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Volumn 10, Issue 23, 1996, Pages 2960-2970

Degradation of E2F by the ubiquitin-proteasome pathway: Regulation by retinoblastoma family proteins and adenovirus transforming proteins

Author keywords

cell cycle; E2F; ubiquitin

Indexed keywords

PROTEASOME; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR; UBIQUITIN; VIRUS PROTEIN;

EID: 0029797841     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.23.2960     Document Type: Article
Times cited : (192)

References (63)
  • 1
    • 0029971218 scopus 로고    scopus 로고
    • Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins
    • Beijersbergen, R.L. and R. Bernards. 1996. Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins. Biochem. Biophys. Act 1287: 103-120.
    • (1996) Biochem. Biophys. Act , vol.1287 , pp. 103-120
    • Beijersbergen, R.L.1    Bernards, R.2
  • 2
    • 0027985749 scopus 로고
    • E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo
    • Beijersbergen, R.L., R. Kerkhoven, L. Zhu, L. Carlée, P.M. Voorhoeve, and R. Bernards. 1994. E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes & Dev. 8: 2680-2690.
    • (1994) Genes & Dev. , vol.8 , pp. 2680-2690
    • Beijersbergen, R.L.1    Kerkhoven, R.2    Zhu, L.3    Carlée, L.4    Voorhoeve, P.M.5    Bernards, R.6
  • 3
    • 0029031349 scopus 로고
    • Regulation of the retinoblastoma-related p107 by G1 cyclin complexes
    • Beijersbergen, R.L., L. Cariée, R.M. Kerkhoven, and R. Bernards. 1995. Regulation of the retinoblastoma-related p107 by G1 cyclin complexes. Genes & Dev. 9: 1340-1353.
    • (1995) Genes & Dev. , vol.9 , pp. 1340-1353
    • Beijersbergen, R.L.1    Cariée, L.2    Kerkhoven, R.M.3    Bernards, R.4
  • 4
    • 0019970985 scopus 로고
    • Characterization of cells transformed by Ad5/ Ad12 hybrid early region 1 plasmids
    • Bernards, R., A. Houweling, P.I. Schrier, J.L. Bos, and A.J. Van der Eb. 1982. Characterization of cells transformed by Ad5/ Ad12 hybrid early region 1 plasmids. Virology 120: 422-432.
    • (1982) Virology , vol.120 , pp. 422-432
    • Bernards, R.1    Houweling, A.2    Schrier, P.I.3    Bos, J.L.4    Van der Eb, A.J.5
  • 7
    • 0024514688 scopus 로고
    • A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
    • Chau, V., J.W. Tobias, A. Bachmair, D. Marriott, D.J. Ecker, D.K. Gonda, and A. Varshavsky. 1989. A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science 243: 1576-1583.
    • (1989) Science , vol.243 , pp. 1576-1583
    • Chau, V.1    Tobias, J.W.2    Bachmair, A.3    Marriott, D.4    Ecker, D.J.5    Gonda, D.K.6    Varshavsky, A.7
  • 8
    • 0027299921 scopus 로고
    • Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F
    • Chittenden, T., D.M. Livingston, and J.A. DeCaprio. 1993. Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. Mol. Cell. Biol. 13: 3975-3983.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3975-3983
    • Chittenden, T.1    Livingston, D.M.2    DeCaprio, J.A.3
  • 9
    • 0029957947 scopus 로고    scopus 로고
    • Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation
    • Clurman, B.E., R.J. Sheaff, K. Thress, M. Groudine, and J.A. Roberts. 1996. Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. Genes & Dev. 10: 1979-1990.
    • (1996) Genes & Dev. , vol.10 , pp. 1979-1990
    • Clurman, B.E.1    Sheaff, R.J.2    Thress, K.3    Groudine, M.4    Roberts, J.A.5
  • 10
    • 0027140404 scopus 로고
    • Cell cycle-specific association of E2F with the p 130 E1A-binding protein
    • Cobrinik, D., P. Whyte, D.S. Peeper, T. Jacks, and R.A. Weinberg. 1993. Cell cycle-specific association of E2F with the p 130 E1A-binding protein. Genes & Dev. 7: 2392-2404.
