Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 12, 2004, Pages 4186-4191

  Gioannini, Theresa L ^a,b   Teghanemt, Athmane ^a   Zhang, DeSheng ^a   Coussens, Nathan P ^a   Dockstader, Wendie ^a   Ramaswamy, S ^a   Weiss, Jerrold P ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; ENDOTOXIN; ENDOTOXIN PROTEIN MD2 COMPLEX; LIPOPOLYSACCHARIDE BINDING PROTEIN; PROTEIN; PROTEIN MD 2; RECOMBINANT PROTEIN; RECOMBINANT PROTEIN MD 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ARTICLE; CELL ACTIVATION; CELL STRAIN; CELL STRAIN HEK; COMPLEX FORMATION; EMBRYO CELL; GRAM NEGATIVE BACTERIUM; HOST CELL; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PURIFICATION; STOICHIOMETRY;

ANIMALS; ANTIGENS, CD14; ANTIGENS, SURFACE; ENDOTOXINS; HUMANS; IMMUNE SYSTEM; INSECTS; LYMPHOCYTE ANTIGEN 96; MEMBRANE GLYCOPROTEINS; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 1642529500     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0306906101     Document Type: Article

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