes Dev. , vol.10 , pp. 2960-2970
    • Hateboer, G.1    Kerkhoven, R.M.2    Shvarts, A.3    Bernards, R.4    Beijersbergen, R.L.5
  • 70
    • 0028318194 scopus 로고
    • Different regulation of thymidine kinase during the cell cycle of normal versus DNA tumor virus-transformed cells
    • Hengstschlager M., Knofler M., Mullner E.W., Ogris E., Wintersberger E., Wawra E. Different regulation of thymidine kinase during the cell cycle of normal versus DNA tumor virus-transformed cells. J. Biol. Chem. 269:1994;13836-13842.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13836-13842
    • Hengstschlager, M.1    Knofler, M.2    Mullner, E.W.3    Ogris, E.4    Wintersberger, E.5    Wawra, E.6
  • 71
    • 0033590621 scopus 로고    scopus 로고
    • Different regulation of c-Myc and E2F-1-induced apoptosis during the ongoing cell cycle
    • Hengstschlager M., Holzl G., Hengstschlager-Ottnad E. Different regulation of c-Myc and E2F-1-induced apoptosis during the ongoing cell cycle. Oncogene. 18:1999;843-848.
    • (1999) Oncogene , vol.18 , pp. 843-848
    • Hengstschlager, M.1    Holzl, G.2    Hengstschlager-Ottnad, E.3
  • 72
    • 0024670325 scopus 로고
    • E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor
    • Hiebert S.W., Lipp M., Nevins J.R. E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. Proc. Natl. Acad. Sci. USA. 86:1989;3594-3598.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3594-3598
    • Hiebert, S.W.1    Lipp, M.2    Nevins, J.R.3
  • 73
    • 0032568323 scopus 로고    scopus 로고
    • Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F
    • Hiyama H., Iavarone A., Reeves S.A. Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F. Oncogene. 16:1998;1513-1523.
    • (1998) Oncogene , vol.16 , pp. 1513-1523
    • Hiyama, H.1    Iavarone, A.2    Reeves, S.A.3
  • 74
    • 0345299171 scopus 로고    scopus 로고
    • Increased levels of E2F-1-dependent DNA binding activity after UV- Or gamma-irradiation
    • Hofferer M., Wirbelauer C., Humar B., Krek W. Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation. Nucleic Acids Res. 27:1999;491-495.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 491-495
    • Hofferer, M.1    Wirbelauer, C.2    Humar, B.3    Krek, W.4
  • 76
    • 0029820095 scopus 로고    scopus 로고
    • The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
    • Hofmann F., Martelli F., Livingston D.M., Wang Z. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 10:1996;2949-2959.
    • (1996) Genes Dev. , vol.10 , pp. 2949-2959
    • Hofmann, F.1    Martelli, F.2    Livingston, D.M.3    Wang, Z.4
  • 77
    • 0030850752 scopus 로고    scopus 로고
    • E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
    • Hsieh J.K., Fredersdorf S., Kouzarides T., Martin K., Lu X. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev. 11:1997;1840-1852.
    • (1997) Genes Dev. , vol.11 , pp. 1840-1852
    • Hsieh, J.K.1    Fredersdorf, S.2    Kouzarides, T.3    Martin, K.4    Lu, X.5
  • 81
    • 0028359441 scopus 로고
    • Retinoblastoma protein reverses DNA bending by transcription factor E2F
    • Huber H.E., Goodhart P.J., Huang P.S. Retinoblastoma protein reverses DNA bending by transcription factor E2F. J. Biol. Chem. 269:1994;6999-7005.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6999-7005
    • Huber, H.E.1    Goodhart, P.J.2    Huang, P.S.3
  • 82
    • 15444353328 scopus 로고    scopus 로고
    • PRb and p107/p130 are required for the regulated expression of different sets of E2F responsive genes
    • Hurford R.K., Cobrinik D., Lee M.H., Dyson N. pRb and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev. 11:1997;1447-1463.
    • (1997) Genes Dev. , vol.11 , pp. 1447-1463
    • Hurford, R.K.1    Cobrinik, D.2    Lee, M.H.3    Dyson, N.4
  • 83
    • 0029868367 scopus 로고    scopus 로고
    • A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation
    • Ikeda M.A., Jakoi L., Nevins J.R. A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc. Natl. Acad. Sci. USA. 93:1996;3215-3220.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3215-3220
    • Ikeda, M.A.1    Jakoi, L.2    Nevins, J.R.3
  • 84
    • 0030931381 scopus 로고    scopus 로고
    • Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter
    • Jensen D.E., Black A.R., Swick A.G., Azizkhan J.C. Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter. J. Cell Biochem. 67:1997;24-31.
    • (1997) J. Cell Biochem. , vol.67 , pp. 24-31
    • Jensen, D.E.1    Black, A.R.2    Swick, A.G.3    Azizkhan, J.C.4
  • 87
    • 0029926303 scopus 로고    scopus 로고
    • Interaction of Sp1 with the growth- And cell cycle-regulated transcription factor E2F
    • Karlseder J., Rotheneder H., Wintersberger E. Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F. Mol. Cell Biol. 16:1996;1659-1667.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 1659-1667
    • Karlseder, J.1    Rotheneder, H.2    Wintersberger, E.3
  • 89
    • 0031945458 scopus 로고    scopus 로고
    • Cell cycle regulation and apoptosis
    • King K.L., Cidlowski J.A. Cell cycle regulation and apoptosis. Ann. Rev. Physiol. 60:1998;601-617.
    • (1998) Ann. Rev. Physiol. , vol.60 , pp. 601-617
    • King, K.L.1    Cidlowski, J.A.2
  • 92
    • 0022454147 scopus 로고
    • Identification of a cellular transcription factor involved in E1A trans-activation
    • Kovesdi I., Reichel R., Nevins J.R. Identification of a cellular transcription factor involved in E1A trans-activation. Cell. 45:1986;219-228.
