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Volumn 30, Issue 3-4, 1997, Pages 97-105

E2F transcription factor action, regulation and possible role in human cancer

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR E2F;

EID: 0030782340     PISSN: 09607722     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2184.1997.tb00926.x     Document Type: Review
Times cited : (25)

References (51)
  • 1
    • 0024439444 scopus 로고
    • The retioblastoma protein is phosphorylated during specific phases of the cell cycle
    • BUCHKOVICH K, DUFFY LA, HARLOW E. (1989) The retioblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58, 1097.
    • (1989) Cell , vol.58 , pp. 1097
    • Buchkovich, K.1    Duffy, L.A.2    Harlow, E.3
  • 2
    • 0024429019 scopus 로고
    • Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
    • CHEN P-L, SCULLY P, SHEW J-Y, WANG JYJ, LEE W-H. (1989) Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 58, 1193.
    • (1989) Cell , vol.58 , pp. 1193
    • Chen, P.-L.1    Scully, P.2    Shew, J.-Y.3    Wang, J.Y.J.4    Lee, W.-H.5
  • 3
    • 0024418207 scopus 로고
    • The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
    • DECAPRIO JA, LUDLOW JW, LYNCH D et al. (1989) The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 58, 1085.
    • (1989) Cell , vol.58 , pp. 1085
    • Decaprio, J.A.1    Ludlow, J.W.2    Lynch, D.3
  • 6
    • 0030039801 scopus 로고    scopus 로고
    • Transcriptional control of cell growth: The E2F gene family
    • FARNHAM PJ, ed. (1996) Transcriptional control of cell growth: the E2F gene family. Curr. Top. Microbiol. Immunol. 208, 1-137.
    • (1996) Curr. Top. Microbiol. Immunol. , vol.208 , pp. 1-137
    • Farnham, P.J.1
  • 8
    • 0029949784 scopus 로고    scopus 로고
    • E2F-1 functions in mice to promote apoptosis and suppress proliferation
    • FIELD SJ, TSAI F-Y, KUO F et al. (1996) E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85, 549.
    • (1996) Cell , vol.85 , pp. 549
    • Field, S.J.1    Tsai, F.-Y.2    Kuo, F.3
  • 9
    • 0027520469 scopus 로고
    • The retinoblastoma protein binds E2F residues required for activation in vivo and TBp binding in vitro
    • HAGEMEIER C, COOK A, KOUZARIDES T. (1993) The retinoblastoma protein binds E2F residues required for activation in vivo and TBp binding in vitro. Nucleic Acids Res. 21, 4998.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4998
    • Hagemeier, C.1    Cook, A.2    Kouzarides, T.3
  • 10
    • 0029921317 scopus 로고    scopus 로고
    • Genetic alterations of cyclins, cyclin-dependent kinases, and cdk inhibitors in human cancer
    • HALL M, PETERS G. (1996) Genetic alterations of cyclins, cyclin-dependent kinases, and cdk inhibitors in human cancer. Adr. Cancer Res. 68, 67.
    • (1996) Adr. Cancer Res. , vol.68 , pp. 67
    • Hall, M.1    Peters, G.2
  • 11
    • 0029898213 scopus 로고    scopus 로고
    • A research shortcut from a common cold virus to human cancer
    • HARLOW E. (1996) A research shortcut from a common cold virus to human cancer. Cancer 78, 558.
    • (1996) Cancer , vol.78 , pp. 558
    • Harlow, E.1
  • 13
    • 0027489384 scopus 로고
    • Clinical implications of the p53 tumor-suppressor gene
    • HARRIS CC, HOLLSTEIN M. (1993) Clinical implications of the p53 tumor-suppressor gene. N. Engl. J. Med. 329, 1318.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1318
    • Harris, C.C.1    Hollstein, M.2
  • 15
    • 15444353328 scopus 로고    scopus 로고
    • pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes
    • HURFORD JR. RK, COBRINIK D, LEE M-H, DYSON N. (1997) pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev. 11, 1447.
