-
1
-
-
0027497372
-
The retinoblastoma protein as a transcriptional repressor
-
Helin, K., and Harlow, E. The retinoblastoma protein as a transcriptional repressor. Trends Cell Biol., 3: 43-46, 1993.
-
(1993)
Trends Cell Biol.
, vol.3
, pp. 43-46
-
-
Helin, K.1
Harlow, E.2
-
2
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
Washington DC
-
Nevins, J. R. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (Washington DC), 258: 424-429, 1992.
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.R.1
-
3
-
-
0028267869
-
DRTF1/E2F: An expanding family of heterodimeric transcription factors implicated in cell-cycle control
-
La Thangue, N. B. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem. Sci., 19: 108-114, 1994.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 108-114
-
-
La Thangue, N.B.1
-
4
-
-
0029849620
-
Cancer cell cycles
-
Washington DC
-
Sherr, C. J. Cancer cell cycles. Science (Washington DC), 274: 1672-1677, 1996.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
5
-
-
0030933277
-
Oncoprotein networks
-
Hunter, T. Oncoprotein networks. Cell, 88: 333-346, 1997.
-
(1997)
Cell
, vol.88
, pp. 333-346
-
-
Hunter, T.1
-
6
-
-
0027491775
-
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
-
Johnson, D. G., Schwarz, J. K., Cress, W. D., and Nevins, J. R. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (Lond.), 365: 349-352, 1993.
-
(1993)
Nature (Lond.)
, vol.365
, pp. 349-352
-
-
Johnson, D.G.1
Schwarz, J.K.2
Cress, W.D.3
Nevins, J.R.4
-
7
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
Qin, X-Q., Livingston, D. M., Kaelin, W. G., and Adams, P. D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA. 91: 10918-10922, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.-Q.1
Livingston, D.M.2
Kaelin, W.G.3
Adams, P.D.4
-
8
-
-
0028360766
-
Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
-
Singh, P., Wong, S. W., and Hong, W. Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J., 13: 3329-3338, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 3329-3338
-
-
Singh, P.1
Wong, S.W.2
Hong, W.3
-
9
-
-
0028577731
-
Oncogenic capacity of the E2F1 gene
-
Johnson, D. G., Cress, W. D., Jakoi, L., and Nevins, J. R. Oncogenic capacity of the E2F1 gene. Proc. Natl. Acad. Sci. USA, 91: 12823-12827, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12823-12827
-
-
Johnson, D.G.1
Cress, W.D.2
Jakoi, L.3
Nevins, J.R.4
-
10
-
-
0028960617
-
E2F1 Overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
-
Kowalik, T. F., DeGregori, J., Schwarz, J. K., and Nevins, J. R. E2F1 Overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol., 69: 2491-2500, 1995.
-
(1995)
J. Virol.
, vol.69
, pp. 2491-2500
-
-
Kowalik, T.F.1
DeGregori, J.2
Schwarz, J.K.3
Nevins, J.R.4
-
11
-
-
0028222124
-
p53 and E2F-1 cooperate to mediate apoptosis
-
Wu, X., and Levine, A. J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA, 91: 3602-3606, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3602-3606
-
-
Wu, X.1
Levine, A.J.2
-
12
-
-
0028061670
-
Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
-
Shan, B., and Lee, W-H. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol., 14: 8166-8173, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8166-8173
-
-
Shan, B.1
Lee, W.-H.2
-
13
-
-
0030738479
-
Distinct roles for E2F proteins in cell growth control and apoptosis
-
DeGregori, J., Leone, G., Miron, A., Jakoi, L., and Nevins, J. R. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc. Natl. Acad. Sci. USA, 94: 7245-7250, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7245-7250
-
-
DeGregori, J.1
Leone, G.2
Miron, A.3
Jakoi, L.4
Nevins, J.R.5
-
14
-
-
0028860556
-
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis
-
Hiebert, S. W., Packham, G., Strom, D. K., Haffner, R., Oren, M., Zambetti, G., and Cleveland, J. L. E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis. Mol. Cell. Biol., 15: 6864-6874, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6864-6874
-
-
Hiebert, S.W.1
Packham, G.2
Strom, D.K.3
Haffner, R.4
Oren, M.5
Zambetti, G.6
Cleveland, J.L.7
-
15
-
-
0027262606
-
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis
-
Lowe, S. W., and Ruley, H. E. Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev., 7: 535-545, 1993.
-
(1993)
Genes Dev.
, vol.7
, pp. 535-545
-
-
Lowe, S.W.1
Ruley, H.E.2
-
16
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field, S. J., Tsai, F-Y., Kuo, F., Zubiaga, A. M., Kaelin, W. G., Jr., Livingston, D. M., Orkin, S. H., and Greenberg, M. E. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell, 85: 549-561, 1996.
