-
1
-
-
56949096401
-
Regulation by destruction: design of the sigmaE envelope stress response
-
Ades, S.E., Regulation by destruction: design of the sigmaE envelope stress response. Curr. Opin. Microbiol. 11 (2008), 535–540.
-
(2008)
Curr. Opin. Microbiol.
, vol.11
, pp. 535-540
-
-
Ades, S.E.1
-
2
-
-
0001598487
-
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase
-
Berlanga, J.J., Santoyo, J., De Haro, C., Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase. Eur. J. Biochem. 265 (1999), 754–762.
-
(1999)
Eur. J. Biochem.
, vol.265
, pp. 754-762
-
-
Berlanga, J.J.1
Santoyo, J.2
De Haro, C.3
-
3
-
-
84863495004
-
The role of oxidized phospholipids in atherosclerosis
-
Berliner, J.A., Leitinger, N., Tsimikas, S., The role of oxidized phospholipids in atherosclerosis. J. Lipid Res. 50:Suppl (2009), S207–S212.
-
(2009)
J. Lipid Res.
, vol.50
, pp. S207-S212
-
-
Berliner, J.A.1
Leitinger, N.2
Tsimikas, S.3
-
4
-
-
33645734929
-
Toll-dependent selection of microbial antigens for presentation by dendritic cells
-
Blander, J.M., Medzhitov, R., Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 440 (2006), 808–812.
-
(2006)
Nature
, vol.440
, pp. 808-812
-
-
Blander, J.M.1
Medzhitov, R.2
-
5
-
-
84857546470
-
Beyond pattern recognition: five immune checkpoints for scaling the microbial threat
-
Blander, J.M., Sander, L.E., Beyond pattern recognition: five immune checkpoints for scaling the microbial threat. Nat. Rev. Immunol. 12 (2012), 215–225.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 215-225
-
-
Blander, J.M.1
Sander, L.E.2
-
6
-
-
0037026527
-
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
-
Bochkov, V.N., Kadl, A., Huber, J., Gruber, F., Binder, B.R., Leitinger, N., Protective role of phospholipid oxidation products in endotoxin-induced tissue damage. Nature 419 (2002), 77–81.
-
(2002)
Nature
, vol.419
, pp. 77-81
-
-
Bochkov, V.N.1
Kadl, A.2
Huber, J.3
Gruber, F.4
Binder, B.R.5
Leitinger, N.6
-
7
-
-
84927639135
-
Innate immune pattern recognition: a cell biological perspective
-
Brubaker, S.W., Bonham, K.S., Zanoni, I., Kagan, J.C., Innate immune pattern recognition: a cell biological perspective. Annu. Rev. Immunol. 33 (2015), 257–290.
-
(2015)
Annu. Rev. Immunol.
, vol.33
, pp. 257-290
-
-
Brubaker, S.W.1
Bonham, K.S.2
Zanoni, I.3
Kagan, J.C.4
-
8
-
-
33745736151
-
Recognition and delivery of effector proteins into eukaryotic cells by bacterial secretion systems
-
Cambronne, E.D., Roy, C.R., Recognition and delivery of effector proteins into eukaryotic cells by bacterial secretion systems. Traffic 7 (2006), 929–939.
-
(2006)
Traffic
, vol.7
, pp. 929-939
-
-
Cambronne, E.D.1
Roy, C.R.2
-
9
-
-
0028935374
-
Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase
-
Chen, J.J., London, I.M., Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase. Trends Biochem. Sci. 20 (1995), 105–108.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 105-108
-
-
Chen, J.J.1
London, I.M.2
-
10
-
-
77954607064
-
A pathobiont of the microbiota balances host colonization and intestinal inflammation
-
Chow, J., Mazmanian, S.K., A pathobiont of the microbiota balances host colonization and intestinal inflammation. Cell Host Microbe 7 (2010), 265–276.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 265-276
-
-
Chow, J.1
Mazmanian, S.K.2
-
11
-
-
0037194733
-
Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane
-
Chow, A., Toomre, D., Garrett, W., Mellman, I., Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature 418 (2002), 988–994.
-
(2002)
Nature
, vol.418
, pp. 988-994
-
-
Chow, A.1
Toomre, D.2
Garrett, W.3
Mellman, I.4
-
12
-
-
84887557126
-
Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization
-
Chuenchor, W., Jin, T., Ravilious, G., Xiao, T.S., Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization. Curr. Opin. Immunol. 26 (2014), 14–20.
-
(2014)
Curr. Opin. Immunol.
, vol.26
, pp. 14-20
-
-
Chuenchor, W.1
Jin, T.2
Ravilious, G.3
Xiao, T.S.4
-
13
-
-
84962590036
-
Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA
-
Corrales, L., Woo, S.R., Williams, J.B., McWhirter, S.M., Dubensky, T.W. Jr., Gajewski, T.F., Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA. J. Immunol. 196 (2016), 3191–3198.