    • (1986) Cell , vol.45 , pp. 219-228
    • Kovesdi, I.1    Reichel, R.2    Nevins, J.R.3
  • 93
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • Kowalik T.F., DeGregori J., Schwarz J.K., Nevins J.R. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol. 69:1995;2491-2500.
    • (1995) J. Virol. , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    DeGregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 94
    • 0031992159 scopus 로고    scopus 로고
    • E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
    • Kowalik T.F., DeGregori J., Leone G., Jakoi L., Nevins J.R. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ. 9:1998;113-118.
    • (1998) Cell Growth Differ. , vol.9 , pp. 113-118
    • Kowalik, T.F.1    DeGregori, J.2    Leone, G.3    Jakoi, L.4    Nevins, J.R.5
  • 95
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek W., Ewen M.E., Shirodkar S., Arany Z., Kaelin W.G. Jr., Livingston D.M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell. 78:1994;161-172.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin W.G., Jr.5    Livingston, D.M.6
  • 96
    • 0029559027 scopus 로고
    • Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S-phase checkpoint
    • Krek W., Xu G., Livingston D.M. Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S-phase checkpoint. Cell. 83:1995;1149-1158.
    • (1995) Cell , vol.83 , pp. 1149-1158
    • Krek, W.1    Xu, G.2    Livingston, D.M.3
  • 98
    • 0027316813 scopus 로고
    • An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
    • Lam E.W., Watson R.J. An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J. 12:1993;2705-2713.
    • (1993) EMBO J. , vol.12 , pp. 2705-2713
    • Lam, E.W.1    Watson, R.J.2
  • 99
    • 0032936349 scopus 로고    scopus 로고
    • Transcriptional control by cell-cycle regulators: A review
    • Lania L., Majello B., Napolitano G. Transcriptional control by cell-cycle regulators: a review. J. Cell Physiol. 179:1999;134-141.
    • (1999) J. Cell Physiol. , vol.179 , pp. 134-141
    • Lania, L.1    Majello, B.2    Napolitano, G.3
  • 101
    • 0032433267 scopus 로고    scopus 로고
    • Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene
    • LeCouter J.E., Kablar B., Whyte P.F., Ying C., Rudnicki M.A. Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene. Development. 125:1998;4669-4679.
    • (1998) Development , vol.125 , pp. 4669-4679
    • Lecouter, J.E.1    Kablar, B.2    Whyte, P.F.3    Ying, C.4    Rudnicki, M.A.5
  • 102
    • 0032575079 scopus 로고    scopus 로고
    • Functional interplay between p53 and E2F through co-activator p300
    • Lee C.W., Sorensen T.S., Shikama N., Lathangue N.B. Functional interplay between p53 and E2F through co-activator p300. Oncogene. 16:1998;2695-2710.
    • (1998) Oncogene , vol.16 , pp. 2695-2710
    • Lee, C.W.1    Sorensen, T.S.2    Shikama, N.3    Lathangue, N.B.4
  • 103
    • 0032528027 scopus 로고    scopus 로고
    • E2F3 activity is regulated during the cell cycle and is required for the induction of S-phase
    • Leone G., DeGregori J., Yan Z., Jakoi L., Ishida S., Williams R.S., Nevins J.R. E2F3 activity is regulated during the cell cycle and is required for the induction of S-phase. Genes Dev. 12:1998;2120-2130.
    • (1998) Genes Dev. , vol.12 , pp. 2120-2130
    • Leone, G.1    DeGregori, J.2    Yan, Z.3    Jakoi, L.4    Ishida, S.5    Williams, R.S.6    Nevins, J.R.7
  • 104
    • 0030610390 scopus 로고    scopus 로고
    • waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells
    • waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells. Cancer Res. 57:1997;2193-2199.
    • (1997) Cancer Res. , vol.57 , pp. 2193-2199
    • Li, W.W.1    Fan, J.G.2    Hochhauser, D.3    Bertino, J.R.4
  • 105
    • 0029981560 scopus 로고    scopus 로고
    • Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction
    • Lin S.-Y., Black A.R., Kostic A., Pajovic S., Hoover C.N., Azizkhan J.C. Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction. Mol. Cell Biol. 16:1996;1668-1675.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 1668-1675
    • Lin, S.-Y.1    Black, A.R.2    Kostic, A.3    Pajovic, S.4    Hoover, C.N.5    Azizkhan, J.C.6
  • 108
    • 0030038279 scopus 로고    scopus 로고
    • Cell cycle-regulated repression of B-myb transcription: Cooperation of an E2F site with a contiguous corepressor element
    • Liu N., Lucibello F.C., Zwicker J., Engeland K., Muller R. Cell cycle-regulated repression of B-myb transcription: cooperation of an E2F site with a contiguous corepressor element. Nucleic Acids Res. 24:1996;2905-2910.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2905-2910
    • Liu, N.1    Lucibello, F.C.2    Zwicker, J.3    Engeland, K.4    Muller, R.5
  • 109
    • 0032507880 scopus 로고    scopus 로고
    • A new model of cell cycle-regulated transcription: Repression of the cyclin A promoter by CDF-1 and anti-repression by E2F
    • Liu N., Lucibello F.C., Engeland K., Muller R. A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F. Oncogene. 16:1998;2957-2963.
    • (1998) Oncogene , vol.16 , pp. 2957-2963
    • Liu, N.1    Lucibello, F.C.2    Engeland, K.3    Muller, R.4
  • 110
    • 0031304178 scopus 로고    scopus 로고
    • Molecular cloning and expression pattern of the DP members of the chicken E2F transcription factor
    • Loiseau L., Pasteau S., Brun G. Molecular cloning and expression pattern of the DP members of the chicken E2F transcription factor. Gene Expr. 6:1997;259-273.
