Expression patterns of the E2F family of transcription factors during murine epithelial development

Cell Growth and Differentiation

Volumn 8, Issue 5, 1997, Pages 553-563

  Dagnino, L ^a,d   Fry, C J ^c   Bartley, S M ^c   Farnham, P ^c   Gallie, B L ^a,b   Phillips, R A ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR E2F;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; EPITHELIUM; GROWTH REGULATION; MOUSE; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F2 TRANSCRIPTION FACTOR; E2F4 TRANSCRIPTION FACTOR; E2F5 TRANSCRIPTION FACTOR; EMBRYONIC AND FETAL DEVELOPMENT; EPITHELIUM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PREGNANCY; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS;

ANIMALIA; MURINAE; VERTEBRATA;

EID: 0030991285     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Nevins, J. R. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (Washington DC), 258: 424-429, 1992.
2. Helin, K., and Harlow, E. The retinoblastoma protein as a transcriptional repressor. Trends Cell Biol., 3: 43-46, 1993.
3. La Thangue, N. B. DTRF1/E2F: an extending family of heterodimeric factors implicated in cell cycle control. Trends Biochem. Sci., 19: 108-114, 1994.
4. Helin, K., Lees, J. A., Vidal, M., Dyson, N., Harlow, E., and Fattaey, A. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell, 70: 337-350, 1992.
5. Ivey-Hoyle, M., Conroy, R., Huber, H. E., Goodhart, P. J., Oliff, A., and Heimbrook, D. C. Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol. Cell. Biol., 13: 7802-7812, 1993.
6. Kaelin, W., Jr., Krek, W., Sellers, W. R., DeCaprio, J. A., Ajchenbaum, F., Fuchs, C. S., Chittenden, T., Li, Y., Farnham, P. J., and Blanar, M. A. Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell, 70: 351-364, 1992.
7. Shan, B., Zhu, X., Chen, P. L., Durfee, T., Yang, Y., Sharp, D., and Lee, W. H. Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol. Cell. Biol., 12: 5620-5631, 1992.
8. Girling, R., Partridge, J. F., Bandara, L. R., Burden, N., Totty, N. F., Hsuan, J. J., and La Thangue, N. B. A new component of the transcription factor DRTF1/E2F. Nature (Lond.), 362: 83-87, 1993.
9. Lees, J. A., Saito, M., Vidai, M., Valentine, M., Look, T., Harlow, E., Dyson, N., and Helin, K. The retinoblastoma protein binds to a family of E2F transcription factors. Mol. Cell. Biol., 13: 7813-7825, 1993.
10. Beijersbergen, R. L., Kerkhoven, R. M., Zhu, L., Carlee, L., Voorhoeve, P. M., and Bernards, R. E2F-4, a new member of the E2F gene family has oncogenic activity and associates with p107 in vivo. Genes Dev., 8: 2680-2690, 1994.
11. Ginsberg, D., Vairo, G., Chittenden, T., Xiao, Z. X., Xu, G., Wydner, K. L., DeCaprio, J. A., Lawrence, J. B., and Livingston, D. M. E2F-4, a new member of the E2F transcription factor family interacts with p107. Genes Dev., 8: 2665-2679, 1994.
12. Sardet, C., Vidal, M., Cobrinik, D., Geng, Y., Onufryk, C., Chen, A., and Weinberg, R. A. E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc. Natl. Acad. Sci. USA, 92: 2403-2407, 1995.
13. Wu, C. L., Zukerberg, L. R., Ngwu, C., Harlow, E., and Lees, J. A. In vivo association of E2F and DP family proteins. Mol. Cell. Biol., 15: 2536-2546, 1995.
14. Bandara, L. R., Buck, V. M., Zamanian, M., Johnston, L. H., and La Thangue, N. B. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J., 12: 4317-4324, 1993.
15. Helin, K., Wu, C. L., Fattaey, A. R., Lees, J. A., Dynlacht, B. D., Ngwu, C., and Harlow, E. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev., 7: 1850-1861, 1993.
16. Helin, K., and Harlow, E. Heterodimerization of the transcription factors E2F-1 and DP-1 is required for binding to the adenovirus E4 (ORF6/7) protein. J. Virol., 68: 5027-5035, 1994.
17. Johnson, D. G., Schwarz, J. K., Cress, W. D., and Nevins, J. R. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (Lond.), 365: 349-352, 1993.
