메뉴 건너뛰기




Volumn 31, Issue , 2016, Pages 80-92

Nutritional strategies to optimise cognitive function in the aging brain

Author keywords

Aging; Cognition; Geometric framework; Intermittent fasting; Macronutrients

Indexed keywords

AMINO ACID; CARBOHYDRATE; FAT; PROTEIN;

EID: 84988432005     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2016.06.006     Document Type: Review
Times cited : (84)

References (189)
  • 2
    • 0031590708 scopus 로고    scopus 로고
    • Changes in the ageing brain in health and disease
    • Anderton, B.H., Changes in the ageing brain in health and disease. Philos. Trans. R. Soc. B 352 (1997), 1781–1792.
    • (1997) Philos. Trans. R. Soc. B , vol.352 , pp. 1781-1792
    • Anderton, B.H.1
  • 3
    • 0036178612 scopus 로고    scopus 로고
    • Ageing of the brain
    • Anderton, B.H., Ageing of the brain. Mech. Ageing Dev. 123 (2002), 811–817.
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 811-817
    • Anderton, B.H.1
  • 4
    • 84890331040 scopus 로고    scopus 로고
    • Metformin: do we finally have an anti-aging drug?
    • Anisimov, V.N., Metformin: do we finally have an anti-aging drug?. ABBV Cell Cycle 12 (2013), 3483–3489.
    • (2013) ABBV Cell Cycle , vol.12 , pp. 3483-3489
    • Anisimov, V.N.1
  • 5
    • 84879779694 scopus 로고    scopus 로고
    • Development of a new method for assessing global risk of Alzheimer's disease for use in population health approaches to prevention
    • Anstey, K.J., Cherbuin, N., Herath, P.M., Development of a new method for assessing global risk of Alzheimer's disease for use in population health approaches to prevention. Prev. Sci. 14 (2013), 411–421.
    • (2013) Prev. Sci. , vol.14 , pp. 411-421
    • Anstey, K.J.1    Cherbuin, N.2    Herath, P.M.3
  • 7
    • 84988415728 scopus 로고    scopus 로고
    • Australian Institute of Health and Welfare, 2012. Dementia in Australia. Cat. no. AGE 70. Canberra : AIHW.
    • Australian Institute of Health and Welfare, 2012. Dementia in Australia. Cat. no. AGE 70. Canberra : AIHW.
  • 8
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban, R.S., Nemoto, S., Finkel, T., Mitochondria, oxidants, and aging. Cell 120 (2005), 483–495.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 9
    • 84914165449 scopus 로고    scopus 로고
    • Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls
    • Bannister, C.A., Holden, S.E., Jenkins-Jones, S., Morgan, C.L., Halcox, J.P., Schernthaner, G., Mukherjee, J., Currie, C.J., Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls. Diabetes Obes. Metab. 16 (2014), 1165–1173.
    • (2014) Diabetes Obes. Metab. , vol.16 , pp. 1165-1173
    • Bannister, C.A.1    Holden, S.E.2    Jenkins-Jones, S.3    Morgan, C.L.4    Halcox, J.P.5    Schernthaner, G.6    Mukherjee, J.7    Currie, C.J.8
  • 10
    • 84908879458 scopus 로고    scopus 로고
    • Consideration of nutrient levels in studies of cognitive decline
    • Barnes, J.L., Tian, M., Edens, N.K., Morris, M.C., Consideration of nutrient levels in studies of cognitive decline. Nutr. Rev. 72 (2014), 707–719.
    • (2014) Nutr. Rev. , vol.72 , pp. 707-719
    • Barnes, J.L.1    Tian, M.2    Edens, N.K.3    Morris, M.C.4
  • 12
    • 0034893715 scopus 로고    scopus 로고
    • The role of AGEs in aging: causation or correlation
    • Baynes, J.W., The role of AGEs in aging: causation or correlation. Exp. Gerontol. 36 (2001), 1527–1537.
    • (2001) Exp. Gerontol. , vol.36 , pp. 1527-1537
    • Baynes, J.W.1
  • 13
    • 84940887392 scopus 로고    scopus 로고
    • Diet-induced cognitive deficits: the role of fat and sugar, potential mechanisms and nutritional interventions
    • Beilharz, J.E., Maniam, J., Morris, M.J., Diet-induced cognitive deficits: the role of fat and sugar, potential mechanisms and nutritional interventions. Nutrients 7 (2015), 6719–6738.
    • (2015) Nutrients , vol.7 , pp. 6719-6738
    • Beilharz, J.E.1    Maniam, J.2    Morris, M.J.3
  • 15
    • 84921682801 scopus 로고    scopus 로고
    • Longitudinal inflammation, cognitive decline, and Alzheimer's disease: a mini-review
    • Bettcher, B.M., Kramer, J.H., Longitudinal inflammation, cognitive decline, and Alzheimer's disease: a mini-review. Clin. Pharmacol. Ther. 96 (2014), 464–469.
    • (2014) Clin. Pharmacol. Ther. , vol.96 , pp. 464-469
    • Bettcher, B.M.1    Kramer, J.H.2
  • 16
    • 33845670719 scopus 로고    scopus 로고
    • Nitric oxide regulates mitochondrial oxidative stress protection via the transcriptional coactivator PGC-1 alpha
    • Borniquel, S., Valle, I., Cadenas, S., Lamas, S., Monsalve, M., Nitric oxide regulates mitochondrial oxidative stress protection via the transcriptional coactivator PGC-1 alpha. FASEB J. 20 (2006), 1889–1891.
    • (2006) FASEB J. , vol.20 , pp. 1889-1891
    • Borniquel, S.1    Valle, I.2    Cadenas, S.3    Lamas, S.4    Monsalve, M.5
  • 17
    • 33751570170 scopus 로고    scopus 로고
    • Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 2: macronutrients
    • Bourre, J.M., Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 2: macronutrients. J. Nutr. Health Aging 10 (2006), 386–399.
    • (2006) J. Nutr. Health Aging , vol.10 , pp. 386-399
    • Bourre, J.M.1
  • 19
    • 84867716731 scopus 로고    scopus 로고
    • Making Alzheimer's and dementia research fit for populations
    • Brayne, C., Davis, D., Making Alzheimer's and dementia research fit for populations. Lancet 380 (2012), 1441–1443.
    • (2012) Lancet , vol.380 , pp. 1441-1443
    • Brayne, C.1    Davis, D.2
  • 20
    • 77049202076 scopus 로고
    • Organization of the cerebral cortex. 3. A study of aging in the human cerebral cortex
    • Brody, H., Organization of the cerebral cortex. 3. A study of aging in the human cerebral cortex. J. Comp. Neurol. 102 (1955), 511–556.
    • (1955) J. Comp. Neurol. , vol.102 , pp. 511-556
    • Brody, H.1
  • 22
    • 0032925851 scopus 로고    scopus 로고
    • Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
    • Bruce-Keller, A.J., Umberger, G., McFall, R., Mattson, M.P., Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann. Neurol. 45 (1999), 8–15.