    • (1997) Gene Expr. , vol.6 , pp. 259-273
    • Loiseau, L.1    Pasteau, S.2    Brun, G.3
  • 112
    • 0032549001 scopus 로고    scopus 로고
    • Rb interacts with histone deacetylase to repress transcription
    • Luo R.X., Postigo A.A., Dean D.C. Rb interacts with histone deacetylase to repress transcription. Cell. 92:1998;463-473.
    • (1998) Cell , vol.92 , pp. 463-473
    • Luo, R.X.1    Postigo, A.A.2    Dean, D.C.3
  • 113
    • 0029910628 scopus 로고    scopus 로고
    • Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
    • Macleod K.F., Hu Y.W., Jacks T. Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J. 15:1996;6178-6188.
    • (1996) EMBO J. , vol.15 , pp. 6178-6188
    • Macleod, K.F.1    Hu, Y.W.2    Jacks, T.3
  • 115
    • 0029991715 scopus 로고    scopus 로고
    • Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members
    • Magae J., Wu C.L., Illenye S., Harlow E., Heintz N.H. Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members. J. Cell Sci. 109:1996;1717-1726.
    • (1996) J. Cell Sci. , vol.109 , pp. 1717-1726
    • Magae, J.1    Wu, C.L.2    Illenye, S.3    Harlow, E.4    Heintz, N.H.5
  • 116
    • 0033590634 scopus 로고    scopus 로고
    • Association with E2F-1 governs intracellular trafficking and polyubiquitination of DP-1
    • Magae J., Illenye S., Chang Y.C., Mitsui Y., Heintz N.H. Association with E2F-1 governs intracellular trafficking and polyubiquitination of DP-1. Oncogene. 18:1999;593-605.
    • (1999) Oncogene , vol.18 , pp. 593-605
    • Magae, J.1    Illenye, S.2    Chang, Y.C.3    Mitsui, Y.4    Heintz, N.H.5
  • 118
    • 0027461130 scopus 로고
    • Identification of a protein from Saccharomyces cerevisiae with E2F-like DNA-binding and transactivating properties
    • Mai B., Lipp M. Identification of a protein from Saccharomyces cerevisiae with E2F-like DNA-binding and transactivating properties. FEBS Lett. 321:1993;153-158.
    • (1993) FEBS Lett. , vol.321 , pp. 153-158
    • Mai, B.1    Lipp, M.2
  • 119
    • 0029002696 scopus 로고
    • Differential transcriptional regulation of c-myc promoter through the same DNA binding sites targeted by Sp1-like proteins
    • Majello B., De Luca P., Suske G., Lania L. Differential transcriptional regulation of c-myc promoter through the same DNA binding sites targeted by Sp1-like proteins. Oncogene. 10:1995;1841-1848.
    • (1995) Oncogene , vol.10 , pp. 1841-1848
    • Majello, B.1    De Luca, P.2    Suske, G.3    Lania, L.4
  • 120
    • 0033020484 scopus 로고    scopus 로고
    • Regulation of endogenous E2F1 stability by the retinoblastoma family proteins
    • Martelli F., Livingston D.M. Regulation of endogenous E2F1 stability by the retinoblastoma family proteins. Proc. Natl. Acad. Sci. USA. 96:1999;2858-2863.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2858-2863
    • Martelli, F.1    Livingston, D.M.2
  • 122
    • 0032622050 scopus 로고    scopus 로고
    • P53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin
    • Meng R.D., Phillips P., El-Deiry W.S. p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin. Int. J. Oncol. 14:1999;5-14.
    • (1999) Int. J. Oncol. , vol.14 , pp. 5-14
    • Meng, R.D.1    Phillips, P.2    El-Deiry, W.S.3
  • 123
    • 0029978325 scopus 로고    scopus 로고
    • E2F-4 switches from p130 to p107 and pRB in response to cell cycle re-entry
    • Moberg K., Starz M.A., Lees J.A. E2F-4 switches from p130 to p107 and pRB in response to cell cycle re-entry. Mol. Cell Biol. 16:1996;1436-1449.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 1436-1449
    • Moberg, K.1    Starz, M.A.2    Lees, J.A.3
  • 126
    • 0025893161 scopus 로고
    • Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A
    • Mudryj M., Devoto S.H., Hiebert S.W., Hunter T., Pines J., Nevins J.R. Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell. 65:1991;1243-1253.
    • (1991) Cell , vol.65 , pp. 1243-1253
    • Mudryj, M.1    Devoto, S.H.2    Hiebert, S.W.3    Hunter, T.4    Pines, J.5    Nevins, J.R.6
  • 127
    • 0039227088 scopus 로고    scopus 로고
    • Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
    • Muller H., Moroni M.C., Vigo E., Petersen B.O., Bartek J., Helin K. Induction of S-phase entry by E2F transcription factors depends on their nuclear localization. Mol. Cell Biol. 17:1997;5508-5520.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 5508-5520
    • Muller, H.1    Moroni, M.C.2    Vigo, E.3    Petersen, B.O.4    Bartek, J.5    Helin, K.6
  • 128
    • 0028136903 scopus 로고
    • Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA binding within its own promoter
    • Neuman E., Flemington E.K., Sellers W.R., Kaelin W.G. Jr. Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA binding within its own promoter. Mol. Cell Biol. 14:1994;6607-6615.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6607-6615
    • Neuman, E.1    Flemington, E.K.2    Sellers, W.R.3    Kaelin W.G., Jr.4
  • 129
    • 0028008441 scopus 로고
    • Cell cycle targets of the DNA tumor viruses
    • Nevins J.R. Cell cycle targets of the DNA tumor viruses. Curr. Opin. Genet. Dev. 4:1994;130-134.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 130-134
    • Nevins, J.R.1
  • 131
    • 0029615315 scopus 로고
    • Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1
    • O'Connor D.J., Lam E.W., Griffin S., Zhong S., Leighton L.C., Burbidge S.A., Lu X. Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1. EMBO J. 14:1995;6184-6192.