-
(2016)
J. Immunol.
, vol.196
, pp. 3191-3198
-
-
Corrales, L.1
Woo, S.R.2
Williams, J.B.3
McWhirter, S.M.4
Dubensky, T.W.5
Gajewski, T.F.6
-
14
-
-
77955056034
-
Manipulation of host membrane machinery by bacterial pathogens
-
Cossart, P., Roy, C.R., Manipulation of host membrane machinery by bacterial pathogens. Curr. Opin. Cell Biol. 22 (2010), 547–554.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 547-554
-
-
Cossart, P.1
Roy, C.R.2
-
15
-
-
84867647908
-
Rules of engagement: molecular insights from host-virus arms races
-
Daugherty, M.D., Malik, H.S., Rules of engagement: molecular insights from host-virus arms races. Annu. Rev. Genet. 46 (2012), 677–700.
-
(2012)
Annu. Rev. Genet.
, vol.46
, pp. 677-700
-
-
Daugherty, M.D.1
Malik, H.S.2
-
16
-
-
84962780206
-
Inflammasomes as polyvalent cell death platforms
-
de Vasconcelos, N.M., Van Opdenbosch, N., Lamkanfi, M., Inflammasomes as polyvalent cell death platforms. Cell. Mol. Life Sci. 73 (2016), 2335–2347.
-
(2016)
Cell. Mol. Life Sci.
, vol.73
, pp. 2335-2347
-
-
de Vasconcelos, N.M.1
Van Opdenbosch, N.2
Lamkanfi, M.3
-
17
-
-
84938390836
-
Molecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control
-
Diamond, M.S., Pierson, T.C., Molecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control. Cell 162 (2015), 488–492.
-
(2015)
Cell
, vol.162
, pp. 488-492
-
-
Diamond, M.S.1
Pierson, T.C.2
-
18
-
-
84978419608
-
Pore-forming activity and structural autoinhibition of the gasdermin family
-
Ding, J., Wang, K., Liu, W., She, Y., Sun, Q., Shi, J., Sun, H., Wang, D.C., Shao, F., Pore-forming activity and structural autoinhibition of the gasdermin family. Nature 535 (2016), 111–116.
-
(2016)
Nature
, vol.535
, pp. 111-116
-
-
Ding, J.1
Wang, K.2
Liu, W.3
She, Y.4
Sun, Q.5
Shi, J.6
Sun, H.7
Wang, D.C.8
Shao, F.9
-
19
-
-
84927724336
-
Initiation and perpetuation of NLRP3 inflammasome activation and assembly
-
Elliott, E.I., Sutterwala, F.S., Initiation and perpetuation of NLRP3 inflammasome activation and assembly. Immunol. Rev. 265 (2015), 35–52.
-
(2015)
Immunol. Rev.
, vol.265
, pp. 35-52
-
-
Elliott, E.I.1
Sutterwala, F.S.2
-
20
-
-
84983603118
-
Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion
-
Faber, F., Tran, L., Byndloss, M.X., Lopez, C.A., Velazquez, E.M., Kerrinnes, T., Nuccio, S.P., Wangdi, T., Fiehn, O., Tsolis, R.M., Bäumler, A.J., Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion. Nature 534 (2016), 697–699.
-
(2016)
Nature
, vol.534
, pp. 697-699
-
-
Faber, F.1
Tran, L.2
Byndloss, M.X.3
Lopez, C.A.4
Velazquez, E.M.5
Kerrinnes, T.6
Nuccio, S.P.7
Wangdi, T.8
Fiehn, O.9
Tsolis, R.M.10
Bäumler, A.J.11
-
21
-
-
62349112779
-
Oxidized phospholipids in control of inflammation and endothelial barrier
-
Fu, P., Birukov, K.G., Oxidized phospholipids in control of inflammation and endothelial barrier. Transl. Res. 153 (2009), 166–176.
-
(2009)
Transl. Res.
, vol.153
, pp. 166-176
-
-
Fu, P.1
Birukov, K.G.2
-
22
-
-
84962219519
-
Human Monocytes Engage an Alternative Inflammasome Pathway
-
Gaidt, M.M., Ebert, T.S., Chauhan, D., Schmidt, T., Schmid-Burgk, J.L., Rapino, F., Robertson, A.A., Cooper, M.A., Graf, T., Hornung, V., Human Monocytes Engage an Alternative Inflammasome Pathway. Immunity 44 (2016), 833–846.
-
(2016)
Immunity
, vol.44
, pp. 833-846
-
-
Gaidt, M.M.1
Ebert, T.S.2
Chauhan, D.3
Schmidt, T.4
Schmid-Burgk, J.L.5
Rapino, F.6
Robertson, A.A.7
Cooper, M.A.8
Graf, T.9
Hornung, V.10
-
23
-
-
67649400561
-
Common themes in the design and function of bacterial effectors
-
Galán, J.E., Common themes in the design and function of bacterial effectors. Cell Host Microbe 5 (2009), 571–579.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 571-579
-
-
Galán, J.E.1
-
24
-
-
33845627785
-
Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action
-
García, M.A., Gil, J., Ventoso, I., Guerra, S., Domingo, E., Rivas, C., Esteban, M., Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action. Microbiol. Mol. Biol. Rev. 70 (2006), 1032–1060.
-
(2006)
Microbiol. Mol. Biol. Rev.