    • (1999) Ann. Neurol. , vol.45 , pp. 8-15
    • Bruce-Keller, A.J.1    Umberger, G.2    McFall, R.3    Mattson, M.P.4
  • 23
    • 84901745843 scopus 로고    scopus 로고
    • Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature
    • Caccamo, A., De Pinto, V., Messina, A., Branca, C., Oddo, S., Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature. J. Neurosci. 34 (2014), 7988–7998.
    • (2014) J. Neurosci. , vol.34 , pp. 7988-7998
    • Caccamo, A.1    De Pinto, V.2    Messina, A.3    Branca, C.4    Oddo, S.5
  • 25
  • 26
    • 84857921494 scopus 로고    scopus 로고
    • Calorie restriction increases cerebral mitochondrial respiratory capacity in a NO-mediated mechanism: imact on neuronal survival
    • Cerqueira, F.M., Cunha, F.M., Laurindo, F.R.M., Kowaltowski, A.J., Calorie restriction increases cerebral mitochondrial respiratory capacity in a NO-mediated mechanism: imact on neuronal survival. Free Radic. Biol. Med. 52 (2012), 1236–1241.
    • (2012) Free Radic. Biol. Med. , vol.52 , pp. 1236-1241
    • Cerqueira, F.M.1    Cunha, F.M.2    Laurindo, F.R.M.3    Kowaltowski, A.J.4
  • 29
    • 84943267892 scopus 로고    scopus 로고
    • The cognitive architecture of spatial navigation: hippocampal and striatal contributions
    • Chersi, F., Burgess, N., The cognitive architecture of spatial navigation: hippocampal and striatal contributions. Neuron 88 (2015), 64–77.
    • (2015) Neuron , vol.88 , pp. 64-77
    • Chersi, F.1    Burgess, N.2
  • 33
    • 78650928762 scopus 로고    scopus 로고
    • Intrinsic programs regulating dendrites and synapses in the upper layer neurons of the cortex
    • Cubelos, B., Nieto, M., Intrinsic programs regulating dendrites and synapses in the upper layer neurons of the cortex. Commun. Integr. Biol. 3 (2010), 483–486.
    • (2010) Commun. Integr. Biol. , vol.3 , pp. 483-486
    • Cubelos, B.1    Nieto, M.2
  • 34
    • 56449129140 scopus 로고    scopus 로고
    • Low-carbohydrate weight-loss diets. Effects on cognition and mood
    • 32
    • D'Anci, K.E., Watts, K.L., Kanarek, R.B., Taylor, H.A., Low-carbohydrate weight-loss diets. Effects on cognition and mood. Appetite, 2009, 96–103 32.
    • (2009) Appetite , pp. 96-103
    • D'Anci, K.E.1    Watts, K.L.2    Kanarek, R.B.3    Taylor, H.A.4
  • 35
    • 84871379266 scopus 로고    scopus 로고
    • The Effects of SIRT1 on Alzheimer's Disease Models
    • Donmez, G., The Effects of SIRT1 on Alzheimer's Disease Models. Int. J. Alzheimers Dis., 2012, 509529.
    • (2012) Int. J. Alzheimers Dis. , pp. 509529
    • Donmez, G.1
  • 36
    • 79551633658 scopus 로고    scopus 로고
    • Cognitive performances are selectively enhanced during chronic caloric restriction or resveratrol supplementation in a primate
    • Dal-Pan, A., Pifferi, F., Marchal, J., Picq, J.L., Aujard, F., Cognitive performances are selectively enhanced during chronic caloric restriction or resveratrol supplementation in a primate. PLoS One, 6, 2011, e16581.
    • (2011) PLoS One , vol.6 , pp. e16581
    • Dal-Pan, A.1    Pifferi, F.2    Marchal, J.3    Picq, J.L.4    Aujard, F.5
  • 38
    • 84899639780 scopus 로고    scopus 로고
    • The amyloid hypothesis, time to move on: amyloid is the downstream result, not cause, of Alzheimer's disease
    • Drachman, D.A., The amyloid hypothesis, time to move on: amyloid is the downstream result, not cause, of Alzheimer's disease. Alzheimers Dement. 10 (2014), 372–380.
    • (2014) Alzheimers Dement. , vol.10 , pp. 372-380
    • Drachman, D.A.1
  • 39
    • 0033566286 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
    • Duan, W., Mattson, M.P., Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J. Neurosci. Res. 57 (1999), 195–206.
    • (1999) J. Neurosci. Res. , vol.57 , pp. 195-206
    • Duan, W.1    Mattson, M.P.2
  • 40
    • 84947867105 scopus 로고    scopus 로고
    • Role of mTOR in glioblastoma
    • Duzgun, Z., Eroglu, Z., Biray Avci, C., Role of mTOR in glioblastoma. Gene 575 (2015), 187–190.
    • (2015) Gene , vol.575 , pp. 187-190
    • Duzgun, Z.1    Eroglu, Z.2    Biray Avci, C.3
  • 41
    • 84938587122 scopus 로고    scopus 로고
    • Calorie restriction, ageing and longevity
    • (14-14)
    • Everitt, A., Calorie restriction, ageing and longevity. Aust. J. Ageing, 29, 2010 (14-14).
    • (2010) Aust. J. Ageing , vol.29
    • Everitt, A.1
  • 42
    • 70449435581 scopus 로고    scopus 로고
    • Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease
    • Ferrer, I., Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease. J. Bioenerg. Biomembr. 41 (2009), 425–431.
    • (2009) J. Bioenerg. Biomembr. , vol.41 , pp. 425-431
    • Ferrer, I.1
  • 43
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel, T., Holbrook, N.J., Oxidants, oxidative stress and the biology of ageing. Nature 408 (2000), 239–247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 44
    • 84925852614 scopus 로고    scopus 로고
    • Promoting health and longevity through diet: from model organisms to humans
    • Fontana, L., Partridge, L., Promoting health and longevity through diet: from model organisms to humans. Cell 161 (2015), 106–118.
    • (2015) Cell , vol.161 , pp. 106-118
    • Fontana, L.1    Partridge, L.2
  • 46
    • 84900988267 scopus 로고    scopus 로고
    • Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
    • Franceschi, C., Campisi, J., Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J. Gerontol. A. Biol. Sci. Med. Sci. 69:Suppl. 1 (2014), S4–9.
    • (2014) J. Gerontol. A. Biol. Sci. Med. Sci. , vol.69 , pp. S4-9
    • Franceschi, C.1    Campisi, J.2
  • 47
    • 84882449801 scopus 로고    scopus 로고
    • Brain response to calorie restriction
    • Fusco, S., Pani, G., Brain response to calorie restriction. Cell Mol. Life Sci. 70 (2013), 3157–3170.
    • (2013) Cell Mol. Life Sci. , vol.70 , pp. 3157-3170
    • Fusco, S.1    Pani, G.2
  • 48
    • 84922800283 scopus 로고    scopus 로고
    • Age-related metabolic fatigue during low glucose conditions in rat hippocampus
    • Galeffi, F., Shetty, P.K., Sadgrove, M.P., Turner, D.A., Age-related metabolic fatigue during low glucose conditions in rat hippocampus. Neurobiol. Aging 36 (2015), 982–992.