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.-Y.2
Kuo, F.3
Zubiaga, A.M.4
Kaelin Jr., W.G.5
Livingston, D.M.6
Orkin, S.H.7
Greenberg, M.E.8
-
17
-
-
0030739355
-
Induction of DNA synthesis and apoptosis are separable functions of E2F-1
-
Phillips, A. C., Bates, S., Ryan, K. M., Helin, K., and Vousden, K. H. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev., 11: 1853-1863, 1997.
-
(1997)
Genes Dev.
, vol.11
, pp. 1853-1863
-
-
Phillips, A.C.1
Bates, S.2
Ryan, K.M.3
Helin, K.4
Vousden, K.H.5
-
18
-
-
0030850752
-
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
-
Hsieh, J-K., Fredersdorf, S., Kouzarides, T., Martin, K., and Lu, X. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev., 11: 1840-1852, 1997.
-
(1997)
Genes Dev.
, vol.11
, pp. 1840-1852
-
-
Hsieh, J.-K.1
Fredersdorf, S.2
Kouzarides, T.3
Martin, K.4
Lu, X.5
-
19
-
-
0028938734
-
p53-dependent growth arrest of REF52 cells containing newly amplified DNA
-
Ishizaka, Y., Chernov, M. V., Burns, C. M., and Stark, G. R. p53-dependent growth arrest of REF52 cells containing newly amplified DNA. Proc. Natl. Acad. Sci. USA, 92: 3224-3228, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3224-3228
-
-
Ishizaka, Y.1
Chernov, M.V.2
Burns, C.M.3
Stark, G.R.4
-
20
-
-
0025969355
-
Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest
-
Hicks, G. G., Egan, S. E., Greenberg, A. H., and Mowat, M. Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest. Mol. Cell. Biol., 11: 1344-1352, 1991.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1344-1352
-
-
Hicks, G.G.1
Egan, S.E.2
Greenberg, A.H.3
Mowat, M.4
-
21
-
-
0013568829
-
Regulation of transcription functions of the p53 tumour suppressor by the mdm-2 oncogene
-
Chen, J. D., Lin, J. Y., and Levine, A. J. Regulation of transcription functions of the p53 tumour suppressor by the mdm-2 oncogene. Mol. Med., 1: 141-152, 1995.
-
(1995)
Mol. Med.
, vol.1
, pp. 141-152
-
-
Chen, J.D.1
Lin, J.Y.2
Levine, A.J.3
-
22
-
-
0029913730
-
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
-
Chen, J., Wu, X., Lin, J., and Levine, A. J. mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol. Cell. Biol., 16: 2445-2452, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2445-2452
-
-
Chen, J.1
Wu, X.2
Lin, J.3
Levine, A.J.4
-
23
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones, S. N., Roe, A. E., Donehower, L. A., and Bradley, A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature (Lond.), 378: 206-208, 1995.
-
(1995)
Nature (Lond.)
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
24
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes de Oca Luna, R., Wagner, D. S., and Lozano, G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature (Lond.), 378: 203-206, 1995.
-
(1995)
Nature (Lond.)
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
25
-
-
0030046508
-
Life, death, and the pursuit of apoptosis
-
White, E. Life, death, and the pursuit of apoptosis. Genes Dev., 10: 1-15, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 1-15
-
-
White, E.1
-
26
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M. H. G., Jones, S. N., and Vousden, K. H. Regulation of p53 stability by Mdm2. Nature (Lond.), 387: 299-302, 1997.
-
(1997)
Nature (Lond.)
, vol.387
, pp. 299-302
-
-
Kubbutat, M.H.G.1
Jones, S.N.2
Vousden, K.H.3
-
27
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., Maya, R., Kazaz, A., and Oren, M. Mdm2 promotes the rapid degradation of p53. Nature (Lond.), 387: 296-299, 1997.
-
(1997)
Nature (Lond.)
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
28
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
Scheffner, M., Huibregtse, J. M., Vierstra, R. D., and Howley, P. M. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell, 75: 495-505, 1993.
-
(1993)
Cell
, vol.75
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
29
-
-
0029615315
-
Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1
-
O'Connor, D. J., Lam, E. W. F., Griffin, S., Zhong, S., Leighton, L. C., Burbidge, S. A., and Lu, X. Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1. EMBO J. 14: 6184-6192, 1995.
-
(1995)
EMBO J.
, vol.14
, pp. 6184-6192
-
-
O'Connor, D.J.1
Lam, E.W.F.2
Griffin, S.3
Zhong, S.4
Leighton, L.C.5
Burbidge, S.A.6
Lu, X.7
-
30
-
-
0029028353
-
Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein
-
Martin, K., Trouche, D., Hagemeier, C., Sorensen, T. S., La Thangue, N. B., and Kouzarides, T. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature (Lond.), 375: 691-694, 1995.