    • (1993) Genes & Dev. , vol.7 , pp. 2392-2404
    • Cobrinik, D.1    Whyte, P.2    Peeper, D.S.3    Jacks, T.4    Weinberg, R.A.5
  • 11
    • 0029049577 scopus 로고
    • Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- And G1/S-regulatory genes
    • Degregori, J., T. Kowalik, and J.R. Nevins. 1995. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol. Cell. Biol. 15: 4215-4224.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4215-4224
    • Degregori, J.1    Kowalik, T.2    Nevins, J.R.3
  • 12
    • 0028985013 scopus 로고
    • Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway
    • Deshaies, R.J., V. Chau, and M.W. Kirschner. 1995. Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway. EMBO J. 14: 303-312.
    • (1995) EMBO J. , vol.14 , pp. 303-312
    • Deshaies, R.J.1    Chau, V.2    Kirschner, M.W.3
  • 13
    • 0027204555 scopus 로고
    • Physical interaction of the retinoblastoma protein with Human D cyclins
    • Dowdy, F.D., P.W. Hinds, K. Louie, S.I. Reed, and R.A. Weinberg. 1993. Physical interaction of the retinoblastoma protein with Human D cyclins. Cell 73: 499-511.
    • (1993) Cell , vol.73 , pp. 499-511
    • Dowdy, F.D.1    Hinds, P.W.2    Louie, K.3    Reed, S.I.4    Weinberg, R.A.5
  • 14
    • 0027936686 scopus 로고
    • Differential regulation of E2F transactivation by cyclin/cdk2 complexes
    • Dynlacht, B.D., O. Flores, J.A. Lees, and E. Harlow. 1994. Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes & Dev. 8: 1772-1786.
    • (1994) Genes & Dev. , vol.8 , pp. 1772-1786
    • Dynlacht, B.D.1    Flores, O.2    Lees, J.A.3    Harlow, E.4
  • 15
    • 0027229136 scopus 로고
    • Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
    • Ewen, M.E., H.K. Sluss, C.J. Sherr, H. Matsushime, J. Kato, and D.M. Livingston. 1993. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell 73: 487-497.
    • (1993) Cell , vol.73 , pp. 487-497
    • Ewen, M.E.1    Sluss, H.K.2    Sherr, C.J.3    Matsushime, H.4    Kato, J.5    Livingston, D.M.6
  • 18
    • 0026089183 scopus 로고
    • Cyclin is degraded by the ubiquitin pathway
    • Glotzer, M., A.W. Murray, and M.W. Kirschner. 1991. Cyclin is degraded by the ubiquitin pathway. Nature 349: 132-138.
    • (1991) Nature , vol.349 , pp. 132-138
    • Glotzer, M.1    Murray, A.W.2    Kirschner, M.W.3
  • 19
    • 0028261956 scopus 로고
    • The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivo
    • Goebl, M.G., L. Goetsch, and B. Byers. 1994. The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivo. Mol. Cell. Biol. 14: 3022-3029.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3022-3029
    • Goebl, M.G.1    Goetsch, L.2    Byers, B.3
  • 20
    • 0020479562 scopus 로고
    • The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysis
    • Haas, A.L. and I.A. Rose. 1982. The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysis. J. Biol. Chem. 257: 10329-10337.
    • (1982) J. Biol. Chem. , vol.257 , pp. 10329-10337
    • Haas, A.L.1    Rose, I.A.2
  • 21
    • 0029957644 scopus 로고    scopus 로고
    • MUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect
    • Hateboer, G., E.M. Hijmans, J.B.D. Nooij, S. Schlenker, S. Jentsch, and R. Bernards. 1996. mUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect, J. Biol. Chem. 271: 25906-25911.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25906-25911
    • Hateboer, G.1    Hijmans, E.M.2    Nooij, J.B.D.3    Schlenker, S.4    Jentsch, S.5    Bernards, R.6
  • 22
    • 0026652346 scopus 로고
    • A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
    • Helin, K., J.A. Lees, M. Vidal, N. Dyson, E. Harlow, and A. Fattey. 1992. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 70: 337-350.
    • (1992) Cell , vol.70 , pp. 337-350
    • Helin, K.1    Lees, J.A.2    Vidal, M.3    Dyson, N.4    Harlow, E.5    Fattey, A.6
  • 23
    • 0024670325 scopus 로고
    • E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor
    • Hiebert, S.W., M. Lipp, zJ.R. Nevins. 1989. E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. Proc. Natl. Acad. Sci. 86: 3594-3598.