    • (1995) EMBO J. , vol.14 , pp. 6184-6192
    • O'Connor, D.J.1    Lam, E.W.2    Griffin, S.3    Zhong, S.4    Leighton, L.C.5    Burbidge, S.A.6    Lu, X.7
  • 133
    • 0029860820 scopus 로고    scopus 로고
    • Expression of the HsORC1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor
    • Ohtani K., DeGregori J., Leone G., Herendeen D.R., Kelly T.J., Nevins J.R. Expression of the HsORC1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Mol. Cell Biol. 16:1996;6977-6984.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 6977-6984
    • Ohtani, K.1    DeGregori, J.2    Leone, G.3    Herendeen, D.R.4    Kelly, T.J.5    Nevins, J.R.6
  • 135
    • 0028787278 scopus 로고
    • A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F
    • Ormondroyd E., de la Luna S., La Thangue N.B. A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F. Oncogene. 11:1995;1437-1446.
    • (1995) Oncogene , vol.11 , pp. 1437-1446
    • Ormondroyd, E.1    De La Luna, S.2    La Thangue, N.B.3
  • 136
    • 0030820932 scopus 로고    scopus 로고
    • Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins
    • Pajovic S., Wong E.L., Black A.R., Azizkhan J.C. Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins. Mol. Cell Biol. 17:1997;6459-6464.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 6459-6464
    • Pajovic, S.1    Wong, E.L.2    Black, A.R.3    Azizkhan, J.C.4
  • 137
    • 0028834302 scopus 로고
    • Isolation and characterization of a chicken homolog of the E2F-1 transcription factor
    • Pasteau S., Loiseau L., Arnaud L., Trembleau A., Brun G. Isolation and characterization of a chicken homolog of the E2F-1 transcription factor. Oncogene. 11:1995;1475-1486.
    • (1995) Oncogene , vol.11 , pp. 1475-1486
    • Pasteau, S.1    Loiseau, L.2    Arnaud, L.3    Trembleau, A.4    Brun, G.5
  • 138
    • 0030690423 scopus 로고    scopus 로고
    • Modular organization of the E2F1 activation domain and its interaction with general transcription factors TBP and TFIIH
    • Pearson A., Greenblatt J. Modular organization of the E2F1 activation domain and its interaction with general transcription factors TBP and TFIIH. Oncogene. 15:1997;2643-2658.
    • (1997) Oncogene , vol.15 , pp. 2643-2658
    • Pearson, A.1    Greenblatt, J.2
  • 139
    • 0028801689 scopus 로고
    • Phosphorylation of a specific cdk site in E2F-1 affects its electrophoretic mobility and promotes pRB-binding in vitro
    • Peeper D.S., Keblusek P., Helin K., Toebes M., van der Eb A.J., Zantema A. Phosphorylation of a specific cdk site in E2F-1 affects its electrophoretic mobility and promotes pRB-binding in vitro. Oncogene. 10:1995;39-48.
    • (1995) Oncogene , vol.10 , pp. 39-48
    • Peeper, D.S.1    Keblusek, P.2    Helin, K.3    Toebes, M.4    Van Der Eb, A.J.5    Zantema, A.6
  • 140
    • 0031306844 scopus 로고    scopus 로고
    • The regulation of cyclin-dependent kinase inhibitors (CKIs)
    • Peter M. The regulation of cyclin-dependent kinase inhibitors (CKIs). Progr. Cell Cycle Res. 3:1997;99-108.
    • (1997) Progr. Cell Cycle Res. , vol.3 , pp. 99-108
    • Peter, M.1
  • 141
    • 0030739355 scopus 로고    scopus 로고
    • Induction of DNA synthesis and apoptosis are separable functions of E2F-1
    • Phillips A.C., Bates S., Ryan K.M., Helin K., Vousden K.H. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev. 11:1997;1853-1863.
    • (1997) Genes Dev. , vol.11 , pp. 1853-1863
    • Phillips, A.C.1    Bates, S.2    Ryan, K.M.3    Helin, K.4    Vousden, K.H.5
  • 142
    • 0031850645 scopus 로고    scopus 로고
    • Differential activities of E2F family members: Unique functions in regulating transcription
    • Pierce A.M., Schneider-Broussard R., Philhower J.L., Johnson D.G. Differential activities of E2F family members: unique functions in regulating transcription. Mol. Carcinogen. 22:1998;190-198.
    • (1998) Mol. Carcinogen. , vol.22 , pp. 190-198
    • Pierce, A.M.1    Schneider-Broussard, R.2    Philhower, J.L.3    Johnson, D.G.4
  • 143
    • 0032992363 scopus 로고    scopus 로고
    • E2F-1 has properties of a radiosensitizer and its regulation by cyclin A kinase is required for cell survival of fibrosarcoma cells lacking p53
    • in process citation
    • Pruschy M., Wirbelauer C., Glanzmann C., Bodis S., Krek W. E2F-1 has properties of a radiosensitizer and its regulation by cyclin A kinase is required for cell survival of fibrosarcoma cells lacking p53. Cell Growth Differ. 10:1999;141-146. in process citation.
    • (1999) Cell Growth Differ. , vol.10 , pp. 141-146
    • Pruschy, M.1    Wirbelauer, C.2    Glanzmann, C.3    Bodis, S.4    Krek, W.5
  • 144
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin X.Q., Livingston D.M., Kaelin W.G. Jr., Adams P.D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA. 91:1994;10918-10922.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.Q.1    Livingston, D.M.2    Kaelin W.G., Jr.3    Adams, P.D.4
  • 146
    • 0029821229 scopus 로고    scopus 로고
    • DP-2, a heterodimeric partner of E2F - Identification and characterization of DP-2 proteins expressed in vivo
    • Rogers K.T., Higgins P.D.R., Milla M.M., Phillips R.S., Horowitz J.M. DP-2, a heterodimeric partner of E2F - identification and characterization of DP-2 proteins expressed in vivo. Proc. Natl. Acad. Sci. USA. 93:1996;7594-7599.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7594-7599
    • Rogers, K.T.1    Higgins, P.D.R.2    Milla, M.M.3    Phillips, R.S.4    Horowitz, J.M.5
  • 147
    • 0033083003 scopus 로고    scopus 로고
    • Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein
    • Ross J.F., Liu X., Dynlacht B.D. Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein. Mol. Cell. 3:1999;195-205.
