Biomimetic Thioesters as Probes for Enzymatic Assembly Lines: Synthesis, Applications, and Challenges

Cell Chemical Biology

Volumn 23, Issue 10, 2016, Pages 1179-1192

  Franke, Jakob ^a   Hertweck, Christian ^a,b  

^a HANS KNÖLL INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Coenzyme A; Fatty acid synthase; N Acetylcysteamine; Non ribosomal peptide synthetase; Polyketide synthase; SNAC; Thiotemplates

Indexed keywords

N ACETYLCYSTEAMINE THIOESTER; PANTETHEINE PHOSPHATE; POLYKETIDE; THIOESTER; UNCLASSIFIED DRUG; COENZYME A; FATTY ACID SYNTHASE; MERCAPTAMINE; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDE SYNTHASE; POLYKETIDE SYNTHASE;

BIOMIMETICS; ENZYME MECHANISM; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; REVIEW; SYNTHESIS; ACETYLATION; ANALOGS AND DERIVATIVES; BACTERIUM; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; FUNGUS; METABOLISM;

ACETYLATION; BACTERIA; BIOMIMETICS; BIOSYNTHETIC PATHWAYS; COENZYME A; CYSTEAMINE; FATTY ACID SYNTHASES; FUNGI; PEPTIDE SYNTHASES; POLYKETIDE SYNTHASES;

EID: 84992188157     PISSN: 24519456     EISSN: 24519448     Source Type: Journal    
DOI: 10.1016/j.chembiol.2016.08.014     Document Type: Review

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