    • (1997) Genes Dev. , vol.11 , pp. 1447
    • Hurford Jr., R.K.1    Cobrinik, D.2    Lee, M.-H.3    Dyson, N.4
  • 17
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • JOHNSON DG, SCHWARZ JK, CRESS WD, NEVINS JR. (1993) Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 365, 349.
    • (1993) Nature , vol.365 , pp. 349
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 18
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • KOWALIK TF, DEGREGORI J, SCHWARZ JK, NEVINS JR. (1995) E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. Mol Cell Biol. 69, 2491.
    • (1995) Mol Cell Biol. , vol.69 , pp. 2491
    • Kowalik, T.F.1    Degregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 19
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • KREK W, EWEN ME, SHIRODKAR S, ARANY Z, KAELIN WG, JR., LIVINGSTON DM. (1994) Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78, 161.
    • (1994) Cell , vol.78 , pp. 161
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin Jr., W.G.5    Livingston, D.M.6
  • 20
    • 0028267869 scopus 로고
    • DRTF-1/E2F: An expanding family of hetero-dimeric transcription factors implicated in cell cycle control
    • LA THANGUE NB. (1994) DRTF-1/E2F: an expanding family of hetero-dimeric transcription factors implicated in cell cycle control. Trends Biochem. Sci. 19, 108.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 108
    • La Thangue, N.B.1
  • 21
    • 0027316813 scopus 로고
    • An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
    • LAM EW-F, WATSON RJ. (1993) An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J. 12, 2705.
    • (1993) EMBO J. , vol.12 , pp. 2705
    • Lam, E.W.-F.1    Watson, R.J.2
  • 22
    • 0030038279 scopus 로고    scopus 로고
    • Cell cycle-regulated repression of B-myb transcription: Cooperation of an E2F site with a contiguous corepressor element
    • LIU N, LUCIBELLO FC. (1996) Cell cycle-regulated repression of B-myb transcription: cooperation of an E2F site with a contiguous corepressor element. Nucleic Acids Res. 24, 2905.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2905
    • Liu, N.1    Lucibello, F.C.2
  • 23
    • 0025060176 scopus 로고
    • The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T
    • LUDLOW JW, SHON J, PIPAS JM, LIVINGSTON DM, DECAPRIO JA. (1990) The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. Cell 60, 387.
    • (1990) Cell , vol.60 , pp. 387
    • Ludlow, J.W.1    Shon, J.2    Pipas, J.M.3    Livingston, D.M.4    Decaprio, J.A.5
  • 24
    • 0030053130 scopus 로고    scopus 로고
    • Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression
    • LUKAS J, PETERSEN BO, HOLM K, BARTEK J, HELIN K. (1996) Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression. Mol Cell Biol. 16, 1047.
    • (1996) Mol Cell Biol. , vol.16 , pp. 1047
    • Lukas, J.1    Petersen, B.O.2    Holm, K.3    Bartek, J.4    Helin, K.5
  • 25
    • 0024851254 scopus 로고
    • Cell cycle dependent regulation of phosphorylation of the human retinoblastoma gene product
    • MIHARA K, CAO XR, YEN A et al. (1989) Cell cycle dependent regulation of phosphorylation of the human retinoblastoma gene product. Science 246, 1300.
    • (1989) Science , vol.246 , pp. 1300
    • Mihara, K.1    Cao, X.R.2    Yen, A.3
  • 26
    • 0026529607 scopus 로고
    • Three distinct elements within the murine c-myc promoter are required for transcription
    • MOBERG KH, LOGAN TJ, TYNDALL WA, HALL DJ. (1992) Three distinct elements within the murine c-myc promoter are required for transcription. Oncogens 7, 411.
    • (1992) Oncogens , vol.7 , pp. 411
    • Moberg, K.H.1    Logan, T.J.2    Tyndall, W.A.3    Hall, D.J.4
  • 27
    • 0029739541 scopus 로고    scopus 로고
    • Retinoblastoma protein family in cell cycle and cancer: A review
    • PAGGI MG, BALDI A, BONETTO F, GIORDANO A. (1996) Retinoblastoma protein family in cell cycle and cancer: a review. J. Cell. Biochem. 62, 418.
