Diverse intracellular pathogens activate type III interferon expression from peroxisomes

Nature Immunology

Volumn 15, Issue 8, 2014, Pages 717-726

  Odendall, Charlotte ^a   Dixit, Evelyn ^a   Stavru, Fabrizia ^b   Bierne, Helene ^b,f   Franz, Kate M ^a   Durbin, Ann Fiegen ^c,d   Boulant, Steeve ^e   Gehrke, Lee ^c,d   Cossart, Pascale ^b   Kagan, Jonathan C ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b INSERM   (France)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f UMR1319 MICALIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCEOSOME; INTERFERON; INTERFERON RECEPTOR; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 3; INTERFERON TYPE III; NEUTRALIZING ANTIBODY; PEGINTERFERON LAMBDA; RIG 1 LIKE RECEPTOR; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BIOGENESIS; CELL DIFFERENTIATION; CELL ORGANELLE; CELL POPULATION; GENE EXPRESSION; GENOTYPE; HOST PATHOGEN INTERACTION; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTESTINE EPITHELIUM CELL; LIVER CELL; LOSS OF FUNCTION MUTATION; MITOCHONDRION; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PEROXISOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REOVIRUS INFECTION; REPORTER GENE; RNA INTERFERENCE; SUPERNATANT; UNTRANSLATED REGION; UPREGULATION; ZELLWEGER SYNDROME;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CELL DIFFERENTIATION; CELL LINE; CYCLOHEXANES; DEAD-BOX RNA HELICASES; ENZYME INHIBITORS; HUMANS; IMMUNITY, INNATE; INTERFERONS; INTESTINAL MUCOSA; JANUS KINASE 2; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEROXISOMES; PYRIDONES; REOVIRIDAE; REOVIRIDAE INFECTIONS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TYRPHOSTINS; VIDARABINE;

EID: 84904680881     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2915     Document Type: Article

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