    • (2015) Neurobiol. Aging , vol.36 , pp. 982-992
    • Galeffi, F.1    Shetty, P.K.2    Sadgrove, M.P.3    Turner, D.A.4
  • 49
    • 84933679949 scopus 로고    scopus 로고
    • Habitual fat intake predicts memory function in younger women
    • Gibson, E.L., Barr, S., Jeanes, Y.M., Habitual fat intake predicts memory function in younger women. Front. Hum. Neurosci., 7, 2013, 838.
    • (2013) Front. Hum. Neurosci. , vol.7 , pp. 838
    • Gibson, E.L.1    Barr, S.2    Jeanes, Y.M.3
  • 50
    • 84947592469 scopus 로고    scopus 로고
    • Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury
    • Godar, R.J., Ma, X., Liu, H., Murphy, J.T., Weinheimer, C.J., Kovacs, A., Crosby, S.D., Saftig, P., Diwan, A., Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury. Autophagy 11 (2015), 1537–1560.
    • (2015) Autophagy , vol.11 , pp. 1537-1560
    • Godar, R.J.1    Ma, X.2    Liu, H.3    Murphy, J.T.4    Weinheimer, C.J.5    Kovacs, A.6    Crosby, S.D.7    Saftig, P.8    Diwan, A.9
  • 51
    • 28444471173 scopus 로고    scopus 로고
    • Glucose and age-related changes in memory
    • Gold, P.E., Glucose and age-related changes in memory. Neurobiol. Aging 26:Suppl. 1 (2005), 60–64.
    • (2005) Neurobiol. Aging , vol.26 , pp. 60-64
    • Gold, P.E.1
  • 52
    • 45749151055 scopus 로고    scopus 로고
    • Brain foods: the effects of nutrients on brain function
    • Gomez-Pinilla, F., Brain foods: the effects of nutrients on brain function. Nat. Rev. Neurosci. 9 (2008), 568–578.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 568-578
    • Gomez-Pinilla, F.1
  • 53
    • 84901331100 scopus 로고    scopus 로고
    • Resveratrol and Alzheimer's disease: message in a bottle on red wine and cognition
    • Granzotto, A., Zatta, P., Resveratrol and Alzheimer's disease: message in a bottle on red wine and cognition. Front. Aging. Neurosci., 6, 2014, 95.
    • (2014) Front. Aging. Neurosci. , vol.6 , pp. 95
    • Granzotto, A.1    Zatta, P.2
  • 55
    • 0037165871 scopus 로고    scopus 로고
    • Age-related and laminar-specific dendritic changes in the medial frontal cortex of the rat
    • Grill, J.D., Riddle, D.R., Age-related and laminar-specific dendritic changes in the medial frontal cortex of the rat. Brain Res. 937 (2002), 8–21.
    • (2002) Brain Res. , vol.937 , pp. 8-21
    • Grill, J.D.1    Riddle, D.R.2
  • 57
    • 33947264635 scopus 로고    scopus 로고
    • Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
    • Halagappa, V.K., Guo, Z., Pearson, M., Matsuoka, Y., Cutler, R.G., Laferla, F.M., Mattson, M.P., Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol. Dis. 26 (2007), 212–220.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 212-220
    • Halagappa, V.K.1    Guo, Z.2    Pearson, M.3    Matsuoka, Y.4    Cutler, R.G.5    Laferla, F.M.6    Mattson, M.P.7
  • 58
    • 0026082894 scopus 로고
    • Region-specific stability of dendritic extent in normal human aging andregression in Alzheimers-disease. 1. Ca1 of Hippocampus
    • Hanks, S.D., Flood, D.G., Region-specific stability of dendritic extent in normal human aging andregression in Alzheimers-disease. 1. Ca1 of Hippocampus. Brain Res. 540 (1991), 63–82.
    • (1991) Brain Res. , vol.540 , pp. 63-82
    • Hanks, S.D.1    Flood, D.G.2
  • 59
    • 84930659887 scopus 로고    scopus 로고
    • A randomised controlled trial investigating the effects of Mediterranean diet and aerobic exercise on cognition in cognitively healthy older people living independently within aged care facilities: the Lifestyle Intervention in Independent Living Aged Care (LIILAC) study protocol [ACTRN12614001133628]
    • Hardman, R.J., Kennedy, G., Macpherson, H., Scholey, A.B., Pipingas, A., A randomised controlled trial investigating the effects of Mediterranean diet and aerobic exercise on cognition in cognitively healthy older people living independently within aged care facilities: the Lifestyle Intervention in Independent Living Aged Care (LIILAC) study protocol [ACTRN12614001133628]. Nutr. J., 14, 2015, 53.
    • (2015) Nutr. J. , vol.14 , pp. 53
    • Hardman, R.J.1    Kennedy, G.2    Macpherson, H.3    Scholey, A.B.4    Pipingas, A.5
  • 63
    • 84867346421 scopus 로고    scopus 로고
    • Association of shorter leukocyte telomere repeat length with dementia and mortality
    • Honig, L.S., Kang, M.S., Schupf, N., Lee, J.H., Mayeux, R., Association of shorter leukocyte telomere repeat length with dementia and mortality. Arch. Neurol. 69 (2012), 1332–1339.
    • (2012) Arch. Neurol. , vol.69 , pp. 1332-1339
    • Honig, L.S.1    Kang, M.S.2    Schupf, N.3    Lee, J.H.4    Mayeux, R.5
  • 65
    • 33845938278 scopus 로고    scopus 로고
    • Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging
    • Hyun, D.H., Emerson, S.S., Jo, D.G., Mattson, M.P., de Cabo, R., Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 19908–19912.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 19908-19912
    • Hyun, D.H.1    Emerson, S.S.2    Jo, D.G.3    Mattson, M.P.4    de Cabo, R.5
  • 66
    • 79956192192 scopus 로고    scopus 로고
    • Effect of a high protein meat diet on muscle and cognitive functions: a randomised controlled dietary intervention trial in healthy men
    • Jakobsen, L.H., Kondrup, J., Zellner, M., Tetens, I., Roth, E., Effect of a high protein meat diet on muscle and cognitive functions: a randomised controlled dietary intervention trial in healthy men. Clin. Nutr. 30 (2011), 303–311.
    • (2011) Clin. Nutr. , vol.30 , pp. 303-311
    • Jakobsen, L.H.1    Kondrup, J.2    Zellner, M.3    Tetens, I.4    Roth, E.5
  • 67
    • 84988375742 scopus 로고    scopus 로고
    • Japan Ministry of Health, Labor and Welfare Statistics and Information Division. Japan National Health Statistics for 2000. Tokyo, Japan: Japan Ministry of Health, Labor and Welfare.
    • Japan Ministry of Health, Labor and Welfare Statistics and Information Division. Japan National Health Statistics for 2000. Tokyo, Japan: Japan Ministry of Health, Labor and Welfare, 2002.
