Growth inhibition of cultured human Tenon's fibroblastic cells by targeting the E2F transcription factor

Experimental Eye Research

Volumn 67, Issue 4, 1998, Pages 395-401

  Akimoto, Masayuki ^a,b   Hangai, Masanori ^a   Okazaki, Kazushiro ^a   Kogishi, Junichi ^a   Honda, Yoshihito ^a   Kaneda, Yasufumi ^c  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Cellular proliferation; E2F; HVJ CL; Phosphorothioate oligonucleotides decoy; Transcription factor

Indexed keywords

DNA; OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID; TRANSCRIPTION FACTOR E2F;

ARTICLE; CELL CYCLE; CELL PROLIFERATION; FIBROBLAST; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VITREORETINOPATHY;

EID: 0032191333     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0531     Document Type: Article

References (35)

1. Bielinska A., Shivdasani R. A., Zhang L. Q., Nabel G. J. Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science. 250:1990;997-1000.
2. Blake M. C., Azizkhan J. C. Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo. Mol. Cell. Biol. 9:1989;4994-5002.
3. Chu E., Takechi T., Jones K. L., Voeller D. M., Copur S. M., Maley G. F., Maley F., Segal S., Allegra C. J. Thymidylate synthase binds to c-myc RNA in human colon cancer cells and in vitro. Mol. Cell. Biol. 15:1995;179-185.
4. Dalton S. Cell cycle regulation of the human cdc2 gene. Embo. J. 21:1992;11, 1797-804.
5. DeGregori J., Kowalik T., Nevins J. R. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol. Cell. Biol. 15:1995;4215-4224.
6. Dignam J. D., Martin P. L., Shastry B. S., Roeder R. G. Eukaryotic gene transcription with purified components. Methods Enzymol. 101:1983;582-598.
7. Farnham P. J., Schimke R. T. Transcriptional regulation of mouse dihydrofolate reductase in the cell cycle. J. Biol. Chem. 260:1985;7675-7680.
8. Furukawa Y., Terui Y., Sakoe K., Ohta M., Saito M. The role of cellular transcription factor E2F in the regulation of cdc2 mRNA expression and cell cycle control of human hematopoietic cells. J. Biol. Chem. 269:1994;26249-26258.
9. Gao X., Huang L. A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem. Biophys. Res. Commun. 179:1991;280-285.
10. Gillardon F., Zimmermann M., Uhlmann E. Expression of c-Fos and c-Jun in the cornea, lens, and retina after ultraviolet irradiation of the rat eye and effects of topical antisense oligodeoxynucleotides. Br. J. Ophthalmol. 79:1995;277-281.
11. Hangai M., Kaneda Y., Tanihara H., Honda Y. In vivo gene transfer into the retina mediated by a novel liposome system. Invest. Ophthalmol. Vis. Sci. 37:1997;2678-2685.
12. Hennighausen L., Lubon H. Interaction of protein with DNA in vitro. Methods Enzymol. 152:1987;721-735.
13. Hiebert S. W., Lipp M., Nevins J. R. E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. Proc. Natl. Acad. Sci., USA. 86:1989;3594-3598.
14. Ishizaki J., Nevins J. R., Sullenger B. A. Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. Nat. Med. 2:1996;1386-1389.
15. Jones S. E., McHugh J. D., Jomary C., Shallal A., Neal M. J. Assessment of liposomal transfection of ocular tissues in vivo. Gene Ther. 1 (Suppl 1):1994;S61.
16. Masuda I., Matsuo T., Yasuda T., Matsuo N. Gene transfer with liposomes to the intraocular tissues by different routes of administration. Invest. Ophthalmol. Vis. Sci. 37:1996;1914-1920.
17. Matsuo T., Masuda I., Yasuda T., Matsuo N. Gene transfer to the retina of rat by liposome eye drops. Biochem. Biophys. Res. Commun. 219:1996;947-950.