    • (1996) J. Cell. Biochem. , vol.62 , pp. 418
    • Paggi, M.G.1    Baldi, A.2    Bonetto, F.3    Giordano, A.4
  • 28
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • QIN X-Q, LIVINGSTON DM, KAELIN, JR. WG, ADAMS PD. (1994) Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA 91, 10918.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10918
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin Jr., W.G.3    Adams, P.D.4
  • 29
    • 0028909272 scopus 로고
    • Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line
    • SAITO M, HELIN K, VALENTINE MB et al. (1995) Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line. Genomics 25, 130.
    • (1995) Genomics , vol.25 , pp. 130
    • Saito, M.1    Helin, K.2    Valentine, M.B.3
  • 30
    • 0028210789 scopus 로고
    • Correlation between E2F-1 requirement in the S phase and E2F-1 transactivation of cell cycle-related genes in human cells
    • SALA A, NICOLAIDES NC, ENGELHARD A et al. (1994) Correlation between E2F-1 requirement in the S phase and E2F-1 transactivation of cell cycle-related genes in human cells. Cancer Res. 54, 1402.
    • (1994) Cancer Res. , vol.54 , pp. 1402
    • Sala, A.1    Nicolaides, N.C.2    Engelhard, A.3
  • 32
    • 0030069682 scopus 로고    scopus 로고
    • Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis
    • SHAN B, DURFEE T, LEE WH. (1996) Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis. Proc. Natl. Acad. Sci. USA 93, 679.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 679
    • Shan, B.1    Durfee, T.2    Lee, W.H.3
  • 33
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • SHERR CJ. (1996) Cancer cell cycles. Science 274, 1672.
    • (1996) Science , vol.274 , pp. 1672
    • Sherr, C.J.1
  • 34
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • SINGH P, WONG SH, HONG W. (1994) Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J. 13, 3329.
    • (1994) EMBO J. , vol.13 , pp. 3329
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 35
    • 0030436262 scopus 로고    scopus 로고
    • Established cell lines transformed by E2F-1 overexpression contain wild-type p53
    • SLADEK TL. (1996) Established cell lines transformed by E2F-1 overexpression contain wild-type p53. Cell Prolif. 29, 579.
    • (1996) Cell Prolif. , vol.29 , pp. 579
    • Sladek, T.L.1
  • 36
    • 11944270727 scopus 로고    scopus 로고
    • Introduction to the E2F family: Protein structure and gene regulation
    • SLANSKY JE, FARNHAM PJ. (1996) Introduction to the E2F family: protein structure and gene regulation. Curr. Top. Microbiol. Immunol. 208, 1.
    • (1996) Curr. Top. Microbiol. Immunol. , vol.208 , pp. 1
    • Slansky, J.E.1    Farnham, P.J.2
  • 37
    • 0028031256 scopus 로고
    • DNA synthesis is induced in adult neurons after expression of E2F1 and E1A
    • SUDA K, HOLMBERG EG, NORNES HO, NEUMAN T. (1994) DNA synthesis is induced in adult neurons after expression of E2F1 and E1A. Neuroreport 5, 1749.
    • (1994) Neuroreport , vol.5 , pp. 1749
    • Suda, K.1    Holmberg, E.G.2    Nornes, H.O.3    Neuman, T.4
  • 38
    • 0031016121 scopus 로고    scopus 로고
    • RB kinases and RB-binding proteins: New points of view
    • TAYA Y. (1997) RB kinases and RB-binding proteins: new points of view. Trends Biochem. Sci. 22, 14.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 14
    • Taya, Y.1
  • 39
    • 0024651359 scopus 로고
    • Nuclear factor E2F mediates basic transcription and trans-activation of E1a of the human MYC promoter
    • THALMEIER K, SYNOVZIK H, MERTZ R, WINNACKER E-L, LIPP M. (1989) Nuclear factor E2F mediates basic transcription and trans-activation of E1a of the human MYC promoter. Genes Dev. 3, 527.
    • (1989) Genes Dev. , vol.3 , pp. 527
    • Thalmeier, K.1    Synovzik, H.2    Mertz, R.3    Winnacker, E.-L.4    Lipp, M.5
  • 40
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • WEINBERG RA. (1995) The retinoblastoma protein and cell cycle control. Cell 81, 323.