, vol.70
, pp. 1032-1060
-
-
García, M.A.1
Gil, J.2
Ventoso, I.3
Guerra, S.4
Domingo, E.5
Rivas, C.6
Esteban, M.7
-
25
-
-
84905050462
-
Assembly and localization of Toll-like receptor signalling complexes
-
Gay, N.J., Symmons, M.F., Gangloff, M., Bryant, C.E., Assembly and localization of Toll-like receptor signalling complexes. Nat. Rev. Immunol. 14 (2014), 546–558.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 546-558
-
-
Gay, N.J.1
Symmons, M.F.2
Gangloff, M.3
Bryant, C.E.4
-
26
-
-
35348856289
-
Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells
-
Gioannini, T.L., Weiss, J.P., Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells. Immunol. Res. 39 (2007), 249–260.
-
(2007)
Immunol. Res.
, vol.39
, pp. 249-260
-
-
Gioannini, T.L.1
Weiss, J.P.2
-
27
-
-
1642529500
-
Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations
-
Gioannini, T.L., Teghanemt, A., Zhang, D., Coussens, N.P., Dockstader, W., Ramaswamy, S., Weiss, J.P., Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations. Proc. Natl. Acad. Sci. USA 101 (2004), 4186–4191.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4186-4191
-
-
Gioannini, T.L.1
Teghanemt, A.2
Zhang, D.3
Coussens, N.P.4
Dockstader, W.5
Ramaswamy, S.6
Weiss, J.P.7
-
28
-
-
33744791510
-
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
-
Gitlin, L., Barchet, W., Gilfillan, S., Cella, M., Beutler, B., Flavell, R.A., Diamond, M.S., Colonna, M., Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl. Acad. Sci. USA 103 (2006), 8459–8464.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8459-8464
-
-
Gitlin, L.1
Barchet, W.2
Gilfillan, S.3
Cella, M.4
Beutler, B.5
Flavell, R.A.6
Diamond, M.S.7
Colonna, M.8
-
29
-
-
78049271424
-
Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression
-
Goodall, J.C., Wu, C., Zhang, Y., McNeill, L., Ellis, L., Saudek, V., Gaston, J.S., Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression. Proc. Natl. Acad. Sci. USA 107 (2010), 17698–17703.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 17698-17703
-
-
Goodall, J.C.1
Wu, C.2
Zhang, Y.3
McNeill, L.4
Ellis, L.5
Saudek, V.6
Gaston, J.S.7
-
30
-
-
84940121945
-
Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome
-
Gray, E.E., Treuting, P.M., Woodward, J.J., Stetson, D.B., Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome. J. Immunol. 195 (2015), 1939–1943.
-
(2015)
J. Immunol.
, vol.195
, pp. 1939-1943
-
-
Gray, E.E.1
Treuting, P.M.2
Woodward, J.J.3
Stetson, D.B.4
-
31
-
-
33747036397
-
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
-
Gross, O., Gewies, A., Finger, K., Schäfer, M., Sparwasser, T., Peschel, C., Förster, I., Ruland, J., Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 442 (2006), 651–656.
-
(2006)
Nature
, vol.442
, pp. 651-656
-
-
Gross, O.1
Gewies, A.2
Finger, K.3
Schäfer, M.4
Sparwasser, T.5
Peschel, C.6
Förster, I.7
Ruland, J.8
-
32
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding, H.P., Zhang, Y., Zeng, H., Novoa, I., Lu, P.D., Calfon, M., Sadri, N., Yun, C., Popko, B., Paules, R., et al. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell 11 (2003), 619–633.
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
-
33
-
-
84863889691
-
The mechanism of eukaryotic translation initiation: new insights and challenges
-
Hinnebusch, A.G., Lorsch, J.R., The mechanism of eukaryotic translation initiation: new insights and challenges. Cold Spring Harb. Perspect. Biol., 4, 2012, a011544.
-
(2012)
Cold Spring Harb. Perspect. Biol.
, vol.4
, pp. a011544
-
-
Hinnebusch, A.G.1
Lorsch, J.R.2
-
34
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D.R., Latz, E., Fitzgerald, K.A., AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458 (2009), 514–518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
35
-
-
41949087380
-
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury
-
Imai, Y., Kuba, K., Neely, G.G., Yaghubian-Malhami, R., Perkmann, T., van Loo, G., Ermolaeva, M., Veldhuizen, R., Leung, Y.H., Wang, H., et al. Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell 133 (2008), 235–249.
-
(2008)
Cell
, vol.133
, pp. 235-249
-
-
Imai, Y.1
Kuba, K.2
Neely, G.G.3
Yaghubian-Malhami, R.4
Perkmann, T.5
van Loo, G.6
Ermolaeva, M.7
Veldhuizen, R.8
Leung, Y.H.9
Wang, H.10
-
36
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki, A., Medzhitov, R., Regulation of adaptive immunity by the innate immune system. Science 327 (2010), 291–295.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
37
-
-
0024955886
-
Approaching the asymptote? Evolution and revolution in immunology
-
Janeway, C.A. Jr., Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54 (1989), 1–13.