18. Zhu, L., van den Heuvel, S., Helin, K., Fattaey, A., Ewen, M., Livingston, D., Dyson, N., and Harlow, E. Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes Dev. 7: 1111-1125, 1993.
19. Qin, X. Q., Livingston, D. M., Kaelin, W., Jr., and Adams, P. D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA, 97: 10918-10922, 1994.
20. Shan, B., and Lee, W. H. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol., 14: 8166-8173, 1994.
21. Wu, X., and Levine, A. J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA, 91: 3602-3606, 1994.
22. Du, W., Xie, J-E., and Dyson, N. Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J., 75: 3684-3692, 1996.
23. Asano, M., Nevins, J. R., and Wharton, R. P. Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev., 70: 1422-1432, 1996.
24. Duronio, R. J., O'Farrell, P. H., Xie, J. E., Brook, A., and Dyson, N. The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev., 9: 1445-1455, 1995.
25. Brook, A., Xie, J-E., Du, W., and Dyson, N. Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J., 75: 3676-3683, 1996.
26. Chellapan, S., Hiebert, S., Mudryj, M., Horowitz, J., and Nevins, J. R. The E2F transcription factor is a cellular target for the RB protein. Cell, 65: 1053-1061, 1991.
27. Bagchi, S., Weinmann, R., and Raychaudhuri, P. The retinoblastoma protein copurifies with E2F-I, and E1A-regulated inhibitor of the transcription factor E2F. Cell, 65: 1063-1072, 1991.
28. Cao, L, Faha, B., Dembski, M., Tsai, L. H., Harlow, E., and Dyson, N. Independent binding of the retinoblastoma protein and p 107 to the transcription factor E2F. Nature (Lond.), 355: 176-179, 1992.
29. Devoto, S. H., Mudryj, M., Pines, J., Hunter, T., and Nevins, J. R. A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell, 68: 167-176, 1992.
30. Lees, E., Faha, B., Dulic, V., Reed, S. I., and Harlow, E. Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. Genes Dev., 6: 1874-1885, 1992.
31. S. Shirodkar, M. Ewen, J. A. DeCaprio, J. Morgan, D. M. Livingston, T. Chittenden. The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell 68: 157-166, 1992.
32. D. Cobrinik, P. Whyte, D. S. Peeper, T. Jacks, R. A. Weinberg. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev 7: 2392-2404, 1993.
33. Dimri, G. P., Hara, E., and Campisi, J. Regulation of two E2F-related genes in presenescent and senescent human fibroblasts. J. Biol. Chem., 269: 16180-16186, 1994.
34. Rieber, M., and Rieber, M. S. Cyclin-dependent kinase 2 and cyclin A interaction with E2F are targets for tyrosine induction of B16 melanoma terminal differentiation. Cell Growth Differ., 5: 1339-1346, 1994.
35. Philpott, A., and Friend, S. H. E2F and its developmental regulation in Xenopus laevis. Mol. Cell. Biol., 14: 5000-5009, 1994.
36. Buchkovich, K. J., and Ziff, E. B. Nerve growth factor regulates the expression and activity of p33cdk2 and p34cdc2 kinases in PC12 pheochromocytoma cells. Mol. Biol. Cell, 5: 1225-1241, 1994.
37. Kiyokawa, H., Richon, V. M., Rifkind, R. A., and Marks, P. A. Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. Mol. Cell. Biol. 14: 7195-7203, 1994.
38. Kranenburg, O., de Groot, R. P., Van der Eb, A. J., and Zantema, A. Differentiation of P19EC cells leads to differential modulation of cyclin-dependent kinase activities and to changes in the cell cycle profile. Oncogene, 70:87-95, 1995.
39. Darville, M. I., Antoine, I. V., Mertens-Strijthagen, J. R., Dupriez, V. J., and Rousseau, G. G. An E2F-dependent late-serum-response promoter in a gene that controls glycolysis. Oncogene, 11: 1509-1517, 1995.
40. Kranenburg, O., Scharnhorst, V., Van der Eb, A. J., and Zantema, A. Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells. J. Cell. Biol., 131: 227-234, 1995.
41. Guy, C. T., Zhou, W., Kaufman, S., and Robinson, M. O. E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytes. Mol. Cell. Biol. 76: 685-693, 1996.
