메뉴 건너뛰기




Volumn 10, Issue 3, 1999, Pages 141-146

E2F-1 has properties of a radiosensitizer and its regulation by cyclin A kinase is required for cell survival of fibrosarcoma cells lacking p53

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; RADIOSENSITIZING AGENT; TRANSCRIPTION FACTOR E2F;

EID: 0032992363     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (29)

References (33)
  • 1
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family members
    • Dyson, N. The regulation of E2F by pRB-family members. Genes Dev., 12: 2245-2262, 1998.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 2
    • 0031886093 scopus 로고    scopus 로고
    • Regulation of cell proliferation by the E2F transcription factors
    • Helin, K. Regulation of cell proliferation by the E2F transcription factors. Curr. Opin. Genet. Dev., 8: 28-35, 1998.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 28-35
    • Helin, K.1
  • 3
    • 0029612231 scopus 로고
    • A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites
    • Sellers, W. R., Rodgers, J. W., and Kaelin, W. G. A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc. Natl. Acad. Sci. USA, 92: 11544-11548, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11544-11548
    • Sellers, W.R.1    Rodgers, J.W.2    Kaelin, W.G.3
  • 4
    • 0029043782 scopus 로고
    • Mechanism of active transcriptional repression by the retinoblastoma protein
    • Weintraub, S. J., Chow, K. N. B., Luo, R. X., Zhang, S. H., He, S., and Dean, S. C. Mechanism of active transcriptional repression by the retinoblastoma protein. Nature (Lond.), 375: 812-815, 1995.
    • (1995) Nature (Lond.) , vol.375 , pp. 812-815
    • Weintraub, S.J.1    Chow, K.N.B.2    Luo, R.X.3    Zhang, S.H.4    He, S.5    Dean, S.C.6
  • 5
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 6
    • 0028019279 scopus 로고
    • Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
    • Xu, M., Sheppard, K. A., Peng, C. Y., Yee, A. S., and Piwnica-Worms, H. Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol. Cell. Biol., 14: 8420-8431, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8420-8431
    • Xu, M.1    Sheppard, K.A.2    Peng, C.Y.3    Yee, A.S.4    Piwnica-Worms, H.5
  • 7
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek, W., Ewen, M. E., Shirodkar, S., Arany, Z., Kaelin, W. G., Jr., and Livingston, D. M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell, 78: 161-172, 1994.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin W.G., Jr.5    Livingston, D.M.6
  • 8
    • 0027936686 scopus 로고
    • Differential regulation of E2F transactivation by cyclin/cdk2 complexes
    • Dynlacht, B. D., Flores, O., Lees, J. A., and Harlow, E. Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev., 8: 1772-1786, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 1772-1786
    • Dynlacht, B.D.1    Flores, O.2    Lees, J.A.3    Harlow, E.4
  • 10
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • Singh, P., Wong, S., and Hong, W. Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J., 13: 3329-3338, 1994.
    • (1994) EMBO J. , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.2    Hong, W.3
  • 11
    • 0028945789 scopus 로고
    • Multiple members of the E2F transcription factor family are the products of oncogenes
    • Xu, G., Livingston, D. M., and Krek, W. Multiple members of the E2F transcription factor family are the products of oncogenes. Proc. Natl. Acad. Sci. USA, 92: 1357-1361, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1357-1361
    • Xu, G.1    Livingston, D.M.2    Krek, W.3
  • 13
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F-1 induced quiescent cells to enter S phase
    • Johnson, D. G., Schwarz, J. K., Cress, W. D., and Nevins, J. R. Expression of transcription factor E2F-1 induced quiescent cells to enter S phase. Nature (Lond.), 365: 349-352, 1993.
    • (1993) Nature (Lond.) , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 14
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S phase entry and p53-mediated apoptosis
    • Qin, X-Q., Livingston, D. M., Kaelin, W. G., and Adams, P. Deregulated transcription factor E2F-1 expression leads to S phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA, 91: 10918-10922, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin, W.G.3    Adams, P.4
  • 15
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S phase entry and leads to apoptosis
    • Shan, B. and Lee, W-H. Deregulated expression of E2F-1 induces S phase entry and leads to apoptosis. Mol. Cell. Biol., 14: 8166-8173, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.-H.2
  • 16
    • 0030738479 scopus 로고    scopus 로고
    • Distinct roles for E2F proteins in cell growth control and apoptosis
    • DeGregori, J. L. G., Miron, A., Jakoi, L., and Nevins, J. R. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc. Natl. Acad. Sci. USA, 94: 7245-7250, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7245-7250
    • DeGregori, J.L.G.1    Miron, A.2    Jakoi, L.3    Nevins, J.R.4
  • 17
    • 0032145569 scopus 로고    scopus 로고
    • Myc signaling via the arf tumor suppressor regulates p53-dependent apoptosis and immortalization
    • Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., and Roussel, M. F. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev., 12: 2424-2433, 1998.