-
(1989)
Cold Spring Harb. Symp. Quant. Biol.
, vol.54
, pp. 1-13
-
-
Janeway, C.A.1
-
38
-
-
84859986329
-
Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor
-
Jin, T., Perry, A., Jiang, J., Smith, P., Curry, J.A., Unterholzner, L., Jiang, Z., Horvath, G., Rathinam, V.A., Johnstone, R.W., et al. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity 36 (2012), 561–571.
-
(2012)
Immunity
, vol.36
, pp. 561-571
-
-
Jin, T.1
Perry, A.2
Jiang, J.3
Smith, P.4
Curry, J.A.5
Unterholzner, L.6
Jiang, Z.7
Horvath, G.8
Rathinam, V.A.9
Johnstone, R.W.10
-
39
-
-
84988813074
-
Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis
-
Jorgensen, I., Zhang, Y., Krantz, B.A., Miao, E.A., Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis. J. Exp. Med. 213 (2016), 2113–2128.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 2113-2128
-
-
Jorgensen, I.1
Zhang, Y.2
Krantz, B.A.3
Miao, E.A.4
-
40
-
-
84870910920
-
Signaling organelles of the innate immune system
-
Kagan, J.C., Signaling organelles of the innate immune system. Cell 151 (2012), 1168–1178.
-
(2012)
Cell
, vol.151
, pp. 1168-1178
-
-
Kagan, J.C.1
-
41
-
-
84924794747
-
Emerging principles governing signal transduction by pattern-recognition receptors
-
Kagan, J.C., Barton, G.M., Emerging principles governing signal transduction by pattern-recognition receptors. Cold Spring Harb. Perspect. Biol., 7, 2014, a016253.
-
(2014)
Cold Spring Harb. Perspect. Biol.
, vol.7
, pp. a016253
-
-
Kagan, J.C.1
Barton, G.M.2
-
42
-
-
84922479840
-
SMOCs: supramolecular organizing centres that control innate immunity
-
Kagan, J.C., Magupalli, V.G., Wu, H., SMOCs: supramolecular organizing centres that control innate immunity. Nat. Rev. Immunol. 14 (2014), 821–826.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 821-826
-
-
Kagan, J.C.1
Magupalli, V.G.2
Wu, H.3
-
43
-
-
1642348822
-
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene
-
Kang, D.C., Gopalkrishnan, R.V., Lin, L., Randolph, A., Valerie, K., Pestka, S., Fisher, P.B., Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene. Oncogene 23 (2004), 1789–1800.
-
(2004)
Oncogene
, vol.23
, pp. 1789-1800
-
-
Kang, D.C.1
Gopalkrishnan, R.V.2
Lin, L.3
Randolph, A.4
Valerie, K.5
Pestka, S.6
Fisher, P.B.7
-
44
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., Uematsu, S., Jung, A., Kawai, T., Ishii, K.J., et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441 (2006), 101–105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
Matsui, K.6
Uematsu, S.7
Jung, A.8
Kawai, T.9
Ishii, K.J.10
-
45
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki, N., Warming, S., Lamkanfi, M., Vande Walle, L., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heldens, S., et al. Non-canonical inflammasome activation targets caspase-11. Nature 479 (2011), 117–121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
-
46
-
-
84942856523
-
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
-
Kayagaki, N., Stowe, I.B., Lee, B.L., O'Rourke, K., Anderson, K., Warming, S., Cuellar, T., Haley, B., Roose-Girma, M., Phung, Q.T., et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 526 (2015), 666–671.
-
(2015)
Nature
, vol.526
, pp. 666-671
-
-
Kayagaki, N.1
Stowe, I.B.2
Lee, B.L.3
O'Rourke, K.4
Anderson, K.5
Warming, S.6
Cuellar, T.7
Haley, B.8
Roose-Girma, M.9
Phung, Q.T.10
-
47
-
-
84878592773
-
Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity
-
Kranzusch, P.J., Lee, A.S., Berger, J.M., Doudna, J.A., Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity. Cell Rep. 3 (2013), 1362–1368.
-
(2013)
Cell Rep.
, vol.3
, pp. 1362-1368
-
-
Kranzusch, P.J.1
Lee, A.S.2
Berger, J.M.3
Doudna, J.A.4
-
48
-
-
0034960171
-
Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation
-
Krishnamoorthy, T., Pavitt, G.D., Zhang, F., Dever, T.E., Hinnebusch, A.G., Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation. Mol. Cell. Biol. 21 (2001), 5018–5030.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5018-5030
-
-
Krishnamoorthy, T.1
Pavitt, G.D.2
Zhang, F.3
Dever, T.E.4
Hinnebusch, A.G.5
-
49
-
-
38949091132
-
Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen
-
Leber, J.H., Crimmins, G.T., Raghavan, S., Meyer-Morse, N.P., Cox, J.S., Portnoy, D.A., Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen. PLoS Pathog., 4, 2008, e6.
-
(2008)
PLoS Pathog.