    • (1999) Mol. Cell , vol.3 , pp. 195-205
    • Ross, J.F.1    Liu, X.2    Dynlacht, B.D.3
  • 149
    • 0032331371 scopus 로고    scopus 로고
    • Protein phosphatase type 1, the product of the retinoblastoma susceptibility gene, and cell cycle control
    • Rubin E., Tamrakar S., Ludlow J.W. Protein phosphatase type 1, the product of the retinoblastoma susceptibility gene, and cell cycle control. Front Biosci. 3:1998;D1209-D1919.
    • (1998) Front Biosci. , vol.3
    • Rubin, E.1    Tamrakar, S.2    Ludlow, J.W.3
  • 151
    • 0002673218 scopus 로고    scopus 로고
    • E2Fs and the retinoblastoma family
    • M. Yaniv, & J. Ghysdael. Basel, Switzerland: Birkhauser Verlag Cell Cycle Regulators and Chromosomal Translocation
    • Sardet C., LeCam L., Fabbrizio E., Vidal M. E2Fs and the retinoblastoma family. Yaniv M., Ghysdael J. Cell Cycle Regulators and Chromosomal Translocation. Oncogenes as Transcriptional Regulators. Vol. 2:1997;1-62 Birkhauser Verlag, Basel, Switzerland.
    • (1997) Oncogenes As Transcriptional Regulators , vol.2 , pp. 1-62
    • Sardet, C.1    Lecam, L.2    Fabbrizio, E.3    Vidal, M.4
  • 153
    • 0028142091 scopus 로고
    • Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ
    • Saxon M.L., Zhao X., Black J.D. Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ. J. Cell Biol. 126:1994;747-763.
    • (1994) J. Cell Biol. , vol.126 , pp. 747-763
    • Saxon, M.L.1    Zhao, X.2    Black, J.D.3
  • 154
    • 0030747725 scopus 로고    scopus 로고
    • Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals
    • Sears R., Ohtani K., Nevins J.R. Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals. Mol. Cell Biol. 17:1997;5227-5235.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 5227-5235
    • Sears, R.1    Ohtani, K.2    Nevins, J.R.3
  • 155
    • 0029612231 scopus 로고
    • A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites
    • Sellers W.R., Rodgers J.W., Kaelin W.G. Jr. A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc. Natl. Acad. Sci. USA. 92:1995;11544-11548.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11544-11548
    • Sellers, W.R.1    Rodgers, J.W.2    Kaelin W.G., Jr.3
  • 156
    • 0031930466 scopus 로고    scopus 로고
    • Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation and suppress tumor cell growth
    • Sellers W.R., Novitch B.G., Miyake S., Heith A., Otterson G.A., Kaye F.J., Lassar A.B., Kaelin W.G. Jr. Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation and suppress tumor cell growth. Genes Dev. 12:1998;95-106.
    • (1998) Genes Dev. , vol.12 , pp. 95-106
    • Sellers, W.R.1    Novitch, B.G.2    Miyake, S.3    Heith, A.4    Otterson, G.A.5    Kaye, F.J.6    Lassar, A.B.7    Kaelin W.G., Jr.8
  • 157
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan B., Lee W.H. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell Biol. 14:1994;8166-8173.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.H.2
  • 158
    • 0030069682 scopus 로고    scopus 로고
    • Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis
    • Shan B., Durfee T., Lee W.H. Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis. Proc. Natl. Acad. Sci. USA. 93:1996;679-684.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 679-684
    • Shan, B.1    Durfee, T.2    Lee, W.H.3
  • 159
    • 0029805888 scopus 로고    scopus 로고
    • The molecular basis of E2F-1/DP-1-induced S-phase entry and apoptosis
    • Shan B., Farmer A.A., Lee W.H. The molecular basis of E2F-1/DP-1-induced S-phase entry and apoptosis. Cell Growth Differ. 7:1996;689-697.
    • (1996) Cell Growth Differ. , vol.7 , pp. 689-697
    • Shan, B.1    Farmer, A.A.2    Lee, W.H.3
  • 160
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 161
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • Singh P., Wong S.H., Hong W. Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J. 13:1994;3329-3338.
    • (1994) EMBO J. , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 162
    • 0030782340 scopus 로고    scopus 로고
    • E2F transcription factor action, regulation and possible role in human cancer
    • Sladek T.L. E2F transcription factor action, regulation and possible role in human cancer. Cell Prolif. 30:1997;97-105.
    • (1997) Cell Prolif. , vol.30 , pp. 97-105
    • Sladek, T.L.1
  • 163
    • 0027403342 scopus 로고
    • A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter
    • Slansky J.E., Li Y., Kaelin W.G., Farnham P.J. A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter. Mol. Cell Biol. 13:1993;1610-1618.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 1610-1618
    • Slansky, J.E.1    Li, Y.2    Kaelin, W.G.3    Farnham, P.J.4
  • 165
    • 0031815206 scopus 로고    scopus 로고
    • Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth
    • Smith E.J., Leone G., Nevins J.R. Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth. Cell Growth Differ. 9:1998;297-303.