    • (1995) Cell , vol.81 , pp. 323
    • Weinberg, R.A.1
  • 41
    • 0029977751 scopus 로고    scopus 로고
    • E2F and cell proliferation: A world turned upside down
    • WEINBERG RA. (1996) E2F and cell proliferation: a world turned upside down. Cell 85, 457.
    • (1996) Cell , vol.85 , pp. 457
    • Weinberg, R.A.1
  • 42
    • 0029043782 scopus 로고
    • Mechanism of active transcriptional repression by the retinoblastoma protein
    • WEINTRAUB SJ, CHOW KNB, LUO RX, ZHANG SH, HE S, DEAN DC. (1995) Mechanism of active transcriptional repression by the retinoblastoma protein. Nature 375, 812.
    • (1995) Nature , vol.375 , pp. 812
    • Weintraub, S.J.1    Chow, K.N.B.2    Luo, R.X.3    Zhang, S.H.4    He, S.5    Dean, D.C.6
  • 43
    • 0031051550 scopus 로고    scopus 로고
    • Accumulation of E2F-4.DP-1 DNA binding complexes correlates with induction of dhfr gene expression during the G1 to S phase transition
    • WELLS JM, ILLENYE S, MAGAE J, WU CL, HEINTZ NH. (1997) Accumulation of E2F-4.DP-1 DNA binding complexes correlates with induction of dhfr gene expression during the G1 to S phase transition. J. Biol. Chem. 272, 4483.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4483
    • Wells, J.M.1    Illenye, S.2    Magae, J.3    Wu, C.L.4    Heintz, N.H.5
  • 44
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • WU X, LEVINE AJ. (1994) p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA 91, 3602.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3602
    • Wu, X.1    Levine, A.J.2
  • 45
    • 0028945789 scopus 로고
    • Multiple members of the E2F transcription factor family are the products of oncogenes
    • XU G, LIVINGSTON DM, KREK W. (1995) Multiple members of the E2F transcription factor family are the products of oncogenes. Proc. Natl. Acad. Sci. USA 92, 1357.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1357
    • Xu, G.1    Livingston, D.M.2    Krek, W.3
  • 47
    • 0029105092 scopus 로고
    • Overexpression of the E2F-1 transcription factor gene mediates cell transformation
    • YANG XH, SLADEK TL. (1995) Overexpression of the E2F-1 transcription factor gene mediates cell transformation. Gene Expr. 4, 195.
    • (1995) Gene Expr. , vol.4 , pp. 195
    • Yang, X.H.1    Sladek, T.L.2
  • 48
    • 0030583609 scopus 로고    scopus 로고
    • Mutations of E2F-4 trinucleotide repeats in colorectal cancer with microsatellite instability
    • YOSHITAKA T, MATSUBARA N, IKEDA M et al. (1996) Mutations of E2F-4 trinucleotide repeats in colorectal cancer with microsatellite instability. Biochem. Diophys. Res. Commun. 227, 553.
    • (1996) Biochem. Diophys. Res. Commun. , vol.227 , pp. 553
    • Yoshitaka, T.1    Matsubara, N.2    Ikeda, M.3
  • 50
    • 0029079936 scopus 로고
    • Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechansim of transcriptional repression
    • ZWICKER J, LUCIBELLO FC, WOLFRAIM LA et al. (1995) Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechansim of transcriptional repression. EMBO J. 14, 4514.
    • (1995) EMBO J. , vol.14 , pp. 4514
    • Zwicker, J.1    Lucibello, F.C.2    Wolfraim, L.A.3
  • 51
    • 0031054892 scopus 로고    scopus 로고
    • Cell-cycle regulation of gene expression by transcriptional repression
    • ZWICKER J, MÜLLER R. (1997) Cell-cycle regulation of gene expression by transcriptional repression. Trends Genet. 13, 3.
    • (1997) Trends Genet. , vol.13 , pp. 3
    • Zwicker, J.1    Müller, R.2


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