    • (2002)
  • 68
    • 84969884761 scopus 로고    scopus 로고
    • Nrf2-a therapeutic target for the treatment of neurodegenerative diseases
    • Johnson, D.A., Johnson, J.A., Nrf2-a therapeutic target for the treatment of neurodegenerative diseases. Free Radic. Biol. Med. 88 (2015), 253–267.
    • (2015) Free Radic. Biol. Med. , vol.88 , pp. 253-267
    • Johnson, D.A.1    Johnson, J.A.2
  • 70
    • 84856363036 scopus 로고    scopus 로고
    • Acute ingestion of different macronutrients differentially enhances aspects of memory and attention in healthy young adults
    • Jones, E.K., Sunram-Lea, S.I., Wesnes, K.A., Acute ingestion of different macronutrients differentially enhances aspects of memory and attention in healthy young adults. Biol. Psychol. 89 (2012), 477–486.
    • (2012) Biol. Psychol. , vol.89 , pp. 477-486
    • Jones, E.K.1    Sunram-Lea, S.I.2    Wesnes, K.A.3
  • 71
    • 61349185119 scopus 로고    scopus 로고
    • Caloric restriction does not offset age-associated changes in the biophysical properties of motoneurons
    • Kalmar, J.M., Button, D.C., Gardiner, K., Cahill, F., Gardiner, P.F., Caloric restriction does not offset age-associated changes in the biophysical properties of motoneurons. J. Neurophysiol. 101 (2009), 548–557.
    • (2009) J. Neurophysiol. , vol.101 , pp. 548-557
    • Kalmar, J.M.1    Button, D.C.2    Gardiner, K.3    Cahill, F.4    Gardiner, P.F.5
  • 73
    • 84938100054 scopus 로고    scopus 로고
    • Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus
    • Kaptan, Z., Akgun-Dar, K., Kapucu, A., Dedeakayogullari, H., Batu, S., Uzum, G., Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus. Brain Res. 1618 (2015), 194–204.
    • (2015) Brain Res. , vol.1618 , pp. 194-204
    • Kaptan, Z.1    Akgun-Dar, K.2    Kapucu, A.3    Dedeakayogullari, H.4    Batu, S.5    Uzum, G.6
  • 76
    • 84887478616 scopus 로고    scopus 로고
    • The finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): study design and progress
    • Kivipelto, M., Solomon, A., Ahtiluoto, S., Ngandu, T., Lehtisalo, J., Antikainen, R., Soininen, H., The finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): study design and progress. Alzheimers Dement. 9 (2013), 657–665.
    • (2013) Alzheimers Dement. , vol.9 , pp. 657-665
    • Kivipelto, M.1    Solomon, A.2    Ahtiluoto, S.3    Ngandu, T.4    Lehtisalo, J.5    Antikainen, R.6    Soininen, H.7
  • 77
    • 0037312020 scopus 로고    scopus 로고
    • How does calorie restriction work?
    • Koubova, J., Guarente, L., How does calorie restriction work?. Genes Dev. 17 (2003), 313–321.
    • (2003) Genes Dev. , vol.17 , pp. 313-321
    • Koubova, J.1    Guarente, L.2
  • 79
    • 85005781374 scopus 로고    scopus 로고
    • The airbag problem-a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer's disease
    • Krstic, D., Knuesel, I., The airbag problem-a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer's disease. Acta Neuropathol. Commun., 1, 2013, 62.
    • (2013) Acta Neuropathol. Commun. , vol.1 , pp. 62
    • Krstic, D.1    Knuesel, I.2
  • 81
    • 84945162443 scopus 로고    scopus 로고
    • Carbohydrate ingestion but not mouth rinse maintains sustained attention when fasted
    • Kumar, N., Wheaton, L.A., Snow, T.K., Millard-Stafford, M., Carbohydrate ingestion but not mouth rinse maintains sustained attention when fasted. Physiol. Behav. 153 (2015), 33–39.
    • (2015) Physiol. Behav. , vol.153 , pp. 33-39
    • Kumar, N.1    Wheaton, L.A.2    Snow, T.K.3    Millard-Stafford, M.4
  • 82
    • 79955125211 scopus 로고    scopus 로고
    • Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome
    • Labbé, A., Garand, C., Cogger, V.C., Paquet, E.R., Desbiens, M., Le Couteur, D.G., Lebel, M., Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome. J. Gerontol. A: Med. Sci. Biol. Sci. 66 (2011), 264–278.
    • (2011) J. Gerontol. A: Med. Sci. Biol. Sci. , vol.66 , pp. 264-278
    • Labbé, A.1    Garand, C.2    Cogger, V.C.3    Paquet, E.R.4    Desbiens, M.5    Le Couteur, D.G.6    Lebel, M.7
  • 83
    • 84883510170 scopus 로고    scopus 로고
    • The role of sirtuins in Alzheimer's disease
    • Lalla, R., Donmez, G., The role of sirtuins in Alzheimer's disease. Front. Aging Neurosci., 5, 2013, 16.
    • (2013) Front. Aging Neurosci. , vol.5 , pp. 16
    • Lalla, R.1    Donmez, G.2
  • 88
    • 84887645055 scopus 로고    scopus 로고
    • Biomedicine. A putative antiaging drug takes a step from mice to men
    • Leslie, M., Biomedicine. A putative antiaging drug takes a step from mice to men. Science, 342, 2013, 789.
    • (2013) Science , vol.342 , pp. 789
    • Leslie, M.1
  • 89
    • 84859043569 scopus 로고    scopus 로고
    • Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice
    • Li, J., Deng, J., Sheng, W., Zuo, Z., Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice. Pharmacol. Biochem. Behav. 101 (2012), 564–574.
    • (2012) Pharmacol. Biochem. Behav. , vol.101 , pp. 564-574
    • Li, J.1    Deng, J.2    Sheng, W.3    Zuo, Z.4
  • 90
    • 84938986138 scopus 로고    scopus 로고
    • Overexpression of SIRT1 induced by resveratrol and inhibitor of miR-204 suppresses activation and proliferation of microglia
    • Li, L., Sun, Q., Li, Y., Yang, Y., Chang, T., Man, M., Zheng, L., Overexpression of SIRT1 induced by resveratrol and inhibitor of miR-204 suppresses activation and proliferation of microglia. J. Mol. Neurosci. 56 (2015), 858–867.
    • (2015) J. Mol. Neurosci. , vol.56 , pp. 858-867
    • Li, L.1    Sun, Q.2    Li, Y.3    Yang, Y.4    Chang, T.5    Man, M.6    Zheng, L.7
  • 91
    • 33751011308 scopus 로고    scopus 로고
    • PGC-1 alpha: a key regulator of energy metabolism
    • Liang, H.Y., Ward, W.F., PGC-1 alpha: a key regulator of energy metabolism. Adv. Physiol. Educ. 30 (2006), 145–151.
