An Oligomeric Signaling Platform formed by the toll-like receptor signal transducers MyD88 and IRAK-4

Journal of Biological Chemistry

Volumn 284, Issue 37, 2009, Pages 25404-25411

  Motshwene, Precious G ^a   Moncrieffe, Martin C ^a   Grossmann, J Günter ^b   Kao, Cheng ^c   Ayaluru, Murali ^c   Sandercock, Alan M ^a   Robinson, Carol V ^a   Latz, Eicke ^d   Gay, Nicholas J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c TEXAS A AND M UNIVERSITY   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; DEATH DOMAIN; DEATH-INDUCING SIGNALING COMPLEXES; IN-VIVO; INNATE IMMUNE RESPONSE; LIPID RAFT; PROTEIN KINASE; RECEPTOR COMPLEX; TOLL-LIKE RECEPTORS;

INTERFERONS; SIGNAL TRANSDUCTION; STOICHIOMETRY;

SIGNALING;

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MYELOID DIFFERENTIATION FACTOR 88; OLIGOMER; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIPID RAFT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STOICHIOMETRY;

ANTIGENS, CD95; CELL LINE; CROSS-LINKING REAGENTS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MASS SPECTROMETRY; MEMBRANE MICRODOMAINS; MODELS, BIOLOGICAL; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN STRUCTURE, TERTIARY; SCATTERING, RADIATION; SIGNAL TRANSDUCTION; ULTRACENTRIFUGATION; X-RAYS;

VERTEBRATA;

EID: 69949161905     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.022392     Document Type: Article

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