, vol.4
, pp. e6
-
-
Leber, J.H.1
Crimmins, G.T.2
Raghavan, S.3
Meyer-Morse, N.P.4
Cox, J.S.5
Portnoy, D.A.6
-
50
-
-
33947667884
-
Innate control of adaptive immunity: dendritic cells and beyond
-
Lee, H.K., Iwasaki, A., Innate control of adaptive immunity: dendritic cells and beyond. Semin. Immunol. 19 (2007), 48–55.
-
(2007)
Semin. Immunol.
, vol.19
, pp. 48-55
-
-
Lee, H.K.1
Iwasaki, A.2
-
51
-
-
34249026701
-
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
-
LeibundGut-Landmann, S., Gross, O., Robinson, M.J., Osorio, F., Slack, E.C., Tsoni, S.V., Schweighoffer, E., Tybulewicz, V., Brown, G.D., Ruland, J., Reis e Sousa, C., Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 8 (2007), 630–638.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 630-638
-
-
LeibundGut-Landmann, S.1
Gross, O.2
Robinson, M.J.3
Osorio, F.4
Slack, E.C.5
Tsoni, S.V.6
Schweighoffer, E.7
Tybulewicz, V.8
Brown, G.D.9
Ruland, J.10
Reis e Sousa, C.11
-
52
-
-
0017890248
-
Regulation of protein synthesis: activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2
-
Levin, D., London, I.M., Regulation of protein synthesis: activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2. Proc. Natl. Acad. Sci. USA 75 (1978), 1121–1125.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 1121-1125
-
-
Levin, D.1
London, I.M.2
-
53
-
-
77953714711
-
Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
-
Lin, S.C., Lo, Y.C., Wu, H., Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 465 (2010), 885–890.
-
(2010)
Nature
, vol.465
, pp. 885-890
-
-
Lin, S.C.1
Lo, Y.C.2
Wu, H.3
-
54
-
-
84924778328
-
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
-
Liu, S., Cai, X., Wu, J., Cong, Q., Chen, X., Li, T., Du, F., Ren, J., Wu, Y.T., Grishin, N.V., Chen, Z.J., Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation. Science, 347, 2015, aaa2630.
-
(2015)
Science
, vol.347
, pp. aaa2630
-
-
Liu, S.1
Cai, X.2
Wu, J.3
Cong, Q.4
Chen, X.5
Li, T.6
Du, F.7
Ren, J.8
Wu, Y.T.9
Grishin, N.V.10
Chen, Z.J.11
-
55
-
-
84978374487
-
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
-
Liu, X., Zhang, Z., Ruan, J., Pan, Y., Magupalli, V.G., Wu, H., Lieberman, J., Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature 535 (2016), 153–158.
-
(2016)
Nature
, vol.535
, pp. 153-158
-
-
Liu, X.1
Zhang, Z.2
Ruan, J.3
Pan, Y.4
Magupalli, V.G.5
Wu, H.6
Lieberman, J.7
-
56
-
-
84998611004
-
Nucleic acid-sensing TLRs: trafficking and regulation
-
Majer, O., Liu, B., Barton, G.M., Nucleic acid-sensing TLRs: trafficking and regulation. Curr. Opin. Immunol. 44 (2016), 26–33.
-
(2016)
Curr. Opin. Immunol.
, vol.44
, pp. 26-33
-
-
Majer, O.1
Liu, B.2
Barton, G.M.3
-
57
-
-
84927732725
-
Regulation of inflammasome activation
-
Man, S.M., Kanneganti, T.D., Regulation of inflammasome activation. Immunol. Rev. 265 (2015), 6–21.
-
(2015)
Immunol. Rev.
, vol.265
, pp. 6-21
-
-
Man, S.M.1
Kanneganti, T.D.2
-
58
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S., Weiss, D.S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W.P., Weinrauch, Y., Monack, D.M., Dixit, V.M., Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440 (2006), 228–232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
59
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon, F., Chen, X., Lee, A.H., Glimcher, L.H., TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat. Immunol. 11 (2010), 411–418.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
Glimcher, L.H.4
-
60
-
-
66949122854
-
Approaching the asymptote: 20 years later
-
Medzhitov, R., Approaching the asymptote: 20 years later. Immunity 30 (2009), 766–775.
-
(2009)
Immunity
, vol.30
, pp. 766-775
-
-
Medzhitov, R.1
-
61
-
-
0347717903
-
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
-
Mempel, T.R., Henrickson, S.E., Von Andrian, U.H., T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427 (2004), 154–159.
-
(2004)
Nature
, vol.427
, pp. 154-159
-
-
Mempel, T.R.1
Henrickson, S.E.2
Von Andrian, U.H.3
-
62
-
-
80053487700
-
Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions
-
Meng, J., Gong, M., Björkbacka, H., Golenbock, D.T., Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions. J. Immunol. 187 (2011), 3683–3693.