    • (1998) Cell Growth Differ. , vol.9 , pp. 297-303
    • Smith, E.J.1    Leone, G.2    Nevins, J.R.3
  • 166
    • 0032525913 scopus 로고    scopus 로고
    • Cell cycle regulation of the transcriptional coactivators p300 and CREB binding protein
    • Snowden A.W., Perkins N.D. Cell cycle regulation of the transcriptional coactivators p300 and CREB binding protein. Biochem. Pharmacol. 55:1998;1947-1954.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1947-1954
    • Snowden, A.W.1    Perkins, N.D.2
  • 167
    • 0030444208 scopus 로고    scopus 로고
    • Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E
    • Soferlevi Y., Resnitzky D. Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E. Oncogene. 13:1996;2431-2437.
    • (1996) Oncogene , vol.13 , pp. 2431-2437
    • Soferlevi, Y.1    Resnitzky, D.2
  • 170
    • 0029896193 scopus 로고    scopus 로고
    • Transcriptional repression and growth suppression by the p107 pocket protein
    • Starostik P., Chow K.N., Dean D.C. Transcriptional repression and growth suppression by the p107 pocket protein. Mol. Cell Biol. 16:1996;3606-3614.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 3606-3614
    • Starostik, P.1    Chow, K.N.2    Dean, D.C.3
  • 171
    • 0032533860 scopus 로고    scopus 로고
    • The COOH-terminal region of pRb2/p130 binds to histone deacetylase 1 (HDAC1), enhancing transcriptional repression of the E2F-dependent cyclin A promoter
    • Stiegler P., De Luca A., Bagella L., Giordano A. The COOH-terminal region of pRb2/p130 binds to histone deacetylase 1 (HDAC1), enhancing transcriptional repression of the E2F-dependent cyclin A promoter. Cancer Res. 58:1998;5049-5052.
    • (1998) Cancer Res. , vol.58 , pp. 5049-5052
    • Stiegler, P.1    De Luca, A.2    Bagella, L.3    Giordano, A.4
  • 174
    • 0031975921 scopus 로고    scopus 로고
    • E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation
    • Strom D.K., Cleveland J.L., Chellappan S., Nip J., Hiebert S.W. E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation. Cell Growth Differ. 9:1998;59-69.
    • (1998) Cell Growth Differ. , vol.9 , pp. 59-69
    • Strom, D.K.1    Cleveland, J.L.2    Chellappan, S.3    Nip, J.4    Hiebert, S.W.5
  • 175
    • 0032030770 scopus 로고    scopus 로고
    • Histone acetylation and transcriptional regulatory mechanisms
    • Struhl K. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12:1998;599-606.
    • (1998) Genes Dev. , vol.12 , pp. 599-606
    • Struhl, K.1
  • 176
    • 0032552031 scopus 로고    scopus 로고
    • A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer
    • Suzuki M., Okuyama S., Okamoto S., Shirasuna K., Nakajima T., Hachiya T., Nojima H., Sekiya S., Oda K. A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer. Oncogene. 17:1998;853-865.
    • (1998) Oncogene , vol.17 , pp. 853-865
    • Suzuki, M.1    Okuyama, S.2    Okamoto, S.3    Shirasuna, K.4    Nakajima, T.5    Hachiya, T.6    Nojima, H.7    Sekiya, S.8    Oda, K.9
  • 177
    • 0030688065 scopus 로고    scopus 로고
    • Subunit composition determines E2F DNA-binding site specificity
    • Tao Y., Kassatly R.F., Cress W.D., Horowitz J.M. Subunit composition determines E2F DNA-binding site specificity. Mol. Cell Biol. 17:1997;6994-7007.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 6994-7007
    • Tao, Y.1    Kassatly, R.F.2    Cress, W.D.3    Horowitz, J.M.4
  • 178
    • 0030033955 scopus 로고    scopus 로고
    • Expression of the E2F-1/DP-1 transcription factor in murine development
    • Tevosian S.G., Paulson K.E., Bronson R., Yee A.S. Expression of the E2F-1/DP-1 transcription factor in murine development. Cell Growth Differ. 7:1996;43-52.
    • (1996) Cell Growth Differ. , vol.7 , pp. 43-52
    • Tevosian, S.G.1    Paulson, K.E.2    Bronson, R.3    Yee, A.S.4
  • 180
    • 0031846920 scopus 로고    scopus 로고
    • An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro
    • Tomita N., Horiuchi M., Tomita S., Gibbons G.H., Kim J.Y., Baran D., Dzau V.J. An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro. Am. J. Physiol. 275:1998;F278-F284.
    • (1998) Am. J. Physiol. , vol.275
    • Tomita, N.1    Horiuchi, M.2    Tomita, S.3    Gibbons, G.H.4    Kim, J.Y.5    Baran, D.6    Dzau, V.J.7
  • 182
    • 0029997146 scopus 로고    scopus 로고
    • The CBP co-activator stimulates E2F1/DP1 activity
    • Trouche D., Cook A., Kouzarides T. The CBP co-activator stimulates E2F1/DP1 activity. Nucleic Acids Res. 24:1996;4139-4145.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4139-4145
    • Trouche, D.1    Cook, A.2    Kouzarides, T.3
  • 183
    • 0032159103 scopus 로고    scopus 로고
    • Mutation of E2F-1 suppresses apoptosis and inappropriate S-phase entry and extends survival of Rb-deficient mouse embryos
    • Tsai K.Y., Hu Y., Macleod K.F., Crowley D., Yamasaki L., Jacks T. Mutation of E2F-1 suppresses apoptosis and inappropriate S-phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell. 2:1998;293-304.
    • (1998) Mol. Cell , vol.2 , pp. 293-304
    • Tsai, K.Y.1    Hu, Y.2    Macleod, K.F.3    Crowley, D.4    Yamasaki, L.5    Jacks, T.6
  • 184
    • 0030793191 scopus 로고    scopus 로고
    • Vitamin E succinate inhibits proliferation of BT-20 human breast cancer cells: Increased binding of cyclin A negatively regulates E2F transactivation activity
    • Turley J.M., Ruscetti F.W., Kim S.J., Fu T., Gou F.V., Birchenall-Roberts M.C. Vitamin E succinate inhibits proliferation of BT-20 human breast cancer cells: increased binding of cyclin A negatively regulates E2F transactivation activity. Cancer Res. 57:1997;2668-2675.