-
(1995)
Nature (Lond.)
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Sorensen, T.S.4
La Thangue, N.B.5
Kouzarides, T.6
-
31
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks, T., Fazeli, A., Schmitt, E. M., Bronson, R. T., Goodell, M. A., and Weinberg, R. A. Effects of an Rb mutation in the mouse. Nature (Lond.), 359: 295-300, 1992.
-
(1992)
Nature (Lond.)
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
32
-
-
0026744563
-
Mice deficient for Rb are nonviable and show detects in neurogenesis and haematopoiesis
-
Lee, E. Y. H. P., Chang, C-Y., Hu, N., Wang, Y-C. J., Lai, C-C., Herrup, K., Lee, W-H., and Bradley, A. Mice deficient for Rb are nonviable and show detects in neurogenesis and haematopoiesis. Nature (Lond.), 359: 288-294, 1992.
-
(1992)
Nature (Lond.)
, vol.359
, pp. 288-294
-
-
Lee, E.Y.H.P.1
Chang, C.-Y.2
Hu, N.3
Wang, Y.-C.J.4
Lai, C.-C.5
Herrup, K.6
Lee, W.-H.7
Bradley, A.8
-
33
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke, A. R., Maandag, E. R., van Roon, M., van der Lugt, N. M. T., van der Valk, M., Hooper, M. L., Berns, A., and te Riele, H. Requirement for a functional Rb-1 gene in murine development. Nature (Lond.), 359: 328-333, 1992.
-
(1992)
Nature (Lond.)
, vol.359
, pp. 328-333
-
-
Clarke, A.R.1
Maandag, E.R.2
Van Roon, M.3
Van Der Lugt, N.M.T.4
Van Der Valk, M.5
Hooper, M.L.6
Berns, A.7
Te Riele, H.8
-
34
-
-
0029819994
-
PRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis
-
Zacksenhaus, E., Jiang, Z., Chung, D., Marth, J. D., Phillips, R. A., and Gallie, B. L. pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev., 10: 3051-3064, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 3051-3064
-
-
Zacksenhaus, E.1
Jiang, Z.2
Chung, D.3
Marth, J.D.4
Phillips, R.A.5
Gallie, B.L.6
-
35
-
-
0027934570
-
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
-
Morgenbessen, S. D., Williams, B. O., Jacks, T., and DePincho, R. A. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature (Lond.), 371: 72-74, 1994.
-
(1994)
Nature (Lond.)
, vol.371
, pp. 72-74
-
-
Morgenbessen, S.D.1
Williams, B.O.2
Jacks, T.3
DePincho, R.A.4
-
36
-
-
0028873133
-
Expression of the E2F1 transcription factor overcomes type β transforming growth factor-mediated growth suppression
-
Schwarz, J. K., Bassing, C. H., Kovesdi, I., Datto, M. B., Blazing, M., George, S., Wang, X-F., and Nevins, J. R. Expression of the E2F1 transcription factor overcomes type β transforming growth factor-mediated growth suppression. Proc. Natl. Acad. Sci. USA, 92: 483-487, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 483-487
-
-
Schwarz, J.K.1
Bassing, C.H.2
Kovesdi, I.3
Datto, M.B.4
Blazing, M.5
George, S.6
Wang, X.-F.7
Nevins, J.R.8
-
37
-
-
0030755431
-
Functional analysis of E2F
-
Nevins, J. R., DeGregori, J., Jakoi, L., and Leone, G. Functional analysis of E2F. Methods Enzymol., 283: 205-219, 1997.
-
(1997)
Methods Enzymol.
, vol.283
, pp. 205-219
-
-
Nevins, J.R.1
DeGregori, J.2
Jakoi, L.3
Leone, G.4
-
39
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L., and Vogelstein, B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature (Lond.), 358: 80-83, 1992.
-
(1992)
Nature (Lond.)
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
40
-
-
0027367144
-
Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F
-
Ivey-Hoyle, M., Conroy, R., Huber, H. E., Goodhart, P. J., Oliff, A., and Heimbrook, D. C. Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol. Cell. Biol., 13: 7802-7812, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7802-7812
-
-
Ivey-Hoyle, M.1
Conroy, R.2
Huber, H.E.3
Goodhart, P.J.4
Oliff, A.5
Heimbrook, D.C.6
-
41
-
-
0029868367
-
A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation
-
Ikeda, M-A., Jakoi, L., and Nevins, J. R. A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc. Natl. Acad. Sci. USA, 93: 3215-3220, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3215-3220
-
-
Ikeda, M.-A.1
Jakoi, L.2
Nevins, J.R.3
|