Structural rearrangements of a polyketide synthase module during its catalytic cycle

Nature

Volumn 510, Issue 7506, 2014, Pages 560-564

  Whicher, Jonathan R ^a   Dutta, Somnath ^a   Hansen, Douglas A ^a   Hale, Wendi A ^a   Chemler, Joseph A ^a   Dosey, Annie M ^a   Narayan, Alison R H ^a   Håkansson, Kristina ^a   Sherman, David H ^a,b   Smith, Janet L ^a,b   Skiniotis, Georgios ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; ACYLTRANSFERASE; PIKROMYCIN; POLYKETIDE; POLYKETIDE SYNTHASE;

CATALYSIS; ENZYME ACTIVITY; MICROBIAL COMMUNITY; PROTEIN; REACTION KINETICS;

ARTICLE; CRYOELECTRON MICROSCOPY; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; STREPTOMYCES VENEZUELAE;

ACYL CARRIER PROTEIN; ACYLTRANSFERASES; ALCOHOL OXIDOREDUCTASES; BACTERIAL PROTEINS; BIOCATALYSIS; CATALYTIC DOMAIN; CRYOELECTRON MICROSCOPY; MACROLIDES; MODELS, MOLECULAR; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; STREPTOMYCES;

EID: 84903481589     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13409     Document Type: Article

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