    • (1997) Cancer Res. , vol.57 , pp. 2668-2675
    • Turley, J.M.1    Ruscetti, F.W.2    Kim, S.J.3    Fu, T.4    Gou, F.V.5    Birchenall-Roberts, M.C.6
  • 185
    • 0029000724 scopus 로고
    • Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: Superactivation by Rb requires amino acids necessary for growth suppression
    • Udvadia A.J., Templeton D.J., Horowitz J.M. Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. Proc. Natl. Acad. Sci. USA. 92:1995;3953-3957.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3953-3957
    • Udvadia, A.J.1    Templeton, D.J.2    Horowitz, J.M.3
  • 186
    • 0032567651 scopus 로고    scopus 로고
    • The molecular and functional characterization of E2F-5 transcription factor
    • Vaishnav Y.N., Vaishnav M.Y., Pant V. The molecular and functional characterization of E2F-5 transcription factor. Biochem. Biophys. Res. Commun. 242:1998;586-592.
    • (1998) Biochem. Biophys. Res. Commun. , vol.242 , pp. 586-592
    • Vaishnav, Y.N.1    Vaishnav, M.Y.2    Pant, V.3
  • 188
    • 0030789435 scopus 로고    scopus 로고
    • E2F-mediated growth regulation requires transcription factor cooperation
    • Van Ginkel P.R., Hsiao K.M., Schjerven H., Farnham P.J. E2F-mediated growth regulation requires transcription factor cooperation. J. Biol. Chem. 272:1996;18367-18374.
    • (1996) J. Biol. Chem. , vol.272 , pp. 18367-18374
    • Van Ginkel, P.R.1    Hsiao, K.M.2    Schjerven, H.3    Farnham, P.J.4
  • 190
    • 0030667320 scopus 로고    scopus 로고
    • E2F activity is regulated by cell cycle-dependent changes in subcellular localization
    • Verona R., Moberg K., Estes S., Starz M., Vernon J.P., Lees J.A. E2F activity is regulated by cell cycle-dependent changes in subcellular localization. Mol. Cell Biol. 17:1997;7268-7282.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 7268-7282
    • Verona, R.1    Moberg, K.2    Estes, S.3    Starz, M.4    Vernon, J.P.5    Lees, J.A.6
  • 191
    • 0029840668 scopus 로고    scopus 로고
    • Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system
    • Vidal M., Braun P., Chen E., Boeke J.D., Harlow E. Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system. Proc. Natl. Acad. Sci. USA. 93:1996;10321-10326.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10321-10326
    • Vidal, M.1    Braun, P.2    Chen, E.3    Boeke, J.D.4    Harlow, E.5
  • 192
    • 1842334436 scopus 로고    scopus 로고
    • Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein
    • Voit R., Schafer K., Grummt I. Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein. Mol. Cell Biol. 17:1997;4230-4237.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 4230-4237
    • Voit, R.1    Schafer, K.2    Grummt, I.3
  • 194
    • 0033559703 scopus 로고    scopus 로고
    • Regulation of Rb and E2F by signal transduction cascades: Divergent effects of JNK1 and p38 kinases
    • Wang S., Nath N., Minden A., Chellappan S. Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases. EMBO J. 18:1999;1559-1570.
    • (1999) EMBO J. , vol.18 , pp. 1559-1570
    • Wang, S.1    Nath, N.2    Minden, A.3    Chellappan, S.4
  • 195
    • 0026636908 scopus 로고
    • Retinoblastoma protein switches the E2F site from positive to negative element
    • Weintraub S.J., Prater C.A., Dean D.C. Retinoblastoma protein switches the E2F site from positive to negative element. Nature. 358:1992;259-261.
    • (1992) Nature , vol.358 , pp. 259-261
    • Weintraub, S.J.1    Prater, C.A.2    Dean, D.C.3
  • 196
    • 0029043782 scopus 로고
    • Mechanism of active transcriptional repression by the retinoblastoma protein
    • Weintraub S.J., Chow K.N., Luo R.X., Zhang S.H., He S., Dean D.C. Mechanism of active transcriptional repression by the retinoblastoma protein. Nature. 375:1995;812-815.
    • (1995) Nature , vol.375 , pp. 812-815
    • Weintraub, S.J.1    Chow, K.N.2    Luo, R.X.3    Zhang, S.H.4    He, S.5    Dean, D.C.6
  • 197
    • 0027429964 scopus 로고
    • A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-abl tyrosine kinase in the cell cycle
    • Welch P.J., Wang J.Y. A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-abl tyrosine kinase in the cell cycle. Cell. 75:1993;779-790.
    • (1993) Cell , vol.75 , pp. 779-790
    • Welch, P.J.1    Wang, J.Y.2
  • 198
    • 0031051550 scopus 로고    scopus 로고
    • Accumulation of E2F-4/DP-1 DNA binding complexes correlates with induction of DHFR gene expression during the G(1) to S-phase transition
    • Wells J.M., Illenye S., Magae J., Wu C.L., Heintz N.H. Accumulation of E2F-4/DP-1 DNA binding complexes correlates with induction of DHFR gene expression during the G(1) to S-phase transition. J. Biol. Chem. 272:1997;4483-4492.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4483-4492
    • Wells, J.M.1    Illenye, S.2    Magae, J.3    Wu, C.L.4    Heintz, N.H.5
  • 199
    • 0031052889 scopus 로고    scopus 로고
    • The predominant E2F complex in human primary haemopoietic cells and in AML blasts contains E2F-4, DP-1 and p130
    • Williams C.D., Linch D.C., Sorensen T.S., Lathangue N.B., Thomas N.S.B. The predominant E2F complex in human primary haemopoietic cells and in AML blasts contains E2F-4, DP-1 and p130. Br. J. Haematol. 96:1997;688-696.