    • (1989) Proc. Natl. Acad. Sci. , vol.86 , pp. 3594-3598
    • Hiebert, S.W.1    Lipp, M.2    Nevins, J.R.3
  • 25
    • 0029867623 scopus 로고    scopus 로고
    • Proteasomes: Destruction as a programme
    • Hilt, W. and D.H. Wolf. 1996. Proteasomes: Destruction as a programme. Trends Biochem. Sci. 21: 96-102.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 96-102
    • Hilt, W.1    Wolf, D.H.2
  • 26
    • 0026802989 scopus 로고
    • Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
    • Hinds, P.W., S. Mittnacht, V. Dulic, A. Arnold, S.I. Reed, and R.A. Weinberg. 1992. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70: 993-1006.
    • (1992) Cell , vol.70 , pp. 993-1006
    • Hinds, P.W.1    Mittnacht, S.2    Dulic, V.3    Arnold, A.4    Reed, S.I.5    Weinberg, R.A.6
  • 27
    • 0028935165 scopus 로고
    • Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
    • Hochstrasser, M. 1995. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr. Opin. Cell Biol. 7: 215-223.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 215-223
    • Hochstrasser, M.1
  • 28
    • 0029820095 scopus 로고    scopus 로고
    • The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
    • this issue
    • Hofmann, F., F. Martelli, D.M. Livingston, and Z. Wang. 1996. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes & Dev. (this issue).
    • (1996) Genes & Dev.
    • Hofmann, F.1    Martelli, F.2    Livingston, D.M.3    Wang, Z.4
  • 29
    • 0027053491 scopus 로고
    • The ubiquitin-conjugation system
    • Jentsch, S. 1992. The ubiquitin-conjugation system. Annu. Rev. Genet. 26: 179-207.
    • (1992) Annu. Rev. Genet. , vol.26 , pp. 179-207
    • Jentsch, S.1
  • 30
    • 0029162583 scopus 로고
    • Selective protein degradation: A journey's end within the proteasome
    • Jentsch, S. and S. Schlenker. 1995. Selective protein degradation: A journey's end within the proteasome. Cell 82: 881-884.
    • (1995) Cell , vol.82 , pp. 881-884
    • Jentsch, S.1    Schlenker, S.2
  • 32
    • 0028364529 scopus 로고
    • Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression
    • Johnson, D.G., K. Ohtani, and J.R. Nevins. 1994b. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes & Dev. 8: 1514-1525.
    • (1994) Genes & Dev. , vol.8 , pp. 1514-1525
    • Johnson, D.G.1    Ohtani, K.2    Nevins, J.R.3
  • 34
    • 0028362359 scopus 로고
    • Negative regulation of the growth promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek, W., M.E. Ewen, S. Shirodkar, Z. Arany, W.G. Kaelin Jr., and D.M. Livingston. 1994. Negative regulation of the growth promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78: 161-172.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin Jr., W.G.5    Livingston, D.M.6
  • 35
    • 0029559027 scopus 로고
    • Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint
    • Krek, W., G. Xu, and D.M. Livingston. 1995. cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell 83: 1149-1158.
    • (1995) Cell , vol.83 , pp. 1149-1158
    • Krek, W.1    Xu, G.2    Livingston, D.M.3
  • 36
    • 0027316813 scopus 로고
    • An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
    • Lam, E.W. and R.J. Watson. 1993. An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J. 12: 2705-2713.
    • (1993) EMBO J. , vol.12 , pp. 2705-2713
    • Lam, E.W.1    Watson, R.J.2
  • 37
    • 0026701339 scopus 로고
    • Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p 107 and E2F in a temporally distinct manner
    • Lees, E., B. Faha, V. Dulic, S.I. Reed, and E. Harlow. 1992. Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p 107 and E2F in a temporally distinct manner. Genes & Dev. 6: 1874-1885.
    • (1992) Genes & Dev. , vol.6 , pp. 1874-1885
    • Lees, E.1    Faha, B.2    Dulic, V.3    Reed, S.I.4    Harlow, E.5
  • 38
    • 0028136903 scopus 로고
    • Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter
    • Neuman, E., E.K. Flemington, W.R. Sellers, and W.J. Kaelin. 1994. Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter. Mol. Cell Biol. 14: 6607-6615.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6607-6615
    • Neuman, E.1    Flemington, E.K.2    Sellers, W.R.3    Kaelin, W.J.4
  • 39
    • 0028356521 scopus 로고
    • E2F-depen- Dent regulation of human MYC: Trans-activation by cyclins D1 and A overrides tumour suppressor protein functions
    • Oswald, F., H. Lovec, T. Moroy, and M. Lipp. 1994. E2F-depen- dent regulation of human MYC: Trans-activation by cyclins D1 and A overrides tumour suppressor protein functions. Oncogene 9: 2029-2036.