    • (2006) Adv. Physiol. Educ. , vol.30 , pp. 145-151
    • Liang, H.Y.1    Ward, W.F.2
  • 93
    • 83755186591 scopus 로고    scopus 로고
    • Intermittent supplementation with rapamycin as a dietary restriction mimetic
    • Longo, V.D., Fontana, L., Intermittent supplementation with rapamycin as a dietary restriction mimetic. Aging (Albany NY) 3 (2011), 1039–1040.
    • (2011) Aging (Albany NY) , vol.3 , pp. 1039-1040
    • Longo, V.D.1    Fontana, L.2
  • 95
    • 60749090581 scopus 로고    scopus 로고
    • The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies
    • Maalouf, M., Rho, J.M., Mattson, M.P., The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain. Res. Rev. 59 (2009), 293–315.
    • (2009) Brain. Res. Rev. , vol.59 , pp. 293-315
    • Maalouf, M.1    Rho, J.M.2    Mattson, M.P.3
  • 96
    • 33646227422 scopus 로고    scopus 로고
    • Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats
    • Mager, D.E., Wan, R., Brown, M., Cheng, A., Wareski, P., Abernethy, D.R., Mattson, M.P., Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats. FASEB J. 20 (2006), 631–637.
    • (2006) FASEB J. , vol.20 , pp. 631-637
    • Mager, D.E.1    Wan, R.2    Brown, M.3    Cheng, A.4    Wareski, P.5    Abernethy, D.R.6    Mattson, M.P.7
  • 98
    • 84999488593 scopus 로고    scopus 로고
    • Targeting molecules to medicine with mTOR, autophagy, and neurodegenerative disorders
    • Maiese, K., Targeting molecules to medicine with mTOR, autophagy, and neurodegenerative disorders. Br. J. Clin. Pharmacol., 2015, 10.1111/bcp.12804.
    • (2015) Br. J. Clin. Pharmacol.
    • Maiese, K.1
  • 99
    • 84930069493 scopus 로고    scopus 로고
    • Nutritional habits and cognitive performance of older adults
    • Mallidou, A., Cartie, M., Nutritional habits and cognitive performance of older adults. Nurs. Manag. (Harrow) 22 (2015), 27–34.
    • (2015) Nurs. Manag. (Harrow) , vol.22 , pp. 27-34
    • Mallidou, A.1    Cartie, M.2
  • 100
    • 84893021363 scopus 로고    scopus 로고
    • BDNF mediates adaptive brain and body responses to energetic challenges
    • Marosi, K., Mattson, M.P., BDNF mediates adaptive brain and body responses to energetic challenges. Trends. Endocrinol. Metab. 25 (2014), 89–98.
    • (2014) Trends. Endocrinol. Metab. , vol.25 , pp. 89-98
    • Marosi, K.1    Mattson, M.P.2
  • 101
    • 34250681755 scopus 로고    scopus 로고
    • Examination of cognitive function during six months of calorie restriction: results of a randomized controlled trial
    • Martin, C.K., Anton, S.D., Han, H., York-Crowe, E., Redman, L.M., Ravussin, E., Williamson, D.A., Examination of cognitive function during six months of calorie restriction: results of a randomized controlled trial. Rejuvenation Res. 10 (2007), 179–190.
    • (2007) Rejuvenation Res. , vol.10 , pp. 179-190
    • Martin, C.K.1    Anton, S.D.2    Han, H.3    York-Crowe, E.4    Redman, L.M.5    Ravussin, E.6    Williamson, D.A.7
  • 103
    • 65549089108 scopus 로고    scopus 로고
    • The fast and slow afterhyperpolarizations are differentially modulated in hippocampal neurons by aging and learning
    • Matthews, E.A., Linardakis, J.M., Disterhoft, J.F., The fast and slow afterhyperpolarizations are differentially modulated in hippocampal neurons by aging and learning. J. Neurosci. 29 (2009), 4750–4755.
    • (2009) J. Neurosci. , vol.29 , pp. 4750-4755
    • Matthews, E.A.1    Linardakis, J.M.2    Disterhoft, J.F.3
  • 105
    • 0035978954 scopus 로고    scopus 로고
    • Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms
    • Mattson, M.P., Duan, W., Lee, J., Guo, Z., Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms. Mech. Ageing Dev. 122 (2001), 757–778.
    • (2001) Mech. Ageing Dev. , vol.122 , pp. 757-778
    • Mattson, M.P.1    Duan, W.2    Lee, J.3    Guo, Z.4
  • 106
    • 0037198042 scopus 로고    scopus 로고
    • Brain evolution and lifespan regulation: conservation of signal transduction pathways that regulate energy metabolism
    • Mattson, M.P., Brain evolution and lifespan regulation: conservation of signal transduction pathways that regulate energy metabolism. Mech. Ageing Dev. 123 (2002), 947–953.
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 947-953
    • Mattson, M.P.1
  • 107
    • 79957877029 scopus 로고    scopus 로고
    • The impact of dietary energy intake on cognitive aging
    • Mattson, M.P., The impact of dietary energy intake on cognitive aging. Front. Aging Neurosci., 2, 2010, 5.
    • (2010) Front. Aging Neurosci. , vol.2 , pp. 5
    • Mattson, M.P.1
  • 108
    • 84919770341 scopus 로고    scopus 로고
    • Challenging oneself intermittently to improve health
    • Mattson, M.P., Challenging oneself intermittently to improve health. Dose Response 12 (2014), 600–618.
    • (2014) Dose Response , vol.12 , pp. 600-618
    • Mattson, M.P.1
  • 109
    • 84923347203 scopus 로고    scopus 로고
    • Lifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence
    • Mattson, M.P., Lifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence. Ageing Res. Rev. 20 (2015), 37–45.
    • (2015) Ageing Res. Rev. , vol.20 , pp. 37-45
    • Mattson, M.P.1
  • 111
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life span and upon the ultimate body size
    • McCay, C.M., Crowell, M.F., Maynard, L.A., The effect of retarded growth upon the length of life span and upon the ultimate body size. J. Nutr. 10 (1935), 63–79.
    • (1935) J. Nutr. , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 112
  • 113
    • 84943270672 scopus 로고    scopus 로고
    • Toward rapamycin analog (rapalog)-based precision cancer therapy
    • Meng, L.H., Zheng, X.S., Toward rapamycin analog (rapalog)-based precision cancer therapy. Acta Pharmacol. Sin. 36 (2015), 1163–1169.
    • (2015) Acta Pharmacol. Sin. , vol.36 , pp. 1163-1169
    • Meng, L.H.1    Zheng, X.S.2
  • 114
    • 84921054482 scopus 로고    scopus 로고
    • Cognitive impairment, genomic instability and trace elements
    • Meramat, A., Rajab, N.F., Shahar, S., Sharif, R., Cognitive impairment, genomic instability and trace elements. J. Nutr. Health Aging 19 (2015), 48–57.
    • (2015) J. Nutr. Health Aging , vol.19 , pp. 48-57
    • Meramat, A.1    Rajab, N.F.2    Shahar, S.3    Sharif, R.4
  • 115
    • 84860920123 scopus 로고    scopus 로고
    • Of mice and men: the benefits of caloric restriction, exercise, and mimetics
    • Mercken, E.M., Carboneau, B.A., Krzysik-Walker, S.M., de Cabo, R., Of mice and men: the benefits of caloric restriction, exercise, and mimetics. Ageing Res. Rev. 11 (2012), 390–398.
