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Volumn 54, Issue 52, 1998, Pages 15937-15958

Biosynthetic incorporation of advanced precursors into dehydrocurvularin, a polyketide phytotoxin from Alternaria cinerariae

Author keywords

[No Author keywords available]

Indexed keywords

DEHYDROCURVULARIN 1; PLANT TOXIN; UNCLASSIFIED DRUG;

EID: 0032564631     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(98)01003-5     Document Type: Article
Times cited : (35)

References (90)
  • 27
  • 46
    • 0002938935 scopus 로고    scopus 로고
    • Leeper, F. J., Vederas, J. C., Eds.; Springer-Verlag: Berlin
    • 20. For reviews of isotopic methods to study secondary metabolism see: (a) Simpson, T. J. In Biosynthesis: Polyketides and Vitamins, Topics in Current Chemistry; Leeper, F. J., Vederas, J. C., Eds.; Springer-Verlag: Berlin, 1998, pp. 1-48.
    • (1998) Biosynthesis: Polyketides and Vitamins, Topics in Current Chemistry , pp. 1-48
    • Simpson, T.J.1
  • 67
    • 0010330554 scopus 로고
    • 33. Although 25 has not been directly demonstrated to inhibit β-oxidation enzymes, other alkynoic acids such as 4-pentynoic acid are effective at stopping precursor degradation by this route: see ref. 11b and Cane, D. E.; Prabhakaran, P. C.; Tan, W.; Ott, W. R. Tetrahedron Lett. 1991, 32, 5475-5460.
    • (1991) Tetrahedron Lett. , vol.32 , pp. 5475-15460
    • Cane, D.E.1    Prabhakaran, P.C.2    Tan, W.3    Ott, W.R.4
  • 72
    • 85038544319 scopus 로고    scopus 로고
    • note
    • 35. Under typical fermentation conditions A. cinerariae can produce 200 mg of 1 and 50 mg of 3 per litre of culture broth.
  • 83
    • 85038542046 scopus 로고    scopus 로고
    • note
    • 40. Reduction of metyrapone has been observed with S. cinnamonensis during studies on monensin biosynthesis, but in this case deoxymonensins A and B accumulated. See ref. 39d.
  • 85
    • 85038542990 scopus 로고    scopus 로고
    • note
    • (b) Hypoglycin 24 was a generous gift by Prof. E. A. Kean (University of the West Indies, Kingston, Jamaica).
  • 86
    • 85038552828 scopus 로고    scopus 로고
    • note
    • 33,34
  • 87
    • 85038551504 scopus 로고    scopus 로고
    • note
    • (d) Ancymidol 28 and metyrapone 29 are now available from Sigma Chemical Co.
  • 90
    • 0019425248 scopus 로고
    • 44. Mori, K. Tetrahedron 1981, 37, 1341-1342.
    • (1981) Tetrahedron , vol.37 , pp. 1341-1342
    • Mori, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.