-
(2011)
J. Immunol.
, vol.187
, pp. 3683-3693
-
-
Meng, J.1
Gong, M.2
Björkbacka, H.3
Golenbock, D.T.4
-
63
-
-
0034459468
-
Upstream open reading frames as regulators of mRNA translation
-
Morris, D.R., Geballe, A.P., Upstream open reading frames as regulators of mRNA translation. Mol. Cell. Biol. 20 (2000), 8635–8642.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8635-8642
-
-
Morris, D.R.1
Geballe, A.P.2
-
64
-
-
69949161905
-
An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4
-
Motshwene, P.G., Moncrieffe, M.C., Grossmann, J.G., Kao, C., Ayaluru, M., Sandercock, A.M., Robinson, C.V., Latz, E., Gay, N.J., An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4. J. Biol. Chem. 284 (2009), 25404–25411.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 25404-25411
-
-
Motshwene, P.G.1
Moncrieffe, M.C.2
Grossmann, J.G.3
Kao, C.4
Ayaluru, M.5
Sandercock, A.M.6
Robinson, C.V.7
Latz, E.8
Gay, N.J.9
-
65
-
-
0141566327
-
Regulation of eIF2alpha phosphorylation by different functions that act during discrete phases in the herpes simplex virus type 1 life cycle
-
Mulvey, M., Poppers, J., Sternberg, D., Mohr, I., Regulation of eIF2alpha phosphorylation by different functions that act during discrete phases in the herpes simplex virus type 1 life cycle. J. Virol. 77 (2003), 10917–10928.
-
(2003)
J. Virol.
, vol.77
, pp. 10917-10928
-
-
Mulvey, M.1
Poppers, J.2
Sternberg, D.3
Mohr, I.4
-
67
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami, T., Ockinger, J., Yu, J., Byles, V., McColl, A., Hofer, A.M., Horng, T., Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc. Natl. Acad. Sci. USA 109 (2012), 11282–11287.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
Horng, T.7
-
68
-
-
84927661602
-
Inflammasome-independent regulation of IL-1-family cytokines
-
Netea, M.G., van de Veerdonk, F.L., van der Meer, J.W., Dinarello, C.A., Joosten, L.A., Inflammasome-independent regulation of IL-1-family cytokines. Annu. Rev. Immunol. 33 (2015), 49–77.
-
(2015)
Annu. Rev. Immunol.
, vol.33
, pp. 49-77
-
-
Netea, M.G.1
van de Veerdonk, F.L.2
van der Meer, J.W.3
Dinarello, C.A.4
Joosten, L.A.5
-
69
-
-
84861474688
-
Signaling in innate immunity and inflammation
-
Newton, K., Dixit, V.M., Signaling in innate immunity and inflammation. Cold Spring Harb. Perspect. Biol., 4, 2012, a006049.
-
(2012)
Cold Spring Harb. Perspect. Biol.
, vol.4
, pp. a006049
-
-
Newton, K.1
Dixit, V.M.2
-
70
-
-
84960399221
-
Immunometabolism governs dendritic cell and macrophage function
-
O'Neill, L.A., Pearce, E.J., Immunometabolism governs dendritic cell and macrophage function. J. Exp. Med. 213 (2016), 15–23.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 15-23
-
-
O'Neill, L.A.1
Pearce, E.J.2
-
71
-
-
84904680881
-
Diverse intracellular pathogens activate type III interferon expression from peroxisomes
-
Odendall, C., Dixit, E., Stavru, F., Bierne, H., Franz, K.M., Durbin, A.F., Boulant, S., Gehrke, L., Cossart, P., Kagan, J.C., Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat. Immunol. 15 (2014), 717–726.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 717-726
-
-
Odendall, C.1
Dixit, E.2
Stavru, F.3
Bierne, H.4
Franz, K.M.5
Durbin, A.F.6
Boulant, S.7
Gehrke, L.8
Cossart, P.9
Kagan, J.C.10
-
72
-
-
84951320286
-
Tissue biology perspective on macrophages
-
Okabe, Y., Medzhitov, R., Tissue biology perspective on macrophages. Nat. Immunol. 17 (2016), 9–17.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 9-17
-
-
Okabe, Y.1
Medzhitov, R.2
-
73
-
-
84907515304
-
Cellular sensing of viral DNA and viral evasion mechanisms
-
Orzalli, M.H., Knipe, D.M., Cellular sensing of viral DNA and viral evasion mechanisms. Annu. Rev. Microbiol. 68 (2014), 477–492.
-
(2014)
Annu. Rev. Microbiol.
, vol.68
, pp. 477-492
-
-
Orzalli, M.H.1
Knipe, D.M.2
-
74
-
-
84941755669
-
Microbial sensing by Toll-like receptors and intracellular nucleic acid sensors
-
Pandey, S., Kawai, T., Akira, S., Microbial sensing by Toll-like receptors and intracellular nucleic acid sensors. Cold Spring Harb. Perspect. Biol., 7, 2014, a016246.
-
(2014)
Cold Spring Harb. Perspect. Biol.
, vol.7
, pp. a016246
-
-
Pandey, S.1
Kawai, T.2
Akira, S.3
-
75
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
Park, B.S., Song, D.H., Kim, H.M., Choi, B.S., Lee, H., Lee, J.O., The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 458 (2009), 1191–1195.