    • (1994) Oncogene , vol.9 , pp. 2029-2036
    • Oswald, F.1    Lovec, H.2    Moroy, T.3    Lipp, M.4
  • 41
    • 0021996450 scopus 로고
    • Functional heterogeneity of ubiquitin carrier proteins
    • Pickart, C.M. and I.A. Rose. 1985. Functional heterogeneity of ubiquitin carrier proteins. J. Biol. Chem. 260: 1573-1581.
    • (1985) J. Biol. Chem. , vol.260 , pp. 1573-1581
    • Pickart, C.M.1    Rose, I.A.2
  • 42
    • 0028176483 scopus 로고
    • Cloning of p27Kipl, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • Polyak, K., M.H. Lee, B.H. Erdjument, A. Koff, J.M. Roberts, P. Tempst, and J. Massague. 1994. Cloning of p27Kipl, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.H.2    Erdjument, B.H.3    Koff, A.4    Roberts, J.M.5    Tempst, P.6    Massague, J.7
  • 43
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin, X.Q., D.M. Livingston, W.J. Kaelin, and P.D. Adams. 1994. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. 91: 10918-10922.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 10918-10922
    • Qin, X.Q.1    Livingston, D.M.2    Kaelin, W.J.3    Adams, P.D.4
  • 44
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock, K.L., C. Gramm, K. Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, and A.L. Goldberg. 1994. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78: 761-777.
    • (1994) Cell , vol.78 , pp. 761-777
    • Rock, K.L.1    Gramm, C.2    Rothstein, K.3    Clark, K.4    Stein, R.5    Dick, L.6    Hwang, D.7    Goldberg, A.L.8
  • 45
    • 0029353809 scopus 로고
    • Proteolysis. the proteasome: A protein-degrading organelle?
    • Rubin, D.M. and D. Finley. 1995. Proteolysis. The proteasome: A protein-degrading organelle? Curr. Biol. 5: 854-858.
    • (1995) Curr. Biol. , vol.5 , pp. 854-858
    • Rubin, D.M.1    Finley, D.2
  • 46
    • 0028948866 scopus 로고
    • E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle
    • Sardet, C., M. Vidai, D. Cobrinik, Y. Geng, C. Onufryk, A. Chen, and R.A. Weinberg. 1995. E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc. Natl. Acad. Sci. 92: 2403-2407.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 2403-2407
    • Sardet, C.1    Vidai, M.2    Cobrinik, D.3    Geng, Y.4    Onufryk, C.5    Chen, A.6    Weinberg, R.A.7
  • 47
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., J.M. Huibregtse, R.D. Vierstra, and P.M. Howley. 1993. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75: 495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 48
    • 0028114987 scopus 로고
    • The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae
    • Schwob, E., T. Bohm, M.D. Mendenhall, and K. Nasmyth. 1994. The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79: 233-244.
    • (1994) Cell , vol.79 , pp. 233-244
    • Schwob, E.1    Bohm, T.2    Mendenhall, M.D.3    Nasmyth, K.4
  • 49
    • 0028967267 scopus 로고
    • Role of a ubiquitin-conjugating enzyme in degradation of S- And M-phase cyclins
    • Seufert, W., B. Futcher, and S. Jentsch. 1995. Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins. Nature 373: 78-81.
    • (1995) Nature , vol.373 , pp. 78-81
    • Seufert, W.1    Futcher, B.2    Jentsch, S.3
  • 50
    • 0026530730 scopus 로고
    • The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner
    • Shirodkar, S., M. Ewen, J.A. DeCaprio, J. Morgan, D.M. Livingston, and T. Chittenden. 1992. The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell 68: 157-166.
    • (1992) Cell , vol.68 , pp. 157-166
    • Shirodkar, S.1    Ewen, M.2    Decaprio, J.A.3    Morgan, J.4    Livingston, D.M.5    Chittenden, T.6
  • 51
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • Singh, P., S.H. Wong, and W. Hong. 1994. Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J. 13: 3329-3338.
