Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

Science

Volumn 312, Issue 5780, 2006, Pages 1669-1672

  Pisitkun, Prapaporn ^a   Deane, Jonathan A ^a   Difilippantonio, Michael J ^b   Tarasenko, Tatyana ^a   Satterthwaite, Anne B ^c   Bolland, Silvia ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; CHARACTERIZATION; CHROMOSOMES; DISEASES; GENES; SYSTEMS ANALYSIS;

NUCLEOLAR ANTIGENS; POLYGENIC DISEASE; PSEUDOAUTOSOMAL REGION; SYSTEMIC AUTOIMMUNITY;

RNA;

ANTINUCLEAR ANTIBODY; AUTOANTIGEN; CD69 ANTIGEN; COMPLEMENTARY DNA; FC RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; RNA; TOLL LIKE RECEPTOR 7;

ANTIGEN; CHROMOSOME; DISEASE; GENE; GENE FLOW; IMMUNE RESPONSE; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; B LYMPHOCYTE; BTK GENE; CHROMATIN; CONTROLLED STUDY; GENE; GENE DUPLICATION; GENE LOCUS; GLOMERULONEPHRITIS; IMMUNOFLUORESCENCE; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; NUCLEOLUS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; TLR7 GENE; Y CHROMOSOME; YAA GENE;

AMINOQUINOLINES; ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODY SPECIFICITY; AUTOIMMUNITY; B-LYMPHOCYTES; CELL NUCLEOLUS; FEMALE; GENE DOSAGE; GENE DUPLICATION; IN SITU HYBRIDIZATION, FLUORESCENCE; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, B-CELL; RNA; TOLL-LIKE RECEPTOR 7; X CHROMOSOME; Y CHROMOSOME;

EID: 33745168605     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1124978     Document Type: Article

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