메뉴 건너뛰기




Volumn 5, Issue 3, 1998, Pages 585-589

Differential transcriptional activation by the N-terminal region of BRCA1 splice variants BRCA1a and BRCA1b

Author keywords

BRCA1a; BRCA1b; Breast cancer; Transcriptional activation; Zinc finger

Indexed keywords

BRCA1 PROTEIN; BRCA1A PROTEIN; BRCA1B PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 0031958724     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.5.3.585     Document Type: Article
Times cited : (20)

References (40)
  • 4
    • 0027960790 scopus 로고
    • Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds
    • Neuhausen SL and Marshall CJ: Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds. Cancer Res 54: 6069-6072, 1994.
    • (1994) Cancer Res , vol.54 , pp. 6069-6072
    • Neuhausen, S.L.1    Marshall, C.J.2
  • 5
    • 0026935108 scopus 로고
    • Allele losses in the region 17q 12-21 in familial breast and ovarian cancer involve the wild-type chromosome
    • Smith SA, Hasten DF, Evans DG and Ponder BA: Allele losses in the region 17q 12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nat Genet 2: 128-131, 1992.
    • (1992) Nat Genet , vol.2 , pp. 128-131
    • Smith, S.A.1    Hasten, D.F.2    Evans, D.G.3    Ponder, B.A.4
  • 7
    • 0029830051 scopus 로고    scopus 로고
    • Transcriptional activation by BRCA1
    • Chapman MS and Verma IM: Transcriptional activation by BRCA1. Nature 382: 678-679, 1996.
    • (1996) Nature , vol.382 , pp. 678-679
    • Chapman, M.S.1    Verma, I.M.2
  • 8
    • 0030474170 scopus 로고    scopus 로고
    • Evidence for a transcriptional activation function of BRCA1 C-terminal region
    • Monteiro AN, August A and Hanafusa H: Evidence for a transcriptional activation function of BRCA1 C-terminal region Proc Natl Acad Sci USA 93: 13595-13599, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13595-13599
    • Monteiro, A.N.1    August, A.2    Hanafusa, H.3
  • 10
    • 0028828673 scopus 로고
    • Expression of BRCA1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice
    • Lane TF, Deng C, Elson A, Lyu MS, Kozak CA and Leder P: Expression of BRCA1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. Genes Dev 9: 2712-2722, 1995.
    • (1995) Genes Dev , vol.9 , pp. 2712-2722
    • Lane, T.F.1    Deng, C.2    Elson, A.3    Lyu, M.S.4    Kozak, C.A.5    Leder, P.6
  • 12
    • 0028848589 scopus 로고
    • Mouse BRCA1: Localization sequence analysis and identification of evolutionary conserved domains
    • Abel KJ, Xu J, Yin G-Y, Lyons RH, Meisler MH and Weber BL: Mouse BRCA1: localization sequence analysis and identification of evolutionary conserved domains. Hum Mol Genet 4: 2265-2273, 1995.
    • (1995) Hum Mol Genet , vol.4 , pp. 2265-2273
    • Abel, K.J.1    Xu, J.2    Yin, G.-Y.3    Lyons, R.H.4    Meisler, M.H.5    Weber, B.L.6
  • 13
    • 0028880054 scopus 로고
    • Murine BRCA1: Sequence and significance for human missense mutations
    • Sharan SK, Wims M and Bradley A: Murine BRCA1: sequence and significance for human missense mutations. Hum Mol Genet 4: 2275-2278, 1995.
    • (1995) Hum Mol Genet , vol.4 , pp. 2275-2278
    • Sharan, S.K.1    Wims, M.2    Bradley, A.3
  • 14
    • 0030051903 scopus 로고    scopus 로고
    • BRCA1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities
    • Gowen LC, Johnson BL, Latour AM, Sulik KK and Koller BH: BRCA1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nat Genet 12: 191-194, 1996.
    • (1996) Nat Genet , vol.12 , pp. 191-194
    • Gowen, L.C.1    Johnson, B.L.2    Latour, A.M.3    Sulik, K.K.4    Koller, B.H.5
  • 15
    • 15844371372 scopus 로고    scopus 로고
    • The tumor suppressor gene BRCA1 is required for embryonic cellular proliferation in the mouse
    • Hakem R, de la Pomba JL, Sirard C, Mo R, Woo M. et al: The tumor suppressor gene BRCA1 is required for embryonic cellular proliferation in the mouse. Cell 85: 1009-1023, 1996.
    • (1996) Cell , vol.85 , pp. 1009-1023
    • Hakem, R.1    De la Pomba, J.L.2    Sirard, C.3    Mo, R.4    Woo, M.5
  • 16
    • 0029784528 scopus 로고    scopus 로고
    • Inactivation of the mouse BRCA1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development
    • Liu CY, Flesken-Nikitin A, Li S, Zeng Y and Lee WH: Inactivation of the mouse BRCA1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development. Genes Dev 10. 1835-1843, 1996.
    • (1996) Genes Dev , vol.10 , pp. 1835-1843
    • Liu, C.Y.1    Flesken-Nikitin, A.2    Li, S.3    Zeng, Y.4    Lee, W.H.5
  • 18
    • 0030059385 scopus 로고    scopus 로고
    • Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts
    • Rao VN, Shao N, Ahmad M and Reddy ESP: Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts. Oncogene 12: 523-528, 1996.
    • (1996) Oncogene , vol.12 , pp. 523-528
    • Rao, V.N.1    Shao, N.2    Ahmad, M.3    Reddy, E.S.P.4
  • 20
    • 0030838793 scopus 로고    scopus 로고
