Tight binding of the phosphorylated α at subunit of initiation factor 2 (eIF2α) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation

Molecular and Cellular Biology

Volumn 21, Issue 15, 2001, Pages 5018-5030

  Krishnamoorthy, T ^a   Pavitt, G D ^a   Zhang, F ^a   Dever, T E ^a   Hinnebusch, A G ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; INITIATION FACTOR 2; METHIONINE TRANSFER RNA; SERINE;

ALPHA CHAIN; ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; GENE MUTATION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RIBOSOME SUBUNIT; TRANSLATION INITIATION; YEAST;

BINDING SITES; CATALYSIS; EUKARYOTIC INITIATION FACTOR-2B; GENOTYPE; GLUTATHIONE TRANSFERASE; MODELS, BIOLOGICAL; MUTATION; NICKEL; PEPTIDE INITIATION FACTORS; PHOSPHORYLATION; PLASMIDS; PROKARYOTIC INITIATION FACTOR-2; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RNA, TRANSFER, MET;

EID: 0034960171     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.15.5018-5030.2001     Document Type: Article

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