Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein

Biochemistry

Volumn 44, Issue 46, 2005, Pages 15414-15421

  Arthur, Christopher J ^a   Szafranska, Anna ^a   Evans, Simon E ^a   Findlow, Stuart C ^b   Burston, Steven G ^c   Owen, Philip ^d   Clark Lewis, Ian ^d   Simpson, Thomas J ^a   Crosby, John ^a   Crump, Matthew P ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; BIOSYNTHESIS; ESCHERICHIA COLI; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS;

CIRCULAR DICHROISM (CD); POLYKETIDE BIOSYNTHESIS; POLYKETIDE SYNTHASE (PKS); SELF-MALONYLATION;

ENZYMES;

ACYL CARRIER PROTEIN; ACYLTRANSFERASE; CHAPERONIN; MALONYL COENZYME A:HOLO ACYL CARRIER PROTEIN TRANSACYLASE; POLYKETIDE SYNTHASE; POLYKETIDE SYNTHASE II; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CIRCULAR DICHROISM; ENZYME ACTIVITY; ESCHERICHIA COLI; IN VITRO STUDY; MALONYLATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID STATE; STREPTOMYCES COELICOLOR; WILD TYPE;

ACYL CARRIER PROTEIN; ACYL-CARRIER PROTEIN S-MALONYLTRANSFERASE; APOPROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MALONATES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLYKETIDE SYNTHASES; PROTEIN FOLDING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STREPTOMYCES COELICOLOR;

ESCHERICHIA COLI; STREPTOMYCES COELICOLOR;

EID: 27944505997     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051499i     Document Type: Article

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