    • BRCA1 proteins are transported to the nucleus in the-absence of serum and splice variants BRCAla, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases
    • Wang H, Shao N, Ding QM, Cui JQ, Reddy ESP and Rao VN: BRCA1 proteins are transported to the nucleus in the-absence of serum and splice variants BRCAla, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases. Oncogene 15: 143-157, 1997.
    • (1997) Oncogene , vol.15 , pp. 143-157
    • Wang, H.1    Shao, N.2    Ding, Q.M.3    Cui, J.Q.4    Reddy, E.S.P.5    Rao, V.N.6
  • 22
    • 0029987651 scopus 로고    scopus 로고
    • BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner
    • Chen Y, Farmer AA, Chen CF, Jones DC, Chen PL and Lee WH: BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner. Cancer Res 56: 3168-3172, 1996.
    • (1996) Cancer Res , vol.56 , pp. 3168-3172
    • Chen, Y.1    Farmer, A.A.2    Chen, C.F.3    Jones, D.C.4    Chen, P.L.5    Lee, W.H.6
  • 23
    • 0031472370 scopus 로고    scopus 로고
    • Association of BRCA1 with Rad51 in mitotic and meiotic cells
    • Scully R, Chen J, Plug A, Xiao Y, Weaver D, et al: Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 88: 265-275, 1997.
    • (1997) Cell , vol.88 , pp. 265-275
    • Scully, R.1    Chen, J.2    Plug, A.3    Xiao, Y.4    Weaver, D.5
  • 25
    • 0030850047 scopus 로고    scopus 로고
    • Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
    • Scully R, Chen J, Ochs RL, Keegan K, Hoekstra M, Feunteun J, and Livingston DM: Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 90: 425-435, 1997.
    • (1997) Cell , vol.90 , pp. 425-435
    • Scully, R.1    Chen, J.2    Ochs, R.L.3    Keegan, K.4    Hoekstra, M.5    Feunteun, J.6    Livingston, D.M.7
  • 27
    • 0028950999 scopus 로고
    • Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression
    • Thompson ME, Jensen RA, Obermiller PS, Page DL and Holt JT: Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat Genet 9: 444-450, 1995.
    • (1995) Nat Genet , vol.9 , pp. 444-450
    • Thompson, M.E.1    Jensen, R.A.2    Obermiller, P.S.3    Page, D.L.4    Holt, J.T.5
  • 28
    • 0029948779 scopus 로고    scopus 로고
    • Induction of apoptosis by the tumor suppressor protein BRCA1
    • Shao N, Chai YL, Reddy ES and Rao VN: Induction of apoptosis by the tumor suppressor protein BRCA1. Oncosene 13: 1-7, 1996.
    • (1996) Oncosene , vol.13 , pp. 1-7
    • Shao, N.1    Chai, Y.L.2    Reddy, E.S.3    Rao, V.N.4
  • 31
    • 0024299083 scopus 로고
    • The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator
    • Webster N, Jin JR, Green S, Hollis M and Chambon P: The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator. Cell 52: 169-178, 1988.
    • (1988) Cell , vol.52 , pp. 169-178
    • Webster, N.1    Jin, J.R.2    Green, S.3    Hollis, M.4    Chambon, P.5
  • 32
    • 0024536716 scopus 로고
    • Elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints
    • Rao VN, Huebner K, Isobe M, Al-Rushdi A. Croce CM and Reddy ESP: Elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints. Science 244: 66-70, 1989.
    • (1989) Science , vol.244 , pp. 66-70
    • Rao, V.N.1    Huebner, K.2    Isobe, M.3    Al-Rushdi, A.4    Croce, C.M.5    Reddy, E.S.P.6
  • 33
    • 0027393914 scopus 로고
    • Delta elk-1, a variant of elk-1, fails to interact with the serum response factor and binds to DNA with modulated specificity
    • Rao VN and Reddy ESP: Delta elk-1, a variant of elk-1, fails to interact with the serum response factor and binds to DNA with modulated specificity. Cancer Res 53: 215-220, 1993.
    • (1993) Cancer Res , vol.53 , pp. 215-220
    • Rao, V.N.1    Reddy, E.S.P.2
  • 34
    • 0027297647 scopus 로고
    • The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
    • Marias R, Wynne and Treisman R: The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73: 381-393, 1993.
    • (1993) Cell , vol.73 , pp. 381-393
    • Marias, R.1    Wynne2    Treisman, R.3
  • 35
    • 0027428026 scopus 로고
    • Transcriptional activation domains of elk-1, delta elk-1 and SAP-1 proteins
    • Bhattacharya G, Lee L, Reddy ESP and Rao VN: Transcriptional activation domains of elk-1, delta elk-1 and SAP-1 proteins. Oncogene 8: 3459-3464, 1993.
    • (1993) Oncogene , vol.8 , pp. 3459-3464
    • Bhattacharya, G.1    Lee, L.2    Reddy, E.S.P.3    Rao, V.N.4
  • 37
    • 0026728801 scopus 로고
    • Non-dissociation of GAL4 and GAL80 in vivo after galactose induction
    • Leuther KK and Johnston SA: Non-dissociation of GAL4 and GAL80 in vivo after galactose induction. Science 256: 1333-1335, 1992.
    • (1992) Science , vol.256 , pp. 1333-1335
    • Leuther, K.K.1    Johnston, S.A.2
  • 38
    • 0023643078 scopus 로고
    • The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80
    • Ma J and Ptashne M: The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80. Cell 50: 137-142, 1987.
    • (1987) Cell , vol.50 , pp. 137-142
    • Ma, J.1    Ptashne, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.