    • (1994) EMBO J. , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 52
    • 0028363519 scopus 로고
    • P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima, H. and T. Hunter. 1994. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78: 67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 53
    • 0028027308 scopus 로고
    • Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain
    • Treier, M., L.M. Staszewski, and D. Bohmann. 1994. Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain. Cell 78: 787-798.
    • (1994) Cell , vol.78 , pp. 787-798
    • Treier, M.1    Staszewski, L.M.2    Bohmann, D.3
  • 54
    • 0028902381 scopus 로고
    • Functional interaction between E2F-4 and p 130: Evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members
    • Vairo, G., D.M. Livingston, and D. Ginsberg. 1995. Functional interaction between E2F-4 and p 130: Evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes & Dev. 9: 869-881.
    • (1995) Genes & Dev. , vol.9 , pp. 869-881
    • Vairo, G.1    Livingston, D.M.2    Ginsberg, D.3
  • 55
    • 0026636908 scopus 로고
    • Retinoblastoma protein switches the E2F site from positive to negative element
    • Weintraub, S.J., C.A. Prater, and D.C. Dean. 1992. Retinoblastoma protein switches the E2F site from positive to negative element. Nature 358: 259-261.
    • (1992) Nature , vol.358 , pp. 259-261
    • Weintraub, S.J.1    Prater, C.A.2    Dean, D.C.3
  • 56
    • 0029043782 scopus 로고
    • Mechanisms of active transcriptional repression by the retinoblastoma protein
    • Weintraub, S.J., K.N.B. Chow, R.X. Luo, S.H. Zhang, S. He, and D.C. Dean. 1995. Mechanisms of active transcriptional repression by the retinoblastoma protein. Nature 375: 812-815.
    • (1995) Nature , vol.375 , pp. 812-815
    • Weintraub, S.J.1    Chow, K.N.B.2    Luo, R.X.3    Zhang, S.H.4    He, S.5    Dean, D.C.6
  • 57
    • 0023914010 scopus 로고
    • Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product
    • Whyte, P., K.J. Buchkovich, J.M. Horowitz, S.F. Friend, M. Ray buck, R.A. Weinberg, and E. Harlow. 1988. Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 334: 124-129.
    • (1988) Nature , vol.334 , pp. 124-129
    • Whyte, P.1    Buchkovich, K.J.2    Horowitz, J.M.3    Friend, S.F.4    Ray Buck, M.5    Weinberg, R.A.6    Harlow, E.7
  • 58
    • 0029915568 scopus 로고    scopus 로고
    • The human cytotnegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
    • Wiertz, E.J.H.J., T.R. Jones, L. Sun, M. Bogyo, H.J. Geuze, and H.L. Ploegh. 1996. The human cytotnegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 84: 769-779.
    • (1996) Cell , vol.84 , pp. 769-779
    • Wiertz, E.J.H.J.1    Jones, T.R.2    Sun, L.3    Bogyo, M.4    Geuze, H.J.5    Ploegh, H.L.6
  • 59
    • 0028222124 scopus 로고
    • P53 and E2F-1 cooperate to mediate apoptosis
    • Wu, X. and A.J. Levine. 1994. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. 91: 3602-3606.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 62
    • 0029026176 scopus 로고
    • The pRB-related protein p 107 contains two growth suppression domains: Independent interactions with E2F and cyclin/cdk complexes
    • Zhu, L., G. Enders, J.A. Lees, R.L. Beijersbergen, R. Bernards, and E. Harlow. 1995a. The pRB-related protein p 107 contains two growth suppression domains: Independent interactions with E2F and cyclin/cdk complexes. EMBO J. 14: 1904-1913.
    • (1995) EMBO J. , vol.14 , pp. 1904-1913
    • Zhu, L.1    Enders, G.2    Lees, J.A.3    Beijersbergen, R.L.4    Bernards, R.5    Harlow, E.6
  • 63
    • 0029054133 scopus 로고
    • Differential roles of two tandem E2F sites in the repression of the human p 107 promotor by retinoblastoma and p 107 proteins
    • Zhu, L., L. Zhu, E. Xie, and L.-S. Chang. 1995b. Differential roles of two tandem E2F sites in the repression of the human p 107 promotor by retinoblastoma and p 107 proteins. Mol. Cell. Biol. 15: 3552-3562.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3552-3562
    • Zhu, L.1    Zhu, L.2    Xie, E.3    Chang, L.-S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.