    • (1997) Br. J. Haematol. , vol.96 , pp. 688-696
    • Williams, C.D.1    Linch, D.C.2    Sorensen, T.S.3    Lathangue, N.B.4    Thomas, N.S.B.5
  • 200
    • 1842413645 scopus 로고    scopus 로고
    • P130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity
    • Woo M.S.A., Sanchez I., Dynlacht B.D. p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity. Mol. Cell Biol. 17:1997;3566-3579.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 3566-3579
    • Woo, M.S.A.1    Sanchez, I.2    Dynlacht, B.D.3
  • 201
    • 0028222124 scopus 로고
    • P53 and E2F-1 cooperate to mediate apoptosis
    • Wu X., Levine A.J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA. 91:1994;3602-3606.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 204
    • 0028019279 scopus 로고
    • Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
    • Xu M., Sheppard K.A., Peng C.Y., Yee A.S., Piwnica-Worms H. Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol. Cell Biol. 14:1994;8420-8431.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 8420-8431
    • Xu, M.1    Sheppard, K.A.2    Peng, C.Y.3    Yee, A.S.4    Piwnica-Worms, H.5
  • 205
    • 0028945789 scopus 로고
    • Multiple members of the E2F transcription factor family are the products of oncogenes
    • Xu G.F., Livingston D.M., Krek W. Multiple members of the E2F transcription factor family are the products of oncogenes. Proc. Natl. Acad. Sci. USA. 92:1995;1357-1361.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1357-1361
    • Xu, G.F.1    Livingston, D.M.2    Krek, W.3
  • 207
    • 0031603542 scopus 로고    scopus 로고
    • Growth regulation by the E2F and DP transcription factor families
    • Yamasaki L. Growth regulation by the E2F and DP transcription factor families. Results Probl. Cell Differ. 22:1998;199-227.
    • (1998) Results Probl. Cell Differ. , vol.22 , pp. 199-227
    • Yamasaki, L.1
  • 208
    • 0031575755 scopus 로고    scopus 로고
    • Novel phosphorylated forms of E2F-1 transcription factor bind to the retinoblastoma protein in cells overexpressing an E2F-1 cDNA
    • Yang X.H., Sladek T.L. Novel phosphorylated forms of E2F-1 transcription factor bind to the retinoblastoma protein in cells overexpressing an E2F-1 cDNA. Biochem. Biophys. Res. Comm. 232:1997;336-339.
    • (1997) Biochem. Biophys. Res. Comm. , vol.232 , pp. 336-339
    • Yang, X.H.1    Sladek, T.L.2
  • 209
    • 0032496436 scopus 로고    scopus 로고
    • New perspectives on retinoblastoma family functions in differentiation
    • Yee A.S., Shih H.H., Tevosian S.G. New perspectives on retinoblastoma family functions in differentiation. Front Biosci. 3:1998;D532-D547.
    • (1998) Front Biosci. , vol.3
    • Yee, A.S.1    Shih, H.H.2    Tevosian, S.G.3
  • 210
    • 0029819994 scopus 로고    scopus 로고
    • PRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis
    • Zacksenhaus E., Jiang Z., Chung D., Marth J.D., Phillips R.A., Gallie B.L. pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev. 10:1996;3051-3064.
    • (1996) Genes Dev. , vol.10 , pp. 3051-3064
    • Zacksenhaus, E.1    Jiang, Z.2    Chung, D.3    Marth, J.D.4    Phillips, R.A.5    Gallie, B.L.6
  • 211
    • 0029066888 scopus 로고
    • Cloning and characterization of human DP2, a novel dimerization partner of E2F
    • Zhang Y., Chellappan S.P. Cloning and characterization of human DP2, a novel dimerization partner of E2F. Oncogene. 10:1995;2085-2093.
    • (1995) Oncogene , vol.10 , pp. 2085-2093
    • Zhang, Y.1    Chellappan, S.P.2
  • 212
    • 0033580279 scopus 로고    scopus 로고
    • The yeast cryptococcus neoformans uses 'mammalian' enhancer sites in the regulation of the virulence gene, CNLAC1
    • Zhang S., Varma A., Williamson P.R. The yeast cryptococcus neoformans uses 'mammalian' enhancer sites in the regulation of the virulence gene, CNLAC1. Gene. 227:1999;231-240.
    • (1999) Gene , vol.227 , pp. 231-240
    • Zhang, S.1    Varma, A.2    Williamson, P.R.3
  • 214
    • 0033559030 scopus 로고    scopus 로고
    • Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP
    • Zheng N., Fraenkel E., Pabo C.O., Pavletich N.P. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev. 13:1999;666-674.
    • (1999) Genes Dev. , vol.13 , pp. 666-674
    • Zheng, N.1    Fraenkel, E.2    Pabo, C.O.3    Pavletich, N.P.4
  • 215
    • 0029054133 scopus 로고
    • Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins
    • Zhu L.G., Zhu L.Y., Xie E.Z., Chang L.S. Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins. Mol. Cell Biol. 15:1995;3552-3562.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3552-3562
    • Zhu, L.G.1    Zhu, L.Y.2    Xie, E.Z.3    Chang, L.S.4
  • 216
    • 0029079936 scopus 로고
    • Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression
    • Zwicker J., Lucibello F.C., Wolfraim L.A., Gross C., Truss M., Engeland K., Muller R. Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression. EMBO J. 14:1995;4514-4522.
    • (1995) EMBO J. , vol.14 , pp. 4514-4522
    • Zwicker, J.1    Lucibello, F.C.2    Wolfraim, L.A.3    Gross, C.4    Truss, M.5    Engeland, K.6    Muller, R.7


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