-
(2009)
Nature
, vol.458
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
Choi, B.S.4
Lee, H.5
Lee, J.O.6
-
76
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun, P., Deane, J.A., Difilippantonio, M.J., Tarasenko, T., Satterthwaite, A.B., Bolland, S., Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 312 (2006), 1669–1672.
-
(2006)
Science
, vol.312
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.A.2
Difilippantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
Bolland, S.6
-
77
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
-
Poltorak, A., He, X., Smirnova, I., Liu, M.Y., Van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282 (1998), 2085–2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
78
-
-
84969257253
-
NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo
-
Rauch, I., Tenthorey, J.L., Nichols, R.D., Al Moussawi, K., Kang, J.J., Kang, C., Kazmierczak, B.I., Vance, R.E., NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo. J. Exp. Med. 213 (2016), 657–665.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 657-665
-
-
Rauch, I.1
Tenthorey, J.L.2
Nichols, R.D.3
Al Moussawi, K.4
Kang, J.J.5
Kang, C.6
Kazmierczak, B.I.7
Vance, R.E.8
-
79
-
-
0034775153
-
Toll-like receptors control activation of adaptive immune responses
-
Schnare, M., Barton, G.M., Holt, A.C., Takeda, K., Akira, S., Medzhitov, R., Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2 (2001), 947–950.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 947-950
-
-
Schnare, M.1
Barton, G.M.2
Holt, A.C.3
Takeda, K.4
Akira, S.5
Medzhitov, R.6
-
80
-
-
77950362382
-
The inflammasomes
-
Schroder, K., Tschopp, J., The inflammasomes. Cell 140 (2010), 821–832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
81
-
-
77954856078
-
Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity
-
Schulz, O., Pichlmair, A., Rehwinkel, J., Rogers, N.C., Scheuner, D., Kato, H., Takeuchi, O., Akira, S., Kaufman, R.J., Reis e Sousa, C., Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity. Cell Host Microbe 7 (2010), 354–361.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 354-361
-
-
Schulz, O.1
Pichlmair, A.2
Rehwinkel, J.3
Rogers, N.C.4
Scheuner, D.5
Kato, H.6
Takeuchi, O.7
Akira, S.8
Kaufman, R.J.9
Reis e Sousa, C.10
-
82
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., Zhuang, Y., Cai, T., Wang, F., Shao, F., Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526 (2015), 660–665.
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
Zhao, Y.2
Wang, K.3
Shi, X.4
Wang, Y.5
Huang, H.6
Zhuang, Y.7
Cai, T.8
Wang, F.9
Shao, F.10
-
83
-
-
0033809383
-
The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus
-
Stojdl, D.F., Abraham, N., Knowles, S., Marius, R., Brasey, A., Lichty, B.D., Brown, E.G., Sonenberg, N., Bell, J.C., The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus. J. Virol. 74 (2000), 9580–9585.
-
(2000)
J. Virol.
, vol.74
, pp. 9580-9585
-
-
Stojdl, D.F.1
Abraham, N.2
Knowles, S.3
Marius, R.4
Brasey, A.5
Lichty, B.D.6
Brown, E.G.7
Sonenberg, N.8
Bell, J.C.9
-
84
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun, L., Wu, J., Du, F., Chen, X., Chen, Z.J., Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339 (2013), 786–791.
-
(2013)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
85
-
-
84902970152
-
Mechanism of NLRP3 inflammasome activation
-
Sutterwala, F.S., Haasken, S., Cassel, S.L., Mechanism of NLRP3 inflammasome activation. Ann. N Y Acad. Sci. 1319 (2014), 82–95.
-
(2014)
Ann. N Y Acad. Sci.
, vol.1319
, pp. 82-95
-
-
Sutterwala, F.S.1
Haasken, S.2
Cassel, S.L.3
-
86
-
-
0024741693
-
Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes
-
Tilney, L.G., Portnoy, D.A., Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes. J. Cell Biol. 109 (1989), 1597–1608.
-
(1989)
J. Cell Biol.
, vol.109
, pp. 1597-1608
-
-
Tilney, L.G.1
Portnoy, D.A.2
-
87
-
-
20444458715
-
Functions of the respiratory burst oxidase in biotic interactions, abiotic stress and development
-
Torres, M.A., Dangl, J.L., Functions of the respiratory burst oxidase in biotic interactions, abiotic stress and development. Curr. Opin. Plant Biol. 8 (2005), 397–403.
-
(2005)
Curr. Opin. Plant Biol.
, vol.8
, pp. 397-403
-
-
Torres, M.A.1
Dangl, J.L.2
-
88
-
-
67651091732
-
Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system
-
Vance, R.E., Isberg, R.R., Portnoy, D.A., Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system. Cell Host Microbe 6 (2009), 10–21.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 10-21
-
-
Vance, R.E.1
Isberg, R.R.2
Portnoy, D.A.3
-
89
-
-
84945542875
-
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes
-
Viganò, E., Diamond, C.E., Spreafico, R., Balachander, A., Sobota, R.M., Mortellaro, A., Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes. Nat. Commun., 6, 2015, 8761.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8761
-
-
Viganò, E.1
Diamond, C.E.2
Spreafico, R.3
Balachander, A.4
Sobota, R.M.5
Mortellaro, A.6
-
90
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter, P., Ron, D., The unfolded protein response: from stress pathway to homeostatic regulation. Science 334 (2011), 1081–1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
91
-
-
77957157893
-
Gut inflammation provides a respiratory electron acceptor for Salmonella
-
Winter, S.E., Thiennimitr, P., Winter, M.G., Butler, B.P., Huseby, D.L., Crawford, R.W., Russell, J.M., Bevins, C.L., Adams, L.G., Tsolis, R.M., et al. Gut inflammation provides a respiratory electron acceptor for Salmonella. Nature 467 (2010), 426–429.