    • (2012) Ageing Res. Rev. , vol.11 , pp. 390-398
    • Mercken, E.M.1    Carboneau, B.A.2    Krzysik-Walker, S.M.3    de Cabo, R.4
  • 117
    • 77955454185 scopus 로고    scopus 로고
    • Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways
    • Miller, J.A., Horvath, S., Geschwind, D.H., Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 12698–12703.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 12698-12703
    • Miller, J.A.1    Horvath, S.2    Geschwind, D.H.3
  • 119
    • 84927581733 scopus 로고    scopus 로고
    • Chronic treatment with a tryptophan-rich protein hydrolysate improves emotional processing, mental energy levels and reaction time in middle-aged women
    • Mohajeri, M.H., Wittwer, J., Vargas, K., Hogan, E., Holmes, A., Rogers, P.J., Goralczyk, R., Gibson, E.L., Chronic treatment with a tryptophan-rich protein hydrolysate improves emotional processing, mental energy levels and reaction time in middle-aged women. Br. J. Nutr., 2015, 1–16.
    • (2015) Br. J. Nutr. , pp. 1-16
    • Mohajeri, M.H.1    Wittwer, J.2    Vargas, K.3    Hogan, E.4    Holmes, A.5    Rogers, P.J.6    Goralczyk, R.7    Gibson, E.L.8
  • 121
    • 84943010207 scopus 로고    scopus 로고
    • Early intervention for cognitive decline: can cognitive training be used as a selective prevention technique?
    • Mowszowski, L., Batchelor, J., Naismith, S.L., Early intervention for cognitive decline: can cognitive training be used as a selective prevention technique?. Int. Psychogeriatr. 22 (2010), 537–548.
    • (2010) Int. Psychogeriatr. , vol.22 , pp. 537-548
    • Mowszowski, L.1    Batchelor, J.2    Naismith, S.L.3
  • 122
    • 84860890706 scopus 로고    scopus 로고
    • Comparative and meta-analytic insights into life extension via dietary restriction
    • Nakagawa, S., Lagisz, M., Hector, K.L., Spencer, H.G., Comparative and meta-analytic insights into life extension via dietary restriction. Aging Cell 11 (2012), 401–409.
    • (2012) Aging Cell , vol.11 , pp. 401-409
    • Nakagawa, S.1    Lagisz, M.2    Hector, K.L.3    Spencer, H.G.4
  • 123
    • 84988397851 scopus 로고    scopus 로고
    • National Nutrition Council., 2005. Finnish nutrition recommendations—Diet and physical activity in balance. Oy, Finland: Edita p. 57.
    • National Nutrition Council., 2005. Finnish nutrition recommendations—Diet and physical activity in balance. Oy, Finland: Edita p. 57.
  • 125
    • 84902239478 scopus 로고    scopus 로고
    • Long-term metformin usage and cognitive function among older adults with diabetes
    • Ng, T.P., Feng, L., Yap, K.B., Lee, T.S., Tan, C.H., Winblad, B., Long-term metformin usage and cognitive function among older adults with diabetes. J. Alzheimers Dis. 41 (2014), 61–68.
    • (2014) J. Alzheimers Dis. , vol.41 , pp. 61-68
    • Ng, T.P.1    Feng, L.2    Yap, K.B.3    Lee, T.S.4    Tan, C.H.5    Winblad, B.6
  • 126
    • 84938417700 scopus 로고    scopus 로고
    • SIRT1 in the brain-connections with aging-associated disorders and lifespan
    • Ng, F., Wijaya, L., Tang, B.L., SIRT1 in the brain-connections with aging-associated disorders and lifespan. Front. Cell. Neurosci., 9, 2015, 64.
    • (2015) Front. Cell. Neurosci. , vol.9 , pp. 64
    • Ng, F.1    Wijaya, L.2    Tang, B.L.3
  • 128
    • 84923057688 scopus 로고    scopus 로고
    • Resveratrol supplementation: where are we now and where should we go?
    • Novelle, M.G., Wahl, D., Dieguez, C., Bernier, M., de Cabo, R., Resveratrol supplementation: where are we now and where should we go?. Ageing Res. Rev. 21 (2015), 1–15.
    • (2015) Ageing Res. Rev. , vol.21 , pp. 1-15
    • Novelle, M.G.1    Wahl, D.2    Dieguez, C.3    Bernier, M.4    de Cabo, R.5
  • 130
    • 84929292314 scopus 로고    scopus 로고
    • Neuroprotective effects of dietary restriction: evidence and mechanisms
    • Pani, G., Neuroprotective effects of dietary restriction: evidence and mechanisms. Semin. Cell Dev. Biol. 40 (2015), 106–114.
    • (2015) Semin. Cell Dev. Biol. , vol.40 , pp. 106-114
    • Pani, G.1
  • 131
    • 84927649956 scopus 로고    scopus 로고
    • Intervening in ageing to prevent the diseases of ageing
    • Partridge, L., Intervening in ageing to prevent the diseases of ageing. Trends Endocrinol. Metab. 25 (2014), 555–557.
    • (2014) Trends Endocrinol. Metab. , vol.25 , pp. 555-557
    • Partridge, L.1
  • 132
    • 0023944266 scopus 로고
    • Studies of sequence heterogeneity of mitochondrial DNA from rat and mouse tissues: evidence for an increased frequency of deletions/additions with aging
    • Piko, L., Hougham, A.J., Bulpitt, K.J., Studies of sequence heterogeneity of mitochondrial DNA from rat and mouse tissues: evidence for an increased frequency of deletions/additions with aging. Mech. Ageing Dev. 43 (1988), 279–293.
    • (1988) Mech. Ageing Dev. , vol.43 , pp. 279-293
    • Piko, L.1    Hougham, A.J.2    Bulpitt, K.J.3
  • 135
    • 84875431034 scopus 로고    scopus 로고
    • High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebocontrolled clinicaltrial of substrate metabolism, insulin sensitivity, and body composition
    • Poulsen, M.M., Vestergaard, P.F., Clasen, B.F., Radko, Y., Christensen, L.P., Stodkilde-Jorgensen, H., Moller, N., Jessen, N., Pedersen, S.B., Jorgensen, J.O., High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebocontrolled clinicaltrial of substrate metabolism, insulin sensitivity, and body composition. Diabetes 62 (2012), 1186–1195.
    • (2012) Diabetes , vol.62 , pp. 1186-1195
    • Poulsen, M.M.1    Vestergaard, P.F.2    Clasen, B.F.3    Radko, Y.4    Christensen, L.P.5    Stodkilde-Jorgensen, H.6    Moller, N.7    Jessen, N.8    Pedersen, S.B.9    Jorgensen, J.O.10
  • 136
    • 84947209464 scopus 로고    scopus 로고
    • Repurposing metformin: an old drug with new tricks in its binding pockets
    • Pryor, R., Cabreiro, F., Repurposing metformin: an old drug with new tricks in its binding pockets. Biochem. J. 471 (2015), 307–322.