18. Morishita R., Gibbons G. H., Horiuchi M., Ellison K. E., Nakama M., Zhang L., Kaneda Y., Ogihara T., Dzau V. J. A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc. Natl. Acad. Sci. USA. 92:1995;5855-5859.
19. Morishita R., Gibbons G. H., Kaneda Y., Ogihara T., Dzau V. J. Pharmacokinetics of antisense oligodeoxyribonucleotides (cyclin B1 and CDC2 kinase) in the vessel wall in vivo: enhanced therapeutic utility for restenosis by HVJ-liposome delivery. Gene. 149:1994;13-19.
20. Nishikura K. Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes. Mol. Cell. Biol. 6:1986;4093-4098.
21. Reiss K., Porcu P., Sell C., Pietrzkowski Z., Baserga R. The insulin-like growth factor 1 receptor is required for the proliferation of hemopoietic cells. Oncogene. 7:1992;2243-2248.
22. Robinson G. S., Pierce E. A., Rook S. L., Foley E., Webb R., Smith L. E. Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy. Proc. Natl. Acad. Sci. USA. 93:1996;4851-4856.
23. Saeki Y., Matsumoto N., Nakano Y., Mori M., Awai K., Kaneda Y. Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): Reciprocal effect of cationic lipid for in vitro and in vivo gene transfer. Hum. Gene Ther. 8:1998;1965-1972.
24. Saiki R. K., Gelfand D. H., Stoffel S., Scharf S. J., Higuchi R., Horn G. T., Mullis K. B., Erlich H. A. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science. 239:1988;487-491.
25. Senior J. H., Trimble K. R., Maskiewicz R. Interaction of positively-charged liposomes with blood: implications for their application in vivo. Biochim. Biophys. Acta. 1070:1991;173-179.
26. Smetsers T. F., Linders E. H., van-de-Locht L. T., de-Witte T. M., Mensink E. J. An antisense Bcr-Abl phosphodiester-tailed methylphosphonate oligonucleotide reduces the growth of chronic myeloid leukaemia patient cells by a non-antisense mechanism. Br. J. Haematol. 96:1997;377-381.
27. Sullenger B. A., Gallardo H. F., Ungers G. E., Gilboa E. Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication. Cell. 63:1990;601-608.
28. Thalmeier K., Synovzik H., Mertz R., Winnacker E. L., Lipp M. Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter. Genes Dev. 3:1989;527-536.
29. Tomita N., Higaki J., Ogihara T., Kondo T., Kaneda Y. A novel gene-transfer technique mediated by HVJ (Sendai virus), nuclear protein, and liposomes. Cancer Detect. Prev. 18:1994;485-491.
30. Wang W., Chen H. J., Schwartz A., Cannon P. J., Stein C. A., Rabbani L. E. Sequence-independent inhibition of in vitro vascular smooth muscle cell proliferation, migration, and in vivo neointimal formation by phosphorothioate oligodeoxynucleotides. J. Clin. Invest. 98:1996;443-450.
31. Yagi K., Noda H., Kurono M., Ohishi N. Efficient gene transfer with less cytotoxicity by means of cationic multilamellar liposomes. Biochem. Biophys. Res. Commun. 196:1993;1042-1048.
32. Yamaguchi M., Hayashi Y., Hirose F., Matsuoka S., Shiroki K., Matsukage A. Activation of the mouse proliferating cell nuclear antigen gene promoter by adenovirus type 12 E1A proteins. Jpn. J. Cancer Res. 83:1992;609-617.
33. Yamaguchi M., Hayashi Y., Matsukage A. Essential role of E2F recognition sites in regulation of the proliferating cell nuclear antigen gene promoter during Drosophila development. J. Biol. Chem. 270:1995;25159-25165.
34. Yoshida M., Yoshimura N., Hangai M., Tanihara H., Honda Y. Interleukin-1 alpha, interleukin-1 beta, and tumor necrosis factor gene expression in endotoxin-induced uveitis. Invest. Ophthalmol. Vis. Sci. 35:1994;1107-1113.
35. Zwicker J., Liu N., Engeland K., Lucibello F. C., Muller R. Cell cycle regulation of E2F site occupation in vivo. Science. 271:1996;1595-1597.