-
(2010)
Nature
, vol.467
, pp. 426-429
-
-
Winter, S.E.1
Thiennimitr, P.2
Winter, M.G.3
Butler, B.P.4
Huseby, D.L.5
Crawford, R.W.6
Russell, J.M.7
Bevins, C.L.8
Adams, L.G.9
Tsolis, R.M.10
-
92
-
-
84978483985
-
Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan
-
Wolf, A.J., Reyes, C.N., Liang, W., Becker, C., Shimada, K., Wheeler, M.L., Cho, H.C., Popescu, N.I., Coggeshall, K.M., Arditi, M., Underhill, D.M., Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell 166 (2016), 624–636.
-
(2016)
Cell
, vol.166
, pp. 624-636
-
-
Wolf, A.J.1
Reyes, C.N.2
Liang, W.3
Becker, C.4
Shimada, K.5
Wheeler, M.L.6
Cho, H.C.7
Popescu, N.I.8
Coggeshall, K.M.9
Arditi, M.10
Underhill, D.M.11
-
93
-
-
84856487878
-
Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B
-
Woo, C.W., Kutzler, L., Kimball, S.R., Tabas, I., Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B. Nat. Cell Biol. 14 (2012), 192–200.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 192-200
-
-
Woo, C.W.1
Kutzler, L.2
Kimball, S.R.3
Tabas, I.4
-
94
-
-
84873724533
-
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
-
Wu, J., Sun, L., Chen, X., Du, F., Shi, H., Chen, C., Chen, Z.J., Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339 (2013), 826–830.
-
(2013)
Science
, vol.339
, pp. 826-830
-
-
Wu, J.1
Sun, L.2
Chen, X.3
Du, F.4
Shi, H.5
Chen, C.6
Chen, Z.J.7
-
95
-
-
70449092388
-
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
-
Yanai, H., Ban, T., Wang, Z., Choi, M.K., Kawamura, T., Negishi, H., Nakasato, M., Lu, Y., Hangai, S., Koshiba, R., et al. HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 462 (2009), 99–103.
-
(2009)
Nature
, vol.462
, pp. 99-103
-
-
Yanai, H.1
Ban, T.2
Wang, Z.3
Choi, M.K.4
Kawamura, T.5
Negishi, H.6
Nakasato, M.7
Lu, Y.8
Hangai, S.9
Koshiba, R.10
-
96
-
-
84928928403
-
ATP-dependent effector-like functions of RIG-I-like receptors
-
Yao, H., Dittmann, M., Peisley, A., Hoffmann, H.H., Gilmore, R.H., Schmidt, T., Schmid-Burgk, J.L., Hornung, V., Rice, C.M., Hur, S., ATP-dependent effector-like functions of RIG-I-like receptors. Mol. Cell 58 (2015), 541–548.
-
(2015)
Mol. Cell
, vol.58
, pp. 541-548
-
-
Yao, H.1
Dittmann, M.2
Peisley, A.3
Hoffmann, H.H.4
Gilmore, R.H.5
Schmidt, T.6
Schmid-Burgk, J.L.7
Hornung, V.8
Rice, C.M.9
Hur, S.10
-
97
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., Miyagishi, M., Taira, K., Akira, S., Fujita, T., The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5 (2004), 730–737.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
98
-
-
84964434465
-
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
-
Zanoni, I., Tan, Y., Di Gioia, M., Broggi, A., Ruan, J., Shi, J., Donado, C.A., Shao, F., Wu, H., Springstead, J.R., Kagan, J.C., An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science 352 (2016), 1232–1236.
-
(2016)
Science
, vol.352
, pp. 1232-1236
-
-
Zanoni, I.1
Tan, Y.2
Di Gioia, M.3
Broggi, A.4
Ruan, J.5
Shi, J.6
Donado, C.A.7
Shao, F.8
Wu, H.9
Springstead, J.R.10
Kagan, J.C.11
-
99
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao, Y., Yang, J., Shi, J., Gong, Y.N., Lu, Q., Xu, H., Liu, L., Shao, F., The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477 (2011), 596–600.
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.N.4
Lu, Q.5
Xu, H.6
Liu, L.7
Shao, F.8
-
100
-
-
84969218921
-
Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice
-
Zhao, Y., Shi, J., Shi, X., Wang, Y., Wang, F., Shao, F., Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice. J. Exp. Med. 213 (2016), 647–656.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 647-656
-
-
Zhao, Y.1
Shi, J.2
Shi, X.3
Wang, Y.4
Wang, F.5
Shao, F.6
|