    • (2015) Biochem. J. , vol.471 , pp. 307-322
    • Pryor, R.1    Cabreiro, F.2
  • 137
    • 2542502430 scopus 로고    scopus 로고
    • ApoE genotype accounts for the vast majority of AD risk and AD pathology
    • Raber, J., Huang, Y., Ashford, J.W., ApoE genotype accounts for the vast majority of AD risk and AD pathology. Neurobiol. Aging 25 (2004), 641–650.
    • (2004) Neurobiol. Aging , vol.25 , pp. 641-650
    • Raber, J.1    Huang, Y.2    Ashford, J.W.3
  • 142
    • 84933178849 scopus 로고    scopus 로고
    • Aging alters long-term potentiation-related gene networks and impairs synaptic protein synthesis in the rat hippocampus
    • Ryan, M.M., Guevremont, D., Luxmanan, C., Abraham, W.C., Williams, J.M., Aging alters long-term potentiation-related gene networks and impairs synaptic protein synthesis in the rat hippocampus. Neurobiol. Aging 36 (2015), 1868–1880.
    • (2015) Neurobiol. Aging , vol.36 , pp. 1868-1880
    • Ryan, M.M.1    Guevremont, D.2    Luxmanan, C.3    Abraham, W.C.4    Williams, J.M.5
  • 143
    • 84902166177 scopus 로고    scopus 로고
    • Effects of insulin resistance on white matter microscructure in middle-aged and older adults
    • Ryu, S.Y., Coutu, J.P., Rosas, H.D., Salat, D.H., Effects of insulin resistance on white matter microscructure in middle-aged and older adults. Neurology 82 (2014), 1862–1870.
    • (2014) Neurology , vol.82 , pp. 1862-1870
    • Ryu, S.Y.1    Coutu, J.P.2    Rosas, H.D.3    Salat, D.H.4
  • 144
    • 20644447562 scopus 로고    scopus 로고
    • Aging, longevity, and diet: historical remarks on calorie intake reduction
    • Schafer, D., Aging, longevity, and diet: historical remarks on calorie intake reduction. Gerontology 51 (2005), 126–130.
    • (2005) Gerontology , vol.51 , pp. 126-130
    • Schafer, D.1
  • 148
    • 84960429909 scopus 로고    scopus 로고
    • Role of DHA in aging-related changes in the mouse brain synaptic plasma membrane proteome
    • Sidhu, V.K., Huang, B.X., Desai, A., Kevala, K., Kim, H.-Y., Role of DHA in aging-related changes in the mouse brain synaptic plasma membrane proteome. Neurobiol. Age 41 (2016), 73–85.
    • (2016) Neurobiol. Age , vol.41 , pp. 73-85
    • Sidhu, V.K.1    Huang, B.X.2    Desai, A.3    Kevala, K.4    Kim, H.-Y.5
  • 149
    • 84962376897 scopus 로고    scopus 로고
    • The emergence ofgeroscience as an interdisciplinary approach to the enhancement of health span and life span
    • Cold Spring Harb. Perspect. Med.
    • Sierra F., 2016. The emergence ofgeroscience as an interdisciplinary approach to the enhancement of health span and life span. Cold Spring Harb. Perspect. Med.
    • (2016)
    • Sierra, F.1
  • 150
    • 34548424059 scopus 로고    scopus 로고
    • Caloric restriction and aging revisited: the need for a geometric analysis of the nutritional bases of aging
    • Simpson, S.J., Raubenheimer, D., Caloric restriction and aging revisited: the need for a geometric analysis of the nutritional bases of aging. J. Gerontol. A: Biol. Sci. Med. Sci. 62 (2007), 707–713.
    • (2007) J. Gerontol. A: Biol. Sci. Med. Sci. , vol.62 , pp. 707-713
    • Simpson, S.J.1    Raubenheimer, D.2
  • 152
    • 84903527840 scopus 로고    scopus 로고
    • Caloric restriction and the aging process: a critique
    • Sohal, R.S., Forster, M.J., Caloric restriction and the aging process: a critique. Free Radic. Biol. Med. 73 (2014), 366–382.
    • (2014) Free Radic. Biol. Med. , vol.73 , pp. 366-382
    • Sohal, R.S.1    Forster, M.J.2
  • 153
    • 0032904685 scopus 로고    scopus 로고
    • Energetics of functional activation in neural tissues
    • Sokoloff, L., Energetics of functional activation in neural tissues. Neurochem. Res. 24 (1999), 321–329.
    • (1999) Neurochem. Res. , vol.24 , pp. 321-329
    • Sokoloff, L.1
  • 155
  • 161
    • 77956305343 scopus 로고    scopus 로고
    • Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease
    • Spilman, P., Podlutskaya, N., Hart, M.J., Debnath, J., Gorostiza, O., Bredesen, D., Richardson, A., Strong, R., Galvan, V., Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. PLoS One, 5, 2010, e9979.
    • (2010) PLoS One , vol.5 , pp. e9979
    • Spilman, P.1    Podlutskaya, N.2    Hart, M.J.3    Debnath, J.4    Gorostiza, O.5    Bredesen, D.6    Richardson, A.7    Strong, R.8    Galvan, V.9
  • 164
    • 84865635398 scopus 로고    scopus 로고
    • Does too much sugar make for lost memories?
    • Stefanidis, A., Watt, M.J., Does too much sugar make for lost memories?. J. Physiol. 590 (2012), 3633–3634.
    • (2012) J. Physiol. , vol.590 , pp. 3633-3634
    • Stefanidis, A.1    Watt, M.J.2
  • 165
    • 84937520999 scopus 로고    scopus 로고
    • ‘Activity-silent’ working memory in prefrontal cortex: a dynamic coding framework
    • Stokes, M.G., ‘Activity-silent’ working memory in prefrontal cortex: a dynamic coding framework. Trends Cogn. Sci. 19 (2015), 394–405.
    • (2015) Trends Cogn. Sci. , vol.19 , pp. 394-405
    • Stokes, M.G.1
  • 166
    • 70349262248 scopus 로고    scopus 로고
    • Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice
    • Stranahan, A.M., Lee, K., Martin, B., Maudsley, S., Golden, E., Cutler, R.G., Mattson, M.P., Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice. Hippocampus 19 (2009), 951–961.
    • (2009) Hippocampus , vol.19 , pp. 951-961
    • Stranahan, A.M.1    Lee, K.2    Martin, B.3    Maudsley, S.4    Golden, E.5    Cutler, R.G.6    Mattson, M.P.7
  • 167
    • 84889587250 scopus 로고    scopus 로고
    • Differential activation of mTOR complex 1 signaling in human brain with mild to severe Alzheimer's disease
    • Sun, Y.X., Ji, X., Mao, X., Xie, L., Jia, J., Galvan, V., Greenberg, D.A., Jin, K., Differential activation of mTOR complex 1 signaling in human brain with mild to severe Alzheimer's disease. J. Alzheimers Dis. 38 (2014), 437–444.
