Structural insights into the mechanism and inhibition of the β-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa

Journal of Molecular Biology

Volumn 425, Issue 2, 2013, Pages 365-377

  Moynié, Lucile ^a   Leckie, Stuart M ^a   McMahon, Stephen A ^a   Duthie, Fraser G ^a   Koehnke, Alessa ^a   Taylor, James W ^a   Alphey, Magnus S ^a   Brenk, Ruth ^b   Smith, Andrew D ^a   Naismith, James H ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

bacterial virulence; fatty acid biosynthesis; hydroxydecanoyl ACP dehydratase

Indexed keywords

3 HYDROXYDECANOYL N ACETYLCYSTEAMINE; BACTERIAL PROTEIN; BETA HYDROXYACYL ACYL CARRIER PROTEIN; FABA PROTEIN; FABZ PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME INHIBITION; FATTY ACID SYNTHESIS; ISOMERIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN POLYMERIZATION; PROTEIN STRUCTURE; PSEUDOMONAS AERUGINOSA;

BACTERIA (MICROORGANISMS); EUKARYOTA; NEGIBACTERIA; PROKARYOTA; PSEUDOMONAS AERUGINOSA;

EID: 84872111212     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.11.017     Document Type: Article

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