42. Shin, E. K., Shin, A., Paulding, C., Schaffhausen, B., and Yee, A. S. Multiple changes in E2F function and regulation occur upon muscle differentiation. Mol. Cell. Biol. 15: 2252-2262, 1995.
43. Richon, V. M., and Venta-Perez, G. Changes in E2F DNA-binding activity during induced erythroid differentiation. Cell Growth Differ., 7: 31-42, 1996.
44. Tevosian, S. G., Paulson, K. E., Bronson, R., and Yee, A. S. Expression of E2F-1/DP-1 transcription factor in murine development. Cell Growth Differ., 7: 43-52, 1996.
45. Johnson, D. G., Ohtani, K., and Nevins, J. R. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev., 8: 1514-1525, 1994.
46. Hsiao, K. M., McMahon, S. L., and Farnham, P. J. Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev., 8: 1526-1537, 1994.
47. Sears, R. C., and Nevins, J. R. Regulation of the E2F2 and E2F3 gene promoters during the cell cycle. J. Cell. Biochem., 19A (Suppl.): 77, 1995.
48. Zinkel, S., and Fuchs, E. Skin cancer and transgenic mice. Semin. Cancer Biol., 5: 77-90, 1994.
49. Fuchs, E., and Byrne, C. The epidermis: rising to the surface. Curr. Opin. Genet. Dev., 4: 725-736, 1994.
50. Gordon, J. I., and Herminston, M. L. Differentiation and self-renewal in the mouse gastrointestinal epithelium. Curr. Opin. Cell Biol., 6: 795-803, 1994.
51. Simon, T. C., and Gordon, J. I. Intestinal epithelial cell differentiation: new insights from mice, flies and nematodes. Curr. Opin. Genet. Dev., 5: 577-586, 1995.
52. Byrne, C., Tainsky, M., and Fuchs, E. Programming gene expression in developing epidermis. Development (Camb.), 120: 2369-2383, 1994.
53. Lyons, K. M., Pelton, R. W., and Hogan, B. L. M. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-β-like genes coordinately regulate aspects of embryonic development. Genes Dev., 3: 1657-1668, 1989.
54. Moberg, K., Starz, M. A., and Lees, J. A. E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry. Mol. Cell. Biol. 16: 1436-1449, 1996.
55. Vairo, G., Livingston, D. M., and Ginsberg, D. Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes Dev., 9: 869-881, 1995.
56. Hijmans, E. M., Voorhoeve, P. M., Beijersbergen, R. L., van't Veer, L. J., and Bernards, R. E2F-5, a new E2F family member that interacts with p130 in vivo. Mol. Cell. Biol., 75: 3082-3089, 1995.
57. Satterwhite, D. J., Aakre, M. E., Gorska, A. E., and Moses, H. L. Inhibition of cell growth by TGFb1 is associated with inhibition of B-myb and cyclin A in both BALB/MK and Mv1Lu cells. Cell Growth Differ., 5: 789-799, 1994.
58. Pagano, M., Durst, M., Joswig, S., Draetta, G., and Jansen-Durr, P. Binding of the human E2F transcription factor to the retinoblastoma protein but not to cyclin A is abolished in HPV-16-immortalized cells. Oncogene, 7: 1681-1686, 1992.
59. Melillo, R. M., Helin, K., Lowy, D. R., and Schiller, J. T. Positive and negative regulation of cell proliferation by E2F-1: influence of protein level and human papillomavirus oncoproteins. Mol. Cell. Biol., 14: 8241-8249, 1994.
60. Cobrinik, D., Lee, M. H., Hannon, G., Mulligan, G., Bronson, R. T., Dyson, N., Harlow, E., Beach, D., Weinberg, R., and Jacks, T. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev., 10: 1633-1644, 1996.
61. Li, Y., Slansky, J. E., Myers, D. J., Drinkwater, N. R., Kaelin, W. G., and Farnham, P. J. Cloning, chromosomal location, and characterization of mouse E2F1. Mol. Cell. Biol., 14: 1861-1869, 1994.
62. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
63. Danielson, P. E., Fross-Petter, S., and Brow, A. p1B15: a cDNA clone of the rat mRNA encoding cyclophilin. DNA, 7: 261-267, 1988.
64. Hui, C-C., and Joyner, A. L. A mouse model of Greig cephalopolysyndactyly syndrome: the extra-toes mutation contains an intragenic deletion of the Gli3 gene. Nat. Genet., 3: 241-244, 1993.