    • (2014) J. Alzheimers Dis. , vol.38 , pp. 437-444
    • Sun, Y.X.1    Ji, X.2    Mao, X.3    Xie, L.4    Jia, J.5    Galvan, V.6    Greenberg, D.A.7    Jin, K.8
  • 168
    • 84855886815 scopus 로고    scopus 로고
    • Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan
    • Swindell, W.R., Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan. Ageing Res. Rev. 11 (2012), 254–270.
    • (2012) Ageing Res. Rev. , vol.11 , pp. 254-270
    • Swindell, W.R.1
  • 169
    • 84893714992 scopus 로고    scopus 로고
    • Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy
    • Tan, C.C., Yu, J.T., Tan, M.S., Jiang, T., Zhu, X.C., Tan, L., Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy. Neurobiol. Aging 35 (2014), 941–957.
    • (2014) Neurobiol. Aging , vol.35 , pp. 941-957
    • Tan, C.C.1    Yu, J.T.2    Tan, M.S.3    Jiang, T.4    Zhu, X.C.5    Tan, L.6
  • 170
    • 0034994284 scopus 로고    scopus 로고
    • Life span and synapses: will there be a primary senile dementia?
    • Terry, R.D., Katzman, R., Life span and synapses: will there be a primary senile dementia?. Neurobiol. Aging 22 (2001), 347–348.
    • (2001) Neurobiol. Aging , vol.22 , pp. 347-348
    • Terry, R.D.1    Katzman, R.2
  • 171
    • 84863328591 scopus 로고    scopus 로고
    • The journey of resveratrol from yeast to human
    • Timmers, S., Auwerx, J., Schrauwen, P., The journey of resveratrol from yeast to human. Aging (Albany NY) 4 (2012), 146–158.
    • (2012) Aging (Albany NY) , vol.4 , pp. 146-158
    • Timmers, S.1    Auwerx, J.2    Schrauwen, P.3
  • 174
    • 84873122153 scopus 로고    scopus 로고
    • Functional circuits of new neurons in the dentate gyrus
    • Vivar, C., van Praag, H., Functional circuits of new neurons in the dentate gyrus. Front. Neural Circuits, 7, 2013, 15.
    • (2013) Front. Neural Circuits , vol.7 , pp. 15
    • Vivar, C.1    van Praag, H.2
  • 175
    • 0038718723 scopus 로고    scopus 로고
    • Intermittent fasting and dietary supplementation with 2-deoxy-D-glucose improve functional and metabolic cardiovascular risk factors in rats
    • Wan, R., Camandola, S., Mattson, M.P., Intermittent fasting and dietary supplementation with 2-deoxy-D-glucose improve functional and metabolic cardiovascular risk factors in rats. FASEB J. 17 (2003), 1133–1134.
    • (2003) FASEB J. , vol.17 , pp. 1133-1134
    • Wan, R.1    Camandola, S.2    Mattson, M.P.3
  • 177
    • 84903304059 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in Alzheimer's disease
    • Wang, X., Wang, W., Li, L., Perry, G., Lee, H.G., Zhu, X., Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim. Biophys. Acta 1842 (2014), 1240–1247.
    • (2014) Biochim. Biophys. Acta , vol.1842 , pp. 1240-1247
    • Wang, X.1    Wang, W.2    Li, L.3    Perry, G.4    Lee, H.G.5    Zhu, X.6
  • 179
    • 0030239808 scopus 로고    scopus 로고
    • An application of prefrontal cortex function theory to cognitive aging
    • West, R.L., An application of prefrontal cortex function theory to cognitive aging. Psychol. Bull. 120 (1996), 272–292.
    • (1996) Psychol. Bull. , vol.120 , pp. 272-292
    • West, R.L.1
  • 180
    • 84899988753 scopus 로고    scopus 로고
    • Healthy aging diets other than the mediterranean: a focus on the Okinawan diet
    • Willcox, D.C., Scapagnini, G., Willcox, B.J., Healthy aging diets other than the mediterranean: a focus on the Okinawan diet. Mech. Age Dev. 136–137 (2014), 148–162.
    • (2014) Mech. Age Dev. , vol.136-137 , pp. 148-162
    • Willcox, D.C.1    Scapagnini, G.2    Willcox, B.J.3
  • 184
    • 84908890772 scopus 로고    scopus 로고
    • Mediterranean diet interventions to prevent cognitive decline-opportunities and challenges
    • Woodside, J.V., Gallagher, N.E., Neville, C.E., McKinley, M.C., Mediterranean diet interventions to prevent cognitive decline-opportunities and challenges. Eur. J. Clin. Nutr. 68 (2014), 1241–1244.
    • (2014) Eur. J. Clin. Nutr. , vol.68 , pp. 1241-1244
    • Woodside, J.V.1    Gallagher, N.E.2    Neville, C.E.3    McKinley, M.C.4
  • 186
    • 84923358726 scopus 로고    scopus 로고
    • Cognitive health and Mediterranean diet: just diet or lifestyle pattern?
    • Yannakoulia, M., Kontogianni, M., Scarmeas, N., Cognitive health and Mediterranean diet: just diet or lifestyle pattern?. Ageing Res. Rev. 20 (2015), 74–78.
    • (2015) Ageing Res. Rev. , vol.20 , pp. 74-78
    • Yannakoulia, M.1    Kontogianni, M.2    Scarmeas, N.3
  • 187
    • 84879291943 scopus 로고    scopus 로고
    • Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism
    • Yon, M.A., Mauger, S.L., Pickavance, L.C., Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism. Br. J. Nutr. 109 (2013), 1573–1581.
    • (2013) Br. J. Nutr. , vol.109 , pp. 1573-1581
    • Yon, M.A.1    Mauger, S.L.2    Pickavance, L.C.3
  • 188
    • 84938100054 scopus 로고    scopus 로고
    • Long term consequences on spatial learning-memory of low-calorie diet durung adoloscence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in the dentate gyrus
    • Zaptan, A., Akgün-Dar, Kapucu, A., Dedeakayoğullari, H., Batu, Ş., Üzüm, G., Long term consequences on spatial learning-memory of low-calorie diet durung adoloscence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in the dentate gyrus. Brain Res. 1618 (2015), 194–204.
    • (2015) Brain Res. , vol.1618 , pp. 194-204
    • Zaptan, A.1    Akgün-Dar2    Kapucu, A.3    Dedeakayoğullari, H.4    Batu, Ş.5    Üzüm, G.6
  • 189
    • 84988410317 scopus 로고    scopus 로고
    • D.L. Longo A. Fauci D. Kasper S. Hauser J.L. Jameson J. Loscalzo 19th ed. Harrisons Principles of Internal Medicine
    • de Cabo, R., Le Couteur, D.G., Longo, D.L., Fauci, A., Kasper, D., Hauser, S., Jameson, J.L., Loscalzo, J., (eds.) The Biology of Ageing, 19th ed., 2015, Harrisons Principles of Internal Medicine.
    • (2015) The Biology of Ageing
    • de Cabo, R.1    Le Couteur, D.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.