    • (1998) Genes Dev. , vol.12 , pp. 2424-2433
    • Zindy, F.1    Eischen, C.M.2    Randle, D.H.3    Kamijo, T.4    Cleveland, J.L.5    Sherr, C.J.6    Roussel, M.F.7
  • 19
    • 0031992159 scopus 로고    scopus 로고
    • E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
    • Kowalik, T. F., DeGregori, J., Leone, G., Jakoi, L., and Nevins, J. R. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ., 9: 113-118, 1998.
    • (1998) Cell Growth Differ. , vol.9 , pp. 113-118
    • Kowalik, T.F.1    DeGregori, J.2    Leone, G.3    Jakoi, L.4    Nevins, J.R.5
  • 20
    • 0028960617 scopus 로고
    • E2F-1 overexpression in quiescent fibroblasts leads to induction of DNA synthesis and apoptosis
    • Kowalik, T. F., DeGregori, J., Schwarz, J. K., and Nevins, J. R. E2F-1 overexpression in quiescent fibroblasts leads to induction of DNA synthesis and apoptosis. J. Virol., 69: 2491-2500, 1995.
    • (1995) J. Virol. , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    DeGregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 21
    • 0028222124 scopus 로고
    • P53 and E2F-1 cooperate to mediate apoptosis
    • Wu, X., and Levine, A. J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA, 91: 3602-3606, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 22
    • 0030739355 scopus 로고    scopus 로고
    • Induction of DNA synthesis and apoptosis are separable functions of E2F-1
    • Phillips, A. C., Bates, S., Ryan, K. M., Helin, K., and Vousden, K. H. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev., 11: 1853-1863, 1997.
    • (1997) Genes Dev. , vol.11 , pp. 1853-1863
    • Phillips, A.C.1    Bates, S.2    Ryan, K.M.3    Helin, K.4    Vousden, K.H.5
  • 23
    • 0031024991 scopus 로고    scopus 로고
    • E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis
    • Nip, J., Strom, D. K., Fee, B. E., Zambetti, G., Cleveland, J., and Hiebert, S. W. E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis. Mol. Cell. Biol., 17: 1049-1056, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1049-1056
    • Nip, J.1    Strom, D.K.2    Fee, B.E.3    Zambetti, G.4    Cleveland, J.5    Hiebert, S.W.6
  • 24
    • 0030850752 scopus 로고    scopus 로고
    • E2F-1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
    • Hsieh, J-K., Fredersdorf, S., Kouzarides, T., Martin, K., and Lu, X. E2F-1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev., 11: 1840-1852, 1997.
    • (1997) Genes Dev. , vol.11 , pp. 1840-1852
    • Hsieh, J.-K.1    Fredersdorf, S.2    Kouzarides, T.3    Martin, K.4    Lu, X.5
  • 25
    • 0029559027 scopus 로고
    • Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint
    • Krek, W., Xu, G., and Livingston, D. M. Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell, 83: 1149-1158, 1995.
    • (1995) Cell , vol.83 , pp. 1149-1158
    • Krek, W.1    Xu, G.2    Livingston, D.M.3
  • 26
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine, A. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell, 88 , pp. 323-331
    • Levine, A.1
  • 27
    • 0027451668 scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S. L., Ruley, H. E., Jacks, T., and Housman, D. E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74: 957-976, 1993.
    • (1993) Cell , vol.74 , pp. 957-976
    • Lowe, S.L.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 29
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • Fisher, D. E. Apoptosis in cancer therapy: crossing the threshold. Cell, 78: 539-542, 1994.
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 30
    • 0030726461 scopus 로고    scopus 로고
    • Selective induction of p53 and chemosensitivity in rb-deficient calls by e1a mutants unable to bind the rb-related proteins
    • Samuelson, A. V., and Lowe, S. W. Selective induction of p53 and chemosensitivity in RB-deficient calls by E1A mutants unable to bind the RB-related proteins. Proc. Natl. Acad. Sci. USA, 94: 12094-12099, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12094-12099
    • Samuelson, A.V.1    Lowe, S.W.2
  • 31
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear, W. S., Nolen, G. P., Scott, M. L., and Baltimore, D. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA, 90: 8392-8396, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolen, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 32
    • 0027769885 scopus 로고
    • Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
    • Washington DC
    • Krek, W., Livingston, D. M., and Shirodkar, S. Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science (Washington DC), 262: 1557-1560, 1993.
    • (1993) Science , vol.262 , pp. 1557-1560
    • Krek, W.1    Livingston, D.M.2    Shirodkar, S.3
  • 33
    • 0032518828 scopus 로고    scopus 로고
    • Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45SKP2: Evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway
    • Lisztwan, J., Marti, A., Sutterluety, H., Gstaiger, M., Wirbelauer, C., and Krek, W. Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45SKP2: evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway. EMBO J., 17: 368-383, 1998.
    • (1998) EMBO J. , vol.17 , pp. 368-383
    • Lisztwan, J.1    Marti, A.2    Sutterluety, H.3    Gstaiger, M.4    Wirbelauer, C.5    Krek, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.